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Genomics and Models of Nerve Sheath Tumors
| Genomics and Models of Nerve Sheath Tumors |
| Autore | Hirbe Angela C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (172 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
neurofibromatosis type 1
nerve sheath tumor cancer latent variables machine learning supervised learning transfer learning random forest metaVIPER tumor deconvolution neurofibromatosis malignant peripheral nerve sheath tumor MPNST polycomb repressive complex PRC2 NF1 kinase kinome adaptation kinome reprogramming MET MEK doxorubicin capmatinib tram genomics tumor evolution pathology next generation sequencing clinical genetics malignant peripheral nerve sheath tumors plexiform neurofibromas Schwann cells neurofibromatosis type 1 syndrome neurofibromin 1 genetically engineered mouse models heterogeneity CRISPR/Cas9 mouse models sarcoma tumor microenvironment neurofibromatosis 1 (NF1) mebendazole (MBZ) COX-2 inhibitor malignancy chemoprevention nerve sheath tumors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557484703321 |
Hirbe Angela C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Seed Dormancy : Molecular Control of Its Induction and Alleviation
| Seed Dormancy : Molecular Control of Its Induction and Alleviation |
| Autore | Matilla Angel J |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (124 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
chestnut
GABA seed germination carbon metabolism nitrogen metabolism DOG1 seed dormancy ABA ethylene clade-A PP2C phosphatase (AHG1 AHG3) after-ripening asDOG1 heme-group association mapping climate adaptation germination genomics legumes Medicago plasticity physical dormancy DNA methylation oxidation RNA stability seed vigour ROS primary dormancy ABI3 auxin YUC PIN ARF endosperm integuments AGL62 PRC2 RNA-Seq dormancy termination gene expression antioxidants ethylene signaling environmental signals long-lived mRNA monosomes auxin and ABA alternating temperatures |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Seed Dormancy |
| Record Nr. | UNINA-9910557296703321 |
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Matilla Angel J
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Towards Mechanism-based Treatments for Fragile X Syndrome
| Towards Mechanism-based Treatments for Fragile X Syndrome |
| Autore | Kumari Daman |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (250 p.) |
| Soggetto non controllato |
lymphoblast
pluripotent stem cells FMR1 Gene editing X chromosome Fmr1 epigenetic gene silencing FMR1 gene Fragile X syndrome 1 repeat instability characteristics that have the greatest impact DNA instability working memory language development mosaicism CRISPR 3 clinical trials autism spectrum disorders Fmr1 KO mouse automated vocal analysis base excision repair (BER) inhibitory control cerebral spinal fluid iPSC drug development targeted treatments molecular biomarkers viral vector avoidance biomarker set-shifting early identification expansion anxiety planning voice of the person mismatch repair (MMR) gene reactivation double-strand break repair (DSBR) newborn screening intellectual disability processing speed voice of the patient fragile X syndrome adeno-associated virus neurodevelopmental disorders histone methylation Non-homologous end-joining (NHEJ) ASD Fxr2 Fragile X-associated Tremor/Ataxia Syndrome 2 Trinucleotide Repeat 4 CGG Repeat Expansion Disease DNA methylation contraction fragile X mental retardation protein RNA:DNA hybrid behavior developmental disorders cognition females FMRP Fragile X Syndrome unstable repeat diseases protein synthesis brain cognitive flexibility treatment development fibroblast PRC2 transcription coupled repair (TCR) best practices attention Fragile X executive function |
| ISBN | 3-03921-506-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367759103321 |
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Kumari Daman
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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