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Advances in the Treatment of Renal Cell Carcinoma
| Advances in the Treatment of Renal Cell Carcinoma |
| Autore | Reynolds Paul |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (221 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
renal cell carcinoma
autophagy hydroxychloroquine chloroquine ROC-325 cysteine cathepsins cysteine cathepsin inhibitors lysosome renal cancer metastatic renal cell carcinoma immune-based combination therapies network meta-analysis PD-L1 predictive biomarker treatment TKIs mRCC biomarkers soluble factors immunotherapy renal cell carcinoma (RCC) sunitib resistance artesunate (ART) Traditional Chinese Medicine (TCM) growth inhibition ferroptosis reactive oxygen species (ROS) clear cell renal cell carcinoma ccRCC RCC kidney cancer evolution evolutionary trajectory metastatic second line therapy renal cell cancer immune checkpoint inhibitors tyrosine kinase inhibitors individualization genomic signature transcriptomic analysis |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557615503321 |
Reynolds Paul
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (418 p.) |
| Soggetto non controllato |
cancer treatment
extreme learning independent prognostic power AID/APOBEC HP gene inactivation biomarkers biomarker discovery chemotherapy artificial intelligence epigenetics comorbidity score denoising autoencoders protein single-biomarkers gene signature extraction high-throughput analysis concatenated deep feature feature selection differential gene expression analysis colorectal cancer ovarian cancer multiple-biomarkers gefitinib cancer biomarkers classification cancer biomarker mutation hierarchical clustering analysis HNSCC cell-free DNA network analysis drug resistance hTERT variable selection KRAS mutation single-cell sequencing network target skin cutaneous melanoma telomeres Neoantigen Prediction datasets clinical/environmental factors StAR PD-L1 miRNA circulating tumor DNA (ctDNA) false discovery rate predictive model Computational Immunology brain metastases observed survival interval next generation sequencing brain machine learning cancer prognosis copy number aberration mutable motif steroidogenic enzymes tumor mortality tumor microenvironment somatic mutation transcriptional signatures omics profiles mitochondrial metabolism Bufadienolide-like chemicals cancer-related pathways intratumor heterogeneity estrogen locoregionally advanced RNA feature extraction and interpretation treatment de-escalation activation induced deaminase knockoffs R package copy number variation gene loss biomarkers cancer CRISPR overall survival histopathological imaging self-organizing map Network Analysis oral cancer biostatistics firehose Bioinformatics tool alternative splicing biomarkers diseases genes histopathological imaging features imaging TCGA decision support systems The Cancer Genome Atlas molecular subtypes molecular mechanism omics curative surgery network pharmacology methylation bioinformatics neurological disorders precision medicine cancer modeling miRNAs breast cancer detection functional analysis biomarker signature anti-cancer hormone sensitive cancers deep learning DNA sequence profile pancreatic cancer telomerase Monte Carlo mixture of normal distributions survival analysis tumor infiltrating lymphocytes curation pathophysiology GEO DataSets head and neck cancer gene expression analysis erlotinib meta-analysis traditional Chinese medicine breast cancer TCGA mining breast cancer prognosis microarray DNA interaction health strengthening herb cancer genomic instability |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
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Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers Used for the Diagnosis of Diseases
| Biomarkers Used for the Diagnosis of Diseases |
| Autore | Nimse Satish Balasaheb |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (120 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
SERS
LPS bacteria endotoxin lipid A silver nanorods creatinine ZnO nanowires piezo-enzymatic-reaction effect self-powered biosensor immunosensors electrochemical immunosensors biosensors voltammetric immunosensors amperometric immunosensors impedimetric immunosensors eletrochemiluminescent immunosensors cysteine biothiols cystinuria portable fluorimeter bio-imaging cancer bladder cancer prostate cancer urinary biomarkers urinary VOCs machine olfaction GC-IMS GC-TOF-MS cancer markers immune checkpoints PD-1 PD-L1 high-aspect-ratio microfluidic channel parallelogram cross-section monodisperse droplet droplet generation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566479803321 |
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Nimse Satish Balasaheb
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Immunology
| Cancer Immunology |
| Autore | Subramanian Subree |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (316 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
NKG2D
CAR T IL-7 prostate cancer cell therapy CD19-CAR-T B cell aplasia KIR PD-1 inhibitory CAR tumor-infiltrating lymphocytes tumor microenvironment immunotherapy NK cells cancer stem cells (CSCs) antibody-dependent cellular cytotoxicity (ADCC) differentiation cytotoxicity IFN-γ osteoclasts MICA/B mAb DNA methylation RNA methylation S-adenosylmethionine (SAM) cancer innate immunity adaptive immunity T cells m6A PD-L1 resistance immune checkpoints cancer vaccine combination immunotherapy TCR diversity organ transplantation carcinoma epidemiologic studies immunosuppression CTLA-4 Treg cells immune checkpoint inhibitors CD28 antigen-presenting cells IL15 colon cancer melanoma uveal BAP1 anti-PD-1 anti-CTLA-4 TIL classical and endemic Kaposi Sarcoma systemic treatment multi-state modelling treatment free interval chemotherapy interferon triple negative breast cancer immunomodulation bispecific antibody sortase A chemo-enzymatic approach anti-CD20 antibody Fab BiFab colorectal cancer dendritic cells Atypical Chemokine Receptor 4 (ACKR4) T-cell priming immune checkpoint blockade primary liver cancer kynurenine pathway immune evasion indoleamine 2,3 dioxygenase 1 tryptophan 2,3 dioxygenase 2 IDO inhibitor antigen presenting cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557349203321 |
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Subramanian Subree
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Nanomedicine
| Cancer Nanomedicine |
| Autore | Hoskins Clare |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (510 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
antibody drug conjugate (ADC)
PD-L1 tumor spheroid disruption immune modulation doxorubicin graphene oxide adsorption cathepsin D cathepsin L anti-metastatic enzyme cancer therapy nanoparticles targeted delivery system siRNA osteopontin mammary carcinoma mesenchymal stem cells (MSCs) TAT peptide PLGA paclitaxel nano-engineered MSCs orthotopic lung tumor model intracranial glioma immunotherapy CPMV viral nanoparticles in situ vaccine albumin nanoparticles microbubble ultrasound theranostics hepatocellular carcinoma VX2 tumor intra-arterial chemotherapy lung cancer nanomedicine clinical status cancer therapy breast cancer cell signaling active targeting passive targeting EPR effect oncogenes nanoparticle drug delivery ligand tumor targeting biodistribution Mesoporous silica nanoparticle drug delivery system target treatment lanthanide metal hyaluronic acid hyaluronidase drug combination everolimus dual-targeting magnetic nanoparticles monoclonal antibodies nanostructured lipid carrier platelet membrane biomimicry plasmonic photothermal therapy gold nanorods surgery bleeding dogs cats stimuli-responsive DOX SN38 CSCs single-walled carbon nanotubes chirality separation NASH drug-gene delivery near IR hyperspectral imaging plasmonics copper VEGF glioblastoma differentiated neuroblastoma peptidomimetics real-time quantitative polymerase chain reaction (qPCR) actin combinatorial therapy anticancer and antibacterial activity temoporfin drug-in-cyclodextrin-in-liposome hybrid nanoparticles multicellular tumor spheroids cyclodextrins photodynamic therapy article yet reasonably common within the subject discipline antitumor strategy biomimetic core–shell nanoparticles NK cell-derived exosomes folate receptor albumin nanoparticle microfluidic cabazitaxel polydopamine nanoparticles size cytotoxicity iron affinity FA-DABA-SMA self-assembly oncogenic proteins intracellular disruption folic receptor alpha pancreatic cancer parvifloron D albumin erlotinib photodynamic therapy lipid nanoparticles tumor vectorization verteporfin ovarian carcinomatosis spheroids integrin RGD peptide cancer diagnosis radiotherapy hyperthermia therapy biomimetic nanocarrier membrane-wrapped cancer targeted delivery photothermal therapy imaging cancer nanomedicine tumor microenvironment nano–bio interactions clinical translation magnetic nanowires magnetic hyperthermia magnetic actuation magnetic drug targeting titanate nanotubes gold nanoparticles vectorization colloidal stability docetaxel prostate cancer mangiferin anti-topoisomerase activity extracellular vesicles exosomes chemico-physical functionalization loading translational medicine nanotechnology: bioengineering anacardic acid mitoxantrone targeted drug delivery liposomes melanoma apoptosis ascorbic acid angiogenesis epithelial-to-mesenchymal transition hypoxia immunosuppression metabolism nanotherapeutics tumour microenvironment DNA origami liposome remote loading acute toxicity organoids magnetic silica-coated iron oxide nanochains photothermal treatment hyperthermia collagen cellular microenvironment lymphadenectomy magnetometer sentinel lymph node dissection SPION superparamagnetic iron oxide nanoparticles Vδ2 T cells zoledronic acid polymeric nanoconstruct anti-tumor immunity colorectal carcinoma β-cyclodextrin nanosponges BALB-neuT mice brain tumours glioma blood brain barrier polymeric nanoparticles PEGylation dioleoylphosphatidylethanolamine poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer folate oxidation-sensitive release cellular interaction in vitro anti-cancer activity triple negative breast cancer organotin mesoporous silica nanoparticles MDA-MB-231 theranostic nanomaterials nanobiotechnology molecular imaging nanosystems nanomicelles ovarian cancer tumour targeting chemotherapeutics riboflavin vitamin B2 nanomedicines secondary structure mixed micelle pH responsive targeted therapy anti-cancer shear stress flow in vitro therapeutics diagnostics Immunotherapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557114703321 |
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Hoskins Clare
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cross Talk between Lymph Node Lymphatic Endothelial Cells and T Cells in Inflammation and Cancer
| Cross Talk between Lymph Node Lymphatic Endothelial Cells and T Cells in Inflammation and Cancer |
| Autore | Silvia Della Bella |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (100 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Liver Injury
Lymphatic Vessels Lymphatic Vasculature Tumor Microenvironment PD-L1 Antigen Presenting Cells Lymphatic Endothelial Cells T cell trafficking T cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910261134703321 |
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Silvia Della Bella
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Drug Research in China: Selected Papers from the 15-NASMD Conference
| Marine Drug Research in China: Selected Papers from the 15-NASMD Conference |
| Autore | Zhou Xuefeng |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (512 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Antarctic krill (Euphausia superba)
peptide antioxidant activity stability oyster plasma peptidome antimicrobial peptides cytotoxicity actinomycete piericidins absolute configuration Pestalotiopsis heterocornis heterocornols anti-inflammatory activity sponge-derived fungus sclerotides lipodepsipeptide Aspergillus sclerotiorum nasopharyngeal carcinoma AChE inhibitory vascular endothelial cell flavonoid oxidized low-density lipoprotein Nrf2 apoptosis butyrolactone I food allergy metabolism pharmacokinetics actinomycin X2 microbial pigments dyeing silk antibacterial properties PD-L1 virtual screening pharmacophore modeling ADME molecular dynamics xanthones ascidian-derived fungus Diaporthe sp anti-glioma activity antiaging Sonneratia apetala signaling pathway Caenorhabditis elegans mutants coral-derived fungi Aspergillus hiratsukae meroterpenoids antibacterial activity cytotoxic activity deep-sea-derived fungus Aspergillus puniceus isoquinoline alkaloid protein tyrosine phosphatase inhibitor antibacterial Aspergillus sp geodin semisynthesize insecticidal activity Arca inflata antitumor peptide MAPK signaling calmodulin colorectal cancer methicillin-resistant Staphylococcus aureus actinomycin D Streptomyces parvulus mechanism mangrove endophytic Pestalotiopsis Sdy-1 antitumor activity Wnt signaling β-catenin eremophilane sesquiterpenoids mangrove-derived fungus Penicillium sp Oceanapia sponge secondary metabolites biological activities drug design anticancer cyclic pentapeptide galaxamide analogues skipjack tuna (Katsuwonus pelamis) muscle angiotensin-I-converting enzyme (ACE) peptide molecular docking nitric oxide (NO) endothelin-1 (ET-1) Trichoderma longibrachiatum sesquiterpene glycoside antimicrobial activity marine fungi Aspergillus unguis depsides depsidones osteoclast differentiation soft-coral-derived fungus pyranodipyran derivatives tyrosyl DNA phosphodiesterase 1 inhibitory activities fluorescent properties butenolides enantiomers Aspergillus terreus pancreatic lipase NAFLD fucoxanthin adenosine monophosphate-activated protein kinase (AMPK) nuclear factor erythroid-2-related factor 2-mediated (Nrf2) Toll-like receptor 4-mediated (TLR4) Aspergillus flavipes HN4-13 emodin macroporous resin XAD-16 adsorption kinetics and isotherms enrichment tetramic acid derivatives deep-sea fungus clavipitacae Lecanicillium fusisporum chronic kidney disease fucoidan cognitive dysfunction neuroinflammation oxidative stress GSK3β-Nrf2-HO-1 signaling microglial polarization deep-sea actinomycetes aromatic acids oximes antihyperlipidemic phycocyanin microbiota transcriptome IL-17 pathway Hahella prodiginine chejuenlide genome mining LC-MS/MS CDK4/6 marine compounds pharmacophore construction ADMET mm-pbsa |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Marine Drug Research in China |
| Record Nr. | UNINA-9910595071903321 |
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Zhou Xuefeng
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments
| Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments |
| Autore | Uchino Junji |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
non-small cell lung cancer
previously treated patients phase I/II trial chemotherapy docetaxel S-1 immunotherapy rechallenge retrospective analysis pulmonary pleomorphic carcinoma prognostic factor glucose transporter 1 lung cancer multiple cancers metastasis sequencing mutation genomic diagnosis FDG-PET immune checkpoint inhibitor PD-1 prognosis RAD51B methylation PD-L1 expression predictive biomarker PD-1 blockade interstitial lung disease pulmonary fibrosis radiology and other imaging non-small-cell lung cancer epidermal growth factor receptor tyrosine kinase inhibitors TP53 mutations responsiveness targeted therapy network meta-analysis stage IIIA-N2 surgery immune checkpoint inhibitors biomarker nonsmall cell lung cancer HIP1R PD-L1 RUNX1 methylation survival EGFR-TKI T790M osimertinib immune-related adverse events endocrine disorders tumor-bearing patients PD-1 inhibitors PD-L1 inhibitors meta-analysis nivolumab Expanded Access Program real-world data daily practice prognostic factors NSCLC KRAS DNA polymerase beta platinum-based first-line adjuvant chemotherapy β-catenin lung neoplasms nucleotide-diphosphate kinase recurrence unresectable salvage surgery oligometastasis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Non-small Cell Lung Cancer |
| Record Nr. | UNINA-9910557489703321 |
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Uchino Junji
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oncolytic Virus Immunotherapy
| Oncolytic Virus Immunotherapy |
| Autore | Marchini Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (366 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
oncolytic viruses
melanoma immunotherapy checkpoint inhibitors combinatory therapy reovirus oncolytic virus adenovirus oncolytic virotherapy targeting immunogenic cell death αvβ6 integrin oncolytic adenovirus cancer immunotherapy multi-stage immunostimulatory arming HSV-1 clinical trials newcastle disease virus NDV cancer immune checkpoint inhibitor PD-1 PD-L1 CTLA-4 type I interferon herpes simplex virus retargeted virus tropism retargeting tumor checkpoint inhibitor vaccination antigen-agnostic vaccination HER2 parvovirus tumor microenvironment combination therapy glioblastoma pancreatic cancer colorectal cancer measles virus vector engineering immune checkpoint blockade antitumor immune response delivery genetic modification biomarkers personalized oncolyticvirotherapy class I HLA immunosurveillance immunoediting oncogenic signaling RAS DNA methyltransferase inhibitor (DNMTi) viral mimicry epigenetic silencing adoptive T cell therapy CAR T cell pancreatic ductal adenocarcinoma vesicular stomatitis virus small molecule cancer immune therapy cancer therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566462203321 |
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Marchini Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases
| Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases |
| Autore | Rustum Youcef M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (166 p.) |
| Soggetto non controllato |
isoselenourea
malignant chemotherapeutics epigenetics antitumor activity methylseleninic acid mTOR inhibitors tumor heterogeneity hypoxia ER stress melanoma EMT lipid peroxidation immune evasion hypoxia-inducible factors (HIFs) selenium-binding protein 1 glutathione DNA damage hSP56 apoptosis tocopherol anticancer viability SELENBP1 selenium clear-cell renal cell carcinoma microRNAs SBP1 entosis PD-L1 miRNA cancer stem cells cell plasticity disease clear cell renal cell carcinoma HIF head and neck cancer selenium species VEGF STAT3 hypoxia-inducible factor methylselenocysteine anticancer agent Se-containing nanoparticles DNA damage and repair radiation seleno-l-methionine cancer tumor microenvironment methylselenoesters |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346851003321 |
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Rustum Youcef M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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