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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (480 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
12-deacetyl-12-epi-scalaradial
3-alkylpyridinium polymers A375 and HeLa cell lines A549 cells ABC transporter actinomycin AD0157 adriamycin resistance Aeroplysinin Akt angiogenesis angiogenesis inhibitor ansamycins anthranilic acid anti-angiogenesis anti-angiogenic anti-cancer anti-metastatic activity anti-proliferation anti-proliferative antiangiogenesis antiangiogenic antibacterial Antibody Drug Conjugates (ADCs) anticancer anticancer activity anticancer agent anticancer immunity anticarcinogenic anticoagulant anticoagulation antifouling Antimicrobial peptide (AMP) antioxidant antiproliferative antiproliferative activity antitumor antitumor activities antitumoral antitumour AP-1 apoptosis apoptosis-inducing activity approved antitumor agents araguspongine C arrest of cell cycle Aspergillus autophagy autophagy inducers autophagy inhibitors azoxymethane BCRP/ABCG2 BEL-7402 cell benzo[a]pyrene bioactive natural product bioanalysis bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) bonnethead shark breast cancer breast cancer cells Brevianamide brominated indoles bromophenol buccal gland c-JUN c-Met C15 acetogenins camptothecin cancer Cancer cancer genes cancer preventive cancer progression Cantabrian Sea-derived actinobacteria carbocyclic analogue carcinoembryonic antigen Caribbean sponge carotenoid carotenoids caspase cascade cell adhesion cell adhesion molecules cell cycle cell cycle arrest cell migration cembranoids chemical conjugation chemoprevention chemopreventive chemosensitization chemotherapy chimera CHOP chromatography circulating tumor cells cisplatin clinical trials colorectal cancer cooperative binding cyclin D1 cyclin-dependent kinase CYP1A1 cystatin F cystatin superfamily cytokine release cytoskeleton cytotoxic activity cytotoxicity deep-sea depolymerisation dibromotyrosine dieckol divergolides DNA minor groove binder drug discovery Ecklonia cava elisidepsin EMT endoperoxide endophytic fungus endothelial cells energy stress epigonal organ epithelial-mesenchymal transition ER-stress ET-743 evolution FAK fascaplysin fatty acid 2-hydroxylase fatty acids FAU FBDD fucoidan fucoxanthin fumigaclavine C gemcitabine gene expression glioblastoma gliotoxin glucocorticoid receptor glycosaminoglycans gorgonian Haliclona gracilis HeLa cells heparan sulphate heparanase hepatocellular carcinoma HER2 HIF-1 hippuristanol HSP90 human lung cancer human normal diploid fibroblast (TIG-1 cells) human sarcoma cell line (HT1080 cells) humulane sesquiterpenoids hybridization hydroxylated lipids hypoxia hypoxia-inducible factor-1 IL-6 in vivo model inflammation inhibitor integrin β1 invasion isatin Isofistularin itampolin A jaspine B JNK1/2 Jurkat kalkitoxin kunitz type inhibitor Lampetra morii Leathesia nana Leptogorgia leukemia lipid rafts low molecular weight fucoidan extract low toxic LS-1 lung cancer lung metastasis Lyngbya majuscula macrolide mangrove-derived actinomycete manzamine A MAPK/ERK pathway marangucyclines marine antitumor agents marine biotechnology marine compound marine drug marine drugs marine fungus marine metabolites marine mollusc marine natural products marine organisms marine sponges marine-derived drugs Marthasterias glacialis L. MCP-1 mechanisms of action melanoma membrane permeabilization metastasis microalgae Micromonospora migration mitochondria mitochondria toxin mitochondrial pathway mitochondrial dysfunction molecular docking molecular mechanisms molecular modeling molecular oncology Moorea producens MRP1/ABCC1 multi-drug resistant leukemia multidrug resistance Mycalin A Mycochromenic acid derivative N-Ras n/a nanoparticle naphthopyrones natural marine compounds natural product natural products neuroblastoma-rat sarcoma NF-κB NF-κB signaling nicotine nicotinic acetylcholine receptor non-small cell lung cancer non-small cell lung cancer (NSCLC) non-small cell lung carcinoma nonfunctioning pituitary adenomas novel inhibitor NSCLC Nur77 osteosarcoma oxidative stress oxidative stress P-gp/ABCB1 P2X7 receptor p38 p38/ERK p38α p65 pachastrissamine palmitic acid paulomycins pazopanib PEL Penicillium brevicompactum Penicillium paneum phase I pheochromocytoma and paraganglioma phlorotannins phycocyanin PI3K/Akt plakortide plitidepsin pollution poly(ADP-ribose)-polymerase inhibitor polyoxygenated steroids polyphenols polysaccharides Porifera porifera/sponge preclinical programmed cell death programmed cell death-ligand 1 programmed cell death-ligand 2 proliferation prostate cancer proteasomal degradation proteomic pseudopterosin puupehenones pyrrolidinedione reactive oxygen species RGD motif ribosomal protein genes ROS RPS30 safety Sarcophyton ehrenbergi sea anemone sea cucumbers seaweed secondary metabolites sediment selenium-containing polysaccharide-protein complex Sepia ink polysaccharides shrimp signal transduction sinulariolide sipholenol A small cell lung cancer SNORA62 snoRNA SNU-C5/5-FU soft coral soft tissue sarcoma soft tissue sarcoma sphingosine kinase inhibitor sponge sponges STAT3 Streptomyces sp. SCSIO 11594 synergism synthetic analogues SZ-685C targeted therapy terpenes tetracenomycin X TGF-β signaling Thalassia testudinum thalassiolin B therapeutic compounds Tilapia piscidin 4 (TP4) TNFα Topo I inhibitor topoisomerase trabectedin triterpene glycosides TRPM7 tumor cell line tumor microenvironment tumor-associated macrophages Ulva fasciata uveal melanoma VEGF virtual screening xyloketal B α9-nicotinic acetylcholine receptors (nAChRs) αO-conotoxin GeXIVA β1-integrin λ-carrageenan |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Rheumatoid Arthritis Therapy Reappraisal : Strategies, Opportunities and Challenges
| Rheumatoid Arthritis Therapy Reappraisal : Strategies, Opportunities and Challenges |
| Autore | Müller Rüdiger |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (260 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
ACR response
adenosine ankylosing spondylitis anti-citrullinated protein autoantibodies anti-TNF baricitinib bioavailability biosimilar certolizumab pegol computed tomography csDMARDs cytokine DAS 28 disease-modifying antirheumatic drugs DMARD effectiveness efficacy fatigue foot fracture fracture risk assessment tool glucocorticoids golimumab hand HAQ-DI herbal medicine IFN-γ, CD73 IL-17A immunogenicity infliximab intra-articular injections magnetic resonance imaging matrix metalloproteinase 3 medication methotrexate methylation MTX n/a next-generation sequencing oral oral route osteoclast osteoporosis outcomes research pain pain perception patient perspective periodontal disease periodontitis personalized medicine pharmacogenomics Porphyromonas gingivalis posology productivity pseudoerosions psoriatic arthritis radiography recovery of function regulation rheumatoid arthritis Rheumatoid arthritis Rheumatoid Arthritis rheumatoid factor sleep sleep disorders smoking subcutaneous route switching synovial fibroblasts Th1.17 therapy titration TNFα tofacitinib tolerability treat-to-target Tumor Necrosis Factor-Alpha Inhibitors ultrasonography |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Rheumatoid Arthritis Therapy Reappraisal |
| Record Nr. | UNINA-9910557286503321 |
|
Müller Rüdiger
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
|
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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