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Development and application of herbal medicine from marine origin / / special issue editors, Tsong-Long Hwang, Ping-Jyun Sung, Chih-Chuang Liaw
| Development and application of herbal medicine from marine origin / / special issue editors, Tsong-Long Hwang, Ping-Jyun Sung, Chih-Chuang Liaw |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (140 p.) |
| Disciplina | 615.3/21 |
| Soggetto topico |
Herbs - Therapeutic use
Marine pharmacology Marine algae - Therapeutic use |
| Soggetto non controllato |
marine functional foods
vascular endothelial growth factor receptor-3 ultrafiltration lung fibrosis metabolic instability peptide fractions cembrane 3T3 fibroblasts Pinnigorgia sp lymphatic endothelial cells bile salts caspase-3 cytokine hepatic stellate cells macrophage oral squamous cell carcinoma anti-inflammation MAPK fucoidan Jaspine B ACE-inhibition bioactivity sulfated galactan bioavailability ROS anti-angiogenesis briarellin neolignan radiation pneumonitis Pachyclavularia Lumnitzera racemosa apoptosis phomaketide A prodigiosin neutrophil intestinal permeability autophage secosterol octocoral amino acids composition phlorotannins cardiovascular-health antioxidant properties marine viva green seaweed protein enzymatic hydrolysate lymphangiogenesis edible brown algae briarane |
| ISBN | 3-03921-222-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346673403321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Integrative Multi-Omics in Biomedical Research
| Integrative Multi-Omics in Biomedical Research |
| Autore | Gerner Christopher |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (178 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
target identification
target validation label-free method for drugs anti-angiogenesis mechanism of action receptor tyrosine kinases curcumin natural products lipid lipidomics cardiac metaplasia Barrett's esophagus esophageal adenocarcinoma microbiota DNA sensing IFI16 cGAS innate immunity protein interactions virus-host interactions post-translational modifications mass spectrometry proteomics transcriptomics multi-omics multi-omics analysis study design bioinformatics machine learning analysis flow metabolomics planned myocardial infarction (PMI) myocardial infarction (MI) exercise heart cheminformatics batch variations eicosanoids fetal calf serum peroxisomes host-pathogen interactions secretome macrophages acute myeloid leukemia HL-60 cell line ATRA induced differentiation transcriptome proteome transcription factors key molecules regulatory pathway modelling SRM endometriosis inflammation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557769003321 |
Gerner Christopher
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
apoptosis
fucoidan hepatocellular carcinoma reactive oxygen species 3-alkylpyridinium polymers nicotine nicotinic acetylcholine receptor non-small cell lung carcinoma melanoma sinulariolide proteomic mitochondria caspase cascade marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity dibromotyrosine mitochondrial dysfunction oxidative stress topoisomerase epigonal organ bonnethead shark Jurkat tumor cell line hippuristanol PEL AP-1 STAT3 Akt colorectal cancer marine mollusc brominated indoles shrimp chemoprevention fatty acids carotenoids cancer nanoparticle osteosarcoma lung metastasis elisidepsin lipid rafts hydroxylated lipids fatty acid 2-hydroxylase cooperative binding membrane permeabilization marine organisms polysaccharides anticancer anticarcinogenic mechanisms of action fumigaclavine C anti-proliferation mitochondrial pathway anti-cancer anti-proliferative carotenoid cell cycle arrest fucoxanthin azoxymethane bioactive natural product isatin in vivo model Marthasterias glacialis L. palmitic acid ER-stress CHOP Antibody Drug Conjugates (ADCs) marine antitumor agents clinical trials approved antitumor agents AD0157 angiogenesis marine drug pyrrolidinedione secondary metabolites cancer preventive chemopreventive trabectedin plitidepsin tumor-associated macrophages tumor microenvironment preclinical anticancer immunity antiangiogenesis fascaplysin cyclin-dependent kinase small cell lung cancer camptothecin poly(ADP-ribose)-polymerase inhibitor breast cancer seaweed therapeutic compounds autophagy marine drugs autophagy inhibitors autophagy inducers macrolide programmed cell death energy stress araguspongine C c-Met HER2 gemcitabine pazopanib phase I safety soft tissue sarcoma pachastrissamine jaspine B carbocyclic analogue sphingosine kinase inhibitor molecular modeling ET-743 DNA minor groove binder soft tissue sarcoma chemotherapy bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) anti-metastatic activity cell adhesion β1-integrin FAK BEL-7402 cell triterpene glycosides sea cucumbers antitumor activities arrest of cell cycle antibacterial marangucyclines deep-sea Streptomyces sp. SCSIO 11594 LS-1 SNU-C5/5-FU TGF-β signaling carcinoembryonic antigen kalkitoxin Moorea producens mitochondria toxin VEGF angiogenesis inhibitor hypoxia-inducible factor-1 HIF-1 Lyngbya majuscula marine metabolites SZ-685C nonfunctioning pituitary adenomas Ecklonia cava phlorotannins dieckol migration sipholenol A ABC transporter multidrug resistance P-gp/ABCB1 BCRP/ABCG2 MRP1/ABCC1 marine natural products glioblastoma xyloketal B proliferation TRPM7 marine compound ribosomal protein genes snoRNA FAU RPS30 SNORA62 evolution Porifera Penicillium brevicompactum Brevianamide Mycochromenic acid derivative antifouling Caribbean sponge plakortide endoperoxide leukemia multi-drug resistant leukemia Sarcophyton ehrenbergi soft coral terpenes cembranoids cytotoxic activity molecular docking uveal melanoma oxidative stress virtual screening Topo I inhibitor low toxic natural product Ulva fasciata selenium-containing polysaccharide-protein complex pseudopterosin NF-κB p65 inflammation cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor paulomycins Micromonospora antitumor Cantabrian Sea-derived actinobacteria puupehenones sponges antiangiogenic antitumoral porifera/sponge cancer genes molecular oncology bromophenol molecular mechanisms cell cycle PI3K/Akt p38/ERK ROS human lung cancer glycosaminoglycans antiproliferative heparan sulphate gliotoxin NSCLC adriamycin resistance Sepia ink polysaccharides antitumour chemosensitization anticoagulation sea anemone drug discovery endothelial cells RGD motif kunitz type inhibitor prostate cancer antioxidant natural marine compounds marine biotechnology microalgae marine sponges Aeroplysinin Isofistularin pheochromocytoma and paraganglioma metastasis cancer progression cell adhesion molecules integrin β1 hypoxia phycocyanin non-small cell lung cancer NF-κB signaling marine-derived drugs bioanalysis chromatography manzamine A epithelial-mesenchymal transition lung cancer circulating tumor cells signal transduction cisplatin Lampetra morii buccal gland cystatin F anti-angiogenesis cystatin superfamily Antimicrobial peptide (AMP) Tilapia piscidin 4 (TP4) non-small cell lung cancer (NSCLC) itampolin A FBDD p38α novel inhibitor tetracenomycin X cyclin D1 proteasomal degradation p38 c-JUN λ-carrageenan heparanase anticoagulant depolymerisation cell migration Aspergillus naphthopyrones endophytic fungus Leathesia nana mangrove-derived actinomycete ansamycins divergolides apoptosis-inducing activity actinomycin EMT invasion low molecular weight fucoidan extract N-Ras neuroblastoma-rat sarcoma Cancer programmed cell death-ligand 1 programmed cell death-ligand 2 human sarcoma cell line (HT1080 cells) human normal diploid fibroblast (TIG-1 cells) chimera chemical conjugation anticancer agent hybridization α9-nicotinic acetylcholine receptors (nAChRs) breast cancer cells αO-conotoxin GeXIVA targeted therapy gorgonian Leptogorgia humulane sesquiterpenoids anticancer activity 12-deacetyl-12-epi-scalaradial HeLa cells Nur77 MAPK/ERK pathway Mycalin A C15 acetogenins synthetic analogues antiproliferative activity A375 and HeLa cell lines polyoxygenated steroids sponge Haliclona gracilis Thalassia testudinum thalassiolin B polyphenols CYP1A1 benzo[a]pyrene JNK1/2 natural products synergism A549 cells cytoskeleton P2X7 receptor pollution anti-angiogenic gene expression HSP90 inhibitor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Products from Marine Fungi
| Natural Products from Marine Fungi |
| Autore | Shin Hee Jae |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (160 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
natural products
extremophilic fungi biological activity deep-sea derived fungus Phialocephala sp nitrogen-containing sorbicillinoids radical scavenging activity sponge-derived fungus Alternaria sp perylenequinone derivatives X-ray single crystal diffraction cytotoxic activity antibacterial Phomopsis lithocarpus benzophenone derivatives eremophilane derivative aspochalasin tricyclic fused gut fungus cytotoxicity endophytic fungus Myrothecium sp meroterpenoids isocoumarinoids α-glucosidase inhibitors salt-resistant plant Apocynum venetum Fusarium solani H915 bis-alkenoic acid esters fusaridioic acid A fusariumester A1 fusariumester A2 fusariumester B tea pathogenic fungi inhibitory effect herqueinones phenalenones Penicillium sp marine-derived fungi adipogenesis anti-angiogenesis anti-inflammatory marine-derived fungus Aspergillus versicolor diketopiperazine anthraquinone derivatives Sporendonema casei cytotoxic activities antibacterial activities |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557287603321 |
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Shin Hee Jae
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Treatment Strategies for Glioblastoma
| Novel Treatment Strategies for Glioblastoma |
| Autore | Stylli Stanley |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (268 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
glioblastoma
glioma temozolomide radiotherapy immunotherapy novel therapy personalized treatment drug repurposing invasion invadopodia ion channels gene therapy viral vectors brain tumor nanomedicine cancer stem cell targeted therapy brain cancer cell cycle differentiation proliferation RAS SRGAP2 stem cell TP53 glioblastoma multiforme GBM nerve/glial antigen 2 NG2 CK2 CX-4945 migration CRISPR/Cas9 anticancer anti-angiogenesis thyrointegrin αvβ3 PEG triazole tetrac P-bi-TAT P-m-TAT tetrac one-carbon metabolism de novo purine synthesis metabolic reprogramming metabolic treatment vaccine immune checkpoint inhibitors chimeric antigen receptor (CAR) T cells glioblastoma (GB) prolyl-oligopeptidase (POP) vascular endothelial growth factor (VEGF) transforming growth factor-β (TGF-β) angiopoietin (Ang) endothelial nitric oxide synthase (eNOS) newly diagnosed glioblastoma recurrent glioblastoma new trial design drug-inducible gene expression Mardepodect Regorafenib drug targets tumor antigens renin-angiotensin system pluripotent stem cells organoids cancer stem cells cancer stem cell niche tumor microenvironment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557363703321 |
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Stylli Stanley
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances in Antibody Therapeutics
| Recent Advances in Antibody Therapeutics |
| Autore | Heo Yong-Seok |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
interleukin 33
ST2 receptor scFv C2_2E12 bladder cancer antibodies immune checkpoint inhibitors antibody-drug conjugates sacituzumab govitecan enfortumab vedotin erdafitinib cost-effectiveness G protein-coupled receptor membrane protein antigen therapeutic antibody anti-angiogenesis delta-like ligand irinotecan paclitaxel VEGF SARS-CoV-2 spike protein receptor-binding domain phage display monoclonal antibody cytomegalovirus peptide/major histocompatibility complex class I complex T-cell-receptor-like antibody affinity maturation yeast surface display combinatorial antibody library agonist antibody cell fate bispecific antibodies bioassays mechanisms of action binding assays potency assays atherosclerosis inflammation antibody therapy blood-brain barrier antibody pharmacokinetics disposition biochemical and physicochemical properties Fc binding receptor-mediated transcytosis brain shuttle molecular Trojan horse transferrin anti-cancer antibody antibody engineering biophysical properties computational methods research cell bank antibody therapeutics recombinant antibodies intracellular antibodies single-chain antibody fragment nanobody Human papillomaviruses HPV oncoproteins HPV-associated cancer HPV cancer therapy asthma refractory asthma biomarker |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580204803321 |
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Heo Yong-Seok
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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