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Hallmarks of Parkinson’s Disease
| Hallmarks of Parkinson’s Disease |
| Autore | Alves Da Costa Cristine |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (124 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
Parkinson’s disease
unfolded protein response reticulum endoplasmic genetics alpha-synuclein prion-like spreading cell-to-cell transfer neurodegeneration mitochondrial dysfunction PINK1 neurons astrocytes microglia α-synuclein exocytosis lipids membranes Parkinson disease SNARE complex synapse vesicle fusion therapeutic target protein quality control mitochondrial quality control ubiquitin alpha-syn mitophagy Parkin mito-Keima mito-QC mito-SRAI |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069503321 |
Alves Da Costa Cristine
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Psychiatry
| Molecular Psychiatry |
| Autore | Rein Theo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Mental health services |
| Soggetto non controllato |
cardiovascular disease
cell adhesion molecules immunology inflammation nervous system schizophrenia bipolar disorder major depressive disorder DNA methylation response variability antipsychotics drug design multi-target drugs polypharmacology multi-task learning machine learning biomarker discovery psychiatry serotonin 5-HT 4 receptor 5-HT4R depression mood disorder expression Alzheimer's disease cognition Parkinson's disease forced swimming Roman rat lines stress hippocampus BDNF trkB PSA-NCAM western blot immunohistochemistry general cognitive function intelligence GWAS genetic correlation childhood-onset schizophrenia (COS) induced pluripotent stem cell (iPSC) copy number variation (CNV) early neurodevelopment neuronal differentiation synapse dendritic arborization miRNAs stress physiology cytoskeleton actin dynamics DRR1 TU3A FAM107A acid sphingomyelinase alcohol dependence liver enzymes sphingolipid metabolism withdrawal Hsp90 GR stress response steroid hormones molecular chaperones psychiatric disease circadian rhythms FKBP51 FKBP52 CyP40 PP5 DISC1 neurodevelopment CRMP-2 proteomics antidepressant treatment HPA axis gene expression FKBP5 sleep sleep EEG biomarkers antidepressants cordance gender sex difference antidepressant rapid-acting Ketamine endocrinology (2R,6R)-Hydroxynorketamine electroconvulsive therapy basic-helix-loop-helix brain coactivator glucocorticoids mineralocorticoid receptor knockout transcription biology dopaminergic gene polymorphisms affective temperament obesity alpha-synuclein SNCA major depression Hamilton Scale of Depression chemokines neuroinflammation social defeat Immune response T cells susceptibility resilience Treg cells Th17 cells behavior PPARγ |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557793503321 |
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Rein Theo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neurogenic Bowel Dysfunction
| Neurogenic Bowel Dysfunction |
| Autore | Krogh Klaus |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (242 p.) |
| Soggetto topico |
Medicine
Neurology & clinical neurophysiology |
| Soggetto non controllato |
laxatives
constipation adults prevalence utilisation gut microbiota spina bifida transanal irrigation urinary tract infection SCI MENTOR NBD fecal incontinence Parkinson’s disease autonomic gastrointestinal alpha-synuclein parasympathetic neurogenic bowel dysfunction low anterior resection syndrome faecal incontinence chronic constipation bowel dysfunction quality of life spinal cord injury multiple sclerosis pharmacological systematic review neurogenic bowel treatment assessment bowel function exoskeletal walking difficulty with evacuation neostigmine glycopyrrolate iontophoresis autonomic dysfunction motility investigations manometry breath test imaging diabetes mellitus postprandial hypotension food ingestion ambulatory blood pressure measurement cohort study pediatric children adolescent anorectal malformation cerebral palsy acute rehabilitation opioids SCI bowel management |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585944903321 |
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Krogh Klaus
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutrition for Brain Development
| Nutrition for Brain Development |
| Autore | Mohajeri M. Hasan |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (262 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
cocaine self-administration
high-fat diet high-sugar diet maternal diet pregnancy and lactation melanocortin-4 receptor offspring brain rat offspring maternal nutrition protein restriction fetal brain hypothalamus differentiation neurogenesis transcriptomics epitranscriptomics mitochondria PKU cognitive outcomes cross-cultural cross-countries Phe associations spearmint rosmarinic acid polyphenol amyloid fibril amyloid beta alpha-synuclein Tau dementia human milk oligosaccharides cognition brain development animal behaviour fucosyllactose sialyllactose long term potentiation gut-brain-axis gut microbiome short-chain fatty acids bacterial metabolites SCFA manganese blood-brain barrier blood-cerebrospinal fluid barrier choroid plexus ketogenic supplement ketosis aging lifespan neurodegenerative disease learning memory early childhood nutrition Mediterranean diet body mass index cognitive development multi-omics microvascular brain high glycemic diet soluble epoxide hydrolase inhibitor maless depression affective disorder bacteria probiotics therapy treatment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566471203321 |
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Mohajeri M. Hasan
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Protein Adsorption and Conformational Changes
| Protein Adsorption and Conformational Changes |
| Autore | Assfalg Michael |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (100 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
sarcoplasmic reticulum Ca2+-ATPase
Cu+-ATPase phospholipid flippase charge displacement concentration jump solid supported membrane conformational transition electrogenicity ion translocation phospholipid flipping protein-nanoparticle interactions protein NMR amyloidogenic proteins nitroxide paramagnetic perturbation spin label extrinsic probes Tempol β2-microglobulin protein conformation protein-surface association lipid membranes surface-immobilized protein EPR spectroscopy alpha-synuclein amyloid fibrils conformational flexibility protein adsorption protein aggregation nano-bio interface nanocomposite nanoparticles supramolecular assembly NMR spectroscopy gold nanoparticles PEGylation adsorption passivation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566466103321 |
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Assfalg Michael
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances in Nutritional Psychiatry
| Recent Advances in Nutritional Psychiatry |
| Autore | Grosso Giuseppe |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (168 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
polyphenol
sleep mental health cohort antioxidant cognitive brain Sicily population diet quality nutrition depression mood disorders prevention food insecurity sleep disturbance adults cross-sectional study dietary pattern gestation diet sleep quality Pittsburgh sleep quality index GABA ketogenic diet low-carbohydrate anxiety ketosis gut microbiota nutritional psychiatry bioflavonoids functional food neurodegeneration T-maze Barnes test passive avoidance animal models alpha-synuclein neuroinflammation Passiflora incarnata neuropsychiatric disorders stress depressive disorder mental disorders nutrition surveys trends time restricted feeding intermittent fasting chrononutrition brain diseases aging risk factor Mediterranean diet coffee consumption caffeine cerebrovascular disease executive dysfunction geriatric depression dose-response association dietary factors lifestyle mood |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557617903321 |
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Grosso Giuseppe
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Studies of Rodent Ultrasonic Vocalizations and Their Use in Experimental Models
| Recent Studies of Rodent Ultrasonic Vocalizations and Their Use in Experimental Models |
| Autore | Brudzynski Stefan M |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (352 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
ultrasonic vocalization
maternal immune activation autism communication rat sex differences social play rats anxiety observational fear learning USV maternal separation pup vasopressin antagonists righting reflex negative geotaxis ACTH corticosterone Brattleboro rat larynx female male 50-khz ultrasonic vocalizations (USVs) individual differences chronic variable stress (CVS) dopamine nucleus accumbens microdialysis evolution of vocalization 22 kHz calls 50 kHz calls infant isolation calls emotional arousal mesolimbic dopaminergic system mesolimbic cholinergic system hedonia ultrasonic vocalizations cognitive development respiration brain oscillations Cav1.2 calcium animal model rough-and-tumble play social approach playback social contact call alarm call social buffering distress emotional contagion fear contagion aversive state automated scoring addiction mental health machine learning drug discovery drug development Parkinson's disease alpha-synuclein 6-OHDA Pink1 DJ1 exercise pharmacology pathology hypervigilance hyperreactivity exaggerated reactivity generalization PTSD depression heart rate Wistar 22-kHz calls 50-kHz calls affect aversion NOR reward working memory Y maze opioids fentanyl self-administration play food dam-pup interaction ethanol pup isolation rat pup 50 kHz vocalizations 22 kHz vocalizations amphetamine chemogenetics clozapine-n-oxide UMAP males females vocalizations fear extinction pain |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557608903321 |
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Brudzynski Stefan M
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Amazing World of IDPs in Human Diseases
| The Amazing World of IDPs in Human Diseases |
| Autore | Monti Simona Maria |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
alpha-synuclein
NMR secondary structure propensity pre-structured motifs (PreSMos) intrinsically disordered protein ubiquitin-proteasome system intrinsically disordered proteins protein misfolding molecular recognition features cancer neurodegenerative diseases protein degradation EPR spectroscopy isothermal titration calorimetry protein-ligand interaction site-directed spin labeling protein structural dynamics WASp interacting protein protein-protein interactions actin cytoskeleton remodeling SH3 domain proline-rich motif single nucleotide variants interface core and rim human disease intrinsically disordered regions linear motifs gene duplications de novo evolutionary origin circular dichroism flexibility fluorescence importin isothermal titration calorimetry (ITC) molecular docking nuclear magnetic resonance (NMR) nuclear protein 1 (NPR1) peptide Methyl-CpG-binding protein 2 (MeCP2) Rett syndrome intrinsically disordered protein (IDP) protein stability protein-DNA interaction proteostasis ubiquitin independent degradation NADH-26S proteasome |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557334303321 |
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Monti Simona Maria
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Molecular and Cellular Basis for Parkinson's Disease
| The Molecular and Cellular Basis for Parkinson's Disease |
| Autore | Müller Thomas |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto non controllato |
microRNAs
disease-modifying effects SH-SY5Y inpatient treatment sphingolipids neurodegeneration magnetic resonance spectroscopy MO3.13 schizophrenia epigenetics long-chain acylcarnitine molecular mimicry curli multimodal complex treatment chlorogenic acid glycerophospholipids caffeic acid lipoproteins myenteric plexus neurometabolites HOG immature oligodendrocyte autophagy oligodendrocyte hypochlorite alpha-synuclein microbiome glucocerebrosidase Lewy Body Dementia brain iron mesenchymal stem cells fatty acid ?-oxidation GABA enteric glial cell gut-brain axis microbiota REM sleep behavior disorders redox cycling magnetic resonance imaging differentiation ?-synuclein-mediated pathology Parkinson disease Gaucher’s disease metallothionein [123I]FP-CIT-SPECT dopaminergic neuron mature oligodendrocyte glycerolipids spectroscopy neuroinflammation exosomes immunotherapy DNA methylation sterol lipids nigral cells cell line cysteinyl-dopamine myelin parkinsonisms multiple sclerosis rotenone brain fatty acyls Krabbe’s disease neuroprotection DAT motor dysfunction secretome multiprofessional therapy Parkinson’s disease oxidative stress alpha-Synuclein |
| ISBN | 3-03921-549-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367753003321 |
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Müller Thomas
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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