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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (606 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
1,2,3-triazole
2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide 3,6-dibromocarbazole 4-(pyridin-4-yloxy)benzamide 5-bromoindole 5-fluorouracil ABCB1 (P-glycoprotein) actin ADME allene amides/esters androgen receptor anti-cancer activity anti-neuroinflammation anti-ovarian cancer anti-tumor anticancer anticancer activity anticancer agent anticancer agents anticancer compounds antimitotic agents antioxidant activity antiproliferative activity antiproliferative agent antitumor antitumor activity apalutamide apoptosis aromatase benzimidazole benzofuran-pyrazole benzofurans beta-lapachone bivalency breast cancer c-Met carbazole cell cycle chemical synthesis chemoresistance chrysin analogues colchiceine colchicine amide colchicine analogs colchicine sulfonamide colon cancer computational docking coumarin crystal structure cyanopyridone cytotoxic activity cytotoxic properties cytotoxicity darolutamide DFT study dihydroartemisinin dihydropyranoindole docking docking studies drug discovery drug resistance E-stereoselective enzalutamide enzyme inhibition estrone derivatives flavonoid flavonoids gemcitabine HDAC inhibitors HeLa HepG2 hydrates hydrazine IGF-1R IL-12 immune modulation indoleamine 2,3-dioxygenase inflammation inhibitor K562 kinase inhibitor MCF-7 MDM2-p53 interaction migration mimetics molecular simulation MOLT-4 multidrug resistance (MDR) reversal N-substituted pyrazoline nanoparticles natural product neuroblastoma NIH3T3 o-nitro-benzyl organosilicon compounds ortho-quinones ovarian cancer overcoming drug resistance P-glycoprotein P-MAPA PARP inhibitor PARP-1 inhibition phenylpyrazolopyrimidine photoactivatable protecting groups PI3Ks PI3Kα inhibitor PI3Kδ inhibitors polyvalency prodrug prostate cancer PROTACs protein degradation protein kinase protein-protein interactions Pyrazole pyrazolopyridine pyridotriazine quinazolin-4(3H)-one quinazolin-4(3H)-thione regioselective salinomycin Schiff base SILA-409 (Alis-409) SILA-421 (Alis-421) Src substituted pyridine synergy synthesis Talazoparib tanshione IIA taxoids thiazolidinone Thienopyrimidine thienopyrimidinone thiocolchicine thiopene thioxotriazopyridine TLR signaling topoisomerase II inhibitor triazolothiadiazine triple-negative breast cancer tryptophan metabolism tubulin inhibitors tumor specificity urea virtual screening xanthones yeast-based assays zampanolide βIII-tubulin |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Assessing prenatal and neonatal gonadal steroid exposure for studies of human development [[electronic resource] ] : methodological and theoretical challenges / / edited by Rebecca Christine Knickmeyer, Marsha L. Davenport and Bonnie Auyeung
| Assessing prenatal and neonatal gonadal steroid exposure for studies of human development [[electronic resource] ] : methodological and theoretical challenges / / edited by Rebecca Christine Knickmeyer, Marsha L. Davenport and Bonnie Auyeung |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 online resource (80 pages) : illustrations; digital, PDF file(s) |
| Collana | Frontiers Research Topics. |
| Soggetto topico | Endocrinology |
| Soggetto non controllato |
minipuberty
Testosterone androgen receptor digit ratio prenatal sexual differentiation umbilical cord blood Opposite-sex twins Saliva Hypogonadism |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137098403321 |
| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Natural Products from the Red Sea
| Bioactive Natural Products from the Red Sea |
| Autore | Rateb Mostafa |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (152 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
Actinokineospora
Alternaria androgen receptor anti-inflammatory antibacterial antibiofilm antimalarial antimicrobial antimicrobial activities Aspergillus falconensis azaphilones bioactivity biodiversity ceramide cerebroside co-cultivation co-culture cytotoxic cytotoxic activity diketopiperazine alkaloids DNA gyrase docking docking studies Epicoccum epicotripeptin ergosterol derivative halogenated 3-phenylpropanoic acid derivatives LC-HRESIMS marine actinomycetes marine metagenomics marine natural products marine organisms metabolic analysis metabolomics n/a neuroprotective NF-κB inhibition OSMAC phenazine phragamide pyruvate kinase Red Sea Red Sea sponges Rhodococcus seagrass Sinularia polydactyla soft coral sponge-associated actinomycetes steroids Streptomyces coelicolor LY001 structural determinations Stylissa carteri Thalassodendron ciliatum X-ray diffraction |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557540903321 |
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Rateb Mostafa
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination
| Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination |
| Autore | Alix-Panabieres Catherine |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (366 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
abiraterone
ACCEPT androgen receptor AR AR-V7 ARV7 biomarker biomarkers bone marrow breast cancer castration resistant prostate cancer (CRPC) CD133 CellSearch CellSearch® cerebrospinal liquid biopsy chemoradioresistance chromogranin A circulating leukemia cells circulating plasma cells circulating tumor cells circulating tumor cells (CTC) circulating tumor cells (CTCs) circulating tumor DNA circulating tumour cells clinical trials clinical utility colorectal cancer colorectal surgery CTC CTC biology CTC capture technology CTC-based treatment decisions CTC-derived ex vivo models CTC-derived xenografts CTCs ctDNA CTM CTMat ctRNA disseminated tumor cells early breast cancer EasyCount slides emboli enrichment and detection technologies enzalutamide EpCAM enrichment EPISPOT epithelial-mesenchymal transition epithelial-to-mesenchymal transition (EMT) exosome exosomes fibronectin fish flow cytometry FOLFIRINOX gene expression analysis glioma hematological cells hepatocellular carcinoma (HCC) heterogeneity HMB-45 immune checkpoint inhibitors immune system immunofluorescence imaging immunomodulation immunophenotyping in vivo flow cytometry integrin B1 leukocyte-derived extracellular vesicles liquid biopsy liquid surgery locally advanced rectal cancer major histocompatibility complex class I (MHCI) malaria melanoma metastasis metastatic colorectal cancer microbiome microfluidics microsatellite instability miRNA n/a neutrophils NSCLC PD-L1 expression platelets prostate cancer prostate cancer (PCa) RAD23B rovalpituzumab tesirine rVAR2 single-cell analysis SLUG small-cell lung carcinoma solid cancers stem cells synaptophysin targeted therapy thymidylate synthase tumor biomarkers tumor cell dissemination tumor stem cells tumor-initiating cells (TICs) xenograft models |
| ISBN | 3-03928-699-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Circulating Tumor Cells |
| Record Nr. | UNINA-9910404091403321 |
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Alix-Panabieres Catherine
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications
| Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications |
| Autore | Ishii Kenichiro |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (184 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
abiraterone
AKR1C3 androgen deprivation therapy androgen receptor androgen receptor dependency androgen sensitivity animal model apoptosis autophagy cabazitaxel CAF castration resistant prostate cancer castration-resistant prostate cancer Caveolin-1 CCL2 CCL22 CCL5 chemotherapy CW069 cytokine diet docetaxel docetaxel resistance enzalutamide EPI-002 epigenetics fat fibroblast fibroblast growth factor fibroblast growth factor receptor fibroblast-dependent androgen receptor activation fibroblasts G1 cell cycle arrest high-fat diet hormone-naïve prostate cancer immune cells immunohistochemistry in vitro in vivo inflammation KIFC1 LSD1 migration mouse n/a obesity P-glycoprotein pirfenidone prostate cancer prostate-specific antigen radiotherapy resistance splice variant testosterone TGFβ1 time to PSA nadir tissue microarray TP53-regulated inhibitor of apoptosis 1 tumour microenvironment tumour stroma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557116703321 |
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Ishii Kenichiro
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diagnostic, Prognostic and Predictive Biological Markers in Bladder Cancer - Illumination of a Vision 2.0
| Diagnostic, Prognostic and Predictive Biological Markers in Bladder Cancer - Illumination of a Vision 2.0 |
| Autore | Ecke Thorsten |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (240 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adjuvant chemotherapy
androgen receptor BCG therapy biomarker biomarkers BIRC5 bladder bladder cancer bladder cancer detection cadmium exposure cancer chemotherapy combination therapy DNA methylation drug resistance ECRG4 ERBB2 F-actin FGFR3 grade heparan sulfate proteoglycans (HSPGs) heparanase histone demethylase immunotherapy invasion ITIH5 JAK inhibitor JAK-STAT pathway KDM7A KRT20 macrophage metabolomics Metallothionein MIBC miRNA MS muscle-invasive bladder cancer n/a NMR non muscle invasive bladder cancer non-invasive detection oncolytic adenovirus p53 personalized medicine prediction predictive biomarker prognosis proliferation PTEN quantitative PCR RT-qPCR somatic mutations STAT3/5 inhibitor survival survivin syndecan-1 TAGLN TC-E 5002 telomerase TERT promoter mutations TERT promoter region tumor marker tumor markers tumorigenesis urinary biomarkers urothelial cancer urothelial carcinoma urothelium virotherapy voided urine cytology XVir-N-31 zinc transporter |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557142003321 |
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Ecke Thorsten
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sex Hormone Receptor Signals in Human Malignancies / Hiroshi Miyamoto
| Sex Hormone Receptor Signals in Human Malignancies / Hiroshi Miyamoto |
| Autore | Miyamoto Hiroshi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (152 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
FOXA1
COBRA1 estrogen progesterone receptor negative mutational profiling heterogeneous nuclear ribonucleoprotein K estrogen receptor alpha salivary gland tumors castration-resistant prostate cancer ELK1 fibroblasts androgen receptor melanocytes drug screening and proteomics PI3K pathway NELFB therapeutic targets immunohistochemistry androgen deprivation therapy ovarian cancer estrogen receptor epidermal growth factor receptor ethinylestradiol melanoma breast cancer keratinocytes G-protein coupled estrogen receptor prognosis levonorgestrel ultraviolet radiation sex hormone receptors upper urinary tract urothelial carcinoma CRPC nuclear factor erythroid 2-related factor 2 TP53 |
| ISBN |
9783039211746
3039211749 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756503321 |
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Miyamoto Hiroshi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Urological Cancer 2020
| Urological Cancer 2020 |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (334 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
[68Ga]Ga-PSMA PET/CT
androgen receptor androgen response angiogenesis angiogenic growth factors anoikis antiangiogenic therapy artificial intelligence biomarker biphasic imaging bladder cancer cell proliferation chelation therapy CPT1A CXCL9 deep learning delayed imaging diagnosis differential diagnosis DONSON Downstream Neighbor of SON dual-time point imaging en-bloc resection fatty acids histopathology immunohistochemistry iron KLF5 lesion positivity rate machine learning macrophages MAP1B metastatic spread microtubule MR-guided MRgRT n/a neural network oncogenes online adaptive optical mapping oxidative stress patient-derived xenografts PD-L1 PD1 precision medicine prevention prognosis prostate cancer prostate carcinoma prostate mpMRI prostatic neoplasms/epidemiology prostatic neoplasms/mortality radiotherapy RCC renal cell cancer renal cell carcinoma renal tumors research model ROS SEER Program serine stage T1 NMIBC stereotactic ablative radiation therapy (SABR) stereotactic ablative radiotherapy stroma signature therapy transcriptome transurethral resection tumor suppressor genes tumorigenesis urothelial carcinoma vascularity whole genome sequencing α1-adrenoceptor antagonists |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557354903321 |
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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