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Integrative Multi-Omics in Biomedical Research
| Integrative Multi-Omics in Biomedical Research |
| Autore | Gerner Christopher |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (178 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
acute myeloid leukemia
analysis flow anti-angiogenesis ATRA Barrett's esophagus batch variations bioinformatics cardiac metaplasia cGAS cheminformatics curcumin DNA sensing eicosanoids endometriosis esophageal adenocarcinoma exercise fetal calf serum heart HL-60 cell line host-pathogen interactions IFI16 induced differentiation inflammation innate immunity key molecules label-free method for drugs lipid lipidomics machine learning macrophages mass spectrometry mechanism of action metabolomics microbiota multi-omics multi-omics analysis myocardial infarction (MI) n/a natural products peroxisomes planned myocardial infarction (PMI) post-translational modifications protein interactions proteome proteomics receptor tyrosine kinases regulatory pathway modelling secretome SRM study design target identification target validation transcription factors transcriptome transcriptomics virus-host interactions |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557769003321 |
Gerner Christopher
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (480 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
12-deacetyl-12-epi-scalaradial
3-alkylpyridinium polymers A375 and HeLa cell lines A549 cells ABC transporter actinomycin AD0157 adriamycin resistance Aeroplysinin Akt angiogenesis angiogenesis inhibitor ansamycins anthranilic acid anti-angiogenesis anti-angiogenic anti-cancer anti-metastatic activity anti-proliferation anti-proliferative antiangiogenesis antiangiogenic antibacterial Antibody Drug Conjugates (ADCs) anticancer anticancer activity anticancer agent anticancer immunity anticarcinogenic anticoagulant anticoagulation antifouling Antimicrobial peptide (AMP) antioxidant antiproliferative antiproliferative activity antitumor antitumor activities antitumoral antitumour AP-1 apoptosis apoptosis-inducing activity approved antitumor agents araguspongine C arrest of cell cycle Aspergillus autophagy autophagy inducers autophagy inhibitors azoxymethane BCRP/ABCG2 BEL-7402 cell benzo[a]pyrene bioactive natural product bioanalysis bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) bonnethead shark breast cancer breast cancer cells Brevianamide brominated indoles bromophenol buccal gland c-JUN c-Met C15 acetogenins camptothecin cancer Cancer cancer genes cancer preventive cancer progression Cantabrian Sea-derived actinobacteria carbocyclic analogue carcinoembryonic antigen Caribbean sponge carotenoid carotenoids caspase cascade cell adhesion cell adhesion molecules cell cycle cell cycle arrest cell migration cembranoids chemical conjugation chemoprevention chemopreventive chemosensitization chemotherapy chimera CHOP chromatography circulating tumor cells cisplatin clinical trials colorectal cancer cooperative binding cyclin D1 cyclin-dependent kinase CYP1A1 cystatin F cystatin superfamily cytokine release cytoskeleton cytotoxic activity cytotoxicity deep-sea depolymerisation dibromotyrosine dieckol divergolides DNA minor groove binder drug discovery Ecklonia cava elisidepsin EMT endoperoxide endophytic fungus endothelial cells energy stress epigonal organ epithelial-mesenchymal transition ER-stress ET-743 evolution FAK fascaplysin fatty acid 2-hydroxylase fatty acids FAU FBDD fucoidan fucoxanthin fumigaclavine C gemcitabine gene expression glioblastoma gliotoxin glucocorticoid receptor glycosaminoglycans gorgonian Haliclona gracilis HeLa cells heparan sulphate heparanase hepatocellular carcinoma HER2 HIF-1 hippuristanol HSP90 human lung cancer human normal diploid fibroblast (TIG-1 cells) human sarcoma cell line (HT1080 cells) humulane sesquiterpenoids hybridization hydroxylated lipids hypoxia hypoxia-inducible factor-1 IL-6 in vivo model inflammation inhibitor integrin β1 invasion isatin Isofistularin itampolin A jaspine B JNK1/2 Jurkat kalkitoxin kunitz type inhibitor Lampetra morii Leathesia nana Leptogorgia leukemia lipid rafts low molecular weight fucoidan extract low toxic LS-1 lung cancer lung metastasis Lyngbya majuscula macrolide mangrove-derived actinomycete manzamine A MAPK/ERK pathway marangucyclines marine antitumor agents marine biotechnology marine compound marine drug marine drugs marine fungus marine metabolites marine mollusc marine natural products marine organisms marine sponges marine-derived drugs Marthasterias glacialis L. MCP-1 mechanisms of action melanoma membrane permeabilization metastasis microalgae Micromonospora migration mitochondria mitochondria toxin mitochondrial pathway mitochondrial dysfunction molecular docking molecular mechanisms molecular modeling molecular oncology Moorea producens MRP1/ABCC1 multi-drug resistant leukemia multidrug resistance Mycalin A Mycochromenic acid derivative N-Ras n/a nanoparticle naphthopyrones natural marine compounds natural product natural products neuroblastoma-rat sarcoma NF-κB NF-κB signaling nicotine nicotinic acetylcholine receptor non-small cell lung cancer non-small cell lung cancer (NSCLC) non-small cell lung carcinoma nonfunctioning pituitary adenomas novel inhibitor NSCLC Nur77 osteosarcoma oxidative stress oxidative stress P-gp/ABCB1 P2X7 receptor p38 p38/ERK p38α p65 pachastrissamine palmitic acid paulomycins pazopanib PEL Penicillium brevicompactum Penicillium paneum phase I pheochromocytoma and paraganglioma phlorotannins phycocyanin PI3K/Akt plakortide plitidepsin pollution poly(ADP-ribose)-polymerase inhibitor polyoxygenated steroids polyphenols polysaccharides Porifera porifera/sponge preclinical programmed cell death programmed cell death-ligand 1 programmed cell death-ligand 2 proliferation prostate cancer proteasomal degradation proteomic pseudopterosin puupehenones pyrrolidinedione reactive oxygen species RGD motif ribosomal protein genes ROS RPS30 safety Sarcophyton ehrenbergi sea anemone sea cucumbers seaweed secondary metabolites sediment selenium-containing polysaccharide-protein complex Sepia ink polysaccharides shrimp signal transduction sinulariolide sipholenol A small cell lung cancer SNORA62 snoRNA SNU-C5/5-FU soft coral soft tissue sarcoma soft tissue sarcoma sphingosine kinase inhibitor sponge sponges STAT3 Streptomyces sp. SCSIO 11594 synergism synthetic analogues SZ-685C targeted therapy terpenes tetracenomycin X TGF-β signaling Thalassia testudinum thalassiolin B therapeutic compounds Tilapia piscidin 4 (TP4) TNFα Topo I inhibitor topoisomerase trabectedin triterpene glycosides TRPM7 tumor cell line tumor microenvironment tumor-associated macrophages Ulva fasciata uveal melanoma VEGF virtual screening xyloketal B α9-nicotinic acetylcholine receptors (nAChRs) αO-conotoxin GeXIVA β1-integrin λ-carrageenan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Products from Marine Fungi
| Natural Products from Marine Fungi |
| Autore | Shin Hee Jae |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (160 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
natural products
extremophilic fungi biological activity deep-sea derived fungus Phialocephala sp nitrogen-containing sorbicillinoids radical scavenging activity sponge-derived fungus Alternaria sp perylenequinone derivatives X-ray single crystal diffraction cytotoxic activity antibacterial Phomopsis lithocarpus benzophenone derivatives eremophilane derivative aspochalasin tricyclic fused gut fungus cytotoxicity endophytic fungus Myrothecium sp meroterpenoids isocoumarinoids α-glucosidase inhibitors salt-resistant plant Apocynum venetum Fusarium solani H915 bis-alkenoic acid esters fusaridioic acid A fusariumester A1 fusariumester A2 fusariumester B tea pathogenic fungi inhibitory effect herqueinones phenalenones Penicillium sp marine-derived fungi adipogenesis anti-angiogenesis anti-inflammatory marine-derived fungus Aspergillus versicolor diketopiperazine anthraquinone derivatives Sporendonema casei cytotoxic activities antibacterial activities |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557287603321 |
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Shin Hee Jae
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Treatment Strategies for Glioblastoma
| Novel Treatment Strategies for Glioblastoma |
| Autore | Stylli Stanley |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (268 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
angiopoietin (Ang)
anti-angiogenesis anticancer brain cancer brain tumor cancer stem cell cancer stem cell niche cancer stem cells cell cycle chimeric antigen receptor (CAR) T cells CK2 CRISPR/Cas9 CX-4945 de novo purine synthesis differentiation drug repurposing drug targets drug-inducible gene expression endothelial nitric oxide synthase (eNOS) GBM gene therapy glioblastoma glioblastoma (GB) glioblastoma multiforme glioma immune checkpoint inhibitors immunotherapy invadopodia invasion ion channels Mardepodect metabolic reprogramming metabolic treatment migration n/a nanomedicine nerve/glial antigen 2 new trial design newly diagnosed glioblastoma NG2 novel therapy one-carbon metabolism organoids P-bi-TAT P-m-TAT PEG personalized treatment pluripotent stem cells proliferation prolyl-oligopeptidase (POP) radiotherapy RAS recurrent glioblastoma Regorafenib renin-angiotensin system SRGAP2 stem cell targeted therapy temozolomide tetrac thyrointegrin αvβ3 TP53 transforming growth factor-β (TGF-β) triazole tetrac tumor antigens tumor microenvironment vaccine vascular endothelial growth factor (VEGF) viral vectors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557363703321 |
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Stylli Stanley
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances in Antibody Therapeutics
| Recent Advances in Antibody Therapeutics |
| Autore | Heo Yong-Seok |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (238 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
affinity maturation
agonist antibody anti-angiogenesis anti-cancer antibody antibodies antibody antibody engineering antibody therapeutics antibody therapy antibody-drug conjugates antigen asthma atherosclerosis binding assays bioassays biochemical and physicochemical properties biomarker biophysical properties bispecific antibodies bladder cancer blood-brain barrier brain shuttle C2_2E12 cell fate combinatorial antibody library computational methods cost-effectiveness cytomegalovirus delta-like ligand disposition enfortumab vedotin erdafitinib Fc binding G protein-coupled receptor HPV cancer therapy HPV oncoproteins HPV-associated cancer Human papillomaviruses immune checkpoint inhibitors inflammation interleukin 33 intracellular antibodies irinotecan mechanisms of action membrane protein molecular Trojan horse monoclonal antibody n/a nanobody paclitaxel peptide/major histocompatibility complex class I complex phage display pharmacokinetics potency assays receptor-binding domain receptor-mediated transcytosis recombinant antibodies refractory asthma research cell bank sacituzumab govitecan SARS-CoV-2 scFv single-chain antibody fragment spike protein ST2 receptor T-cell-receptor-like antibody therapeutic antibody transferrin VEGF yeast surface display |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580204803321 |
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Heo Yong-Seok
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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