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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (528 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
ABT-737
acetazolamide acetylcholine adjuvant therapy amoeboid motility angiogenesis apoptosis arthralgia Bcl-2 family BCL2L10 biomarkers BRAF BRAF inhibitor BRAF inhibitors BRAF-mutant melanoma cancer cancer associated fibroblast cancer stem cells carbonic anhydrase cell therapy checkpoint inhibitor cholinergic system combined therapy ctDNA CXCL10 cyclopamine cytokines cytotoxicity diagnosis DOCK4 drug resistance essential oils exosomes extracellular vesicles FAK hedgehog HIPPO HuR immunity immunotherapy interferon invasion ipilimumab lactate dehydrogenase lipid metabolism liquid biopsy liver-directed-therapies machine learning MANS peptide MARCKS mechanism of action melanoma melanoma immune infiltrate melanoma markers melanoma metastasis melanoma PDX melanomagenesis metalloproteinases metastases metastasis metastatic dormancy metastatic therapy metastatic uveal melanoma (mUM) microenvironment microRNAs MITF ML258 motility mucosal melanoma muscarinic receptors n/a nanoparticles nicotinic receptors nivolumab OXPHOS patient stratification PD-1 pembrolizumab phosphorylation plasmacytoid dendritic cells prediction principal component analysis prognosis prognostication protein tyrosine phosphatase PTPs inhibitors Rac1 radiotherapy resistance rheumatoid arthritis sex-hormones sex/gender ShcD adaptor protein siRNA slow cycling phenotype small molecules SOCE STAT3 Support Vector Machine survival target therapy targeted therapy targeted-therapy therapeutic resistance therapy TLR TPC2 tumor microenvironment tumour microenvironment uveal melanoma (UM) WNT5A |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers Used for the Diagnosis of Diseases
| Biomarkers Used for the Diagnosis of Diseases |
| Autore | Nimse Satish Balasaheb |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (120 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
amperometric immunosensors
bacteria bio-imaging biosensors biothiols bladder cancer cancer cancer markers creatinine cysteine cystinuria droplet generation electrochemical immunosensors eletrochemiluminescent immunosensors endotoxin fluorimeter GC-IMS GC-TOF-MS high-aspect-ratio microfluidic channel immune checkpoints immunosensors impedimetric immunosensors lipid A LPS machine olfaction monodisperse droplet parallelogram cross-section PD-1 PD-L1 piezo-enzymatic-reaction effect portable prostate cancer self-powered biosensor SERS silver nanorods urinary biomarkers urinary VOCs voltammetric immunosensors ZnO nanowires |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566479803321 |
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Nimse Satish Balasaheb
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Immunology
| Cancer Immunology |
| Autore | Subramanian Subree |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (316 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adaptive immunity
anti-CD20 antibody anti-CTLA-4 anti-PD-1 antibody-dependent cellular cytotoxicity (ADCC) antigen presenting cells antigen-presenting cells Atypical Chemokine Receptor 4 (ACKR4) B cell aplasia BAP1 BiFab bispecific antibody cancer cancer stem cells (CSCs) cancer vaccine CAR T carcinoma CD19-CAR-T CD28 cell therapy chemo-enzymatic approach chemotherapy classical and endemic Kaposi Sarcoma colon cancer colorectal cancer combination immunotherapy CTLA-4 cytotoxicity dendritic cells differentiation DNA methylation epidemiologic studies Fab IDO inhibitor IFN-γ IL-7 IL15 immune checkpoint blockade immune checkpoint inhibitors immune checkpoints immune evasion immunomodulation immunosuppression immunotherapy indoleamine 2,3 dioxygenase 1 inhibitory CAR innate immunity interferon KIR kynurenine pathway m6A melanoma MICA/B mAb multi-state modelling n/a NK cells NKG2D organ transplantation osteoclasts PD-1 PD-L1 primary liver cancer prostate cancer resistance RNA methylation S-adenosylmethionine (SAM) sortase A systemic treatment T cells T-cell priming TCR diversity TIL treatment free interval Treg cells triple negative breast cancer tryptophan 2,3 dioxygenase 2 tumor microenvironment tumor-infiltrating lymphocytes uveal |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557349203321 |
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Subramanian Subree
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Immunotherapy and The Regulatory Immune System in Blood Cancers: From Mechanisms to Clinical Applications
| Immunotherapy and The Regulatory Immune System in Blood Cancers: From Mechanisms to Clinical Applications |
| Autore | Young Ken H |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 online resource (127 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
Immune checkpoint
Lymphoma microenvironment PD-1 target therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Immunotherapy and The Regulatory Immune System in Blood Cancers |
| Record Nr. | UNINA-9910557224703321 |
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Young Ken H
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments
| Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments |
| Autore | Uchino Junji |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (258 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adjuvant chemotherapy
biomarker chemotherapy daily practice DNA polymerase beta docetaxel EGFR-TKI endocrine disorders epidermal growth factor receptor Expanded Access Program FDG-PET genomic diagnosis glucose transporter 1 HIP1R immune checkpoint inhibitor immune checkpoint inhibitors immune-related adverse events immunotherapy interstitial lung disease KRAS lung cancer lung neoplasms meta-analysis metastasis methylation multiple cancers mutation network meta-analysis nivolumab non-small cell lung cancer non-small-cell lung cancer nonsmall cell lung cancer NSCLC nucleotide-diphosphate kinase oligometastasis osimertinib PD-1 PD-1 blockade PD-1 inhibitors PD-L1 PD-L1 expression PD-L1 inhibitors phase I/II trial platinum-based first-line predictive biomarker previously treated patients prognosis prognostic factor prognostic factors pulmonary fibrosis pulmonary pleomorphic carcinoma RAD51B methylation radiology and other imaging real-world data rechallenge recurrence responsiveness retrospective analysis RUNX1 S-1 salvage surgery sequencing stage IIIA-N2 surgery survival T790M targeted therapy TP53 mutations tumor-bearing patients tyrosine kinase inhibitors unresectable β-catenin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Non-small Cell Lung Cancer |
| Record Nr. | UNINA-9910557489703321 |
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Uchino Junji
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oncolytic Virus Immunotherapy
| Oncolytic Virus Immunotherapy |
| Autore | Marchini Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (366 p.) |
| Soggetto topico |
Clinical and internal medicine
Medicine and Nursing |
| Soggetto non controllato |
adenovirus
adoptive T cell therapy antigen-agnostic vaccination antitumor immune response arming biomarkers cancer cancer immune therapy cancer immunotherapy cancer therapy CAR T cell checkpoint inhibitor checkpoint inhibitors class I HLA clinical trials colorectal cancer combination therapy combinatory therapy CTLA-4 delivery DNA methyltransferase inhibitor (DNMTi) epigenetic silencing genetic modification glioblastoma HER2 herpes simplex virus HSV-1 immune checkpoint blockade immune checkpoint inhibitor immunoediting immunogenic cell death immunostimulatory immunosurveillance immunotherapy measles virus melanoma multi-stage n/a NDV newcastle disease virus oncogenic signaling oncolytic oncolytic adenovirus oncolytic virus oncolytic viruses pancreatic cancer pancreatic ductal adenocarcinoma parvovirus PD-1 PD-L1 personalized oncolyticvirotherapy RAS reovirus retargeted virus small molecule targeting tropism retargeting tumor tumor microenvironment type I interferon vaccination vector engineering vesicular stomatitis virus viral mimicry virotherapy αvβ6 integrin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566462203321 |
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Marchini Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Medical Imaging in Cancers
| Role of Medical Imaging in Cancers |
| Autore | Fanti Stefano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (312 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
18F-FACBC
18F-FDG PET/CT 68Gallium-PSMA PET/CT adipose tissue Adoptive biochemical recurrence biomarker biomarkers bladder cancer breast breast cancer castrate resistant prostate cancer CD8-Positive T-Lymphocytes circulating miRNAs circulating tumor cells computed tomography Computer-assisted diagnosis concurrent chemoradiotherapy consensus CTLA-4 Antigen cystic tumor DCFBC DCFPyL Deauville criteria diagnosis diagnostic imaging diffuse large B-cell lymphoma diffusion diffusion kurtosis imaging diffusion tensor imaging diffusion-weighted imaging dynamic 18F-FDG PET/CT dynamic contrast-enhanced magnetic resonance imaging EBV empyema epistemology FDG FDG-PET/CT follow up glioblastoma gold nanoparticle guidelines head and neck cancer head and neck neoplasms heat shock protein 70 Hodgkin lymphoma Hounsfield unit HPV imaging imaging parameters immune checkpoint inhibitors immunotherapy Immunotherapy International Consensus Guidelines intraductal papillary mucinous neoplasms locally advanced cervical cancer machine learning magnetic resonance imaging malignant pleural mesothelioma mantle cell lymphoma marker mCRPC meningioma Mesothelin meta-analysis metastatic breast cancer miRNA expression molecular imaging Molecular imaging MRI n/a neovascularization neuroimaging non-small-cell lung cancer noninvasive imaging NSCLC nuclear medicine optimal cutoff level ovarian cancer overutilization p16 pancreatic neoplasms pathologic pazopanib PD-1 PD-L1 PDAC PERCIST perfusion PET PET/CT PET/MRI PI-RADS pleural dissemination pleural effusion positron emission tomography positron-emission tomography precision oncology prognosis programmed cell death 1 receptor prostate prostate cancer prostate-specific-antigen PSA kinetics thresholds PSMA PSMA-1007 radiation therapy radioactive tracers radiogenomics radiomic radiomics radionuclide imaging radionuclide therapy Radium-223 receptor status recurrence relapse response assessment response to therapy response to treatment review sdAbs single-photon emission computed tomography soft tissue sarcoma (STS) somatostatin receptor SPECT imaging SPECT/CT spectral-CT squamous cell carcinoma of the head and neck staging survival SUV SUVmax targeted therapy texture analysis Therapy response assessment treatment response triple negative breast cancer two-tissue compartment model upper tract urothelial carcinoma urothelial carcinoma VCAM-1 XOFIGO Yin Yang 1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557432103321 |
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Fanti Stefano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Medical Imaging in Cancers
| Role of Medical Imaging in Cancers |
| Autore | Fanti Stefano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (228 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
18F-FACBC
18F-FDG PET/CT 68Gallium-PSMA PET/CT adipose tissue Adoptive biochemical recurrence biomarker biomarkers bladder cancer breast breast cancer castrate resistant prostate cancer CD8-Positive T-Lymphocytes circulating miRNAs circulating tumor cells computed tomography Computer-assisted diagnosis concurrent chemoradiotherapy consensus CTLA-4 Antigen cystic tumor DCFBC DCFPyL Deauville criteria diagnosis diagnostic imaging diffuse large B-cell lymphoma diffusion diffusion kurtosis imaging diffusion tensor imaging diffusion-weighted imaging dynamic 18F-FDG PET/CT dynamic contrast-enhanced magnetic resonance imaging EBV empyema epistemology FDG FDG-PET/CT follow up glioblastoma gold nanoparticle guidelines head and neck cancer head and neck neoplasms heat shock protein 70 Hodgkin lymphoma Hounsfield unit HPV imaging imaging parameters immune checkpoint inhibitors immunotherapy Immunotherapy International Consensus Guidelines intraductal papillary mucinous neoplasms locally advanced cervical cancer machine learning magnetic resonance imaging malignant pleural mesothelioma mantle cell lymphoma marker mCRPC meningioma Mesothelin meta-analysis metastatic breast cancer miRNA expression molecular imaging Molecular imaging MRI n/a neovascularization neuroimaging non-small-cell lung cancer noninvasive imaging NSCLC nuclear medicine optimal cutoff level ovarian cancer overutilization p16 pancreatic neoplasms pathologic pazopanib PD-1 PD-L1 PDAC PERCIST perfusion PET PET/CT PET/MRI PI-RADS pleural dissemination pleural effusion positron emission tomography positron-emission tomography precision oncology prognosis programmed cell death 1 receptor prostate prostate cancer prostate-specific-antigen PSA kinetics thresholds PSMA PSMA-1007 radiation therapy radioactive tracers radiogenomics radiomic radiomics radionuclide imaging radionuclide therapy Radium-223 receptor status recurrence relapse response assessment response to therapy response to treatment review sdAbs single-photon emission computed tomography soft tissue sarcoma (STS) somatostatin receptor SPECT imaging SPECT/CT spectral-CT squamous cell carcinoma of the head and neck staging survival SUV SUVmax targeted therapy texture analysis Therapy response assessment treatment response triple negative breast cancer two-tissue compartment model upper tract urothelial carcinoma urothelial carcinoma VCAM-1 XOFIGO Yin Yang 1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557309503321 |
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Fanti Stefano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Immunology and Biology of Brain Tumors
| The Immunology and Biology of Brain Tumors |
| Autore | Graner Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (88 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
Addison's disease
adrenal insufficiency bevacizumab cerebral radiation necrosis checkpoint inhibitors craniopharyngioma diffusion tensor imaging exosomes GBM-associated macrophages (GAMs) generalized q-ball imaging glioblastoma multiforme (GBM) glioma high-grade glioma inflammation Interleukin-6 multiple resections oncoantigen oncomiR-21 PD-1 PD-L1 pituitary neuroendocrine tumors STAT3 inhibitor TAM treatment-related effects Treg tumor angiogenesis tumor associate antigen tumor microenvironment (TME) vaccine therapy VEGF |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557665403321 |
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Graner Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy
| The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy |
| Autore | Madureira Patrícia Alexandra Saraiva |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (307 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
3D co-culture
biomarker biomarkers bladder cancer breast cancer cancer cancer acidity cancer cells subpopulations cancer development cancer recurrence cancer stem cells cancer-associated fibroblast (CAF) carcinoma chemotherapy response clinical trials colon cancer cross-presentation CTLA-4 cytokine/chemokine darwinian evolution diclofenac evolutionary therapy extracellular matrix (ECM) feline mammary carcinoma glioblastoma (GB) glioma stem cells (GSC) growth factors head and neck cancer histone modification hyperosmolarity hypoxia Hypoxia Inducible Factor (HIF) immune cell infiltration immunomodulatory roles immunotherapy inhibitor KDM5B koningic acid lung cancer macrophages mammary gland metastasis microenvironment molecular docking molecular subtypes of pancreatic cancer myeloid cells myeloid derived suppressor cells myeloid-derived suppressor cells oxidative stress PAI-1 PAI-2 pancreatic stellate cells PD-1 PD-L1 plasmin plasminogen pre-metastatic niche preclinical modelling pro- and anti-tumor immune cells pro-inflammatory cytokines prognosis prostate cancer radioresistance radiosensitivity radiotherapy radiotherapy dose fractionation reactive oxygen species regulatory T cells repurposing resistance S100A10 S100A10 (p11) signaling pathways spheroid stroma syngeneic model targeted therapy therapeutic resistance TNF-α triple negative tumor growth tumor microenvironment tumor progression tumor-associated macrophages tumour microenvironment uPA uPAR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557354203321 |
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Madureira Patrícia Alexandra Saraiva
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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