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10th Anniversary of Cells—Advances in Cell Cycle
| 10th Anniversary of Cells—Advances in Cell Cycle |
| Autore | Wang Zhixiang |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (194 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
5-bromo-2'-deoxyuridine
aberrant mitosis actin APC/C complex apoptosis BPA-C8-Cy3 Ca2+ signaling cancer Cdc15 CDK cell cycle cell cycle arrest cerebellar neuroepithelium confocal Raman microscopy CTD code CTD phosphatase Dbf2 Desmodesmus quadricauda DTT electron microscopy external granular layer fertilization G1 phase G2 phase glioblastoma growth factors guanine hormesis HSF1 HSF2 LDIR Leishmania spp leishmaniases lipids M phase M2 muscarinic receptor MEN microalgae mitotic exit mitotic spindle Mob1 n/a neurogenetic gradients neurogenetic timetables Nud1 p21Waf1(CDKN1A) perinatal life PI3K/Akt plasticity polyphosphate prenatal life Ras/Erk receptor tyrosine kinases RNA polymerase II S phase sea urchin eggs spindle position checkpoint starch TCEP telomerase telomeres transcription vitelline layer |
| ISBN | 3-0365-5215-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619471503321 |
Wang Zhixiang
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (606 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
1,2,3-triazole
2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide 3,6-dibromocarbazole 4-(pyridin-4-yloxy)benzamide 5-bromoindole 5-fluorouracil ABCB1 (P-glycoprotein) actin ADME allene amides/esters androgen receptor anti-cancer activity anti-neuroinflammation anti-ovarian cancer anti-tumor anticancer anticancer activity anticancer agent anticancer agents anticancer compounds antimitotic agents antioxidant activity antiproliferative activity antiproliferative agent antitumor antitumor activity apalutamide apoptosis aromatase benzimidazole benzofuran-pyrazole benzofurans beta-lapachone bivalency breast cancer c-Met carbazole cell cycle chemical synthesis chemoresistance chrysin analogues colchiceine colchicine amide colchicine analogs colchicine sulfonamide colon cancer computational docking coumarin crystal structure cyanopyridone cytotoxic activity cytotoxic properties cytotoxicity darolutamide DFT study dihydroartemisinin dihydropyranoindole docking docking studies drug discovery drug resistance E-stereoselective enzalutamide enzyme inhibition estrone derivatives flavonoid flavonoids gemcitabine HDAC inhibitors HeLa HepG2 hydrates hydrazine IGF-1R IL-12 immune modulation indoleamine 2,3-dioxygenase inflammation inhibitor K562 kinase inhibitor MCF-7 MDM2-p53 interaction migration mimetics molecular simulation MOLT-4 multidrug resistance (MDR) reversal N-substituted pyrazoline nanoparticles natural product neuroblastoma NIH3T3 o-nitro-benzyl organosilicon compounds ortho-quinones ovarian cancer overcoming drug resistance P-glycoprotein P-MAPA PARP inhibitor PARP-1 inhibition phenylpyrazolopyrimidine photoactivatable protecting groups PI3Ks PI3Kα inhibitor PI3Kδ inhibitors polyvalency prodrug prostate cancer PROTACs protein degradation protein kinase protein-protein interactions Pyrazole pyrazolopyridine pyridotriazine quinazolin-4(3H)-one quinazolin-4(3H)-thione regioselective salinomycin Schiff base SILA-409 (Alis-409) SILA-421 (Alis-421) Src substituted pyridine synergy synthesis Talazoparib tanshione IIA taxoids thiazolidinone Thienopyrimidine thienopyrimidinone thiocolchicine thiopene thioxotriazopyridine TLR signaling topoisomerase II inhibitor triazolothiadiazine triple-negative breast cancer tryptophan metabolism tubulin inhibitors tumor specificity urea virtual screening xanthones yeast-based assays zampanolide βIII-tubulin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
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Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Nanomedicine
| Cancer Nanomedicine |
| Autore | Hoskins Clare |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (510 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
actin
active targeting acute toxicity adsorption albumin albumin nanoparticle albumin nanoparticles anacardic acid angiogenesis anti-cancer anti-metastatic enzyme cancer therapy anti-topoisomerase activity anti-tumor immunity antibody drug conjugate (ADC) anticancer and antibacterial activity antitumor strategy apoptosis ascorbic acid BALB-neuT mice biodistribution biomimetic biomimetic core-shell nanoparticles biomimicry bleeding blood brain barrier brain tumours breast cancer cabazitaxel cancer cancer diagnosis cancer nanomedicine cancer therapy cathepsin D cathepsin L cats cell signaling cellular interaction cellular microenvironment chemico-physical functionalization chemotherapeutics chirality separation clinical status clinical translation collagen colloidal stability colorectal carcinoma combinatorial therapy copper CPMV CSCs cyclodextrins cytotoxicity diagnostics differentiated neuroblastoma dioleoylphosphatidylethanolamine DNA origami docetaxel dogs DOX doxorubicin drug combination drug delivery drug delivery system drug-gene delivery drug-in-cyclodextrin-in-liposome dual-targeting epithelial-to-mesenchymal transition EPR effect erlotinib everolimus exosomes extracellular vesicles FA-DABA-SMA flow folate folate receptor folic receptor alpha glioblastoma glioma gold nanoparticles gold nanorods graphene oxide hepatocellular carcinoma hyaluronic acid hyaluronidase hybrid nanoparticles hyperthermia hyperthermia therapy hypoxia imaging immune modulation immunosuppression immunotherapy Immunotherapy in situ vaccine in vitro in vitro anti-cancer activity integrin intra-arterial chemotherapy intracellular disruption intracranial glioma iron affinity lanthanide metal ligand lipid nanoparticles liposome liposomes loading lung cancer lymphadenectomy magnetic actuation magnetic drug targeting magnetic hyperthermia magnetic nanoparticles magnetic nanowires magnetic silica-coated iron oxide nanochains magnetometer mammary carcinoma mangiferin MDA-MB-231 melanoma membrane-wrapped mesenchymal stem cells (MSCs) Mesoporous silica nanoparticle mesoporous silica nanoparticles metabolism microbubble microfluidic mitoxantrone mixed micelle molecular imaging monoclonal antibodies multicellular tumor spheroids nano-bio interactions nano-engineered MSCs nanobiotechnology nanocarrier nanomedicine nanomedicines nanomicelles nanoparticle nanoparticles nanostructured lipid carrier nanosystems nanotechnology: bioengineering nanotherapeutics NASH near IR hyperspectral imaging NK cell-derived exosomes oncogenes oncogenic proteins organoids organotin orthotopic lung tumor model osteopontin ovarian cancer ovarian carcinomatosis oxidation-sensitive release paclitaxel pancreatic cancer parvifloron D passive targeting PD-L1 PEGylation peptidomimetics pH responsive photodynamic therapy photodynamic therapy article photothermal therapy photothermal treatment plasmonic photothermal therapy plasmonics platelet membrane PLGA poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer polydopamine nanoparticles polymeric nanoconstruct polymeric nanoparticles prostate cancer radiotherapy real-time quantitative polymerase chain reaction (qPCR) remote loading RGD peptide riboflavin secondary structure self-assembly sentinel lymph node dissection shear stress single-walled carbon nanotubes siRNA size SN38 spheroids SPION stimuli-responsive superparamagnetic iron oxide nanoparticles surgery target treatment targeted delivery targeted delivery system targeted drug delivery targeted therapy TAT peptide temoporfin theranostic nanomaterials theranostics therapeutics titanate nanotubes translational medicine triple negative breast cancer tumor microenvironment tumor spheroid disruption tumor targeting tumor vectorization tumour microenvironment tumour targeting ultrasound vectorization VEGF verteporfin viral nanoparticles vitamin B2 VX2 tumor Vδ2 T cells yet reasonably common within the subject discipline zoledronic acid β-cyclodextrin nanosponges |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557114703321 |
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Hoskins Clare
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Microbial Virulence Factors
| Microbial Virulence Factors |
| Autore | Leitão Jorge H |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (400 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
5637 bladder cells
actin actin proteolysis Actinomycetales Aeromonas hydrophila anti-virulence antibiotic resistance antimicrobial peptide antimicrobial peptides apple apple proliferation autotransporter bacteria bacterial invasion bacterial pathogens bacterial surface protein biofilm biofilm formation blood-brain barrier blood-cerebrospinal fluid barrier Bordetella pertussis Burkholderia cepacia complex Candida Candida albicans chronic infection Citrobacter coagulase-negative staphylococci complement compound appressorium covalent labeling cystic fibrosis cytotoxicity Dickeya solani differential expression proteins EDTA effector protein Enterobacter Enterobacterales fluconazole fungal pathogens fungicidal activity gelatin gene expression global regulator grimelysin Hfq host-pathogen interaction hyphae immune evasion immune response infection inflammation inter-kingdom protection interspecies interactions intracellular survival Klebsiella lon expression LysR-family manipulation meningitis metalloproteinases microbial virulence factors morphology motility mucin omics analysis outer membrane vesicles (OMVs) oxidative stress pathogenicity pathogenomics pectinolytic enzymes persistence phytoplasma plant pathogen primary ciliary dyskinesia protealysin protease ECP 32 protease Lon proteomics analysis Pseudomonas aeruginosa pyolysin replicative niche resistance to stress Salmonella enterica serovar Typhimurium Sclerotinia sclerotiorum serine proteases serum resistance small noncoding regulatory RNAs solute-binding proteins SPATEs sputum SpyCatcher SsNsd1 T3SS topology mapping truA Trueperella pyogenes two-dimensional electrophoresis type III secretion system usg UTIs virulence virulence factor virulence factors whole genome sequencing ΔlahS |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557746603321 |
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Leitão Jorge H
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Structure, Activity, and Function of Protein Methyltransferases
| Structure, Activity, and Function of Protein Methyltransferases |
| Autore | Jeltsch Albert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (292 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research & information: general |
| Soggetto non controllato |
actin
actin cytoskeleton AML arginine methylation cancer cardiovascular disease cell proliferation cell signaling chromatin regulation congenital heart diseases cytoskeleton dendritic spine diabetes disease DNA damage repair dystonia eEF1A EHMT1 EHMT2 enteroviruses enzyme regulation enzyme specificity epigenetics G9a GLP GTPase H3K36 H3K36me2 H3K4me3 H3K9 methylation H3R2me2a H4R3 methylation heterochromatin histone Hsmar1 Huntington's disease immunity inflammation inflammatory bowel disease lysine methylation lysine-specific methyltransferase (PKMT) methyltransferase Metnase METTL13 MLL2 N-terminal methylation n/a neurodegenerative diseases neuron NHEJ non-homologous end joining repair NSD1 NSD3 NUP98-NSD1 oncogenesis PKMT pluripotency polymerization post translational modification post-translational modification post-translational protein modification posttranslational modifications Prader-Willi syndrome PRMT1 PRMT2 PRMT5 PRMT6 PRMT7 protein arginine methylation protein histidine methylation protein lysine methylation protein post-translational modification Rett syndrome schizophrenia SET7/9 SETD3 SETD7 SETDB1 SETMAR SH3 SOTOS stress response structure structure and function synapse transcriptional regulation translation transposable elements transposase WHSC1L1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566479603321 |
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Jeltsch Albert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Amazing World of IDPs in Human Diseases
| The Amazing World of IDPs in Human Diseases |
| Autore | Monti Simona Maria |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (196 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
actin
alpha-synuclein cancer circular dichroism cytoskeleton remodeling de novo EPR spectroscopy evolutionary origin flexibility fluorescence gene duplications human disease importin interface core and rim intrinsically disordered protein intrinsically disordered protein (IDP) intrinsically disordered proteins intrinsically disordered regions isothermal titration calorimetry isothermal titration calorimetry (ITC) linear motifs Methyl-CpG-binding protein 2 (MeCP2) molecular docking molecular recognition features n/a NADH-26S proteasome neurodegenerative diseases NMR nuclear magnetic resonance (NMR) nuclear protein 1 (NPR1) peptide pre-structured motifs (PreSMos) proline-rich motif protein degradation protein misfolding protein stability protein structural dynamics protein-DNA interaction protein-ligand interaction protein-protein interactions proteostasis Rett syndrome secondary structure propensity SH3 domain single nucleotide variants site-directed spin labeling ubiquitin independent degradation ubiquitin-proteasome system WASp interacting protein |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557334303321 |
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Monti Simona Maria
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder
| The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder |
| Autore | Leone Marilisa |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (230 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
ABC transporter
ACE2 actin advanced sampling 5 antifungal activity apparent gas phase activation energies apparent gas phase dissociation constants ATP analogues ATP hydrolysis backbone atom coordinate variances and uncertainties binding 2 bioinformatics biopesticides cancer charged amino acids cofactor binding and release cytoskeleton deafness denatured state ensemble disordered structure DnaB helicase ELDOR-detected NMR Friedman's test gas phase immune complex dissociation hearing loss High Hydrostatic Pressure IDP 1 immunoglobulin domain insecticidal activity interdomain cleft dynamics intrinsically disordered proteins ion-pairing interaction ITEM-TWO mass spectrometric epitope mapping MDM2 7 mechanism of action MELD×MD 4 mental illness molecular dynamics 3 molecular dynamics simulations n/a NAD(P)H-dependent oxidoreductase nanobody native mass spectrometry NMR p53 6 peptide peptides protein aggregation protein coil library protein folding protein structure SARS-CoV-2 schizophrenia side-chain length solid-state NMR superimposition transgenic crops transmission TRIOBP viral spike receptor-binding domain zinc-containing alcohol dehydrogenase β-hairpin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Conformational Universe of Proteins and Peptides |
| Record Nr. | UNINA-9910557371103321 |
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Leone Marilisa
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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