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Disease and the Hippo Pathway: Cellular and Molecular Mechanisms
| Disease and the Hippo Pathway: Cellular and Molecular Mechanisms |
| Autore | Hansen Carsten Gram |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (226 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
adaptive immunity
angiogenesis anti-cancer therapy autoimmunity cancer cancer immunity castration resistance chromatin ECM EMT epigenetic feedback loops fibroblasts fibrosis G protein-coupled receptor GPCR Hippo hippo pathway Hippo pathway Hippo signalling innate immunity LATS LATS (large tumor suppressor kinase) LATS1/2 Lats2 Mps one binder MST MST (mammalian STE20-like protein kinase) MST1/2 myofibroblast n/a NDR peripheral nerve sheath tumor phosphorylation prostate cancer protein kinase protein-protein interactions schwannoma signal cross-talk signal transduction skin cancer skin development stem cell stem cells STK38 STRIPAK structure biology Taz TAZ TAZ (transcriptional co-activator with PDZ-binding motif) TEAD transcription tumorigenesis vascular mimicry wound healing Yap YAP YAP (yes-associated protein) YAP/TAZ zebrafish |
| ISBN | 3-03921-777-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Disease and the Hippo Pathway |
| Record Nr. | UNINA-9910367742003321 |
Hansen Carsten Gram
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges
| Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges |
| Autore | Gabazza Esteban C |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (348 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acute lung injury
anaplastic lymphoma kinase angiogenesis antitumor efficacy apoptosis bleomycin breast cancer butylidenephthalide cancer cancer-associated fibroblasts cancer-associated fibroblasts (CAFs) carcinogenesis cirrhosis clinical symptoms common pathways crizotinib cystic formation cytokine cytokines DHA diagnosis EMT Erk1/2 extracellular matrix fibrosis genetic instability GPR120 GPR40 growth factor HBV HCV hepatic stellate cells hepatic stellate cells (HSCs) hepatocellular carcinoma hepatocellular carcinoma (HCC) hepatocytes heterogeneity Hippo pathway idiopathic pulmonary fibrosis idiopathic pulmonary fibrosis (IPF) immunohistochemistry inflammation interstitial fluid pressure leiomyoma leiomyosarcoma lipopolysaccharide lncRNA lung cancer lung cancer (LC) marker mechanotransduction metabolic reprogramming metastasis miRNA myometrium n/a nanoparticles non-alcoholic steatohepatitis non-small cell lung cancer (NSCLC) omega-3 fatty acid pathogenesis pathology pathophysiology protein S pulmonary fibrosis reactive oxygen species regeneration renal injury signal pathway SMAD smooth muscle tumor of uncertain malignant potential SOX2 SREBP-1 targeted therapy TAZ TGF-? therapy transforming growth factor-? tumor tumor microenvironment tumor necrosis factor ? tumor stiffness type I collagen uterine fibroid Wnt YAP |
| ISBN | 3-03921-707-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Links between Fibrogenesis and Cancer |
| Record Nr. | UNINA-9910367745903321 |
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Gabazza Esteban C
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transcriptional Regulation of Cardiac Development and Disease
| Transcriptional Regulation of Cardiac Development and Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (222 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research & information: general |
| Soggetto non controllato |
apoptosis
arrhythmogenic cardiomyopathy (ACM) atomic force microscopy (AFM) Bmp signaling cardiac cell fate cardiac development cardiac hypertrophy cardiac malformation cardiac mesenchymal stromal cell cardiac regeneration cardiac reprogramming cardiac tissue engineering cardiomyocyte cardiomyocyte differentiation cardiomyocytes cardiomyogenic differentiation cardiomyopathy cardiovascular diseases cell-cell adhesion coronary vessel formation epicardial derived cells (EPDCs) epicardium epithelial mesenchymal transition (EMT) gene expression and regulation gene therapy growth factors Hand1 heart heart development heart failure Hippo signaling histone deacetylase inhibitors human heart hydrogels innate immune responses lamin A/C left ventricular assist device mouse embryonic stem cells myocardial infarction n/a neonatal rat ventricular fibroblasts (NRVF) pluripotent stem cells reactive oxygen species regeneration reverse remodelling SH3BGR Smad SRF signaling TEAD1 therapeutic angiogenesis tissue maturation TLR4 Toll-like receptor transcriptional regulation translational studies tunneling nanotubes (TNT) Wilms' tumor suppressor 1 Wilms' tumor suppressor 1 (Wt1) YAP |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674017103321 |
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Wagner Nicole
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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