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Disease and the Hippo Pathway: Cellular and Molecular Mechanisms
| Disease and the Hippo Pathway: Cellular and Molecular Mechanisms |
| Autore | Hansen Carsten Gram |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (226 p.) |
| Soggetto non controllato |
STRIPAK
skin cancer Lats2 transcription myofibroblast epigenetic Hippo cancer immunity TAZ Taz TAZ (transcriptional co-activator with PDZ-binding motif) adaptive immunity fibroblasts innate immunity LATS MST (mammalian STE20-like protein kinase) phosphorylation stem cells wound healing signal transduction angiogenesis LATS1/2 EMT protein-protein interactions structure biology Hippo pathway hippo pathway autoimmunity Mps one binder YAP/TAZ GPCR fibrosis MST1/2 YAP (yes-associated protein) YAP Yap protein kinase LATS (large tumor suppressor kinase) peripheral nerve sheath tumor signal cross-talk stem cell skin development STK38 tumorigenesis NDR schwannoma G protein-coupled receptor anti-cancer therapy feedback loops vascular mimicry castration resistance chromatin Hippo signalling ECM MST prostate cancer TEAD cancer zebrafish |
| ISBN | 3-03921-777-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Disease and the Hippo Pathway |
| Record Nr. | UNINA-9910367742003321 |
Hansen Carsten Gram
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges
| Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges |
| Autore | Gabazza Esteban C |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (348 p.) |
| Soggetto non controllato |
bleomycin
regeneration antitumor efficacy lung cancer SOX2 leiomyosarcoma lung cancer (LC) nanoparticles cytokines hepatocellular carcinoma metabolic reprogramming hepatic stellate cells angiogenesis transforming growth factor-? anaplastic lymphoma kinase idiopathic pulmonary fibrosis growth factor pathogenesis cancer-associated fibroblasts fibrosis lipopolysaccharide DHA lncRNA SREBP-1 YAP protein S non-small cell lung cancer (NSCLC) omega-3 fatty acid inflammation metastasis clinical symptoms miRNA smooth muscle tumor of uncertain malignant potential Wnt interstitial fluid pressure heterogeneity hepatocytes myometrium tumor necrosis factor ? tumor tumor microenvironment extracellular matrix TAZ carcinogenesis cystic formation pulmonary fibrosis HBV cytokine genetic instability diagnosis EMT crizotinib Hippo pathway GPR120 marker HCV non-alcoholic steatohepatitis pathology common pathways apoptosis type I collagen GPR40 acute lung injury uterine fibroid renal injury pathophysiology reactive oxygen species immunohistochemistry SMAD butylidenephthalide leiomyoma cirrhosis Erk1/2 targeted therapy TGF-? mechanotransduction therapy breast cancer hepatocellular carcinoma (HCC) hepatic stellate cells (HSCs) idiopathic pulmonary fibrosis (IPF) cancer-associated fibroblasts (CAFs) cancer signal pathway tumor stiffness |
| ISBN | 3-03921-707-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Links between Fibrogenesis and Cancer |
| Record Nr. | UNINA-9910367745903321 |
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Gabazza Esteban C
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transcriptional Regulation of Cardiac Development and Disease
| Transcriptional Regulation of Cardiac Development and Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
pluripotent stem cells
cardiomyocytes cardiac tissue engineering human heart tissue maturation Wilms' tumor suppressor 1 cardiomyocyte differentiation mouse embryonic stem cells myocardial infarction YAP TEAD1 Toll-like receptor heart TLR4 cardiomyocyte innate immune responses Wilms' tumor suppressor 1 (Wt1) cardiac development coronary vessel formation transcriptional regulation cardiac malformation epicardium epicardial derived cells (EPDCs) epithelial mesenchymal transition (EMT) cardiac cell fate regeneration arrhythmogenic cardiomyopathy (ACM) lamin A/C atomic force microscopy (AFM) cell-cell adhesion neonatal rat ventricular fibroblasts (NRVF) tunneling nanotubes (TNT) gene therapy cardiovascular diseases cardiac regeneration cardiac reprogramming therapeutic angiogenesis growth factors reactive oxygen species apoptosis Bmp signaling Hand1 Smad heart development SH3BGR cardiac hypertrophy SRF signaling Hippo signaling cardiomyogenic differentiation cardiac mesenchymal stromal cell hydrogels histone deacetylase inhibitors translational studies gene expression and regulation cardiomyopathy heart failure reverse remodelling left ventricular assist device |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674017103321 |
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Wagner Nicole
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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