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Amide Bond Activation / Michal Szostak
| Amide Bond Activation / Michal Szostak |
| Autore | Szostak Michał |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (466 p.) |
| Soggetto topico | Chemistry |
| Soggetto non controllato |
N-heterocyclic carbene
non planar amide ruthenium (Ru) physical organic chemistry gemcitabine prodrug pyramidal amides bridged sultams catalysis dipeptides N-(1-naphthyl)acetamide C-N ? bond cleavage steric effects peptide bond cleavage transition-metal-free palladium N-heterocyclic carbenes (NHCs) addition reaction C–O activation rhodium metal complexes carbanions thioamidation amide bond intramolecular catalysis antiviral activity additivity principle pre-catalysts C–N bond cleavage bridged lactams C–H acidity arynes twisted amides organic synthesis amination Suzuki-Miyaura tert-butyl cyclopentadienyl complexes C-S formation enzymes DFT study sulfonamide bond N HERON reaction primaquine entropy amide activation amidation synthesis amide hydrolysis carbonylicity amide bond activation amide bond resonance aminosulfonylation molecular dynamics model compound in situ amide homogeneous catalysis heterocycles anomeric effect multi-component coupling reaction kinetic excited state C–H bond cleavage palladium catalysis amides thiourea formylation alkynes cis/trans isomerization amide C–N bond activation intein C-H functionalization succindiamide amide bonds crown ether aminoacylation directing groups cytostatic activity reaction thermodynamics acyl transfer transition metals N-dimethylformamide DMAc acylative cross-coupling C-H/C-N activation nickel catalysis antibacterial screening sodium aryl thioamides Winkler-Dunitz parameters catalyst N-dimethylacetamide base-catalyed hydrolysis nitrogen heterocycles cross-coupling insertion amidicity nitro-aci tautomerism activation carbonylation transamidation amine distortion Pd-catalysis rotational barrier energy hypersensitivity N–C activation metabolic stability [2+2+2] annulation twisted amide protease cyanation amide resonance trialkylborane catalysts biofilm eradication pharmacokinetics pancreatic cancer cells DMF aryl esters Michael acceptor fumardiamide water solvation ester bond activation cyclization nuclear magnetic resonance secondary amides reaction mechanism density functional theory density-functional theory amino acid transporters |
| ISBN |
9783039212040
3039212044 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346843703321 |
Szostak Michał
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Therapeutic Potential of Plant Secondary Metabolites in the Treatment of Diseases and Drug Development
| Therapeutic Potential of Plant Secondary Metabolites in the Treatment of Diseases and Drug Development |
| Autore | Drašar Pavel B |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (334 p.) |
| Soggetto topico |
Industrial chemistry and chemical engineering
Technology: general issues |
| Soggetto non controllato |
alkaloids
amide bond anabolic anti-HIV activity antimicrobial activity antiviral therapy artemisinin betulinic acid bevirimat bioavailability BODIPY cancer cancer cells cannabichromene cannabidiol (CBD) cannabinoid receptors (CB1 and CB2) cannabinoids Cannabis sativa (Cannabis) capsaicinoids cardiometabolic diseases cell-cycle chloroquine COVID-19 curcumin curcumin analogues curcumin delivery systems curcumin derivatives cytotoxicity diabetes Duchenne muscular dystrophy ecdysteroid ecdysterone EGFR endocannabinoidome fluorescent microscopy food intake Huisgen 1,3-dipolar cycloaddition inflammation ivermectin lignans lipid accumulation lipidomics lipogenesis lung cancer LXRα MAFLD malaria Mas1 maturation inhibitor membrane fusion metabolism microbiota MMP2 molecular ribbon moxidectin multifunctional PEG3 derivative n/a natural product natural product synthesis natural remedy NF-κB inhibition NSCLC obesity onchocerciasis osteoporosis overweight Papaver somniferum (opium poppy) PD-L1 phytocannabinoids phytochemical quinine respiratory diseases sarcopenia SARS-CoV-2 secondary metabolites STAT3 supramolecular self-assembly tanshinone IIA tetrahydrocannabinol (THC) thermos-TRPs triterpenoid TRPA1 tumorsphere United States Food and Drug Administration-approved drug ursolic acid vinblastine vincristine viral fusion inhibitor α,α-dimethylheptyl effect β-ecdysone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580203103321 |
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Drašar Pavel B
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||