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Protein-Ligand Interactions: Target Identification and Drug Discovery
| Protein-Ligand Interactions: Target Identification and Drug Discovery |
| Autore | Altieri Fabio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (184 p.) |
| Soggetto topico |
Chemistry
Research and information: general |
| Soggetto non controllato |
ACE
acetylcholinesterase amyloid beta aggregation brassicasterol cancer cell death cell viability CoCl2 drug development drug discovery endocrine disruptor compound fatty acid conjugation FcRn-mediated recycling fluorescence spectroscopy GADD45β heat shock protein 70 Hsp70 HSV HSV-1 DNA polymerase HSV-1 TK human CDK2 human umbilical artery kinase regulation lipid signalling lipid-protein interaction lung cancer cell line membrane mitochondrial membrane potential MKK7 molecular biophysics molecular docking molecular docking simulation molecular dynamics multi-target drug multiple myeloma Mycobacterium tuberculosis NCI60 COMPARE analysis neuroprotection PGRMC1 phosphatidylinositols phytosterols piperine protein-ligand interaction reactive oxygen species (ROS) serum albumin serum half-life extension sigma ligands sigma receptors SIGMAR1 small-molecule derivatives of salicylanilide STD-NMR structure-activity relationship target identification thyroid diseases TMEM97 translocator protein (TSPO) UDP-galactopyranose mutase vascular homeostasis |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Protein—Ligand Interactions
Protein-Ligand Interactions Protein–Ligand Interactions |
| Record Nr. | UNINA-9910557497703321 |
Altieri Fabio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Women in Bioorganic Chemistry
| Women in Bioorganic Chemistry |
| Autore | Cardona Francesca |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (288 p.) |
| Soggetto topico |
Industrial chemistry and chemical engineering
Technology: general issues |
| Soggetto non controllato |
(p)ppGpp
1-deoxy-dxylulose 5-phosphate reductoisomerase (DXR) 2-C-methyl-derythritol 4-phosphate (MEP) pathway 3D molecular docking amelogenin amelogenin-derived peptides aminoproline scaffold AMR anti-cancer antibiotics anticancer activity antimicrobial antimicrobials antiproliferative activity benzamide betulinic acid biochemical studies BODIPY boron boron neutron capture therapy cancer cannabidiol chirality chiroptical cytotoxicity d-annulated steroids dental caries deoxyxylulose phosphate reductoisomerase dispirooxindoles enamel remineralisation enantiomers enzyme inhibition fluorescence probe fluorescent fosmidomycin fragment screening FT-IR spectroscopy glycosidase gold nanoparticles heterohelicene hydrazones hydroxyapatite iminosugars in vivo studies inhibition mechanism inhibitors insect trehalase integrin targeting interrupted Nazarov cyclization isoprenoid biosynthesis Jack bean α-mannosidase laser diffraction leucine-rich amelogenin peptides leukocyte integrins Lewis acid ligand design lipids liposomes mammalian trehalase molecular mechanisms multivalency n/a natural compounds neurological diseases neuroprotective effects p53/MDM2 interaction penetration enhancers pentacyclic steroids peptidomimetic synthesis persisters PET phthalimide postprandial hyperglycemia pyrene resolution screw-shaped compounds selectivity STD-NMR stratum corneum Strigol strigolactones sustainable agriculture synergistic effect terpenes thermal shift assay trehalose tyrosine-rich amelogenin peptides α-glucosidase α,α-difluorophosphonate β-galactosidase activity |
| ISBN | 3-0365-4990-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619464603321 |
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Cardona Francesca
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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