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Molecular Psychiatry
| Molecular Psychiatry |
| Autore | Rein Theo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Mental health services |
| Soggetto non controllato |
cardiovascular disease
cell adhesion molecules immunology inflammation nervous system schizophrenia bipolar disorder major depressive disorder DNA methylation response variability antipsychotics drug design multi-target drugs polypharmacology multi-task learning machine learning biomarker discovery psychiatry serotonin 5-HT 4 receptor 5-HT4R depression mood disorder expression Alzheimer's disease cognition Parkinson's disease forced swimming Roman rat lines stress hippocampus BDNF trkB PSA-NCAM western blot immunohistochemistry general cognitive function intelligence GWAS genetic correlation childhood-onset schizophrenia (COS) induced pluripotent stem cell (iPSC) copy number variation (CNV) early neurodevelopment neuronal differentiation synapse dendritic arborization miRNAs stress physiology cytoskeleton actin dynamics DRR1 TU3A FAM107A acid sphingomyelinase alcohol dependence liver enzymes sphingolipid metabolism withdrawal Hsp90 GR stress response steroid hormones molecular chaperones psychiatric disease circadian rhythms FKBP51 FKBP52 CyP40 PP5 DISC1 neurodevelopment CRMP-2 proteomics antidepressant treatment HPA axis gene expression FKBP5 sleep sleep EEG biomarkers antidepressants cordance gender sex difference antidepressant rapid-acting Ketamine endocrinology (2R,6R)-Hydroxynorketamine electroconvulsive therapy basic-helix-loop-helix brain coactivator glucocorticoids mineralocorticoid receptor knockout transcription biology dopaminergic gene polymorphisms affective temperament obesity alpha-synuclein SNCA major depression Hamilton Scale of Depression chemokines neuroinflammation social defeat Immune response T cells susceptibility resilience Treg cells Th17 cells behavior PPARγ |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557793503321 |
Rein Theo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases
| Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases |
| Autore | Kwok Hang Fai |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (180 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
DAPK1
SUMO SENP protein degradation post-translational modification amphibian Bowman-Birk inhibitor Tat peptide molecular cloning antifungal drug design protease inhibitor natural-based compound anticancer therapy lung cancer survivin apoptosis STAT3 colorectal cancer orientin cell cycle arrest Bcl-2 family proteins Astragalus membranaceus insulin PI3K AKT PPARγ PDX-1 Petasites japonicus Asteraceae lignan anti-inflammation NO PGE2 iNOS COX-2 molecular docking peptides kynurenines binding affinity μ-opioid receptor pharmacophore G-protein activation fucoidan PLGA docetaxel drug delivery system anticancer therapy/cancer treatment hIAPP amyloidogenesis insulin granules endoplasmic reticulum anionic lipids F23R variant β-sheet transitions β-cell cytotoxicity unfolded protein response pomegranate punicalagin tannins gingiva fibroblasts antioxidant wound healing branched-chain fatty acids Conidiobolus heterosporus peroxisome proliferator-activated receptor α lipid metabolism fatty acid oxidation hepatocyte |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607403321 |
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Kwok Hang Fai
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutraceuticals and Human Health
| Nutraceuticals and Human Health |
| Autore | Scotto D'Abusco Anna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (340 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
fertility
ingredients male reproduction semen parameters supplements allithiamine garlic hyperglycaemia advanced glycation end-products cytokines abscisic acid prediabetes type 2 diabetes mellitus metabolic syndrome insulin resistance adipocyte browning AMP-activated protein kinase food supplement frambinone meal frequency open-field test elevated plus maze sensory motor gating pre-pulse inhibition c-Fos amyotrophic lateral sclerosis anti-inflammatory antioxidant phenolic acid neuroprotective neurodegeneration obesity overweight beta-glucans chitosan follow up study weight loss programs weight gain weight loss body weight changes phytoplankton antioxidants muscle damage muscle recovery muscle soreness Viburnum opulus phenolic compounds adipogenesis PPARγ lipase inhibition green tea epigallocatechin lipid profile high-fat diet fast food osteoarthritis nutraceuticals polyphenols volatile compounds β-caryophyllene eugenol FAAH cannabinoid receptors phospholipases lactoferrin bovine milk nutraceutical human health resveratrol curcumin cisplatin head and neck cancer cell cycle apoptosis prostate cancer microbiota nutraceutical compounds fecundation inflammation cytokine growth factors metabolomics lipidomics ω-3PUFAs ω-6PUFAs endocannabinoids CRC fatty acids Gymnema inodorum gymnemic acid Mikania micrantha anti-hypercholesterolemia steatosis olive leaf macrophages |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557408003321 |
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Scotto D'Abusco Anna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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PPARs as Key Mediators of Metabolic and Inflammatory Regulation
| PPARs as Key Mediators of Metabolic and Inflammatory Regulation |
| Autore | Vázquez-Carrera Manuel |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (456 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
nuclear receptor
gene transcription inflammation molecular docking PPARβ/δ lung pulmonary artery GW0742 GSK3787 docking lipopolysaccharide (LPS) PPARγ ligand coumarin fluorescent ligand screening crystal structure PPAR atopic dermatitis psoriasis metabolic reprograming glucose fatty acids mycobacteria M. tuberculosis M. leprae PPARs lipid droplets metabolic alterations hepatic damage nuclear factors pharmacological targets AMPK GDF15 insulin resistance type 2 diabetes mellitus peroxisome proliferator-activated receptor gamma (PPARγ) real-time PCR ELISA immunohistochemistry signaling pathway PPAR gamma brain neural stem cells infection neuroinflammation HIV Zika cytomegalovirus neurogenesis microglia liver damage toll-like receptor 4 P2Y2 receptor metabolic syndrome resveratrol quercetin PPARα peroxisome β-oxidation PPRE ligand coregulator micronutrients PPARα knockout adipose tissue browning lipid metabolism depression PPARg neuropathology corticotropin releasing hormone norepinephrine subgenual prefrontal cortex amygdala nucleus accumbens common carotid artery occlusion electroretinography fibroblast growth factor 21 pemafibrate peroxisome proliferator-activated receptor alpha retinal ischemia skeletal muscle substrate metabolism nonalcoholic fatty liver disease (NAFLD) sex dimorphism lipidomics hepatic sex-biased gene expression PPARγ pulmonary arterial hypertension TGFβ vascular injury proliferation kidney fibrosis pattern-recognition receptors phagocytosis nitric oxide synthase fenofibrate oleoylethanolamide palmitoylethanolamide cancer immunity obesity diabetes miRNA DNA methylation histone modification peroxisome-proliferator-activated receptor fatty acid oxidation doping control regulatory T cells exercise nuclear receptors nutrigenomics energy homeostasis dairy animals non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) peroxisome proliferator-activated receptors (PPAR) bezafibrate fenofibric acid peroxisome proliferator-activated receptor dual/pan agonist X-ray crystallography |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576873703321 |
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Vázquez-Carrera Manuel
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Health Benefits of the Bioactive Compounds in Foods
| The Health Benefits of the Bioactive Compounds in Foods |
| Autore | Jaime Laura |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
phytochemicals
antioxidant antinausea antiobesity anticancer anti-inflammatory ‘Cara Cara’ juice storage hydrophilic and lipophilic antioxidant carotenoid flavonoid degradation dried distilled spent grain (DDSG) melanoidins content structure antioxidant activity ACE-inhibitory activity beverages brewing method antioxidant potential total polyphenols content mineral composition grape stem phenolic compounds central composite rotatable design sustainable food systems pressurized liquid extraction side streams valorisation curcumin milk proteins nanoparticles antimicrobial activities bioactive peptides hypertension functional food metabolic syndrome microbiota insulin sensitivity polyphenols grape pomace donkey milk (DM) donkey colostrum (DC) mammal’s milk cow’s milk protein allergy (CMPA) biologic activity immunosenescence health benefits cryoconcentration calafate juice storage time physicochemical properties bioactive compounds sensorial analysis apitherapy royal jelly propolis bee pollen sarcopenia dietary interventions muscle skeletal muscle wasting physical performance coronavirus disease 2019 COVID-19 body composition lean body mass insulin resistance mitochondrial dysfunction satellite stem cells polysaccharide purification anti-obesity proliferation PPARγ biological activities isolation analysis mechanism of action bioaccessibility intestinal absorption bioavailability |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557361603321 |
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Jaime Laura
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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