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Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy : Future Perspectives
| Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy : Future Perspectives |
| Autore | Vermehren Charlotte |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (224 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
acute kidney injury
early biomarker plasma neutrophil gelatinase-associated lipocalin soluble urokinase plasminogen activator receptor medication optimization older patients emergency department multimorbidity polypharmacy potentially inappropriate medication use older adults prevalence determinants chronic outpatient 2019 Beers criteria Ethiopia pharmacogenomics persons with diabetes drug–drug interactions drug–gene interactions cytochrome P450 SLCO1B1 drug interaction checkers adverse drug reactions pharmacogenetics personalized medicine phenprocoumon DOACs bleeding thromboembolism HLA drug hypersensitivity abacavir allopurinol flucloxacillin antiepileptic drugs cost-effectiveness shared medication record medication reconciliation drug information service hospital pharmacy service electronic prescribing electronic medical record clinical pharmacist CYP2D6 CYP2D7P CYP2D8P copy number variation CNV genotyping 5’nuclease assay HRM high resolution melting drug metabolization extracellular vesicles exosomes microvesicles pharmacogene expression medication review deprescriptions quality of life aged aged, 80 and over nursing homes deprescribing medication-based risk score health outcomes cytochromes CYP1A2 adverse drug reaction antipsychotics olanzapine clozapine loxapine children youth digital decision-support health services research general practice process evaluation antidepressants utility population-based appropriateness medication adherence digital health |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy |
| Record Nr. | UNINA-9910595072903321 |
Vermehren Charlotte
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug-Drug Interactions
| Drug-Drug Interactions |
| Autore | Kim Dong Hyun |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (242 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
tadalafil
ticagrelor drug-drug interaction pharmacokinetics plasma concentration CYP3A4 Loxoprofen CYP3A Dexamethasone Ketoconazole CYP2D6 O-desmethyltramadol physiologically-based pharmacokinetics tramadol (‒)-sophoranone CYP2C9 potent inhibition in vitro in vivo drug interaction low permeability high plasma protein binding biflavonoid cytochrome P450 drug interactions selamariscina A uridine 5′-diphosphoglucuronosyl transferase tissue-specific systemic exposure P-glycoprotein (P-gp) organic anion transporting polypeptide 1A2 (OATP1A2) Rumex acetosa fexofenadine chronic kidney disease drug–drug interactions polypharmacy adverse drug reactions Lexicomp subset analysis signal detection algorithms spontaneous reporting systems mechanism-based inhibition competitive inhibition non-competitive inhibition substrate inhibitor cytochromes P450 OATP1B1 OATP1B3 tyrosine kinase inhibitors drug-drug interactions migraine lasmiditan gepants monoclonal antibodies CYP1A1 CYP1A2 drug–drug interaction expression metabolism regulation drug transporter ubiquitination ixazomib DDI computational prediction in silico QSAR drug metabolism ADME CYP metabolic DDI P450 1A2 2B6 2C19 2C8 2C9 2D6 3A4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557666403321 |
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Kim Dong Hyun
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Innovation and Evidence for Achieving TB Elimination in the Asia-Pacific Region
| Innovation and Evidence for Achieving TB Elimination in the Asia-Pacific Region |
| Autore | DuCros Philipp |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
pediatric TB
verbal screening contact tracing resources sputum health promotion operational research indigenous population multidrug-resistant tuberculosis household contact screening TB diagnosis yield operations research contacts contact investigation MDR-TB public-private mix model public-private partnership missing cases SORT IT TB diagnostics laboratory methods case detection Xpert Ultra STR Bangladesh regimen tuberculosis post-tuberculosis morbidity and mortality TB preventive therapy latent TB infection Asia Pacific rifapentine-isoniazid incidence household contacts tracing End TB sustainable development goals South-East Asia Western Pacific Region national TB program socio-economic determinants diabetes mellitus TB-DM adverse drug reactions unfavourable outcome lymph node TB bone TB TB elimination extrapulmonary tuberculosis private sector intermediary agency referral notification Viet Nam active case finding community outreach Indonesia key population innovation TB REACH community health workers mobile X-ray screening TB chest X-ray active TB case-finding diagnostic algorithm |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557609703321 |
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DuCros Philipp
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Macular Edema: The Current Recommendations for Clinical Practice
| Macular Edema: The Current Recommendations for Clinical Practice |
| Autore | Maciej Gawęcki |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (128 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
angiogenesis
angiopoietin-1 central serous chorioretinopathy proangiogenic factors combined treatment subthreshold diode micropulse anti-VEGF treatment diabetic macular edema retinal vein occlusion Coats disease peripheral retinal telangiectasia laser photocoagulation hypotony maculopathy complications of antiglaucoma surgery bleb compressive sutures age-related macular degeneration AMD proteomics tear film tear film proteome protein clearance neovascularization neovascular AMD macular edema uveitis uveitic complications non-steroidal anti-inflammatory drugs steroids biologic treatment Irvine–Gass syndrome cystoid macular edema pseudophakic cystoid macular edema NSAIDs corticosteroids anti-VEGF intravitreal injections intravitreal agents best corrected visual acuity central retinal thickness adverse drug reactions intravitreal drug expenses |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Macular Edema |
| Record Nr. | UNINA-9910557611003321 |
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Maciej Gawęcki
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacogenetics to Avoid Adverse Drug Reactions
| Pharmacogenetics to Avoid Adverse Drug Reactions |
| Autore | López-Fernández Luis A |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (220 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
5-fluorouracil
capecitabine fluoropyrimidine thymidylate synthase thymidylate synthase enhancer region upstream stimulatory factor 1 adverse drug reactions pharmacogenomics epistasis random forest statin cardiovascular disease colorectal cancer personalised medicine toxicity (es)citalopram drug-gene-interaction drug-drug-interaction drug-drug-gene-interaction the PharmLines initiative antipsychotic agents pharmacogenetics cytochrome P-450 enzyme system psychotic disorders precision medicine direct oral anticoagulants clinical implementation atorvastatin SLCO1B1 HLA cutaneous adverse drug reaction SCAR genetic polymorphism antiepileptics CYP450 enzymes platelet reactivity single-nucleotide variants acute coronary syndrome clopidogrel genotype allele polymorphism HLA B CYP2C9*3 cutaneous adverse drug reactions (CADRs) anti-epileptic drugs (AEDS) phenytoin (PHT) genetic risk factors South India India cardiology adverse events guidelines |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557610103321 |
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López-Fernández Luis A
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Precision Medicine : Applied Concepts of Pharmacogenomics in Patients with Various Diseases and Polypharmacy
| Precision Medicine : Applied Concepts of Pharmacogenomics in Patients with Various Diseases and Polypharmacy |
| Autore | Turgeon Jacques |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
fibromyalgia (FM)
myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) microRNA miRNome pharmacogenomics pharmacoepigenomics SM2miR Pharmaco-miR repoDB ME/CFS Common Data Elements (CDEs) dihydropyrimidine dehydrogenase DPYD 5-fluorouracil fluoropyrimidine therapeutic drug monitoring orthotopic liver transplant busulfan glutathione S-transferase genetic polymorphism limited sampling strategy pharmacokinetics clinical pharmacogenetics pharmacogenetic testing adverse drug reactions genotype phenotype pharmacogene barriers to pharmacogenetics implementation Sub-Saharan Africa chronic low back pain (cLBP) genetics personalized treatment polymorphism CYP450 tacrolimus CYP3A5 liver transplant pharmacogenomic minority data collection drug biomarker pharmacogenetics pharmacogenetic test personalized medicine gene expression infliximab adalimumab ulcerative colitis Crohn disease inflammatory bowel disease |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Precision Medicine |
| Record Nr. | UNINA-9910585940803321 |
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Turgeon Jacques
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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