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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Assessing prenatal and neonatal gonadal steroid exposure for studies of human development [[electronic resource] ] : methodological and theoretical challenges / / edited by Rebecca Christine Knickmeyer, Marsha L. Davenport and Bonnie Auyeung
| Assessing prenatal and neonatal gonadal steroid exposure for studies of human development [[electronic resource] ] : methodological and theoretical challenges / / edited by Rebecca Christine Knickmeyer, Marsha L. Davenport and Bonnie Auyeung |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 online resource (80 pages) : illustrations; digital, PDF file(s) |
| Collana | Frontiers Research Topics. |
| Soggetto topico | Endocrinology |
| Soggetto non controllato |
minipuberty
Testosterone androgen receptor digit ratio prenatal sexual differentiation umbilical cord blood Opposite-sex twins Saliva Hypogonadism |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137098403321 |
| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Natural Products from the Red Sea
| Bioactive Natural Products from the Red Sea |
| Autore | Rateb Mostafa |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (152 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
Aspergillus falconensis
OSMAC azaphilones X-ray diffraction NF-κB inhibition LC-HRESIMS Stylissa carteri ceramide cerebroside docking cytotoxic activity co-cultivation phenazine sponge-associated actinomycetes antibacterial antibiofilm DNA gyrase pyruvate kinase ergosterol derivative metabolic analysis docking studies seagrass Thalassodendron ciliatum Red Sea sponges marine actinomycetes Streptomyces coelicolor LY001 halogenated 3-phenylpropanoic acid derivatives diketopiperazine alkaloids structural determinations antimicrobial activities Red Sea marine natural products marine organisms biodiversity marine metagenomics bioactivity Sinularia polydactyla soft coral steroids cytotoxic anti-inflammatory neuroprotective androgen receptor Actinokineospora Rhodococcus co-culture metabolomics antimalarial epicotripeptin phragamide Epicoccum Alternaria antimicrobial |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557540903321 |
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Rateb Mostafa
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination
| Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination |
| Autore | Alix-Panabieres Catherine |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (366 p.) |
| Soggetto non controllato |
FOLFIRINOX
immunofluorescence imaging AR-V7 circulating tumour cells chemoradioresistance CTC-based treatment decisions rVAR2 immunophenotyping immune system CellSearch® flow cytometry clinical trials circulating tumor DNA synaptophysin stem cells colorectal cancer melanoma CTC biology platelets AR CTC capture technology castration resistant prostate cancer (CRPC) PD-L1 expression rovalpituzumab tesirine HMB-45 thymidylate synthase ctDNA tumor cell dissemination solid cancers metastasis locally advanced rectal cancer miRNA epithelial-to-mesenchymal transition (EMT) NSCLC tumor biomarkers tumor stem cells circulating tumor cells major histocompatibility complex class I (MHCI) bone marrow heterogeneity cerebrospinal liquid biopsy fish glioma in vivo flow cytometry colorectal surgery CellSearch single-cell analysis disseminated tumor cells EasyCount slides microsatellite instability circulating plasma cells circulating leukemia cells ARV7 SLUG androgen receptor metastatic colorectal cancer leukocyte-derived extracellular vesicles prostate cancer (PCa) neutrophils liquid biopsy enzalutamide CD133 enrichment and detection technologies biomarkers immune checkpoint inhibitors biomarker RAD23B microbiome integrin B1 ACCEPT emboli small-cell lung carcinoma EPISPOT microfluidics early breast cancer circulating tumor cells (CTC) tumor-initiating cells (TICs) immunomodulation xenograft models CTC-derived xenografts malaria circulating tumor cells (CTCs) clinical utility exosomes liquid surgery ctRNA CTCs epithelial-mesenchymal transition targeted therapy hematological cells gene expression analysis hepatocellular carcinoma (HCC) breast cancer EpCAM enrichment prostate cancer CTC abiraterone fibronectin CTC-derived ex vivo models CTMat chromogranin A CTM exosome |
| ISBN | 3-03928-699-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Circulating Tumor Cells |
| Record Nr. | UNINA-9910404091403321 |
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Alix-Panabieres Catherine
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications
| Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications |
| Autore | Ishii Kenichiro |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
androgen receptor
docetaxel cabazitaxel castration-resistant prostate cancer chemotherapy P-glycoprotein EPI-002 splice variant prostate-specific antigen androgen deprivation therapy time to PSA nadir fibroblasts prostate cancer androgen sensitivity pirfenidone TGFβ1 G1 cell cycle arrest fibroblast growth factor fibroblast growth factor receptor obesity inflammation immune cells cytokine high-fat diet KIFC1 docetaxel resistance apoptosis CW069 Caveolin-1 TP53-regulated inhibitor of apoptosis 1 tumour stroma tumour microenvironment fibroblast CAF resistance radiotherapy CCL2 CCL22 CCL5 migration LSD1 epigenetics autophagy abiraterone enzalutamide testosterone castration resistant prostate cancer animal model diet fat in vitro in vivo mouse AKR1C3 hormone-naïve prostate cancer immunohistochemistry tissue microarray androgen receptor dependency fibroblast-dependent androgen receptor activation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557116703321 |
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Ishii Kenichiro
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diagnostic, Prognostic and Predictive Biological Markers in Bladder Cancer - Illumination of a Vision 2.0
| Diagnostic, Prognostic and Predictive Biological Markers in Bladder Cancer - Illumination of a Vision 2.0 |
| Autore | Ecke Thorsten |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (240 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Metallothionein
urothelium urothelial cancer cadmium exposure zinc transporter bladder TAGLN F-actin PTEN p53 tumorigenesis proliferation invasion TERT promoter mutations FGFR3 non muscle invasive bladder cancer BCG therapy bladder cancer JAK-STAT pathway combination therapy oncolytic adenovirus virotherapy STAT3/5 inhibitor JAK inhibitor XVir-N-31 bladder cancer detection urinary biomarkers DNA methylation ECRG4 ITIH5 biomarker cancer grade metabolomics MS NMR biomarkers tumor markers prognosis heparanase syndecan-1 heparan sulfate proteoglycans (HSPGs) urothelial carcinoma miRNA quantitative PCR tumor marker voided urine cytology KDM7A histone demethylase TC-E 5002 androgen receptor drug resistance non-invasive detection telomerase somatic mutations TERT promoter region muscle-invasive bladder cancer chemotherapy immunotherapy personalized medicine predictive biomarker survivin BIRC5 macrophage KRT20 ERBB2 MIBC prediction RT-qPCR adjuvant chemotherapy survival |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557142003321 |
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Ecke Thorsten
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sex Hormone Receptor Signals in Human Malignancies
| Sex Hormone Receptor Signals in Human Malignancies |
| Autore | Miyamoto Hiroshi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (152 p.) |
| Soggetto non controllato |
FOXA1
COBRA1 estrogen progesterone receptor negative mutational profiling heterogeneous nuclear ribonucleoprotein K estrogen receptor alpha salivary gland tumors castration-resistant prostate cancer ELK1 fibroblasts androgen receptor melanocytes drug screening and proteomics PI3K pathway NELFB therapeutic targets immunohistochemistry androgen deprivation therapy ovarian cancer estrogen receptor epidermal growth factor receptor ethinylestradiol melanoma breast cancer keratinocytes G-protein coupled estrogen receptor prognosis levonorgestrel ultraviolet radiation sex hormone receptors upper urinary tract urothelial carcinoma CRPC nuclear factor erythroid 2-related factor 2 TP53 |
| ISBN | 3-03921-174-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756503321 |
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Miyamoto Hiroshi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Urological Cancer 2020
| Urological Cancer 2020 |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (334 pages) |
| Soggetto topico |
Research
Biology |
| Soggetto non controllato |
renal cell carcinoma
iron macrophages chelation therapy urothelial carcinoma transcriptome microtubule MAP1B prognosis KLF5 androgen receptor cell proliferation tumorigenesis prostate cancer precision medicine whole genome sequencing optical mapping therapy prostate carcinoma prostate mpMRI machine learning artificial intelligence deep learning neural network angiogenesis angiogenic growth factors antiangiogenic therapy renal tumors prevention α1-adrenoceptor antagonists anoikis vascularity research model oncogenes tumor suppressor genes MR-guided radiotherapy MRgRT stereotactic ablative radiotherapy stereotactic ablative radiation therapy (SABR) renal cell cancer RCC online adaptive [68Ga]Ga-PSMA PET/CT dual-time point imaging delayed imaging biphasic imaging lesion positivity rate CXCL9 PD1 PD-L1 stage T1 NMIBC prostatic neoplasms/mortality prostatic neoplasms/epidemiology SEER Program bladder cancer transurethral resection en-bloc resection CPT1A fatty acids serine androgen response ROS oxidative stress DONSON Downstream Neighbor of SON biomarker metastatic spread diagnosis differential diagnosis histopathology immunohistochemistry stroma signature patient-derived xenografts |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557354903321 |
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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