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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological and Pharmacological Activity of Plant Natural Compounds II
| Biological and Pharmacological Activity of Plant Natural Compounds II |
| Autore | Pezzani Raffaele |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (338 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
Bergenia species
botanical description traditional uses phytochemistry pharmacology anti-urolithiatic activity bergenin Flaxseed oil linusorb B3 anti-cancer apoptosis actin polymerization Src glioblastoma chlorogenic acid coffee cyclooxygenase espresso instant coffee platelet aggregation Rubia tinctorum L. antioxidants polyphenols ethylene glycol urolithiasis histophatology Saccharomyces cerevisiae β-glucan antimicrobial and anticancer activities detoxification ability immunomodulatory effect Aquilaria sinensis pheophorbide A MMP-2 MMP-9 HT-1080 advanced glycation end product (AGE) oxidative stress epithelial to mesenchymal transition AGE-inhibitor swertiamarin diabetic nephropathy astragaloside IV Astragalus membranaceus huang qi Astragali Radix liver liver regeneration 70% partial hepatectomy proliferation rat memory object recognition Ginkgo biloba dorsal hippocampus formation brain-derived neurotrophic factor Diclofenac γ-lactone nano-emulsion methylcellulose Ostrich oil Struthio camelus Caenorhabditis elegans leaf extract neuroprotection antioxidant activity DAF-16 Clerodendrum infortunatum terpenoids phenylpropanoids antidiabetic breast cancer Combretum indicum L. antidiabetic activity histopathology UPLC-QTOF/ESI-MS network pharmacology Biebersteinia heterostemon galegine hypotensive toxicity Sage Salvia officinalis cytotoxicity hepatoprotection MDA TAOxC MCF-7 HeLA cells HepG-2 cells Peganum harmala anti-inflammatory activity antioxidant LC-ESI-MS/MS traditional medicine rheumatoid arthritis rosmanol carnosol Callicarpa longissima TLR4/NF-κB/MAPK synergistic effect diabetes mellitus anti-diabetic drugs monoterpenes |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566486603321 |
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Pezzani Raffaele
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery
| Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery |
| Autore | Hussain Hidayat |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (360 p.) |
| Soggetto topico |
Research & information: general
Chemistry Organic chemistry |
| Soggetto non controllato |
multi-component reaction
fusidic acid TEMPO-conjugate electron paramagnetic resonance (EPR) spectroscopy caspase-3 incomptine A sesquiterpene lactone Decachaeta incompta cytotoxic activity iTRAQ apoptosis ROS production violacein hepatocellular carcinoma proliferation stemness natural products tumor microenvironment (TME) lung cancer phytochemicals botanical agents steroidal alkaloids solanidane alkaloids demissidine solanidine flavonoids coronavirus SARS-CoV-2 SARS-CoV MERS-CoV anticancer activity apoptosis resistance ophiobolin A polygodial Wittig reaction melanoma tumor heterogeneity pregnancy anti-tumor peptides in vitro model medicinal herbs cancer treatment cancer stem cells drug resistance metastasis RCE-4 PCD ATG 4B the Bcl-2-Beclin 1 complex Sparticola junci structure elucidation ECD-TDDFT COX inhibitory molecular docking antiproliferative cytotoxic Sepedonium ampullosporum peptaibols ampullosporin glutamic acid methyl ester solid-phase peptide synthesis antifungal anticancer target identification kaempferol docking DARTS Src breast cancer butein frondoside-A STAT3 angiogenesis invasion viability tumor growth marine fungi Cosmospora sp soudanone Magnaporthe oryzae co-culture phytopathogen molecular networking metabolomics bispecific antibody Trypsiligase click chemistry biorthogonal chemistry antibody engineering |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday |
| Record Nr. | UNINA-9910585945403321 |
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Hussain Hidayat
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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