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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (528 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
ABT-737
acetazolamide acetylcholine adjuvant therapy amoeboid motility angiogenesis apoptosis arthralgia Bcl-2 family BCL2L10 biomarkers BRAF BRAF inhibitor BRAF inhibitors BRAF-mutant melanoma cancer cancer associated fibroblast cancer stem cells carbonic anhydrase cell therapy checkpoint inhibitor cholinergic system combined therapy ctDNA CXCL10 cyclopamine cytokines cytotoxicity diagnosis DOCK4 drug resistance essential oils exosomes extracellular vesicles FAK hedgehog HIPPO HuR immunity immunotherapy interferon invasion ipilimumab lactate dehydrogenase lipid metabolism liquid biopsy liver-directed-therapies machine learning MANS peptide MARCKS mechanism of action melanoma melanoma immune infiltrate melanoma markers melanoma metastasis melanoma PDX melanomagenesis metalloproteinases metastases metastasis metastatic dormancy metastatic therapy metastatic uveal melanoma (mUM) microenvironment microRNAs MITF ML258 motility mucosal melanoma muscarinic receptors n/a nanoparticles nicotinic receptors nivolumab OXPHOS patient stratification PD-1 pembrolizumab phosphorylation plasmacytoid dendritic cells prediction principal component analysis prognosis prognostication protein tyrosine phosphatase PTPs inhibitors Rac1 radiotherapy resistance rheumatoid arthritis sex-hormones sex/gender ShcD adaptor protein siRNA slow cycling phenotype small molecules SOCE STAT3 Support Vector Machine survival target therapy targeted therapy targeted-therapy therapeutic resistance therapy TLR TPC2 tumor microenvironment tumour microenvironment uveal melanoma (UM) WNT5A |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Catalyzed Synthesis of Natural Products
| Catalyzed Synthesis of Natural Products |
| Autore | Díez David |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (82 p.) |
| Soggetto topico | Chemistry |
| Soggetto non controllato |
?-amination
3-hydroxyoxindole acidolysis aminocatalysis antcin K anticancer Antrodia cinnamomea asymmetric catalysis asymmetric organocatalysis benzimidazole biotransformation carvone chiral ?-hydroxyamide deep eutectic solvents egg-yolk phosphatidylcholine epoxidation epoxide green chemistry immobilized lipases interesterification isatin mandelamides myristic acid n/a natural products organocatalysis phaeosphaeride A phaeosphaeride B proline Psychrobacillus STAT3 structural revision structured phosphatidylcholine total synthesis trimyristin triterpenoid zinc |
| ISBN | 3-03921-949-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367737103321 |
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Díez David
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Classification of Lymphomas and Hematological Neoplasia in the Era of Genomic Research : A Themed Issue in Honor of Dr. Elaine S. Jaffe
| Classification of Lymphomas and Hematological Neoplasia in the Era of Genomic Research : A Themed Issue in Honor of Dr. Elaine S. Jaffe |
| Autore | Nicolae Alina |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (252 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
lymphomas in PLWH
KSHV/HHV8 EBV lymphoma classification management cART HLX HOXB9 NFIB PBX1 STAT3 TLX2 autoimmune hemolytic anemia cold agglutinin B-cell lymphoproliferative disorder lymphomagenesis methylation histone modification indolent T-cell NK-cell lymphoproliferative disorder gastrointestinal tract genetics cell of origin T follicular helper cells TFH lymphoma angioimmunoblastic T-cell lymphoma follicular T-cell lymphoma peripheral T-cell lymphoma of T-follicular helper immunophenotype peripheral T-cell lymphoma primary cutaneous B-cell lymphoma primary cutaneous marginal zone B-cell lymphoma primary cutaneous follicle centre lymphoma primary cutaneous diffuse large B-cell lymphoma, leg-type primary cutaneous diffuse large B-cell lymphoma, not otherwise specified intravascular B-cell lymphoma EBV+ mucocutaneous ulcer Burkitt lymphoma epidemiology Plasmodium falciparum Epstein Barr virus registry studies multimodal cancer non-Hodgkin lymphoma HIV/AIDS follicular lymphoma in situ follicular neoplasia FL transformation FL in young patients diffuse large B-cell lymphoma NOS high grade B-cell lymphoma lymphoma gene expression profiling tumor microenvironment diagnostics centrocytic lymphoma intermediate lymphocytic lymphoma Jaffe mantle cell lymphoma mantle zone lymphoma cyclin D1 lymphomas people living with HIV tumor prevention in people living with HIV KSHV BCL2 rearrangement genetic alterations histological transformation targeted therapies transformed follicular lymphoma lymphoproliferative neoplasms of uncertain biological significance monoclonal B-cell lymphocytosis “in situ” follicular neoplasia “in situ” mantle cell neoplasia atypical germinal centers large B-cell lymphoma with IRF4 rearrangement “in situ” high-grade B lymphomas Hodgkin lymphoma |
| ISBN | 3-0365-5744-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Classification of Lymphomas and Hematological Neoplasia in the Era of Genomic Research |
| Record Nr. | UNINA-9910637783903321 |
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Nicolae Alina
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Curcumin in Health and Disease / Beatrice Bachmeier
| Curcumin in Health and Disease / Beatrice Bachmeier |
| Autore | Bachmeier Beatrice |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico | Chemistry |
| Soggetto non controllato |
minerals
cancer treatment chitosan neurodegeneration antioxidant activity senescence tumor proliferation nanoparticles antimicrobial agents oxidative metabolites drug discovery Akt/mTOR signaling micronutrients ulcerative colitis transmission electron microscopy metabolic reprogramming curcumin death receptor chaperone-mediated autophagy wound healing brain ischemia autophagy Alzheimer's disease genes transthyretin inflammatory bowel disease cellular pathway centrifugal partition chromatography nutrition amyloid Curcuma longa protein aggregation supportive care IL-17 senolytics complementary medicine macronutrients structure activity relationship gastroprotection Zingiberaceae anti-inflamation TLC bioautography microbiota glioblastoma multiforme amyloidosis SHMT2 antioxidants silica apoptosis reflux esophagitis gastric ulcer TLC-MS anti-cancer anticancer ImageJ anti-tumor delivery system wound Helicobacter pylori direct protein binding protein misfolding tumor growth diet Crohn's disease hydrostatic counter-current chromatography ageing renal cell cancer gastric cancer amino-acids STAT3 mechanism of action inflamm-aging mitophagy necrotizing enterocolitis cell cycling vitamins turmeric tuber cancer tau protein |
| ISBN |
9783039214501
3039214500 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367753703321 |
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Bachmeier Beatrice
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Delivery Technology Development in Canada
| Drug Delivery Technology Development in Canada |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (352 p.) |
| Disciplina | 615.1/900971 |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
3D spheroid
adenanthin amphotericin B antibodies bacteriophage bioaccessibility biodistribution biological barriers biologicals blood-brain barrier blood-brain barrier (BBB) Canada cancer canola oil deodorizer distillate cationic gemini surfactant child friendly formulation chronotherapy circadian clock cisplatin clinical trials co-delivery combination therapy controlled drug delivery developing world dissolution DOX-Vit D doxorubicin drug delivery drug delivery systems drug development drug discovery drug-resistant melanoma EGFR-targeted therapy emulsion encapsulation flavonoids formulation and dosage form development fungal infections gambogic acid gastrointestinal simulator GE11 peptide HAV6 cadherin peptide head and neck squamous cell carcinoma HIF-1 hypoxia-induced chemoresistance inclusion complex innovation intra-arterial chemotherapy lipid nanoparticles liposome liposomes loading gradients magnetic fields magnetic resonance imaging (MRI) malignant gliomas medical devices medulloblastoma mefloquine melphalan Metaplex MG63 model orange juice mouse models nanoparticles nifedipine oral oral delivery oral formulation parasitic infections permeation enhancers phage display pharmaceutics pharmacokinetics pharmacological Inhibitors of HIF-1 and STAT3 phospholipid complex photostabilizers phytosterols plant polymeric micelle precision medicine primary central nervous system lymphomas quercetin radiation radiolabeling remote loading ROESY NMR spectroscopy rosmarinic acid route of administration skin small molecules STAT3 staurosporine sustained delivery targeted therapies throughput TNO gastrointestinal model tocopherols topical formulation transdermal drug delivery transient modulation translational research triggered drug release ultrasound virus Vitamin D water miscible solvents |
| ISBN | 3-03928-005-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367736503321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Bioactive Natural Product Studies-A Southern Hemisphere Perspective
| Marine Bioactive Natural Product Studies-A Southern Hemisphere Perspective |
| Autore | Urban Sylvia |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (142 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
Alcyoniidae
anticancer activity antiplasmodial Aplidium apoptosis ascidian bioactive compounds bioactivity biosynthesis bisindole alkaloids brominated secondary metabolites cell death cembrane cephalostatin choline ester Cnemidocarpa stolonifera conotoxins crystal cytotoxicity diterpene docking Echinodermata ESI farnesyltransferase free energy perturbation HIF-1α holothurian HPCPC immunofluorescence assay indole ion channels Jurkat lobane malaria MALDI mandelalide marine invertebrate mass spectrometry methicillin resistant Staphylococcus aureus molecular dynamics MRSA PK natural product scaffold p42/p44 MAPK PC3 cell line PI3K/Akt/mTOR Plasmodium falciparum potential of mean force regioisomer salternamide A (SA) saponins sea cucumber ShK toxin Sinularia STAT3 structure elucidation synthesis taurine amide thiaplakortone thiaplidiaquinone thiazinoquinone tricyclic triterpene glycosides viscera X-ray |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557573903321 |
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Urban Sylvia
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (480 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
12-deacetyl-12-epi-scalaradial
3-alkylpyridinium polymers A375 and HeLa cell lines A549 cells ABC transporter actinomycin AD0157 adriamycin resistance Aeroplysinin Akt angiogenesis angiogenesis inhibitor ansamycins anthranilic acid anti-angiogenesis anti-angiogenic anti-cancer anti-metastatic activity anti-proliferation anti-proliferative antiangiogenesis antiangiogenic antibacterial Antibody Drug Conjugates (ADCs) anticancer anticancer activity anticancer agent anticancer immunity anticarcinogenic anticoagulant anticoagulation antifouling Antimicrobial peptide (AMP) antioxidant antiproliferative antiproliferative activity antitumor antitumor activities antitumoral antitumour AP-1 apoptosis apoptosis-inducing activity approved antitumor agents araguspongine C arrest of cell cycle Aspergillus autophagy autophagy inducers autophagy inhibitors azoxymethane BCRP/ABCG2 BEL-7402 cell benzo[a]pyrene bioactive natural product bioanalysis bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) bonnethead shark breast cancer breast cancer cells Brevianamide brominated indoles bromophenol buccal gland c-JUN c-Met C15 acetogenins camptothecin cancer Cancer cancer genes cancer preventive cancer progression Cantabrian Sea-derived actinobacteria carbocyclic analogue carcinoembryonic antigen Caribbean sponge carotenoid carotenoids caspase cascade cell adhesion cell adhesion molecules cell cycle cell cycle arrest cell migration cembranoids chemical conjugation chemoprevention chemopreventive chemosensitization chemotherapy chimera CHOP chromatography circulating tumor cells cisplatin clinical trials colorectal cancer cooperative binding cyclin D1 cyclin-dependent kinase CYP1A1 cystatin F cystatin superfamily cytokine release cytoskeleton cytotoxic activity cytotoxicity deep-sea depolymerisation dibromotyrosine dieckol divergolides DNA minor groove binder drug discovery Ecklonia cava elisidepsin EMT endoperoxide endophytic fungus endothelial cells energy stress epigonal organ epithelial-mesenchymal transition ER-stress ET-743 evolution FAK fascaplysin fatty acid 2-hydroxylase fatty acids FAU FBDD fucoidan fucoxanthin fumigaclavine C gemcitabine gene expression glioblastoma gliotoxin glucocorticoid receptor glycosaminoglycans gorgonian Haliclona gracilis HeLa cells heparan sulphate heparanase hepatocellular carcinoma HER2 HIF-1 hippuristanol HSP90 human lung cancer human normal diploid fibroblast (TIG-1 cells) human sarcoma cell line (HT1080 cells) humulane sesquiterpenoids hybridization hydroxylated lipids hypoxia hypoxia-inducible factor-1 IL-6 in vivo model inflammation inhibitor integrin β1 invasion isatin Isofistularin itampolin A jaspine B JNK1/2 Jurkat kalkitoxin kunitz type inhibitor Lampetra morii Leathesia nana Leptogorgia leukemia lipid rafts low molecular weight fucoidan extract low toxic LS-1 lung cancer lung metastasis Lyngbya majuscula macrolide mangrove-derived actinomycete manzamine A MAPK/ERK pathway marangucyclines marine antitumor agents marine biotechnology marine compound marine drug marine drugs marine fungus marine metabolites marine mollusc marine natural products marine organisms marine sponges marine-derived drugs Marthasterias glacialis L. MCP-1 mechanisms of action melanoma membrane permeabilization metastasis microalgae Micromonospora migration mitochondria mitochondria toxin mitochondrial pathway mitochondrial dysfunction molecular docking molecular mechanisms molecular modeling molecular oncology Moorea producens MRP1/ABCC1 multi-drug resistant leukemia multidrug resistance Mycalin A Mycochromenic acid derivative N-Ras n/a nanoparticle naphthopyrones natural marine compounds natural product natural products neuroblastoma-rat sarcoma NF-κB NF-κB signaling nicotine nicotinic acetylcholine receptor non-small cell lung cancer non-small cell lung cancer (NSCLC) non-small cell lung carcinoma nonfunctioning pituitary adenomas novel inhibitor NSCLC Nur77 osteosarcoma oxidative stress oxidative stress P-gp/ABCB1 P2X7 receptor p38 p38/ERK p38α p65 pachastrissamine palmitic acid paulomycins pazopanib PEL Penicillium brevicompactum Penicillium paneum phase I pheochromocytoma and paraganglioma phlorotannins phycocyanin PI3K/Akt plakortide plitidepsin pollution poly(ADP-ribose)-polymerase inhibitor polyoxygenated steroids polyphenols polysaccharides Porifera porifera/sponge preclinical programmed cell death programmed cell death-ligand 1 programmed cell death-ligand 2 proliferation prostate cancer proteasomal degradation proteomic pseudopterosin puupehenones pyrrolidinedione reactive oxygen species RGD motif ribosomal protein genes ROS RPS30 safety Sarcophyton ehrenbergi sea anemone sea cucumbers seaweed secondary metabolites sediment selenium-containing polysaccharide-protein complex Sepia ink polysaccharides shrimp signal transduction sinulariolide sipholenol A small cell lung cancer SNORA62 snoRNA SNU-C5/5-FU soft coral soft tissue sarcoma soft tissue sarcoma sphingosine kinase inhibitor sponge sponges STAT3 Streptomyces sp. SCSIO 11594 synergism synthetic analogues SZ-685C targeted therapy terpenes tetracenomycin X TGF-β signaling Thalassia testudinum thalassiolin B therapeutic compounds Tilapia piscidin 4 (TP4) TNFα Topo I inhibitor topoisomerase trabectedin triterpene glycosides TRPM7 tumor cell line tumor microenvironment tumor-associated macrophages Ulva fasciata uveal melanoma VEGF virtual screening xyloketal B α9-nicotinic acetylcholine receptors (nAChRs) αO-conotoxin GeXIVA β1-integrin λ-carrageenan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Natural Products as Anticancer Agents
| Marine Natural Products as Anticancer Agents |
| Autore | Alves Celso |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (150 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
alga
anti-cancer antitumor aplysinopsin analogs apoptosis astaxanthin BH3 mimetics bioactive compounds biscembranoid-type metabolites BT20 cancer stem cells cancer therapy chronic myeloid leukemia colony formation cytotoxicity Ehlich's tumor environment epigenetic signaling epigenome epithelial-mesenchymal transition flaccidoxide-13-acetate gram-scale hepatocellular carcinoma hydroxyphenylacetic acid indole alkaloids inflammation inflammatory factor production invasion LPS-stimulated murine macrophage marine source marine species marine-derived fungus meroterpenoids migration mutp53 n/a nannocystin Nanog natural product Oct4 P. purpurogenum Penicillium chrysogenum polyketide pontin proliferation prostate cancer Sarcophyton digitatum secondary metabolites siRNA STAT3 T47D total synthesis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557595603321 |
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Alves Celso
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases
| Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases |
| Autore | Kwok Hang Fai |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (180 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
AKT
amphibian Bowman-Birk inhibitor amyloidogenesis anionic lipids anti-inflammation anticancer therapy anticancer therapy/cancer treatment antifungal antioxidant apoptosis Asteraceae Astragalus membranaceus Bcl-2 family proteins binding affinity branched-chain fatty acids cell cycle arrest colorectal cancer Conidiobolus heterosporus COX-2 DAPK1 docetaxel drug delivery system drug design endoplasmic reticulum F23R variant fatty acid oxidation fibroblasts fucoidan G-protein activation gingiva hepatocyte hIAPP iNOS insulin insulin granules kynurenines lignan lipid metabolism lung cancer molecular cloning molecular docking n/a natural-based compound NO orientin PDX-1 peptides peroxisome proliferator-activated receptor α Petasites japonicus PGE2 pharmacophore PI3K PLGA pomegranate post-translational modification PPARγ protease inhibitor protein degradation punicalagin SENP STAT3 SUMO survivin tannins Tat peptide unfolded protein response wound healing β-cell cytotoxicity β-sheet transitions μ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607403321 |
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Kwok Hang Fai
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases
| Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases |
| Autore | Rustum Youcef M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (166 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
anticancer
anticancer agent antitumor activity apoptosis cancer cancer stem cells cell plasticity chemotherapeutics clear cell renal cell carcinoma clear-cell renal cell carcinoma microRNAs disease DNA damage DNA damage and repair EMT entosis epigenetics ER stress glutathione head and neck cancer HIF hSP56 hypoxia hypoxia-inducible factor hypoxia-inducible factors (HIFs) immune evasion isoselenourea lipid peroxidation malignant melanoma methylseleninic acid methylselenocysteine methylselenoesters miRNA mTOR inhibitors PD-L1 radiation SBP1 Se-containing nanoparticles SELENBP1 selenium selenium species selenium-binding protein 1 seleno-l-methionine STAT3 tocopherol tumor heterogeneity tumor microenvironment VEGF viability |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346851003321 |
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Rustum Youcef M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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