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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (528 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
ABT-737
acetazolamide acetylcholine adjuvant therapy amoeboid motility angiogenesis apoptosis arthralgia Bcl-2 family BCL2L10 biomarkers BRAF BRAF inhibitor BRAF inhibitors BRAF-mutant melanoma cancer cancer associated fibroblast cancer stem cells carbonic anhydrase cell therapy checkpoint inhibitor cholinergic system combined therapy ctDNA CXCL10 cyclopamine cytokines cytotoxicity diagnosis DOCK4 drug resistance essential oils exosomes extracellular vesicles FAK hedgehog HIPPO HuR immunity immunotherapy interferon invasion ipilimumab lactate dehydrogenase lipid metabolism liquid biopsy liver-directed-therapies machine learning MANS peptide MARCKS mechanism of action melanoma melanoma immune infiltrate melanoma markers melanoma metastasis melanoma PDX melanomagenesis metalloproteinases metastases metastasis metastatic dormancy metastatic therapy metastatic uveal melanoma (mUM) microenvironment microRNAs MITF ML258 motility mucosal melanoma muscarinic receptors n/a nanoparticles nicotinic receptors nivolumab OXPHOS patient stratification PD-1 pembrolizumab phosphorylation plasmacytoid dendritic cells prediction principal component analysis prognosis prognostication protein tyrosine phosphatase PTPs inhibitors Rac1 radiotherapy resistance rheumatoid arthritis sex-hormones sex/gender ShcD adaptor protein siRNA slow cycling phenotype small molecules SOCE STAT3 Support Vector Machine survival target therapy targeted therapy targeted-therapy therapeutic resistance therapy TLR TPC2 tumor microenvironment tumour microenvironment uveal melanoma (UM) WNT5A |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Islet Inflammation and Metabolic Homeostasis
| Islet Inflammation and Metabolic Homeostasis |
| Autore | Collier Jason |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (126 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
beta cell death
beta cell dysfunction beta cell failure beta cell hyperfunction beta cell hypofunction beta-cell function cytokine diabetes ER stress glucolipotoxicity gut microbiome hyperglycemia inflammation insulin insulin resistance insulin secretion insulin sensitivity islet islet of Langerhans ketogenic diet low carbohydrate diet macrophage n/a NADPH oxidases obesity oxidative stress pancreas pancreatic beta cell polyunsaturated fatty acids proinflammatory cytokines prostaglandins Rac1 saturated fatty acids transcriptomics type 2 diabetes untargeted plasma metabolomics β-cell |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557767303321 |
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Collier Jason
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot
| Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot |
| Autore | Jongbloed Monique |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (372 p.) |
| Soggetto topico | Public health and preventive medicine |
| Soggetto non controllato |
acute aortic syndrome
anomalous left subclavian artery aorta aortic regurgitation aortic stenosis aortic surgery aortic valve replacement aortic wall arrhythmogenic right ventricular dysplasia arteria lusoria arterial duct arterial switch operation asymptomatic atrioventricular valve Bentall bicuspid aortic valve candidate genes cardiac development cardiac fields cardiac progenitor cells cardiomyocyte cardiovascular development cardiovascular disease cardiovascular pathogenesis cartilage cell identity cell polarity cleft palate compact myocardium congenital heart defects congenital heart disease coronary arteries coronary artery coronary artery anatomy coronary complications cushion developmental biology discordant phenotype dissection of ductus arteriosus DNA methylation ductus arteriosus early surgery endocardial cushions endocardial fibro-elastosis endocardium epicardium epigenetics esophageal compression fetal aortic stenosis foramen of Panizza free edge folding genetics heart tube homograft imaging Kommerell's diverticulum lateral cushion left aorta Leiden Convention coronary coding system lineage tracing Lipton classification loeys dietz syndrome-5 major cushion monozygotic twins myofibroblasts myxomatous degeneration neointima neural crest neural crest cell original leaflet outflow tract outflow tract septation pharyngeal arch arteries pharyngeal arch artery pharyngeal ectoderm postmortem histology prenatal ultrasound progenitor specification proliferation pulmonary trunk Rac1 remodeling rienhoff syndrome right aorta right sided aortic arch second heart field semilunar valves signaling networks single coronary artery speckle tracking analysis sudden unexpected intrauterine death superimposed tissue surgical Tetralogy of Fallot trabeculation tracheal compression transcription factor AP-2α transcriptome transforming growth factor beta-3 transposition great arteries coronary anatomy transposition of the great arteries tunica media valve variations watchful waiting |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Leaders in Cardiovascular Research |
| Record Nr. | UNINA-9910585946203321 |
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Jongbloed Monique
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Pathways in Cancers
| Molecular Pathways in Cancers |
| Autore | Cristóbal Ion |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (284 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
acetylation
actin cytoskeletal reorganization adaptive immunity advanced ovarian cancer anti-receptor therapy BET inhibitors biomarkers bladder cancer initiation breast cancer CALR cancer cancer immunology cancer therapeutics carcinogenicity CD99 agonist complement system DUSP1 EGFR dimerization endocytosis epigenetic epigenome epithelial cells FAK dephosphorylation genome glioblastoma gp120 hepatocellular carcinoma human immunodeficiency virus type 1 immune checkpoint inhibitors immune evasion immunotherapy innate immunity JAK2 luminal breast cancer MAPK matrix protein p17 metastasis metastatic melanoma methylation migration and invasion mitochondria molecular targeted agents MPL MS-determined phosphopeptides mTOR myeloproliferative neoplasms n/a Nef NIMA-related kinase 1 (NEK1) non-coding RNA OMD oncogenic signaling pathway ovarian cancer oxidative stress OXPHOS pancreatic ductal adenocarcinoma partial EMT patient survival pBRD4 PI3K PP2A PRELP prognosis prostate cancer PTPN12 Rac1 reactive oxygen species resistance reverse transcriptase RhoA SET signaling pathways small-cell lung cancer Snail splicing pathway TAK-228 Tat thioridazine (THD) tight junction tousled-like kinase (TLK) TPOR trastuzumab tripeptide triple negative breast cancer triple-negative breast cancer tumor immune microenvironment tumor microenvironment tumor suppression gene Warburg effect yes-associated protein 1 (YAP1) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566473703321 |
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Cristóbal Ion
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sodium Intake and Related Diseases
| Sodium Intake and Related Diseases |
| Autore | Strazzullo Pasquale |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (90 p.) |
| Soggetto topico |
Biology, life sciences
Food & society Research & information: general |
| Soggetto non controllato |
ambulatory heart failure
blood pressure cardiovascular risk ENaC epidemiological studies heart failure high potassium hypertension inflammation leaky epithelia mineralocorticoid receptor mortality MST3 n/a Na+ cotransport NKCC2 OSR1 prognosis Rac1 renal injury salt salt intake salt-sensitive hypertension sodium SPAK STK24 tight junction WNK4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566468003321 |
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Strazzullo Pasquale
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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