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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (418 p.) |
| Soggetto topico | Biotechnology |
| Soggetto non controllato |
activation induced deaminase
AID/APOBEC alternative splicing anti-cancer artificial intelligence bioinformatics Bioinformatics tool biomarker discovery biomarker signature biomarkers biostatistics brain brain metastases breast cancer breast cancer detection breast cancer prognosis Bufadienolide-like chemicals cancer cancer biomarker cancer biomarkers cancer CRISPR cancer modeling cancer prognosis cancer treatment cancer-related pathways cell-free DNA chemotherapy circulating tumor DNA (ctDNA) classification clinical/environmental factors colorectal cancer comorbidity score Computational Immunology concatenated deep feature copy number aberration copy number variation curation curative surgery datasets decision support systems deep learning denoising autoencoders differential gene expression analysis diseases genes DNA DNA sequence profile drug resistance epigenetics erlotinib estrogen extreme learning false discovery rate feature extraction and interpretation feature selection firehose functional analysis gefitinib gene expression analysis gene inactivation biomarkers gene loss biomarkers gene signature extraction genomic instability GEO DataSets head and neck cancer health strengthening herb hierarchical clustering analysis high-throughput analysis histopathological imaging histopathological imaging features HNSCC hormone sensitive cancers HP hTERT imaging independent prognostic power interaction intratumor heterogeneity knockoffs KRAS mutation locoregionally advanced machine learning meta-analysis methylation microarray miRNA miRNAs mitochondrial metabolism mixture of normal distributions molecular mechanism molecular subtypes Monte Carlo mortality multiple-biomarkers mutable motif mutation Neoantigen Prediction network analysis Network Analysis network pharmacology network target neurological disorders next generation sequencing observed survival interval omics omics profiles oral cancer ovarian cancer overall survival pancreatic cancer pathophysiology PD-L1 precision medicine predictive model protein R package RNA self-organizing map single-biomarkers single-cell sequencing skin cutaneous melanoma somatic mutation StAR steroidogenic enzymes survival analysis TCGA TCGA mining telomerase telomeres The Cancer Genome Atlas traditional Chinese medicine transcriptional signatures treatment de-escalation tumor tumor infiltrating lymphocytes tumor microenvironment variable selection |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioinformatics Tools (and Web Server) for Cancer Biomarker Development
| Bioinformatics Tools (and Web Server) for Cancer Biomarker Development |
| Autore | Guo Xiangqian |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (197 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
bioinformatics
biomarker GEO prognostic RNA sequence TCGA webserver |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Bioinformatics Tools |
| Record Nr. | UNINA-9910557492403321 |
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Guo Xiangqian
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations
| Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations |
| Autore | Ciarimboli Giuliano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (248 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
anticholinergics
antidepressant-like activity Baricitinib bile acids chronic kidney disease chronic lung diseases chronoamperometry cisplatin nephrotoxicity drug disposition drug excretion drug transport drug transporters drug uptake drug-induced kidney injury drugs endogenous metabolism forced swim test functional subgroups gene ontology genetic polymorphisms gut microbiome hepatotoxicity human pathology atlas interorgan communication isoflurane ketamine kidney kidneys lung epithelium Malpighian tubule MATE MATE1 n/a nephrotoxicity Nuclear receptor OCT OCT1 organic anion transporter organic cation transporter organic cation transporters organic cations organic transporters pesticides plasma membrane monoamine transporter PPAR-alpha pulmonary drug delivery RA regulation remote sensing and signaling Remote Sensing and Signaling Theory renal excretion serotonin clearance serotonin transporter SLC22 SLC22A1 SLC22A1-5 SLC22A15 SLC22A16 SLC22A18 solute carrier solute carrier (SLC) family solute carrier 22 (SLC22) species differences tail suspension test TCGA Tofacitinib transport transporters trospium β2-agonists |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557346203321 |
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Ciarimboli Giuliano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments in Cancer Systems Biology
| Recent Developments in Cancer Systems Biology |
| Autore | Sinha Raghu |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (272 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acute myeloid leukemia
bioinformatics biomarker Boolean model brain-tumor-initiating cell (BTIC) breast cancer cancer genomics cancer progression cancer stem cells cancer systems biology circulating miR-1246 clinical trials CNV computational methods diagnostic biomarker differential expression docking drug repurposing drug resistance Elk-1 Ets ETS Ets-1 experimental model systems genomics glioma glycomics glycosaminoglycan binding knockdown lung adenocarcinoma lung adenocarcinoma (LUAD) lung cancer lung squamous cell carcinoma (LUSC) metabolomics metagenomics microarray n/a network next-generation sequencing non-small-cell lung cancer omics optical genome mapping ovarian pancreatic cancer patient survival patient-derived organoids patient-derived xenografts PEA3 personalized medicine PI3K-Akt signaling pathways prognosis prognostic biomarker protein interactome proteomics renal cancers risk group Sestrin2 signature single-cell sequencing SNV solid tumors stem cell survival systems biology TargetScan TCGA transcriptomics triple-negative breast cancer UBE2C virtual screening |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557768503321 |
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Sinha Raghu
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Renal Cell Carcinoma
| Renal Cell Carcinoma |
| Autore | López José I |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (500 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
11) translocation renal cell carcinoma
ALK AMP-activated protein kinases anaplastic lymphoma kinase rearrangement aurora A biomarker cancer immunotherapy cancer-specific survival CDKN1A expression checkpoint inhibitors chromophobe renal cell carcinoma chromosomal loss chronic kidney disease circular RNAs in a clinico-genomic predictive model clear cell renal cell carcinoma clear cell Renal Cell Carcinoma collecting duct carcinoma copy number alteration copy number analysis copy number loss curcumin cytoreductive nephrectomy diagnostic and prognostic markers drug sensitivity efficacy emerging entity EMT like eosinophilic variant ESC everolimus EVI1 experimental validation of circular RNA FISH FOXO3 gene expression gene signature genetic association ghrelin glutathione metabolism glutathione transferase omega 1 glutathione transferase omega 2 glycomarkers glycoproteomics HOT hyperosmolality identification of circular RNAs IL-1? IL-2 IL13R?1 IL4R? immune checkpoint inhibitors immune infiltration immunohistochemistry immunotherapy inflammation markers integrins intratumour heterogeneity invasion JAK2 kidney kidney cancer label-free LOT metabolic reprogramming metabolome metabolome profiling metastasis metastatic ccRCC microRNA miR-133b miR-146a-5p miR-155-5p MiT family translocation renal cell carcinoma MMP-9 MMP10 molecular genetic features MTA2 mTOR mTOR inhibitors mutation N-glycomapping n/a nephrectomy new entity NK cells oncocytic renal tumor overall survival pale cell Papillary renal cell carcinoma (pRCC) patient survival PBRM1 PD-L1 pentose phosphate pathway PI3K/Akt/mTOR polybromo-1 polymorphism PPP practical approach predictive factors predictive role pro-IL-1? prognosis prognostic factors programmed death-ligand 1 proliferation proteome profiling Raf/MEK/ERK RCC recurrence free survival recurrence-free survival renal cancer renal cell renal cell cancer renal cell carcinoma review RNA sequencing sarcomatoid SMAD proteins solute carrier proteins statins survival survival prediction t(6 targeted therapy TCA cycle TCGA TFE3 TFEB TFEB-amplified renal cell carcinoma toxicity transforming growth factor beta tumor adhesion tumor microenvironment tumor migration tumor slice culture tyrosine kinase inhibitors unclassified renal cell carcinoma unclassified renal tumor uric acid urine VEGF inhibitors von Hippel-Lindau Xp11 translocation renal cell carcinoma |
| ISBN | 3-03928-639-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087003321 |
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López José I
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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