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Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches
| Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches |
| Autore | Jeon Byeong Hwa |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (368 p.) |
| Soggetto topico |
Biotechnology
Technology: general issues |
| Soggetto non controllato |
ADMA
aerobic exercise aldehyde dehydrogenase-2 angiogenesis APE1/Ref-1 ApoE knockout mouse arginine arginine paradox atherosclerosis atorvastatin BH4 blood pressure cardiovascular disease cardiovascular diseases cardiovascular risk factors chronic kidney disease chronic venous insufficiency CKD compound 9 COVID-19 CV risk diabetes dietary supplements dyslipidemia electronegative LDL electronegative low-density lipoprotein EndoMT endothelial cell endothelial cell dysfunction endothelial cells endothelial disfunction endothelial dysfunction endothelial to mesenchymal transition endothelium eNOS uncoupling epigenetic factors epigenetics essential hypertension galectin-3 glycated HDL glycated LDL glycated lipoproteins glycolysis healing heart failure HIF-1α high-fat diets hyperglycemia hyperphosphatemia hypertension inflammageing inflammation insulin resistance ischemia L-arginine L5 LDL LDL(-) LDL(−) lectin-like oxLDL receptor-1 low-level laser therapy LOX-1 lung disease macrophage polarity macrophages metabolism metformin molecular mechanisms MRI (magnetic resonance imaging) myocardial infarction n/a NADPH nargenicin A1 neurovascular disease neutrophil/lymphocyte ratio nitric oxide oxidative stress oxidized LDL oxLDL pathological angiogenesis PCSK9 peripheral artery disease phototherapy plaque burden prolyl oligopeptidase (POP) pulmonary fibrosis pulmonary hypertension serological biomarkers serum γ-glutamyltransferase subcellular localization TGF-β therapeutic approaches tumor microenvironment uremic toxins vascular calcification vascular disease vascular inflammation vascular smooth muscle cells vasoactive factors VCAM-1 VEGF VEGFR2 VSMCs |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Endothelial Dysfunction |
| Record Nr. | UNINA-9910566471803321 |
Jeon Byeong Hwa
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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