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Advanced Electrochemical and Opto-Electrochemical Biosensors for Quantitative Analysis of Disease Markers and Viruses
| Advanced Electrochemical and Opto-Electrochemical Biosensors for Quantitative Analysis of Disease Markers and Viruses |
| Autore | Karimian Najmeh |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (166 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
gold nanoparticles
doxycycline tetracycline SPR biosensor signal amplification clinical diagnosis microRNA electrochemical biosensor catalysts RedOx indicator cancer biomarker electrochemical immune platform human ST2 plasma pancreatic cancer collagen type I 4,4'-thiobisbenzenethiol nanogold electrochemical impedance spectroscopy surface plasmon resonance half antibody medical diagnostic devices peptide antifouling protease biomarker bioreceptor SARS-CoV-2 detection nasopharyngeal swab saliva serum droplets amperometric biosensor neural esterase acetylcholinesterase inhibition organophosphate design optimization mathematical model flux control dimensionless |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580216603321 |
Karimian Najmeh
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances on Applications of Bioactive Natural Compounds
| Advances on Applications of Bioactive Natural Compounds |
| Autore | Seca Ana M. L |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
heterologous expression
Streptomyces secondary metabolite Garcinia xanthochymus growth inhibitory compounds allelopathy vanillic acid methyl phloretate allelopathic activity growth inhibitor phenolic compounds bioherbicide sustainable agriculture pulsed electric fields green extraction microalgae antioxidants pigments thymoquinone UHRF1 ubiquitination HAUSP tumor suppressor genes aaptoline B pyrroloquinoline Ag(I)-catalyzed cycloisomerization dopaminergic neuroprotection Parkinson's disease bioactive compounds cardiovascular nanodelivery bioavailability Ailanthus altissima biological properties analytical techniques potential applications propolis contamination propolis cytotoxicity antimicrobial activity antiprotozoal activity artepelin C formononetin pinocembrin quercetin kaempferol propolis extract Asparagopsis armata Rhodophyta GC-MS UHPLC-MS dibrominated compounds 1,4-dibromobuten-1-ol palmitic acid brominated phenolics red seaweed invasive seaweed invasive species flowers antioxidant microbial activity bioactivity enzyme inhibitory potential acetylcholinesterase lipase α-glucosidase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580214503321 |
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Seca Ana M. L
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antioxidants in Foods
| Antioxidants in Foods |
| Autore | Seiquer Isabel |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (418 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
green tea extract
food processing tannase ultrasound antioxidant activity liver injury acclimatisation antioxidant defences chlorophyll fluorescence in vitro culture peroxidase stevia plants 7S basic globulins anti-inflammatory protein antioxidant protein cytokines glutathione iNOS nitric oxide oxidative stress sweet lupins group home-cooking extra virgin olive oil UPLC-ESI-QqQ-MS/MS healthy cooking Mediterranean diet phenolic compounds bioactive compounds functional pasta gluten-free pasta bioaccessibility bioavailability whole grain composite flour legumes food by-products avocados (Persea americana Mill.) low temperatures plastochromanol-8 tocotrienols tocopherols tocochromanols kombucha tea fermentation antioxidant flavonoids polyphenols ascorbic acid chlorophyll and carotenoid content biodiversity Capsicum annuum L. β-carotene statistical analysis rye bread microencapsulation phenolics in vitro relative bioaccessibility lipoxygenase cyclooxygenase acetylcholinesterase biological activity lycopene antioxidants cancer diabetes cardiovascular diseases skin disorders free radicals spectrophotometer limitations chemical reactions colorimetry anthraquinone free radical scavenging inflammatory cytokines apoptosis Rumex crispus skins seeds Vitis vinifera cyclic voltammetry anthocyanin metabolites cardioprotection hepatoprotection nephroprotection neuroprotection antioxidant peptides element of pork carcasses spectrometric analysis ascorbate ascorbate-glutathione cycle capsaicin catalase dihydrocapsaicin NADP-dehydrogenases superoxide dismutase red cabbage in vitro gastrointestinal digestion acid-resistant capsule UHPLC-Q-Orbitrap HRMS apples reducing and chelating capacity HPLC-DAD-MS/MS Dillenia indica heme oxygenase 1 (HO-1) nuclear factor erythroid 2-related factor 2 (Nrf2) RAW 264.7 cells apo-carotenals bone osteoclasts NFκB synergy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557728503321 |
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Seiquer Isabel
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Marine Heterocyclic Compounds
| Bioactive Marine Heterocyclic Compounds |
| Autore | Usami Yoshihide |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (132 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
altercrasins
Alternaria sp Anthocidaris crassispina decalin derivatives cytotoxicity mangrove plant endophytic fungus Cladosporium cladosporioides polyketides antimicrobial activity acetylcholinesterase enzymatic inhibitory activity genome sequencing gene disruption lobophorin metabolic engineering genome mining solid-state fermentation solid-state extraction Chrysosporium lobatum marine fungi phenalenone derivatives antibiotics natural product P. gingivalis methicillin-resistant S. aureus azole-based peptide marine sponge peptide synthesis cyanobacteria thiazole bioactivity agesasines bromopyrrole alkaloid Agelas |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557762703321 |
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Usami Yoshihide
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological Activities of Alkaloids: From Toxicology to Pharmacology
| Biological Activities of Alkaloids: From Toxicology to Pharmacology |
| Autore | Adamski Zbigniew |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto non controllato |
leukemia
biodistribution glycoalkaloids insect heart Solanum melongena L. antibacterial alkaloid ?-carboline Ovarian cancer Chelidonium majus secondary metabolites lindoldhamine livestock insect chanoclavine bisbenzylisoquinoline alkaloid cytotoxic activity Staphylococcus aureus antioxidant acid-sensing ion channel subtype 1a malonylated form HPLC-DAD ergot alkaloids nociception macrophage Arecoline Macleaya cordata antifungal neuropathic pain Corydalis lutea antiviral Curine lung cancer cells lipopolysaccharide Epichloë Meconopsis cambrica Berberis thunbergii SRC Dicentra spectabilis apoptosis endophyte natural sources dehydrocrenatidine neutrophil EGFR anticancer solamargine berberine isoquinoline alkaloids natural products Radix Aconiti Lateralis preparations short-term and long-term usage inflammation acute toxicity Mahonia aquifolia Palmatine sanguinarine Rutidea parviflora voltage-gated sodium channels cytotoxicity toxicology malonyl-solamargine alkaloids acetylcholinesterase beetles Fumaria officinalis antimicrobial activity solasonine FAK plant secondary metabolites di-ester diterpenoid alkaloids mAchR3 subchronic feeding study mono-ester diterpenoid alkaloids Tenebrio molitor Apoptosis reproduction |
| ISBN | 3-03928-928-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Biological Activities of Alkaloids |
| Record Nr. | UNINA-9910404082303321 |
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Adamski Zbigniew
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cholinesterase Research
| Cholinesterase Research |
| Autore | Korabecny Jan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (223 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Amaryllidaceae
Narcissus pseudonarcissus cv. Carlton alkaloids carltonine A-C Alzheimer's disease butyrylcholinesterase docking studies organophosphorus nerve agents oxime cholinesterase reactivation ventilation pharmacodynamics blood-brain barrier crossing acetylcholinesterase inhibitors bone healing osseointegration donepezil hemostasis acetylcholinesterase inhibitor dementia zebrafish behavior Alzheimer disease antioxidants butyrylcholinesterase inhibitors molecular modelling nutraceuticals phytochemicals acetylcholinesterase slow-binding inhibition transition state analog organophosphorus osmotic stress neutron scattering molecular dynamics MD simulations fluorene in vitro in silico multi-target directed ligands N-methyl-d-aspartate receptor molecular modeling reactivators reactivation process organophosphates docking hydrolysis molecular recognition catalysis inhibition |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557764703321 |
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Korabecny Jan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
| Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics |
| Autore | Tutone Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (387 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
3D-QSAR
pharmacophore modeling ligand-based model HDACs isoform-selective histone deacetylase inhibitors aminophenylbenzamide hERG toxicity drug discovery fingerprints machine learning deep learning gene expression signature drug repositioning approaches RNA expression regulation high-throughput virtual screening dual-target lead discovery neurodegenerative disorders Alzheimer's disease dual mode of action multi-modal nicotinic acetylcholine receptor acetylcholinesterase molecular docking methotrexate drug resistance human dihydrofolate reductase virtual screening molecular dynamics simulation epitope binning epitope mapping epitope prediction antibody:antigen interactions protein docking glycoprotein D (gD) herpes simplex virus fusion proteins Src inhibitors pharmacophore model molecular dynamics simulations in silico COX-2 inhibitors molecular modeling sodium-glucose co-transporters 2 FimH uropathogenic bacteria urinary tract infections diabetes drug-resistance mutations HIV-2 protease structural characterization induced structural deformations SARS-CoV-2 COVID-19 multiprotein inhibiting natural compounds MD simulation 3CL-Pro antivirals docking simulations drug repurposing consensus models binding space isomeric space MRP4 SNPs variants protein threading modeling molecular dynamics binding site hTSPO PK11195 cholesterol homology modeling molecular dynamics (MD) simulation carbon nanotubes Stone-Wales defects haeckelite defects doxorubicin encapsulation drug delivery system binding free energies noncovalent interactions main protease mutants inhibitors PF-00835231 Mycobacterium tuberculosis tuberculosis proteasome natural compounds multiscale multitargeting polypharmacology computational biology drug repositioning structural bioinformatics proteomic signature skin aging oxidative stress aging progression mechanism genome-wide genetic and epigenetic network (GWGEN) systems medicine design multiple-molecule drug immunoproteasome non-covalent inhibitors MD binding metadynamics induced-fit docking |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Computational Approaches |
| Record Nr. | UNINA-9910557519403321 |
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Tutone Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Enzyme Inhibitor from Marine Organisms
| Enzyme Inhibitor from Marine Organisms |
| Autore | Tischler Dirk |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (130 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
sponge Monanchora pulchra
pentacyclic guanidine alkaloids GH36 α-galactosidase GH109 α-N-acetylgalactosaminidase slow-binding irreversible inhibitor monanchomycalin B monanhocidin A normonanhocidin A Alzheimer′s disease BACE1 acetylcholinesterase in silico docking phlorotannins Ulva intestinalis ACE inhibitory peptide optimization purification structural identification molecular docking secondary metabolites Mycosphaerella sp asperchalasine α-glucosidase kinase inhibitors drug development marine natural products inhibitor macroalgae marine fish protease Ulva ohnoi functional annotation structure–function relation natural products bioactives enzyme inhibition inactivation marine bacteria marine fungi marine sponges |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557107603321 |
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Tischler Dirk
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Carotenoids
| Marine Carotenoids |
| Autore | Sugawara Tatsuya |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (744 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
fucoxanthin
scopolamine acetylcholinesterase Alzheimer’s disease cognitive impairments mytiloxanthin anti-oxidative activity singlet oxygen hydroxyl radical lipid peroxidation astaxanthin production carotenoids genome-reduced Corynebacterium glutamicum systematic approach metabolic engineering marine microalgae seaweeds nonconventional extraction electrotechnologies pulsed electric field-assisted extraction supercritical fluid extraction green processing microwave-assisted extraction marine drugs Bangia fuscopurpurea red algae lycopene cyclase carotenoid metabolism astaxanthin Escherichia coli β-carotene ketolase β-carotene hydroxylase Haematococcus pluvialis PII signaling protein nitrogen starvation gene cloning mRNA expression microalgae anti-angiogenic cardioprotective activity anti-cancer anti-diabetic anti-inflammatory anti-obesity anti-oxidant beauty Phaeodactylum tricornutum spectrophotometry high through-put screening antioxidants bioactive compounds blue biotechnology marine microorganisms ozonolysis apo-fucoxanthinone Caco-2 antiproliferative effect Pyropia yezoensis α-cryptoxanthin zeinoxanthin lutein-5,6-epoxide antheraxanthin carotenoid synthesis pathway red seaweed human papillomavirus 16 (HPV16) astaxanthin (Asta) acrosome reaction cholera toxin subunit B (CTB) L1 protein cigarette smoke exposure p38 MAPK antioxidant inflammatory synaptic-associated plasticity comparative transcriptome analyses alcoholic liver disease bioinformatic analysis phytoene fluridone cosmeceuticals anti-obesity effect Phaeodactylum extract Coelastrum canthaxanthin lutein nanoemulsion sublingual delivery ascorbyl palmitate Franz cell alcoholic liver injury oxidative stress Nrf2 TLR4 chronic obstructive pulmonary disease nuclear factor erythroid 2-related factor 2 heme oxygenase-1 siphonaxanthin dehydro-metabolite white adipose tissue metabolic pathway in vivo stereochemistry Tigriopus copepod meso-zeaxanthin zeaxanthin reactive oxygen species immune system antioxidant antibiotics thermal stress disease halocynthiaxanthin intestinal absorption functional food apoptosis inflammation lipid metabolism high-fat diet |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557148503321 |
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Sugawara Tatsuya
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Protein-Ligand Interactions: Target Identification and Drug Discovery
| Protein-Ligand Interactions: Target Identification and Drug Discovery |
| Autore | Altieri Fabio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
serum half-life extension
fatty acid conjugation FcRn-mediated recycling serum albumin translocator protein (TSPO) CoCl2 mitochondrial membrane potential reactive oxygen species (ROS) cell viability cell death lung cancer cell line acetylcholinesterase amyloid beta aggregation neuroprotection molecular docking multi-target drug structure–activity relationship brassicasterol phytosterols HSV Mycobacterium tuberculosis HSV-1 DNA polymerase HSV-1 TK human CDK2 ACE UDP-galactopyranose mutase heat shock protein 70 Hsp70 piperine fluorescence spectroscopy molecular dynamics molecular biophysics GADD45β MKK7 multiple myeloma protein-ligand interaction STD-NMR sigma receptors sigma ligands cancer SIGMAR1 PGRMC1 TMEM97 NCI60 COMPARE analysis membrane lipid-protein interaction lipid signalling kinase regulation phosphatidylinositols molecular docking simulation target identification small-molecule derivatives of salicylanilide drug discovery drug development thyroid diseases endocrine disruptor compound human umbilical artery vascular homeostasis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Protein—Ligand Interactions
Protein-Ligand Interactions Protein–Ligand Interactions |
| Record Nr. | UNINA-9910557497703321 |
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Altieri Fabio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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