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A History of Burn Care
| A History of Burn Care |
| Autore | Kamolz Lars P |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (206 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
burn
care antiquity phytotherapy ancient medicine burn therapy enzymatic debridement bromelain NexoBrid™ hyperbaric oxygenation history review burn injury donor area wounds polylactide lactormone oxidative stress reduction analgesia stabilization reduced infection fluid management resuscitation volume transpulmonary thermodilution ultrasound burn resuscitation burn care allotransplantation skin transplantation skin graft skin substitute immuno-compatible skin grafts burn size assessment three-dimensional estimation accuracy medical documentation consequences of inaccurate assessment skin grafting skin substitutes burns autograft dermatome mesh split-thickness xenograft CEA CSS Spray-on-Skin ReCell burn history burn advancement burn research carbon monoxide CO intoxication COHb inhalation injury dressing changes epidermal skin substitute grafting healing time infection rate partial thickness burns porcine xenograft resorbable suprathel synthetic workload |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557370603321 |
Kamolz Lars P
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Flavonoids and Their Disease Prevention and Treatment Potential
| Flavonoids and Their Disease Prevention and Treatment Potential |
| Autore | Rupasinghe H.P. Vasantha |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (346 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
luteolin
apigenin bacoside A bacopaside I vasorelaxation isorhamnetin flavonoid bacterial sepsis toll-like receptor 4 inflammation citrus flavonoids neohesperidin anti-aging activity chronological lifespan synergistic effect clinical trials natural products hyperalgesia allodynia analgesia hypersensitivity cytokines NF-kB defatted pitaya seed extraction phenolic content flavonoid content antioxidant activity response surface methodology flavonoids aglycons glycosides IL-1β TNF-α IL-6 IL-8 pro-inflammatory cytokines Acer okamotoanum afzelin isoquercitrin obesity quercitrin aspirin cancer prevention hydroxybenzoic acids cell cycle CDKs colorectal cancer infectious diseases amoebiasis Mexican oregano bioguided isolation antiprotozoal agents flavones cancer microbiome molecular mechanisms gene and protein regulatory networks macrophages NF-κB IKKβ, inflammatory cytokines apoptosis foods for health tangeretin cancer stem cells Stat3 citrus CD44+/CD24− phytochemicals flavonoids and their derivatives phytomedicine COVID-19 SARS-COV-2 smart nanoparticles non-flavonoids membrane PUFAs profile cell morphology human colon cancer cells cranberry urinary tract infections UTIs uropathogenic Escherichia coli UPEC flavan-3-ols A-type proanthocyanidins phenolic metabolites antiadhesive activity probiotics anthocyanin tobacco-specific nitrosamine carcinogenesis cell proliferation cancer chemoprevention lung cancer chalcones DNA damage anticancer activity canine cancer cell lines angiogenesis in-vivo angiogenesis CAM assay SAR cognition passive avoidance test memory extinction mice microglia neuroprotection black rice cyanidin-3-O-glucoside wood sterols dyslipidemia CVD |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557505903321 |
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Rupasinghe H.P. Vasantha
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery II
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery II |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
thiazole
piperazine tail-clip hot-plate acetic acid-induced writhing test opioid prodynorphin epigenetics transcription human brain morphine dosing behavior locomotor activity tolerance µ-opioid receptor DAMGO SR-17018 buprenorphine nalbuphine kappa opioid receptor agonist pruritis scratching mice TAT-HIV cholestasis chloroquine deoxycholic acid analgesic δ opioid receptor G-protein-biased agonist opioid peptide rubiscolins µ-opioid analgesics angiotensin receptors chronic pain neuropathic pain delta opioid receptor inverse agonist irreversible antagonist non-competitive antagonist molecular pharmacology free fatty acid receptors lipids opioid receptor colitis chemotype high-throughput screen allosteric modulation beta-arrestin molecular dynamics opioid receptors β-amino acids peptide synthesis receptor binding studies functional assay nociceptin/orphanin FQ receptor NOP receptor ligands nociceptin N/OFQ analgesia GPCR HS-731 peripheral opioid agonist binding selectivity molecular docking molecular dynamics simulations fluorescence cross-correlation spectroscopy (FCCS) G protein-coupled receptor (GPCR) serotonin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910576875203321 |
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Spetea Mariana
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (358 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
opioid receptors
neurokinin-1 receptor peptide synthesis receptor binding studies functional assay writhing test tolerance Leu-enkephalin beta-arrestin mu opioid receptor delta opioid receptor biased signaling DADLE ischemia plasma stability morphinan BNTX δ opioid receptor antagonist 1H-NMR experiments mechanism elucidation peripheral antinociception 14-methoxycodeine-6-O-sulfate codeine-6-O-sulfate opioid peptides and peptidomimetics DAMGO DALDA [Dmt1]DALDA KGOP01 binding molecular docking structure-activity relationships β2-amino acids β2-Homo-amino acids µ-opioid receptor opioid peptides TAPP racemic synthesis of β2-amino acids peripheral µ-opioid receptors analgesia peripheral analgesic tolerance dysbiosis opioid bifunctional ligands (−)-N-phenethylnorhydromorphone analogs [35S]GTPgammaS assay forskolin-induced cAMP accumulation assays β-arrestin recruitment assays MOR and DOR agonists respiratory depression bias factor molecular modeling & simulation δ opioid receptor NTI derivative sulfonamide inverse agonist neutral antagonist agonist opioids mu receptor opioid side effects biased agonism partial agonism zerumbone chronic constriction injury (CCI) allodynia hyperalgesia potassium channels over-the-counter drugs misuse abuse opioid drugs pharmacology codeine dihydrocodeine loperamide opioid peptide macrocyclic tetrapeptide multifunctional ligands kappa opioid receptor analgesics opioid liabilities μ opioid receptor receptor model biased ligands dependence pain therapy neonatal opioid withdrawal syndrome naltrexone 6β-naltrexol buprenorphine G-protein bias arrestin recruitment respiration mitragynine heteromer internalization primary hippocampal culture lysosomes µ opioid receptor molecular dynamics docking interaction fingerprints biased agonists SR-17018 PZM21 morphine fentanyl diphenethylamines design and synthesis partial agonist biased agonist antagonist binding affinity selectivity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910557108003321 |
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Spetea Mariana
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Protective and Detrimental Role of Heme Oxygenase-1
| Protective and Detrimental Role of Heme Oxygenase-1 |
| Autore | Sorrenti Valeria |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (220 p.) |
| Soggetto non controllato |
coronary artery disease
glucocorticoid receptor antigen presentation analgesia chemotherapy locus coeruleus Sirtuin 1 thiol groups Heme Oxygenase-1 Betula etnensis Raf heme oxygenase 1 tolerance heme oxygenase atherosclerosis nitric oxide caloric restriction liver carbon monoxide ER stress heme oxygenase-1 mineralocorticoid receptor Type 1 diabetes mellitus (T1D) Gamma-Glutamyl-Cysteine Ligase (GGCL) angiotensin II bilirubin Heme oxygenase-1 (HO-1) inducers Inducible nitric oxide synthase (iNOS) HO-1 activity inhibitor ferroptosis Myristica fragrans kernels glutathione high-pressure gas apoptosis HO-1 diabetes mellitus Caffeic acid phenethyl ester (CAPE) carotid plaque ischemia-reperfusion injury ANTIGEN presenting cell LPS endoplasmic reticulum stress hemoglobin Pancreatic oxidative damage Colon cancer inflammation reactive oxygen species inflammatory pain paracetamol cardiomyopathy heme oxigenase-1 adipocytes sirtuin 1 peripheral artery disease PGC-1? heme Reactive oxygen species (ROS) metformin GR prostate cancer NF-?B hyperbilirubinemia iron Tet-ON system lung preservation oxidative stress Gunn rats Dimethylarginine dimethylaminohydrolase-1 (DDAH-1) |
| ISBN | 3-03921-807-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367746303321 |
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Sorrenti Valeria
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Refinements to Animal Models for Biomedical Research
| Refinements to Animal Models for Biomedical Research |
| Autore | Musk Gabrielle |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
mouse
blood sample well-being retrobulbar submandibular sublingual functional MRI rat anaesthesia refinement calves disbudding gene transcription cytokines pain meloxicam nCounter guinea pig Cavia porcellus captive bolt humane euthanasia laboratory animal humane killing piglet castration behaviour peri-operative vocalisation nociception neonate anaesthesia analgesia sheep survey preclinical research health nociceptive threshold horse cat dog camel 3R principles transdermal fentanyl patch grimace scores laboratory animals pain assessment rabbit postoperative analgesia facial expressions grimace scales mice rat animal research animal testing biomedical research history of science |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557128603321 |
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Musk Gabrielle
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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