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Epigenetics [[electronic resource] ] : linking genotype and phenotype in development and evolution / / edited by Benedikt Hallgrímsson and Brian K. Hall
| Epigenetics [[electronic resource] ] : linking genotype and phenotype in development and evolution / / edited by Benedikt Hallgrímsson and Brian K. Hall |
| Autore | Hallgrímsson Benedikt |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Berkeley, : University of California Press, c2011 |
| Descrizione fisica | 1 online resource (469 p.) |
| Disciplina | 576.5/3 |
| Altri autori (Persone) |
HallgrímssonBenedikt
HallBrian Keith <1941-> |
| Soggetto topico |
Phenotype
Epigenesis Genotype-environment interaction Genetic regulation Developmental genetics Evolutionary genetics |
| Soggetto non controllato |
adaptation
allele asymmetry biological systems biology bone morphology brain cardiac neural crest cell differentiation chromatin developmental biology disease dysmorphology epigenetics evolution evolutionary biology genetic assimilation genetic traits genetics genotype healthcare life sciences mandible medicine morphogenesis nonfiction organ formation phenotype science technology tooth development waddington |
| ISBN |
1-283-33185-3
9786613331854 0-520-94882-3 |
| Classificazione | WG 1940 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Frontmatter -- Contents -- Contributors -- 1. Introduction -- 2. A Brief History of the Term and Concept Epigenetics -- 3. Heuristic Reductionism and the Relative significance of Epigenetic Inheritance in evolution -- 4. The Epigenetics of Genomic Imprinting: Core Epigenetic Processes are conserved in Mammals, Insects, and Plants -- 5. Methylation Mapping in Humans -- 6. Asexuality and Epigenetic Variation -- 7. Epigenesis, Preformation, and the Humpty Dumpty Problem -- 8. A Principle of Developmental Inertia -- 9. The Role of Epigenetics in Nervous System Development -- 10. Morphogenesis of Pigment Patterns: Experimental and Modeling Approaches -- 11. Epigenetic Interactions of the Cardiac Neural Crest -- 12. Epigenetics in Bone and cartilage Development -- 13. Muscle-Bone Interactions and the Development of skeletal Phenotype: Jaw muscles and the skull -- 14. Evolution of the Apical Ectoderm in the Developing Vertebrate Limb -- 15. Role of Skeletal Muscle in the Epigenetic Shaping of Organs, Tissues, and Cell Fate Choices -- 16. Epigenetic Integration, Complexity, and Evolvability of the Head: Rethinking the Functional Matrix Hypothesis -- 17. Epigenetic Interactions: The Developmental Route to Functional Integration -- 18. Epigenetic Contributions to Adaptive Radiation: Insights from Threespine Stickleback -- 19. Learning, Developmental Plasticity, and the Rate of Morphological Evolution -- 20. Epigenetics: Adaptation or Contingency? -- 21. The Epigenetics of Dysmorphology. Craniosynostosis as an Example -- 22. Epigenetics of Human Disease -- 23. Epigenetics: The Context of Development -- Index |
| Record Nr. | UNINA-9910791806903321 |
Hallgrímsson Benedikt
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| Berkeley, : University of California Press, c2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacogenetics to Avoid Adverse Drug Reactions
| Pharmacogenetics to Avoid Adverse Drug Reactions |
| Autore | López-Fernández Luis A |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (220 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
5-fluorouracil
capecitabine fluoropyrimidine thymidylate synthase thymidylate synthase enhancer region upstream stimulatory factor 1 adverse drug reactions pharmacogenomics epistasis random forest statin cardiovascular disease colorectal cancer personalised medicine toxicity (es)citalopram drug-gene-interaction drug-drug-interaction drug-drug-gene-interaction the PharmLines initiative antipsychotic agents pharmacogenetics cytochrome P-450 enzyme system psychotic disorders precision medicine direct oral anticoagulants clinical implementation atorvastatin SLCO1B1 HLA cutaneous adverse drug reaction SCAR genetic polymorphism antiepileptics CYP450 enzymes platelet reactivity single-nucleotide variants acute coronary syndrome clopidogrel genotype allele polymorphism HLA B CYP2C9*3 cutaneous adverse drug reactions (CADRs) anti-epileptic drugs (AEDS) phenytoin (PHT) genetic risk factors South India India cardiology adverse events guidelines |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557610103321 |
|
López-Fernández Luis A
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||