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Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (358 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
(−)-N-phenethylnorhydromorphone analogs
[35S]GTPgammaS assay [Dmt1]DALDA 14-methoxycodeine-6-O-sulfate 1H-NMR experiments 6β-naltrexol abuse agonist allodynia analgesia analgesics antagonist arrestin recruitment beta-arrestin bias factor biased agonism biased agonist biased agonists biased ligands biased signaling bifunctional ligands binding binding affinity BNTX buprenorphine chronic constriction injury (CCI) codeine codeine-6-O-sulfate DADLE DALDA DAMGO delta opioid receptor dependence design and synthesis dihydrocodeine diphenethylamines docking dysbiosis fentanyl forskolin-induced cAMP accumulation assays functional assay G-protein bias heteromer hyperalgesia interaction fingerprints internalization inverse agonist ischemia kappa opioid receptor KGOP01 Leu-enkephalin loperamide lysosomes macrocyclic tetrapeptide mechanism elucidation misuse mitragynine molecular docking molecular dynamics molecular modeling & MOR and DOR agonists morphinan morphine mu opioid receptor mu receptor multifunctional ligands n/a naltrexone neonatal opioid withdrawal syndrome neurokinin-1 receptor neutral antagonist NTI derivative opioid opioid drugs opioid liabilities opioid peptide opioid peptides opioid peptides and peptidomimetics opioid receptors opioid side effects opioids over-the-counter drugs pain therapy partial agonism partial agonist peptide synthesis peripheral analgesic tolerance peripheral antinociception peripheral µ-opioid receptors pharmacology plasma stability potassium channels primary hippocampal culture PZM21 racemic synthesis of β2-amino acids receptor binding studies receptor model respiration respiratory depression selectivity simulation SR-17018 structure-activity relationships sulfonamide TAPP tolerance writhing test zerumbone β-arrestin recruitment assays β2-amino acids β2-Homo-amino acids δ opioid receptor δ opioid receptor antagonist μ opioid receptor µ opioid receptor µ-opioid receptor |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910557108003321 |
Spetea Mariana
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances in Minimally Invasive Surgery
| Recent Advances in Minimally Invasive Surgery |
| Autore | Biebl Matthias |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (414 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
3D printing
anesthetics anti-Müllerian hormone artificial intelligence augmented reality autonomic pelvic nerves biliopancreatic diversion body donors cervical cancer cholangiocarcinoma chronic pelvic pain clinical anatomy colorectal liver metastases conversion rate counseling COVID-19 cysts of the canal of Nuck da Vinci diaphragmatic hernia embryologic development embryology endometrial cancer endometrial neoplasms endometrioma surgery endometriosis endoscopic surgery endoscopy enterothorax esophageal cancer esophagectomy fetal surgery general anesthesia genital nerves stimulation gynecology health-related quality of life hepatectomy hepatic metastasis hepatocellular cancer hepatocellular carcinoma hernia repair hydrocelectomy hysterectomy hysteroscopy indocyanine green intercostal catheter intraoperative imaging Ivor-Lewis procedure laparoscopic laparoscopic hysterectomy laparoscopic liver surgery laparoscopic repair laparoscopic surgery laparoscopy learning curve Lichtenstein LION procedure live surgery events liver resection local recurrence lung cancer lymphadenectomy machine learning malabsorption mesh mesh use mesorectal meta-analysis minimal invasive surgery minimally invasive minimally invasive surgery minimally invasive surgical procedures mortality n/a native tissue neuropelveology NOTES Nuck hydrocele oncologic surgery one-anastomosis gastric bypass open surgery opioid ovarian cancer ovarian neoplasms ovarian reserve pain pancreatic surgery pancreaticoduodenectomy patient-doctor-relationship pectopexy pediatric surgery pelvic compartments pelvic floor pelvic floor repair pelvic lymphonodectomy pelvitrainer perioperative care platelet-rich plasma (PRP) PMMR postoperative pain control prolapse prostate cancer quality of life radiofrequency pre-coagulation radiotherapy real-life imaging rectal cancer recurrence rate regional anaesthesia risk score robotic assisted surgery robotic liver resection robotic radical hysterectomy robotic surgery Roux-en-Y gastric bypass SADI-S sars-cov-2 sentinel lymph node mapping sexuality single-incision surgery single-port laparoscopy skill assessment snorkel mask spontaneous pregnancy surgery surgical devices surgical education surgical performance surgical techniques surgical training survival survival analysis systematic review TAPP technical aspects thin endometrium thoracic surgery topographic anatomy transanal uterine cancer uterine cervical neoplasms vaginal neoplasms vaginal repair VATS video feedback video modeling vulvar neoplasms weight regain |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557467203321 |
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Biebl Matthias
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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