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Albumin-Based Drug Delivery Systems
| Albumin-Based Drug Delivery Systems |
| Pubbl/distr/stampa | Basel : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2022 |
| Descrizione fisica | 1 electronic resource (162 pages) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
plasma half-life extension
albumin conjugation in vivo glucose-lowering activity glucagon-like peptide-1 quality by design rapid equilibrium dialysis muco-adhesion brain PAMPA RPMI 2650 nasal epithelial cell human serum albumin dimerization doxorubicin enhanced permeability and retention effect antitumor Arthrobacter globiformis gout half-life extension inverse electron demand Diels-Alder reaction site-specific albumin conjugation thermostability urate oxidase albumin anti-thrombotic CD39 coating of medical devices stent coating therapeutic fusion protein conjugates vanadium cancer prodrug hydrogels EPR/ESR spectroscopy release behavior disulfide glioma conjugate albumin binding moieties peptides Evans blue 4-(p-iodophenyl)butyric acid integrin αvβ6 integrin αvβ6 binding peptide improved pharmacokinetics PET imaging |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576888003321 |
| Basel : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Deep Learning in Medical Image Analysis
| Deep Learning in Medical Image Analysis |
| Autore | Zhang Yudong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (458 p.) |
| Soggetto non controllato |
interpretable/explainable machine learning
image classification image processing machine learning models white box black box cancer prediction deep learning multimodal learning convolutional neural networks autism fMRI texture analysis melanoma glcm matrix machine learning classifiers explainability explainable AI XAI medical imaging diagnosis ARMD change detection unsupervised learning microwave breast imaging image reconstruction tumor detection digital pathology whole slide image processing multiple instance learning deep learning classification HER2 medical images transfer learning optimizers neo-adjuvant treatment tumour cellularity cancer breast cancer diagnostics imaging computation artificial intelligence 3D segmentation active surface discriminant analysis PET imaging medical image analysis brain tumor cervical cancer colon cancer lung cancer computer vision musculoskeletal images lung disease detection taxonomy convolutional neural network CycleGAN data augmentation dermoscopic images domain transfer macroscopic images skin lesion segmentation infection detection COVID-19 X-ray images bayesian inference shifted-scaled dirichlet distribution MCMC gibbs sampling object detection surgical tools open surgery egocentric camera computers in medicine segmentation MRI ECG signal detection portable monitoring devices 1D-convolutional neural network medical image segmentation domain adaptation meta-learning U-Net computed tomography (CT) magnetic resonance imaging (MRI) low-dose sparse-angle quantitative comparison |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557435103321 |
Zhang Yudong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular, Cellular and Model Organism Approaches for Understanding the Basis of Neurological Disease
| Molecular, Cellular and Model Organism Approaches for Understanding the Basis of Neurological Disease |
| Autore | Robert J. Harvey |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (183 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Stem Cells
glycine receptor Amyotrophic Lateral Sclerosis Parkinson's disease PET imaging LRRK2 Zebrafish Inflammation GABA-A receptor NMDA receptors Intellectual Disability |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910220035303321 |
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Robert J. Harvey
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Radiolabelled Molecules for Brain Imaging with PET and SPECT
| Radiolabelled Molecules for Brain Imaging with PET and SPECT |
| Autore | Brust Peter |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (244 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
SV2A
SV2B SV2C microPET [18F]UCB-H epilepsy PBIF distribution volume blocking assay preclinical imaging Alzheimer’s disease (AD) network measure graph theory brain network positron emission tomography (PET) persistent homology Phosphodiesterase 2A (PDE2A) Positron Emission Tomography (PET) Benzoimidazotriazine (BIT) fluorinated Mouse Liver Microsomes (MLM) cyclic nucleotide phosphodiesterase PDE2A radioligand nitro-precursor fluorine-18 in vitro autoradiography PET imaging opioid receptors positron emission tomography radiotracers μOR-, δOR-, κOR- and ORL1-ligands movement disorders pain drug dependence GBM biomarkers Sigma 1 Sigma 2 PD-L1 PARP IDH Alzheimer’s disease Parkinson’s disease β-amyloid plaques neurofibrillary tangles α-synucleinopathy diagnostic imaging probes orexin receptors PET radiotracer imaging alpha 7 nicotinic acetylcholine receptors nAChR autoradiography amino acid FET FACBC FDOPA immunoPET molecular imaging glioma brain metastases adenosine A2A receptor rotenone-based mouse model [18F]FESCH two-step one-pot radiosynthesis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557295103321 |
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Brust Peter
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Radiopharmaceuticals for PET Imaging - Issue A
| Radiopharmaceuticals for PET Imaging - Issue A |
| Autore | Roivainen Anne |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (212 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
kinetic analysis
Siglec-9 gallium-68 vascular adhesion protein VAP-1 infection inflammation osteomyelitis animal model Staphylococcus aureus multiple myeloma positron emission tomography/computed tomography radiopharmaceuticals 18F-fluorodeoxyglucose tetrazine ligation PET SPECT indium-11 fluorine-18 positron emission tomography (PET), defluorination isotopic exchange silicon-based fluoride acceptor bioorthogonal chemistry tetrazine inverse electron-demand Diels-Alder ligation opioid naloxone overdose fentanyl carfentanil [11C]carfentanil positron emission tomography receptor occupancy pharmacokinetics [18F]AlF NOTA NODAGA PODS thiol-reactive linker affibody molecule bioconjugation EGFR tumor imaging vulnerable plaque molecular imaging PET imaging nanobody single-domain antibody sub-millimetre resolution AlF-radiolabelling preclinical radiopharmaceutical dosimetry image-based internal dosimetry OLINDA MCT1/MCT4 lactate transporter inhibitor [18F]FACH radiation safety sigma-1 receptor availability orthotopic xenograft of glioblastoma in mouse small animal Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) (S)-(−)-[18F]fluspidine imaging-based biomarker SV2A protein PET radiotracers synaptic loss radiochemistry preclinical development clinical outcomes monocarboxylate transporters (MCTs) FACH 18F-labeled analog of FACH α-CCA blood-brain barrier (BBB) positron emission tomography (PET) imaging peptides proteolysis metabolic stability |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557437003321 |
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Roivainen Anne
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications
| Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications |
| Autore | Doti Nunzianna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
polymers
peptidomimetics AFM transfection molecular modelling peptide α-helix hydrocarbon stapling ring-closing metathesis i,i + 1 staple X-ray structure deferoxamine RGD peptides integrins radiodiagnostics PET imaging retro-inverso peptides anticancer peptides drug delivery peptide antigens Aβ IAPP antimicrobial peptides peptides diagnostic ELISA microarray PET SPECT imaging diagnostic non-imaging diagnostic amphiphilic peptides non-viral gene delivery nanocarrier peptide self-assemblies stimuli responsive SARS-CoV-2 FRET molecular docking molecular dynamics MM-GBSA drug repurposing antiviral cancer cyclic peptide integrin αvβ3 ALOS4 melanoma fluorescent peptide environment-sensitive fluorophore peptide labeling luciferin membrane-binding peptide antimicrobial peptide antitumor peptide RGD peptide antiproliferative activity chirality conformational analysis density functional theory (DFT) ferrocene hydrogen bonds peptidomimetic X-ray protein–protein interactions (PPIs) voltage-gated Na+ (Nav) channels fibroblast growth factor 14 (FGF14) medium spiny neurons (MSNs) nucleus accumbens (NAc) neurotherapeutics cyclophilin A (CypA) apoptosis-inducing factor (AIF) human neuroblastoma SH-SY5Y cells staurosporine-mediated cell death AIF(370-394) peptide caspase-3 PARP antifungal antibacterial peptide-based therapies synthetic peptides |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Synthetic Peptides and Peptidomimetics |
| Record Nr. | UNINA-9910580210803321 |
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Doti Nunzianna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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