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A Themed Issue in Honor of Professor Raphael Mechoulam: The Father of Cannabinoid and Endocannabinoid Research
| A Themed Issue in Honor of Professor Raphael Mechoulam: The Father of Cannabinoid and Endocannabinoid Research |
| Autore | Maccarrone Mauro |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (236 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research and information: general |
| Soggetto non controllato |
4'-fluoro-cannabidiol
6-hydroxydopamine alcohol craving allodynia aminoalkylindole amyotrophic lateral sclerosis anandamide anti-CB1 antibody anti-inflammatory antinociception biased signaling cannabichromene cannabidiolic acid cannabidivarin cannabidivarinic acid cannabigerol cannabinoid cannabinoid receptor cannabinoid receptor 2 (CB2R) cannabinoid tetrad cannabinoids catalepsy CB1 CB1 receptor antagonist cholesterol chromenopyrazole CP55940 drinking in the dark elevated plus maze endocannabinoid equilibrative nucleoside transporter frontal cortex functional selectivity G-protein ghrelin GPR55 receptors gut microbiome hippocampus HUF-101 hybrid ligand inflammaging iNOS inhibitor intestine intracerebroventricular administration JWH-018 K2 LEAP2 lipofuscin lipopolysaccharide marble bury memory microglia MRI-1867 mSOD1 mice N-acyltransferase n/a obesity Parkinson's disease phospholipase A2 phytocannabinoids PPARs pravadoline rescue model rimonabant spice synaptosomes TDP-43 transgenic mice tetrahydrocannabivarin two-bottle paradigm type 1 cannabinoid receptor CB1 VCE-006.1 WIN55212-2 β-arrestin |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Themed Issue in Honor of Professor Raphael Mechoulam |
| Record Nr. | UNINA-9910566470103321 |
Maccarrone Mauro
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Botulinum Neurotoxins and Nervous System : Future Challenges for Novel Indications
| Botulinum Neurotoxins and Nervous System : Future Challenges for Novel Indications |
| Autore | Luvisetto Siro |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (368 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
abobotulinumtoxinA
allodynia antipruritic appropriate treatment astroglia basal ganglia biological effect BoNT/A botulinum antitoxin botulinum neurotoxin botulinum neurotoxin serotype A botulinum neurotoxin serotype a heavy chain (BoNT/A HC) botulinum neurotoxin-A botulinum neurotoxins botulinum toxin Botulinum toxin botulinum toxin A botulinum toxin therapy botulinum toxin type A BTX central neuropathic pain cerebral palsy chloroquine chronic pelvic pain clinical clinical decision support clinical trial Clostridium tetani complex regional pain syndrome compound 48/80 delivery dental occlusion dermatology diagnostic guidance drooling dystonic tremor early use eccrine glands electrical activity electrical stimulation electromyography epilepsy essential tremor experimental food safety formulation glia growth associated protein 43 (GAP-43) hand hand tremor heavy chain human immunohistochemistry incobotulinumtoxin A interleukins interneurons interspecies differences in motor behavior itch joint biomechanics kinematics lateral pterygoid muscle limb tremors lumbar sympathetic ganglion block mast cells masticatory system maxillofacial bone medication overuse headache microglia mouse mouse test movement disorders muscle selection n/a nerve regeneration neural regeneration neuronal processes neurotransmission blockade neurotransmitter new indications novel indication onabotulinumtoxin A ONTIME orthognathic surgery overactive detrusor pain Parkinson's disease post-stroke post-stroke shoulder pain prion disease prophylactic treatment pruritus rat refractory chronic migraine rehabilitation salivary glands Schwann cells sciatic static index sialorrhoea Snap-23 SNAP-25 SNARE spastic paresis spasticity spinal cord spinal cord injury spinal cord injury (SCI) stroke management superior cervical ganglion 10 (SCG10) swallowing synaptic transmission temporomandibular joint dislocation tension headache Therapeutic Index TLR2 TLR4 treatment tremor upper limb biomechanics upper limb spasticity urodynamics vaginism VAMP various cell types walking track analysis weight bearing XEOMIN® |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Botulinum Neurotoxins and Nervous System |
| Record Nr. | UNINA-9910557109003321 |
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Luvisetto Siro
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Flavonoids and Their Disease Prevention and Treatment Potential
| Flavonoids and Their Disease Prevention and Treatment Potential |
| Autore | Rupasinghe H.P. Vasantha |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (346 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
A-type proanthocyanidins
Acer okamotoanum afzelin aglycons allodynia amoebiasis analgesia angiogenesis anthocyanin anti-aging activity antiadhesive activity anticancer activity antioxidant activity antiprotozoal agents apigenin apoptosis aspirin bacopaside I bacoside A bacterial sepsis bioguided isolation black rice cyanidin-3-O-glucoside CAM assay cancer cancer chemoprevention cancer prevention cancer stem cells canine cancer cell lines carcinogenesis CD44+/CD24− CDKs cell cycle cell morphology cell proliferation chalcones chronological lifespan citrus citrus flavonoids clinical trials cognition colorectal cancer COVID-19 cranberry CVD cytokines defatted pitaya seed DNA damage dyslipidemia extraction flavan-3-ols flavones flavonoid flavonoid content flavonoids flavonoids and their derivatives foods for health gene and protein regulatory networks glycosides human colon cancer cells hydroxybenzoic acids hyperalgesia hypersensitivity IKKβ, inflammatory cytokines IL-1β IL-6 IL-8 in-vivo angiogenesis infectious diseases inflammation isoquercitrin isorhamnetin lung cancer luteolin macrophages membrane PUFAs profile memory extinction Mexican oregano mice microbiome microglia molecular mechanisms n/a natural products neohesperidin neuroprotection NF-kB NF-κB non-flavonoids obesity passive avoidance test phenolic content phenolic metabolites phytochemicals phytomedicine pro-inflammatory cytokines probiotics quercitrin response surface methodology SAR SARS-COV-2 smart nanoparticles Stat3 synergistic effect tangeretin TNF-α tobacco-specific nitrosamine toll-like receptor 4 UPEC urinary tract infections uropathogenic Escherichia coli UTIs vasorelaxation wood sterols |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557505903321 |
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Rupasinghe H.P. Vasantha
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Matrix Metalloproteinase
| Matrix Metalloproteinase |
| Autore | Ågren Magnus S |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (262 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
a disintegrin and metalloproteinase
ADAM ADAMTS adult aggrecan aggrecanase Agkistrodon venom allodynia anticoagulants antithrombotic apoptosis arthritis blood sampling cancer cartilage caspase-3 CD147 central nervous system chemokine cytokine cytokines diseases dorsal root ganglion ectodomain shedding EMMPRIN extracellular matrix extracellular matrix breakdown fibrinogen gastric cancer glycosaminoglycans glycosylation hemagglutinin-B high-molecular-weight heparin HIV-TB-associated IRIS IL-11 IL-16 IL-6 IL-8 inflammation inhibitor interferon interleukin interstitial collagens invasion lung matrix metalloproteinase matrix metalloproteinases matrix metalloproteinases (MMPs) matrix-metalloproteinase meprin metabolomics metalloproteases metalloproteinase metastatic dissemination MMP MMP-2 MMP-9 MMPs monocytes MT4-MMP neuropathic pain pediatric peritoneal mesothelial cell phagocytosis phosphorylation protease proteinases proteomics PTMs sICAM-1 signaling spinal nerve ligation T cells TNF-α trans-signaling transwell co-cultures tuberculosis tuberculous meningitis wound healing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557717203321 |
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Ågren Magnus S
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (358 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
(−)-N-phenethylnorhydromorphone analogs
[35S]GTPgammaS assay [Dmt1]DALDA 14-methoxycodeine-6-O-sulfate 1H-NMR experiments 6β-naltrexol abuse agonist allodynia analgesia analgesics antagonist arrestin recruitment beta-arrestin bias factor biased agonism biased agonist biased agonists biased ligands biased signaling bifunctional ligands binding binding affinity BNTX buprenorphine chronic constriction injury (CCI) codeine codeine-6-O-sulfate DADLE DALDA DAMGO delta opioid receptor dependence design and synthesis dihydrocodeine diphenethylamines docking dysbiosis fentanyl forskolin-induced cAMP accumulation assays functional assay G-protein bias heteromer hyperalgesia interaction fingerprints internalization inverse agonist ischemia kappa opioid receptor KGOP01 Leu-enkephalin loperamide lysosomes macrocyclic tetrapeptide mechanism elucidation misuse mitragynine molecular docking molecular dynamics molecular modeling & MOR and DOR agonists morphinan morphine mu opioid receptor mu receptor multifunctional ligands n/a naltrexone neonatal opioid withdrawal syndrome neurokinin-1 receptor neutral antagonist NTI derivative opioid opioid drugs opioid liabilities opioid peptide opioid peptides opioid peptides and peptidomimetics opioid receptors opioid side effects opioids over-the-counter drugs pain therapy partial agonism partial agonist peptide synthesis peripheral analgesic tolerance peripheral antinociception peripheral µ-opioid receptors pharmacology plasma stability potassium channels primary hippocampal culture PZM21 racemic synthesis of β2-amino acids receptor binding studies receptor model respiration respiratory depression selectivity simulation SR-17018 structure-activity relationships sulfonamide TAPP tolerance writhing test zerumbone β-arrestin recruitment assays β2-amino acids β2-Homo-amino acids δ opioid receptor δ opioid receptor antagonist μ opioid receptor µ opioid receptor µ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910557108003321 |
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Spetea Mariana
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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