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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (606 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
1,2,3-triazole
2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide 3,6-dibromocarbazole 4-(pyridin-4-yloxy)benzamide 5-bromoindole 5-fluorouracil ABCB1 (P-glycoprotein) actin ADME allene amides/esters androgen receptor anti-cancer activity anti-neuroinflammation anti-ovarian cancer anti-tumor anticancer anticancer activity anticancer agent anticancer agents anticancer compounds antimitotic agents antioxidant activity antiproliferative activity antiproliferative agent antitumor antitumor activity apalutamide apoptosis aromatase benzimidazole benzofuran-pyrazole benzofurans beta-lapachone bivalency breast cancer c-Met carbazole cell cycle chemical synthesis chemoresistance chrysin analogues colchiceine colchicine amide colchicine analogs colchicine sulfonamide colon cancer computational docking coumarin crystal structure cyanopyridone cytotoxic activity cytotoxic properties cytotoxicity darolutamide DFT study dihydroartemisinin dihydropyranoindole docking docking studies drug discovery drug resistance E-stereoselective enzalutamide enzyme inhibition estrone derivatives flavonoid flavonoids gemcitabine HDAC inhibitors HeLa HepG2 hydrates hydrazine IGF-1R IL-12 immune modulation indoleamine 2,3-dioxygenase inflammation inhibitor K562 kinase inhibitor MCF-7 MDM2-p53 interaction migration mimetics molecular simulation MOLT-4 multidrug resistance (MDR) reversal N-substituted pyrazoline nanoparticles natural product neuroblastoma NIH3T3 o-nitro-benzyl organosilicon compounds ortho-quinones ovarian cancer overcoming drug resistance P-glycoprotein P-MAPA PARP inhibitor PARP-1 inhibition phenylpyrazolopyrimidine photoactivatable protecting groups PI3Ks PI3Kα inhibitor PI3Kδ inhibitors polyvalency prodrug prostate cancer PROTACs protein degradation protein kinase protein-protein interactions Pyrazole pyrazolopyridine pyridotriazine quinazolin-4(3H)-one quinazolin-4(3H)-thione regioselective salinomycin Schiff base SILA-409 (Alis-409) SILA-421 (Alis-421) Src substituted pyridine synergy synthesis Talazoparib tanshione IIA taxoids thiazolidinone Thienopyrimidine thienopyrimidinone thiocolchicine thiopene thioxotriazopyridine TLR signaling topoisomerase II inhibitor triazolothiadiazine triple-negative breast cancer tryptophan metabolism tubulin inhibitors tumor specificity urea virtual screening xanthones yeast-based assays zampanolide βIII-tubulin |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (594 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
1,2,3-triazole
1,3,4-oxadiazole 3-amino-4'-guanidino 3,4'-bis-guanidino 5-fluoruracil 7-deaza-4'-thioadenosine derivatives acetamide adamantane ADC (antibody-drug conjugate) age alkylated anticancer anticancer activity anticancer agents apoptosis apoptosis induction aromatase inhibitor Bcl-2 inhibitors benzenesulfonamides benzimidazole BRAF breast cancer cancer cancer cell viability cancer vaccine CAR (chimeric antigen receptor) cardiotoxicity carvedilol cell cycle analysis chalcone chalcones colony formation combretastatin A-4 concentration-guided dosing covalent binding CovDock cumulative dose cyclophosphamide cytotoxic activity cytotoxic agents cytotoxicity designed multiple ligand diphenyl ether DNA fragmentation docking doxazosin drug efflux dual inhibitors dual-targeting molecule EGFR ELISA enantioselective synthesis entrectinib exportin-1 gastric adenocarcinoma generic product H1299 HDAC inhibitors HER2 heterocyclic compound histopathology HL-60 HT-29 cells hybrid compounds hybrid molecule hydrazide derivatives imidazoles Imiquimod immunotherapy in vitro in vivo indazole Indole-based analogues inflammation interleukin-6 intramolecular hydrogen bond isolation kidney larotrectinib letrozole MD simulations MDA-MB-231 cells mechanism prediction miR-21 mitoxantrone model informed dosing MTT cytotoxic assay MUC1 MUC16 mucin multi-kinase inhibitor multidrug resistance n/a NaMSA nitrogen scaffolds NTRK nucleoside oxidative stress patent review pemetrexed phenstatin phenyl pyridyl ether physiologically based pharmacokinetics protein kinase inhibitors resin acid solid/lipid nanoparticles sorafenib STAT inhibitors synthesis TDP1 testis thieno[2,3-d][1,2,3]triazine thiourea thymidylate synthase tissue-agnostic Toll-Like Receptor toxicity Trk Trk fusion trypan blue assay tryptophanol tubulin polymerisation inhibitor tumor spheroids tyrosil-DNA-phosphodiesterase 1 urinary bladder USFDA xanthone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
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Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Trends on Vanadium Chemistry, Biochemistry, and Medicinal Chemistry
| New Trends on Vanadium Chemistry, Biochemistry, and Medicinal Chemistry |
| Autore | Gambino Dinorah |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Research & information: general
Chemistry Inorganic chemistry |
| Soggetto non controllato |
polyoxometalates
decavanadate cytotoxicity insulin-like activity diabetes therapy vanadium biochemistry vanadium speciation vanadium proteins DNA fluorescence binding constants mechanism of action oxidovanadium(V) vanadium Schiff base coordination complex low acute toxicity Oxidovanadium(V) Schiff base X-ray crystallography DNA interaction 2-aminopyrimidinium experimental and theoretical characterization DFT docking RNA/DNA vitamin E EPR tocopherol 51V NMR urethane aerosol delivery lung cancer apoptosis antineoplastic oxidovanadium(IV) phenantrholine chrysin vanadium cellular uptake anticancer albumin interaction glycosylated flavonoid oxidovanadium(IV) complex antitumoral antioxidant cell signaling cancer anticancer agents |
| ISBN | 3-0365-5765-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637783803321 |
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Gambino Dinorah
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Unconventional Anticancer Metallodrugs and Strategies to Improve their Pharmacological Profile / Maria Contel
| Unconventional Anticancer Metallodrugs and Strategies to Improve their Pharmacological Profile / Maria Contel |
| Autore | Contel Maria |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
?-? stacking
encapsulation oxindolimine-metal complexes cyclodextrin platinum iodido complexes distribution coefficient antiproliferative activity anticancer agents nanotubes ruthenium platinum Log kw nanoparticles drug discovery metal complex metallodrugs isatin-derived ligands anticancer drug upconverting nanoparticles pyridine benzimidazole dendrimers liposomes thiophene angiogenesis micelles HSA oxidation platinum(IV) imaging chromatographic lipophilicity parameter amidophosphine copper and iron chelators in cancer Log P biomacromolecules bones DNA cleavage stopped-flow spectroscopy silver phosphonates transmetalation metallomics MRI fluorescence quenching partition coefficient gold fingers anticancer HSA binding gold ?0 targeting metastasis DNA interaction antimigration cytotoxicity HPLC ruthenium complexes zinc finger proteins Gold(III) complexes aquaporins antiproliferative protein-DNA recognition photoactivation lipophilicity cancer 1-methylcytosine PET |
| ISBN |
9783039213160
3039213164 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367755103321 |
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Contel Maria
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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