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Advance in the Treatment of Pediatric Leukemia
| Advance in the Treatment of Pediatric Leukemia |
| Autore | Handgretinger Rupert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
acute lymphoblastic leukemia
pediatric advances diagnosis treatment immunotherapy bispecific T-cell engager (BiTE) BCP-ALL leukemia TRAIL antibody Fc-engineering xenograft CD19 juvenile myelomonocytic leukemia RAS signaling hematopoietic stem cell transplantation 5-azacitidine myelodysplastic/myeloproliferative disorders targeted therapy ADC antibody-drug conjugate pediatric leukemia ALL AML allogeneic stem cell transplantation acute myeloid leukemia minimal residual disease conditioning regimen alternative donors B-ALL DUX4 IKZF1 PAX5 Ph-like ZNF384 NUTM1 T-ALL NOTCH1 BCL11B transcriptome genome chronic myeloid leukemia CML tyrosine kinase inhibitor immunizations COVID-19 childhood acute lymphoblastic leukemia low-risk ALL risk-stratified treatment treatment related toxicity L-asparaginase acute pancreatitis polymorphism SNV ABCC4 CFTR other extramedullary relapse lymphoblastic leukemia children prognosis evolution of CAR T cells FDA-approved CAR products TcR versus CAR limitations and complications of CAR T cell therapy future directions of CAR T cell therapy |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878903321 |
Handgretinger Rupert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Experimental and Clinical Treatment of Subarachnoid Hemorrhage after Rupture of Saccular Intracranial Aneurysms
| Experimental and Clinical Treatment of Subarachnoid Hemorrhage after Rupture of Saccular Intracranial Aneurysms |
| Autore | Marbacher Serge |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (132 p.) |
| Soggetto topico |
Medicine
Surgery |
| Soggetto non controllato |
syncope
acute myeloid leukemia intracranial hemorrhage hyperleukocytosis blast crisis subarachnoid hemorrhage IL-1α inflammation animal model growth aneurysm rupture saccular intracranial aneurysm aneurysm cerebral aneurysm aneurysmal subarachnoid hemorrhage delayed cerebral vasospasm ischemic stroke Sartans therapeutic interventions ventriculomegaly diffusion tensor imaging corticospinal tract decellularization rabbits vessel wall aneurysm clipping posterior circulation aneurysm temporary balloon occlusion intraoperative digital subtraction angiography hybrid operating room estrogen female endothelial cell macrophage |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557703503321 |
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Marbacher Serge
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Integrative Multi-Omics in Biomedical Research
| Integrative Multi-Omics in Biomedical Research |
| Autore | Gerner Christopher |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (178 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
target identification
target validation label-free method for drugs anti-angiogenesis mechanism of action receptor tyrosine kinases curcumin natural products lipid lipidomics cardiac metaplasia Barrett's esophagus esophageal adenocarcinoma microbiota DNA sensing IFI16 cGAS innate immunity protein interactions virus-host interactions post-translational modifications mass spectrometry proteomics transcriptomics multi-omics multi-omics analysis study design bioinformatics machine learning analysis flow metabolomics planned myocardial infarction (PMI) myocardial infarction (MI) exercise heart cheminformatics batch variations eicosanoids fetal calf serum peroxisomes host-pathogen interactions secretome macrophages acute myeloid leukemia HL-60 cell line ATRA induced differentiation transcriptome proteome transcription factors key molecules regulatory pathway modelling SRM endometriosis inflammation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557769003321 |
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Gerner Christopher
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR in Human Diseases
| mTOR in Human Diseases |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN | 3-03921-061-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
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Dormond Olivier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments in Cancer Systems Biology
| Recent Developments in Cancer Systems Biology |
| Autore | Sinha Raghu |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (272 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Sestrin2
lung cancer knockdown cancer progression bioinformatics patient survival lung adenocarcinoma circulating miR-1246 glycosaminoglycan binding prognosis PI3K-Akt signaling pathways TargetScan UBE2C cancer systems biology experimental model systems next-generation sequencing single-cell sequencing patient-derived xenografts patient-derived organoids triple-negative breast cancer personalized medicine computational methods drug repurposing clinical trials cancer stem cells ETS Elk-1 stem cell microarray brain-tumor-initiating cell (BTIC) pancreatic cancer systems biology omics biomarker genomics transcriptomics proteomics metabolomics glycomics metagenomics Ets PEA3 Ets-1 glioma optical genome mapping solid tumors cancer genomics breast ovarian cancer TCGA non-small-cell lung cancer lung adenocarcinoma (LUAD) lung squamous cell carcinoma (LUSC) differential expression SNV CNV risk group signature survival renal cancers protein interactome diagnostic biomarker prognostic biomarker virtual screening docking acute myeloid leukemia Boolean model drug resistance network |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557768503321 |
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Sinha Raghu
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2
| Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2 |
| Autore | Luparello Claudio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
berberine
signaling pathways oncogenic cascades TRAIL microRNAs cancer therapy colon cancer cells ethanol Nrf2 HO-1 ER stress autophagy MMPs formononetin cancer preclinical models cell signaling angiogenesis nobiletin colorectal cancer chemoprevention bioactivities experimental therapeutics HDAC multiple myeloma oleacein breast cancer persistent organic pollutants breast cancer risk breast cancer prognostic systematic review carrageenan invasion metastasis RacGAP1 radiotherapy marine sponge natural product anticancer drug oral cancer inhibition phytochemicals small organic agents Piper eriopodon, alkenylphenols human cancer cells cell death apoptosis caspase-independent cell death XIAP antagonists XIAP-BIR3 domain Calocedrus formosana lung cancer yatein cell-cycle arrest xenograft isorhamnetin G2/M arrest ROS AMPK pancreatic cancer epigallocatechin-3-gallate (EGCG) gemcitabine glycolysis phosphofructokinase natural polyphenols anticancer activities molecular mechanisms Streptomyces mangrove anti-proliferative colon cancer epithelial mesenchymal transition inflammation malignant cancer natural anti-inflammatory compounds pro-resolving lipids anticancer drugs flavonoids natural compounds Xenopus laevis AOM/DSS model melanoma cells nicotine α9-nAChR PD-L1 STAT3 gigantol AKT JAK/STAT cancer stem cell tumor maintenance tumor density proteomics honokiol anticancer mechanism signalling pathway uterine sarcoma fucoidan isobolography colchicine alkaloid mesoporous silica nanoparticles targeted delivery system PD-1 immune checkpoint inhibitor and cancer immunotherapy glucose transport drugs innate immunity β-glucans nutrition immunotherapy estrogen estrogen receptor alpha polyphenols daidzein daidzein metabolites paclitaxel breast cancer cells obesity renin-angiotensin system eicosapentaenoic acid adipocyte inflammation olive leaf extract oleuropein Seahorse analysis cancer metabolism glycolytic markers Malva pseudolavatera Webb & Berthel acute myeloid leukemia reactive oxygen species brain cancer gliomas schwannomas malignant tumors of the peripheral nerve sheath (MPNST) neurofibromas bioavailability nanoparticle-based delivery systems natural bioactive compound gallic acid EGFR signaling p53 EGCG non-coding RNAs anti-cancer drug NSCLC EGFR TKI FASN inhibitors resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Role of Natural Bioactive Compounds in the Rise and Fall of Cancers |
| Record Nr. | UNINA-9910557476303321 |
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Luparello Claudio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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