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Emerging Role of Lipids in Metabolism and Disease
| Emerging Role of Lipids in Metabolism and Disease |
| Autore | Pallottini Valentina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (308 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
neutral sphingomyelinase
radiation sphingomyelin metabolism pathology cell signaling brain adipose tissue breast cancer epinephrine breast reconstruction epicardial fat thickness visceral fat thickness high-sensitivity c-reactive protein leptin gender female hippocampus frontal cortex adiponectin haptoglobin lipocalin BDNF synaptic proteins phosphatidylinositol 4,5-bisphosphate phospholipase C cholesterol high-cholesterol diet BET proteins cell proliferation epigenetics HMGCR JQ1 LDLr lipid metabolism SREBP TMEM97 atherosclerosis diabetes mellitus cardiovascular disease chronic inflammation hyperglycemia mutations lipid fatty acid glyceride steroid phospholipid oral drug absorption prodrug phospholipase A2 (PLA2) acid sphingomyelinase SOD liver eicosanoids ischemic stroke ischemia lipoproteins polyunsaturated fatty acids angiogenesis high-density lipoprotein endothelial cell metabolism metabolic reprogramming pulmonary fibrosis lipid mediators sphingolipids sphingosine-1-phosphate sphingosine kinase 1 prostaglandins lysophosphatidic acid autotaxin G-protein coupled receptors lysocardiolipin acyltransferase phospholipase D oxidized phospholipids DNA damage response double strand breaks ATM ionizing radiation metabolic stress oxidative stress p53 nuclear sphingolipids lipophagy lipolysis lipid droplets lipid storage diseases lipid metabolism diseases mTORC1 TFEB Cholesterol Fatty acids Lipid mediators Lipids Lipophagy Sphingolipids |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557800303321 |
Pallottini Valentina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Psychiatry
| Molecular Psychiatry |
| Autore | Rein Theo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Mental health services |
| Soggetto non controllato |
cardiovascular disease
cell adhesion molecules immunology inflammation nervous system schizophrenia bipolar disorder major depressive disorder DNA methylation response variability antipsychotics drug design multi-target drugs polypharmacology multi-task learning machine learning biomarker discovery psychiatry serotonin 5-HT 4 receptor 5-HT4R depression mood disorder expression Alzheimer's disease cognition Parkinson's disease forced swimming Roman rat lines stress hippocampus BDNF trkB PSA-NCAM western blot immunohistochemistry general cognitive function intelligence GWAS genetic correlation childhood-onset schizophrenia (COS) induced pluripotent stem cell (iPSC) copy number variation (CNV) early neurodevelopment neuronal differentiation synapse dendritic arborization miRNAs stress physiology cytoskeleton actin dynamics DRR1 TU3A FAM107A acid sphingomyelinase alcohol dependence liver enzymes sphingolipid metabolism withdrawal Hsp90 GR stress response steroid hormones molecular chaperones psychiatric disease circadian rhythms FKBP51 FKBP52 CyP40 PP5 DISC1 neurodevelopment CRMP-2 proteomics antidepressant treatment HPA axis gene expression FKBP5 sleep sleep EEG biomarkers antidepressants cordance gender sex difference antidepressant rapid-acting Ketamine endocrinology (2R,6R)-Hydroxynorketamine electroconvulsive therapy basic-helix-loop-helix brain coactivator glucocorticoids mineralocorticoid receptor knockout transcription biology dopaminergic gene polymorphisms affective temperament obesity alpha-synuclein SNCA major depression Hamilton Scale of Depression chemokines neuroinflammation social defeat Immune response T cells susceptibility resilience Treg cells Th17 cells behavior PPARγ |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557793503321 |
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Rein Theo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sphingolipids : From Pathology to Therapeutic Perspectives - A Themed Honorary Issue to Prof. Lina Obeid
| Sphingolipids : From Pathology to Therapeutic Perspectives - A Themed Honorary Issue to Prof. Lina Obeid |
| Autore | van Echten-Deckert Gerhild |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (292 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
S1P receptor
inflammation S1P transporter spinster homolog 2 barrier dysfunction anxiety depression sphingolipids sphingomyelinase ceramidase Smpd1 acid sphingomyelinase forebrain depressive-like behavior anxiety-like behavior ceramide ceramides ceramidases neurodegenerative diseases infectious diseases sphingosine 1-phoshate sphingosine 1-phosphate receptor S1P1-5 sphingosine 1-phosphate metabolism sphingosine 1-phosphate antagonistst/inhibitors sphingosine 1-phosphate signaling stroke multiple sclerosis neurodegeneration fingolimod Sphingosine-1-phosphate obesity type 2 diabetes insulin resistance pancreatic β cell fate hypothalamus sphingosine-1-phosphate ischemia/reperfusion cardioprotection vasoconstriction coronary flow myocardial function myocardial infarct albumin type 1 diabetes beta-cells islets insulin cytokines S1P animal models cystic fibrosis autophagy myriocin Aspergillus fumigatus CLN3 disease Cln3Δex7/8 mice flupirtine allyl carbamate derivative apoptosis cancer gangliosides immunotherapy metastasis phenotype switching sphingosine 1-phosphate Sphingosine 1-phosphate (S1P) S1P-lyase (SGPL1) tau calcium histone acetylation hippocampus cortex astrocytes neurons sphingosine kinase G-protein-coupled receptors Gαq/11 sphingosine kinase 1 SK1 microRNA transcription factor hypoxia long non-coding RNA |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Sphingolipids |
| Record Nr. | UNINA-9910557545203321 |
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van Echten-Deckert Gerhild
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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