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Molecular Psychiatry
| Molecular Psychiatry |
| Autore | Rein Theo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Mental health services |
| Soggetto non controllato |
cardiovascular disease
cell adhesion molecules immunology inflammation nervous system schizophrenia bipolar disorder major depressive disorder DNA methylation response variability antipsychotics drug design multi-target drugs polypharmacology multi-task learning machine learning biomarker discovery psychiatry serotonin 5-HT 4 receptor 5-HT4R depression mood disorder expression Alzheimer's disease cognition Parkinson's disease forced swimming Roman rat lines stress hippocampus BDNF trkB PSA-NCAM western blot immunohistochemistry general cognitive function intelligence GWAS genetic correlation childhood-onset schizophrenia (COS) induced pluripotent stem cell (iPSC) copy number variation (CNV) early neurodevelopment neuronal differentiation synapse dendritic arborization miRNAs stress physiology cytoskeleton actin dynamics DRR1 TU3A FAM107A acid sphingomyelinase alcohol dependence liver enzymes sphingolipid metabolism withdrawal Hsp90 GR stress response steroid hormones molecular chaperones psychiatric disease circadian rhythms FKBP51 FKBP52 CyP40 PP5 DISC1 neurodevelopment CRMP-2 proteomics antidepressant treatment HPA axis gene expression FKBP5 sleep sleep EEG biomarkers antidepressants cordance gender sex difference antidepressant rapid-acting Ketamine endocrinology (2R,6R)-Hydroxynorketamine electroconvulsive therapy basic-helix-loop-helix brain coactivator glucocorticoids mineralocorticoid receptor knockout transcription biology dopaminergic gene polymorphisms affective temperament obesity alpha-synuclein SNCA major depression Hamilton Scale of Depression chemokines neuroinflammation social defeat Immune response T cells susceptibility resilience Treg cells Th17 cells behavior PPARγ |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557793503321 |
Rein Theo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Symmetry Breaking in Cells and Tissues
| Symmetry Breaking in Cells and Tissues |
| Autore | Goryachev Andrew |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
actin waves
curved proteins dynamic instability podosomes diffusion cell polarity Cdc42 stress cellular memory phase separation prions apoptotic extrusion oncogenic extrusion contractility actomyosin bottom-up synthetic biology motor proteins pattern formation self-organization cell motility signal transduction actin dynamics intracellular waves polarization direction sensing symmetry-breaking biphasic responses reaction-diffusion membrane and cortical tension cell fusion cortexillin cytokinesis Dictyostelium myosin symmetry breaking cytoplasmic flow phase-space analysis nonlinear waves actin polymerization bifurcation theory mass conservation spatial localization activator–inhibitor models developmental transitions cell polarization mathematical model fission yeast reaction–diffusion model small GTPases Cdc42 oscillations pseudopod Ras activation cytoskeleton chemotaxis neutrophils natural variation modelling activator-substrate mechanism mass-conserved models intracellular polarization partial differential equations sensitivity analysis GTPase activating protein (GAP) fission yeast Schizosaccharomyces pombe CRY2-CIBN optogenetics clustering positive feedback network evolution Saccharomyces cerevisiae polarity modularity neutrality |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557440703321 |
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Goryachev Andrew
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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