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From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential
| From a Molecule to a Drug: Chemical Features Enhancing Pharmacological Potential |
| Autore | Ribaudo Giovanni |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
SARS-CoV-2
benzoic acid derivatives gallic acid molecular docking reactivity parameters selenoxide elimination one-pot imine-enamine reaction mechanism DFT calculations selenium anti-inflammatory drugs QSAR pain management cyclooxygenase multitarget drug cannabinoid neuropathic pain clopidogrel NMR study oxone peroxymonosulfate sodium halide thienopyridine drug discovery precision medicine pharmacodynamics pharmacokinetics coronavirus SARS-CoV-2 COVID-19 3-chymotrypsin-like protease pyrimidonic pharmaceuticals molecular dynamics simulations binding free energy β-carrageenan antioxidant activity Box-Behken extraction Eucheuma gelatinae physic-chemistry rheology quercetin quercetin 3-O-glucuronide cisplatin nephrotoxicity cytoprotection lithium therapy neurocytology toxicology neuroprotection chemoinformatics big data methadone hydrochloride pharmaceutical solutions drug compounding high performance liquid chromatography stability study microbiology fucoidan alginate L-selectin E-selectin MCP-1 ICAM-1 THP-1 macrophage monocyte migration protein binding breast milk M/P ratio statistical modeling molecular descriptors chromatographic descriptors affinity chromatography anti-ACE anti-DPP-IV gastrointestinal digestion in silico molecular dynamics paramyosin seafood target fishing |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | From a Molecule to a Drug |
| Record Nr. | UNINA-9910585940503321 |
Ribaudo Giovanni
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Looking Forward to the Future of Heparin: New Sources, Developments and Applications
| Looking Forward to the Future of Heparin: New Sources, Developments and Applications |
| Autore | Fareed Jawed |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2018 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto non controllato |
alginate
edema Heparin Red solid lipid nanoparticles Fe3O4·DA-BSA/HA dermatan sulfate sulfated alginate porcine heparin theranostics low-molecular-weight heparin Arixtra® biomaterials hepcidin ovarian cancer iron oxide nanoparticles heparin-induced thrombocytopenia bone morphogenetic protein (BMP) hyaluronic acid (HA) crude heparin platelets resistance sclerostin LMWH gremlin low molecular weight heparin (LMWH) low molecular weight glycosaminoglycans human plasma single crystal X-ray structure iron homeostasis noggin super paramagnetic iron oxide nanoparticles (SPION) manufacturing methods paclitaxel (PTX) brain injury bovine heparin inflammation qNMR antithrombin reference standard quantitative NMR enoxaparin danaparoid sodium NMR GDNF orthogonal multi-analytical methods ternary complex heparan sulphate serglycin bovine serum albumin (BSA) HSQC recombinant expression heparin heparin oligosaccharides functional assay BMP antagonists intestinal lymphatic absorption size exclusion chromatography heparin coating diagnosis bioreactor anemia proteoglycan heparin process PCA chemometric fluorescent probe pharmacopeia affinity chromatography component quantitative analysis Fondaparinux sodium perylene diimide dyes thrombin inhibition extended physicochemical characterization cisplatin glycosaminoglycans TGF-? chondroitin sulfate dalteparin sequence and compositional investigations molecular weight magnetic resonance imaging (MRI) industrial LC-MS iduronic acid conformation heparan sulfate growth and differentiation factor (GDF) assay subarachnoid hemorrhage |
| ISBN | 3-03842-950-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Looking Forward to the Future of Heparin |
| Record Nr. | UNINA-9910346841803321 |
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Fareed Jawed
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| MDPI - Multidisciplinary Digital Publishing Institute, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Proteomic Research 2.0
| Plant Proteomic Research 2.0 |
| Autore | Komatsu Setsuko |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto non controllato |
14-3-3 proteins
targeted two-dimensional electrophoresis somatic embryogenesis nitrogen metabolism subtilase Sporisorium scitamineum non-orthodox seed antioxidant activity sweet potato plants infected by SPFMV photosynthesis B. acuminata petals chlorophyll deficiency seed proteomics imbibition pollination Sarpo Mira qRT-PCR holm oak tuber phosphoproteome isobaric tags for relative and absolute quantitation (iTRAQ) Quercus ilex nucleotide pyrophosphatase/phosphodiesterase lettuce ?-subunit protein phosphatase germination drought stress pyruvate biosynthesis weakening of carbon metabolism differential proteins heterotrimeric G protein organ LC-MS-based proteomics potato proteomics smut gel-free/label-free proteomics ? subunit shotgun proteomics 2D chloroplast proteome functional annotation Phalaenopsis Clematis terniflora DC wheat Dn1-1 carbon metabolism physiological responses Zea mays phenylpropanoid biosynthesis ISR mass spectrometric analysis patatin leaf pea (Pisum sativum L.) maize ergosterol Camellia sinensis seed storage proteins silver nanoparticles elevated CO2 metacaspase SPV2 and SPVG SnRK1 MALDI-TOF/TOF (phospho)-proteomics leaf spot rice isogenic line wheat leaf rust pathway analysis phosphoproteome sugarcane senescence Oryza sativa L. Arabidopsis thaliana heat stress gene ontology innate immunity Pseudomonas syringae bolting chlorophylls shoot Simmondsia chinensis RT-qPCR stresses responses Solanum tuberosum seeds GC-TOF-MS sucrose proteome Puccinia recondita cultivar Zea mays L. secondary metabolism ROS Ricinus communis L. after-ripening cadmium Stagonospora nodorum virus induced gene silencing quantitative proteomics sweet potato plants non-infected by SPFMV affinity chromatography population variability GS3 fungal perception ammonium transcriptome profiling mass spectrometry analysis papain-like cysteine protease (PLCP) cold stress nitrate late blight disease early and late disease stages seed imbibition lesion mimic mutant protease proteome map seed dormancy petal 2-DE proteomics 2D DIGE root Phytophthora infestans differentially abundant proteins (DAPs) polyphenol oxidase degradome flavonoid 14-3-3 caspase-like proteomics RGG4 co-infection plasma membrane chlorotic mutation Medicago sativa RGG3 glycolysis barley 2-DE protein phosphorylation western blotting N utilization efficiency rice plant pathogenesis responses high temperature data-independent acquisition pattern recognition receptors vegetative storage proteins leaf cell wall proteome plant-derived smoke iTRAQ starch proteome profiling Morus |
| ISBN | 3-03921-063-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346666103321 |
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Komatsu Setsuko
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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