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Antiviral Agents
| Antiviral Agents |
| Autore | Adamson Catherine |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (386 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
acteoside
acute/latent infection acyclovir adoptive cell therapy antipsychotic drug antiviral antiviral activity antiviral agent antiviral agents antiviral drug antiviral effect antiviral inhibitor antiviral strategies branched peptides brevilin A Burkitt lymphoma cells C-FRA cathelicidins central nervous system chemical footprinting Clerodendrum trichotomum clozapine combination antiretroviral therapy (cART) congenital infection coxsackievirus B4 CRISPR/Cas cytomegalovirus defensins dried blood spots dried plasma spots drug discovery endocytosis enteroviruses epigallocatechin gallate Epstein-Barr virus Ethiopia flavivirus flavonoids fluoxetine furin inhibitor ganciclovir genistein ginsenoside Rg1 glycosphingolipids HCMV vaccine hemagglutinin (HA) heparan sulfate hepatitis C virus hepcidins herpes B virus herpes viruses herpesvirus HIV human antimicrobial peptides human immunodeficiency virus ie-1 gene IE1 IE2 immediate-early influenza A virus influenza A virus (IAV) Japanese encephalitis virus latent infection lectin lipid biosynthesis LUMS1 lytic gene expression macacine herpesvirus-1 measles virus microvirin mutations n/a neural stem cells NF-κB signaling pathway non-immunogenic NS5 nucleic acid-based therapeutic approach nucleoside analogues oleanane-type derivatives orthohantavirus pediatrics PEI persistent infection phenyl-benzotriazoles Plantago asiatica polyethylenimine Porcine circovirus type 2 porcine reproductive and respiratory syndrome virus pre-treatment drug resistance precursor membrane protein pro-inflammatory factor prodrugs protein drugs ProTides PRRSV quantitative real-time PCR replication resistance Rev response element ribozyme RNA interference RNA-dependent RNA polymerase RSV sesquiterpene lactone SHAPE small molecule sphingolipids Surveyor nuclease mutation detection assay TALEN therapeutic effects therapeutic strategies transferrins treatments tropism viral entry virion internalization virus attachment virus entry inhibitors viruses Zika virus |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557448703321 |
Adamson Catherine
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing
| Bioprocess Systems Engineering Applications in Pharmaceutical Manufacturing |
| Autore | Pörtner Ralf |
| Descrizione fisica | 1 online resource (226 p.) |
| Soggetto topico |
History of engineering and technology
Technology: general issues |
| Soggetto non controllato |
Adeno-associated virus
Bayes optimization biopharmaceutical manufacturing bioprocess bioreactor bioreactor characterization biosensor biotherapeutics production cell culture cell culture model Chinese hamster ovary cells CHO DP-12 clonal cell population computational fluid dynamics continuous critical shear stress cryopreservation diabetes Escherichia coli Gaussian processes gene therapy hybrid modeling hydrodynamic gradients hydrodynamic stress inoculum train Kolmogorov length scale machine learning microcarriers model-assisted DoE monitoring monoclonal antibodies multi-objective n/a N−1 perfusion operational space Pareto optimization PAT PEI phenotypic diversity process analytical technology (PAT) process development process intensification quality by design quality by design (QbD) seed train sensors shear stress-guided production smart biomanufacturing soft-sensor spectroscopy spheroid strength surface plasmon resonance (SPR) transfection transient expression uncertainty-based upstream bioprocessing upstream processing vaccines production β-cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595072803321 |
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Pörtner Ralf
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| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Delivery of siRNA Therapeutics
| Drug Delivery of siRNA Therapeutics |
| Autore | Lamberti Gaetano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (288 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
AKT
amphiphilic dendrons angiogenesis antitumor effect aptamers asthma BCL2 BIRC5/survivin breast cancer cancer carbonate apatite cationic cholesterol derivative cationic liposome clinical trials covalent dendrimers delivery drug co-delivery drug delivery endoglin endothelial cells ERBB2 folate folate receptor gene knockdown gene silencing indocyanine green intracellular release iron oxide light-activated release lipid liposome liposomes magnetic nanoparticle methotrexate migration mixed micelles n/a NABDs nanoparticle nanoparticles nanovectors oligonucleotide delivery oral cancer ovarian cancer PAMAM dendrimers pegylation PEI peptide poly(ethylene) imine polyamine polyaspartamide polymer polyplexes proliferation RNA RNAi therapeutics self-assembling siRNA siRNA delivery STAT6 targeted delivery system tumor xenograft tumor-targeting tyrosine-modification VEGFA VEGFR1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557498903321 |
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Lamberti Gaetano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting STAT3 and STAT5 in Cancer
| Targeting STAT3 and STAT5 in Cancer |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (578 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
ADAM17
adoptive T cell therapy AKT androgens apoptosis autoimmune disease autosomal-dominant hyper IgE syndrome Bone Marrow Failure Syndromes breast cancer cancer cancer models cancer progression cancer-stem cell CD38 CD4+ T cells CD8+ T cells cell cycle cell hierarchy chaperones chemotherapy resistance cirrhosis colon cancer companion animals comparative oncology cytokine cytokine receptor signaling dynamic programming endoplasmic reticulum (ER) stress epidermal growth factor receptor (EGF-R) ERK1/2 escape mechanisms gain-of-function mutation glioblastoma glioma growth hormone insensitivity syndrome heat shock proteins hedging hematopoietic cancers hepatitis C virus (HCV) hepatocellular carcinoma (HCC) hepatocyte nuclear factor 4 alpha (HNF4A) immune check point immune suppression immunosuppression immunotherapy inflammation inflammation associated cancer inflammatory hepatocellular adenomas interleukin-6 JAK JAK family of protein tyrosine kinases JAK2 V617F knockout lipopolyplex lung cancer lymphocytes lymphoma M2 macrophages melanoma meta-analysis metalloprotease metastasis microRNA-122 (miR-122) mitochondria MPN mTOR multiple myeloma mutations myeloid cells myeloid leukemia n/a nanoparticle neoplastic stem cells NGS NK cells nuclear factor erythroid 2-related factor 2 (NRF2) nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling ovarian cancer oxidative stress (OS) PD-L1 PEI pharmacological inhibitor pharmacological inhibitors polyethylenimine post-decision state variable prolactin proliferation prostate cancer RHOA risk management S3I-1757 SH2 domain shedding signal transducer and activator of transcription signal transducer and activator of transcription 3 (STAT3) siRNA delivery siRNA/RNAi small-molecule inhibitors solid cancers stabilization STAT STAT transcription factors STAT3 STAT3 inhibitor XIII STAT5 STAT5 signaling STAT5B signaling stem/progenitor cells stemness T-cell large granular lymphocytic leukemia T-cell leukemia T-cell prolymphocytic leukemia T-cells T-PLL targeted therapy targeting therapeutic targeting therapy resistance trans-signaling transaction costs tumor microenvironment tumor necrosis factor alpha (TNFα) tumor suppression tumor-associated macrophages tumor-immune cell interactions tumorigenesis tyrosine kinase 2 unfolded protein response (UPR) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557623503321 |
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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