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In Silico Strategies for Prospective Drug Repositionings
| In Silico Strategies for Prospective Drug Repositionings |
| Autore | Udrescu Lucreția |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries Medicine and Nursing Manufacturing industries |
| Soggetto non controllato |
COVID-19
drug repurposing topological data analysis persistent Betti function SARS-CoV-2 network-based pharmacology combination therapy nucleoside GS-441524 fluoxetine synergy antidepressant natural compounds QSAR molecular docking drug repositioning UK Biobank vaccine LC-2/ad cell line drug discovery docking MM-GBSA calculation molecular dynamics cytotoxicity assay GWAS multiple sclerosis oxidative stress repurposing ADME-Tox bioinformatics complex network analysis modularity clustering ATC code hidradenitis suppurativa acne inversa transcriptome proteome comorbid disorder biomarker signaling pathway druggable gene drug-repositioning MEK inhibitor MM/GBSA Glide docking MD simulation MM/PBSA single-cell RNA sequencing pulmonary fibrosis biological networks p38α MAPK allosteric inhibitors in silico screening computer-aided drug discovery network analysis psychiatric disorders medications psychiatry mental disorders toxoplasmosis Toxoplasma gondii in vitro screening drug targets drug-disease interaction target-disease interaction DPP4 inhibitors lipid rafts |
| ISBN | 3-0365-6133-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639987703321 |
Udrescu Lucreția
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metal-Based Drugs: Past, Present and Future
| Metal-Based Drugs: Past, Present and Future |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (328 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
3D cell cultures
anti-bacterial compounds antibacterial activity antibiotics anticancer activity anticancer agents anticancer drugs antimicrobial activity antiparasitic apoptosis auxotrophy bioorganometallic biotin breast cancer cancer cancer research carbohydrates caspases chitosan chlorophyllides cis and trans-Pt(II) coordination complexes copper copper(II) complexes CuAAC reactions delivery electronic spectra fluoxetine HCl FTIR gabapentin gallium gold gold compounds green synthesis heterobimetallic complexes human foreskin fibroblasts interactions lanthanum liposomes loading efficacy major depressive disorder MCF-7 MDA-MB-231 metal complexes metal-based drugs microarray-based detection molecular docking nanoparticles NHC silver complexes NHCs properties oncology orphan tumors platinum platinum (II) complexes platinum (IV) complexes platinum compounds Pseudomonas alloputida resistance phenomena ROS Rubus ruthenium ruthenium(II)-arene complexes ruthenium(III) complexes serum proteins silver spectroscopic spectroscopy structure activity relationships (SAR) synergy targeting strategies TEM thermodynamic analysis toxicity Toxoplasma gondii transition metals zinc oxide π-acceptor complexes |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Metal-Based Drugs |
| Record Nr. | UNINA-9911053220603321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Parasites in the Tropic - A New Paradigm Shift
| Parasites in the Tropic - A New Paradigm Shift |
| Autore | Suleyman Yazar |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 online resource (84 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico |
Medicine
Medicine and Nursing |
| Soggetto non controllato |
animal
congenital toxoplasmosis Epidemiology Gene Expression Health hormone immune response novel drugs Toxoplasma gondii Trypanosoma brucei spp |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910227349603321 |
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Suleyman Yazar
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Parasites, Pussycats and Psychosis : The Unknown Dangers of Human Toxoplasmosis
| Parasites, Pussycats and Psychosis : The Unknown Dangers of Human Toxoplasmosis |
| Autore | Torrey E. Fuller |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cham, : Springer International Publishing AG, 2021 |
| Descrizione fisica | 1 online resource (150 p.) |
| Soggetto topico |
Medicine: general issues
Psychiatry Toxoplasmosi |
| Soggetto genere / forma | Llibres electrònics |
| Soggetto non controllato |
Open Access
zoonosis Toxoplasma gondii domestication madness |
| ISBN | 3-030-86811-7 |
| Classificazione | MED000000MED105000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Acknowledgments -- Contents -- About the Author -- Other Books by the Author -- 1: Psychosis as a Zoonosis: Clues from Covid -- 1.1 Diseases from Animals -- 1.2 Bats and Rats, but Please, Not Cats -- 1.3 The Origin of Cats -- 1.4 Infectious Agents and Psychosis -- References -- 2: The Case for Toxoplasma gondii in Psychosis and Other Human Diseases -- 2.1 Modes of Transmission -- 2.2 What Is Known Regarding Human Infections? -- 2.3 Fatal Attraction -- 2.4 What Is the Evidence for Toxoplasmosis and Psychosis? -- 2.4.1 T. gondii Can Cause Psychotic Symptoms -- 2.4.2 Among Individuals with Schizophrenia, Those Who Are Infected with T. gondii Have Been Shown to Have More Severe Symptoms -- 2.4.3 Individuals with Psychosis, Compared to Controls, Are Significantly More Likely to Have Antibodies Against T. gondii, Indicating Past Infection -- 2.4.4 Individuals with Schizophrenia or Bipolar Disorder, Compared to Controls, Are Significantly More Likely as a Child to Have Lived in a Home with a Cat -- 2.5 How Many Cases of Psychosis Might Be Caused by T. gondii? -- 2.6 Other Diseases and Conditions -- References -- 3: The Rise of Cats and Madness: I. The Renaissance -- 3.1 Cats and Satan -- 3.2 Cats During the Renaissance -- 3.3 The Beginning of Cat Rehabilitation -- 3.4 Madness in the Renaissance -- References -- 4: The Rise of Cats and Madness: II. The Seventeenth and Eighteenth Centuries -- 4.1 The Continuing Persecution of Cats -- 4.2 Pet Keeping Becomes More Popular -- 4.3 Cats as Pets -- 4.4 Increasing Interest in Madness -- 4.5 Bethlem as a Human Zoo -- 4.6 Was Madness Increasing? -- 4.7 Cats in Eighteenth Century England -- 4.8 Cats in Art and Poetry -- 4.9 Hospitals for Mad Persons -- 4.10 Public Interest in Madness -- 4.11 Mad Poets -- 4.12 The English Malady -- References.
5: The Rise of Cats and Madness: III. The Nineteenth Century -- 5.1 The King's Madness -- 5.2 Nineteenth-Century Cats -- 5.3 The Cats of Writers and Artists -- 5.4 Increasing Insanity -- 5.5 What Was Causing the Increase? -- 5.6 Madness Among "the Better Sort" -- 5.7 Was Insanity Really Increasing? -- 5.8 Official Denial of the Problem -- 5.9 The Debate Winds Down -- References -- 6: Additional Links Between Toxoplasmosis and Psychosis -- 6.1 Survey of the Historical Data -- 6.2 Fewer Cats, Less Psychosis? -- 6.3 More Toxoplasmosis, More Psychosis? -- 6.4 Seasonality of Birth -- 6.5 Urban Living in Childhood -- 6.6 More Psychosis Where It's Colder -- 6.7 The Immigrant Issue -- 6.8 Isn't Schizophrenia Genetic? -- 6.9 Why Isn't There More Psychosis? -- References -- 7: Sentinel Seals, Safe Cats, and Better Treatments -- 7.1 A Review -- 7.2 What Is the Magnitude of the Problem? -- 7.3 Oocyst Contamination of Soil and Water -- 7.4 Solutions to the Problem -- 7.4.1 Decrease the Distribution of Infective T. gondii Oocysts -- 7.4.2 Research -- 7.4.3 Better Treatments -- 7.4.4 Education -- References -- Index. |
| Record Nr. | UNINA-9910510568203321 |
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Torrey E. Fuller
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| Cham, : Springer International Publishing AG, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Study of Microbiological Safety in the Food Chain
| Study of Microbiological Safety in the Food Chain |
| Autore | Zdolec Nevijo |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (140 p.) |
| Soggetto topico |
Humanities
Social interaction History Social and ethical issues |
| Soggetto non controllato |
antimicrobial resistance
Aspergillus Bacillus bacteriocins biogenic amines biological hazards Cladosporium colony morphology creatine Croatian regions dry aged beef dry-cured hams egg egg quality Ehrlich reaction emerging foodborne pathogens enterococcal species enterococci ewe food chain information Fusarium index lactobacilli Lactobacillus johnsonii Lactobacillus zeae lactococci MALDI-TOF-MS meat products meat safety microbial flora microbiome milk milk lump cheese mold n/a PCR PCR-ITS-RFLP Penicillium probiotics rancidity raw goat milk restriction enzyme ripened cheese safety sensory evaluation surface moulds Toxoplasma gondii virulence factor Yersinia enterocolitica |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566465003321 |
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Zdolec Nevijo
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxoplasma gondii Host Interactions: A Story of Immune Attack and Parasite Counterattack
| Toxoplasma gondii Host Interactions: A Story of Immune Attack and Parasite Counterattack |
| Autore | Saeij Jeroen P. J |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (233 p.) |
| Soggetto topico |
Infectious and contagious diseases
Science: general issues |
| Soggetto non controllato |
Host-Parasite Interactions
Immune Response Innate Immunity Secreted Effectors Toxoplasma gondii |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Toxoplasma gondii Host Interactions |
| Record Nr. | UNINA-9910557260103321 |
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Saeij Jeroen P. J
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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