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Advances in Nanomaterials in Biomedicine
| Advances in Nanomaterials in Biomedicine |
| Autore | Ryabchikova Elena I |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (472 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
bone marrow-derived mesenchymal stromal cells
rAAV vectors carbon dots SOX9 TGF-β cartilage repair silver nanoparticles Entada spiralis Ceiba pentandra antibacterial assay catalytic dye reduction osteoarthritis human articular cartilage polymeric micelles pro-inflammatory cytokines IL-1β TNF-α nanomaterials nanomedicine immunotherapy oncotherapy immune-checkpoint inhibitors immunogenic cell death nano-vaccines nano-conjugates immune response oxidative stress antioxidants nanoparticles biological nano-antioxidants gold nanoparticles radiation chemotherapy radiosensitizer drug delivery system chemoradiotherapy magnetoliposomes hydrogels magnetolipogels self-assembly fluorescence Förster resonance energy transfer polypropylenimine dendrimers polyethylenimines tyrosine-modified polypropylene-imines tyrosine-modified polyethlyenimines PPI-Y siRNA transfection polymeric nanoparticles carbosilane dendron triazine amphiphile vesicles pH-sensitive doxorubicin methotrexate leukaemia molecular ultrasound nanobubbles active targeting targeted microbubbles angiogenesis inflammation thrombosis clinical translation molecular imaging liver fibrosis diagnosis therapy theranostics targeted drug delivery lipid conjugates amphiphilic oligonucleotides phosphoryl guanidines nucleic acid delivery leukemia iron nanoparticles RNA-Seq cytotoxicity polymers biodegradable drug delivery pharmaceutical SQUID magnetic properties iron content magnetite nanoparticles superoxide aorta heart nano-biomaterials nanotechnology scaffolds hard tissue engineering AuNPs AuPEI-NPs AuBSA-NPs electron microscopy ultrastructure of HepG2 cells and spheroids ultrastructure of HEK293 cells and spheroids penetration of NPs into monolayer and spheroids gold nanostars photothermal therapy photoacoustic imaging computed tomography cancer theranostic agents biocompatible nanomaterials diagnostics nanocarriers tissue engineering |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557724003321 |
Ryabchikova Elena I
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches
| Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches |
| Autore | Jeon Byeong Hwa |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico |
Technology: general issues
Biotechnology |
| Soggetto non controllato |
endothelial cells
oxidative stress inflammageing endothelial dysfunction aldehyde dehydrogenase-2 cardiovascular disease neurovascular disease vascular inflammation APE1/Ref-1 cardiovascular diseases subcellular localization serological biomarkers atherosclerosis aerobic exercise PCSK9 LOX-1 insulin resistance macrophage polarity serum γ-glutamyltransferase essential hypertension cardiovascular risk factors angiogenesis nargenicin A1 compound 9 VEGF VEGFR2 HIF-1α electronegative low-density lipoprotein LDL(-) L5 LDL oxidized LDL oxLDL ADMA arginine arginine paradox BH4 blood pressure COVID-19 dietary supplements endothelium eNOS uncoupling heart failure hypertension L-arginine myocardial infarction NADPH nitric oxide peripheral artery disease ApoE knockout mouse atorvastatin VCAM-1 galectin-3 neutrophil/lymphocyte ratio electronegative LDL LDL(−) lectin-like oxLDL receptor-1 dyslipidemia chronic venous insufficiency prolyl oligopeptidase (POP) inflammation endothelial disfunction lung disease endothelial to mesenchymal transition pulmonary hypertension pulmonary fibrosis metformin diabetes CV risk hyperglycemia glycated lipoproteins glycated LDL glycated HDL endothelial cell dysfunction molecular mechanisms epigenetic factors therapeutic approaches vasoactive factors EndoMT TGF-β epigenetics endothelial cell glycolysis metabolism pathological angiogenesis tumor microenvironment MRI (magnetic resonance imaging) high-fat diets plaque burden low-level laser therapy phototherapy vascular disease healing ischemia vascular calcification chronic kidney disease CKD uremic toxins hyperphosphatemia vascular smooth muscle cells VSMCs macrophages |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Endothelial Dysfunction |
| Record Nr. | UNINA-9910566471803321 |
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Jeon Byeong Hwa
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers
| Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers |
| Autore | Kutner Andrzej |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (450 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
alpha-ketoglutarate
cell cycle apoptosis JNK cell migration cell invasion TGF-β VEGF glycoconjugates methotrexate cancer treatment glucose metabolism drug design and discovery anticancer drugs targeted therapy Warburg effect antidepressants pyrido[1,2-c]pyrimidines dual 5-HT1A/SERT activity drug design anticancer activity lung cancer resveratrol PRI-2191 vitamin D active substance delivery systems biomedical hydrogels active substance-controlled release genistein hydrogels for cosmetology hydrogels for dermatology transdermal active substance delivery systems histone deacetylase (HDAC) depression biomarker anti-depressant therapy human DNA topoisomerase cancer drug molecular docking synthesis fluorine vitamin D3 metabolite A-ring CD-ring side-chain nanoparticles molecular modeling oxidation mechanisms electrochemistry MALDI spectroscopic data cytotoxic study self-assembled monolayer gold electrode multimodal activity calcium-sensing receptor enantiomer calcimimetic calcilytic colon cancer stereospecificity HT-29 IL-8 inflammation cyclooxygenase 1,2,4-triazole pyridazinone SAR anti-inflammatory activity antioxidant activity ADME anticancer drug antimicrobial peptide (AMP) dermaseptin frog skin peptides LHRH prostate cancer Phyllomedusa bicolor therapeutic peptides copper (II) complexes thiourea cytotoxic activity proteome analysis antimicrobial activity major latex protein Chelidonium majus greater celandine defense-related proteins alkaloids cancer cells vitamin D receptor split luciferase-based biosensor CYP24A1-dependent metabolism CYP27B1 rickets genome editing vitamin D biology and action transcription ChIP-chip analysis distal enhancers histone H3 acetylation RNA polymerase II analogue actions at genes vitamin D hormone (1,25(OH)2D3) latex antiviral proteins antimicrobial compounds cytotoxicity drug discovery CRISPR/Cas9 tetrahydro-β-carbolines Plasmodium falciparum (P. falciparum) antimalarial antiparasitic agents hemolysis vitamin D analogs 25 vitamin D 24-hydroxylase CYP24A1 proliferation high-grade serous ovarian cancer cells gold Au(III) complex colorectal cancer organometallic cancer therapy metallodrugs |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585938903321 |
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Kutner Andrzej
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Osteoarthritis: From Molecular Pathways to Therapeutic Advances
| Osteoarthritis: From Molecular Pathways to Therapeutic Advances |
| Autore | Veronese Nicola |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (306 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
osteoarthritis
cartilage type II collagen matrix metalloproteinases MMP-13 regulation inhibitor NO synthase Interleukin-1β chondrocytes mitochondrial dysfunction mesenchimal stem cells chondrocytic commitment autophagy miRNAs hydrostatic pressure adipokines visfatin Wnt/β-catenin mechanical loading obesity microRNA oxidative stress vibrational spectroscopy near-infrared spectroscopy infrared spectroscopy Raman spectroscopy early diagnosis exercise physical activity nutraceuticals dietary supplements inflammation aging inflammaging osteochondral explant culture joint modelling pharmacological assay native tissue analysis hexosamine biosynthetic pathway cartilage trauma post-traumatic osteoarthritis O-GlcNAcylation glucosamine cell death therapy sex as a biological variable whole transcriptome sequencing molecules TGF-β SMAD2/3 signaling linker modifications meniscus proteomics MRM ECM celecoxib glucosamine sulfate chondroprotection NF-κB cytokines chemokines pathogenesis biomarker chondrocyte IL-1β IFNγ, IL-17 IL-4 RNA-Seq hypertrophy remodeling angiogenesis chondroitin collagen methylsulfonylmethane vitamin C vitamin D hyaluronic acid |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Osteoarthritis |
| Record Nr. | UNINA-9910566461503321 |
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Veronese Nicola
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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