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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (528 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
melanoma
invasion WNT5A MARCKS phosphorylation MANS peptide nanoparticles cell therapy tumor microenvironment sex/gender sex-hormones immunity microRNAs immunotherapy BRAF-mutant melanoma BRAF inhibitor mechanism of action targeted therapy tumour microenvironment plasmacytoid dendritic cells lactate dehydrogenase TLR interferon CXCL10 TPC2 HIPPO SOCE metastasis essential oils angiogenesis apoptosis uveal melanoma (UM) metastatic uveal melanoma (mUM) prognostication adjuvant therapy metastatic therapy metastatic dormancy liver-directed-therapies targeted-therapy combined therapy protein tyrosine phosphatase PTPs inhibitors melanoma immune infiltrate BRAF inhibitors microenvironment resistance therapy therapeutic resistance exosomes extracellular vesicles diagnosis prognosis ctDNA liquid biopsy prediction patient stratification BRAF arthralgia rheumatoid arthritis carbonic anhydrase hedgehog cyclopamine small molecules acetazolamide motility metalloproteinases FAK cancer mucosal melanoma nivolumab pembrolizumab ipilimumab radiotherapy cholinergic system acetylcholine muscarinic receptors nicotinic receptors melanoma metastasis ShcD adaptor protein amoeboid motility Rac1 DOCK4 melanoma PDX target therapy cancer stem cells slow cycling phenotype drug resistance OXPHOS lipid metabolism cancer associated fibroblast melanomagenesis biomarkers checkpoint inhibitor PD-1 melanoma markers cytokines machine learning Support Vector Machine principal component analysis BCL2L10 STAT3 cytotoxicity survival ABT-737 Bcl-2 family ML258 HuR MITF metastases siRNA |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers Used for the Diagnosis of Diseases
| Biomarkers Used for the Diagnosis of Diseases |
| Autore | Nimse Satish Balasaheb |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (120 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
SERS
LPS bacteria endotoxin lipid A silver nanorods creatinine ZnO nanowires piezo-enzymatic-reaction effect self-powered biosensor immunosensors electrochemical immunosensors biosensors voltammetric immunosensors amperometric immunosensors impedimetric immunosensors eletrochemiluminescent immunosensors cysteine biothiols cystinuria portable fluorimeter bio-imaging cancer bladder cancer prostate cancer urinary biomarkers urinary VOCs machine olfaction GC-IMS GC-TOF-MS cancer markers immune checkpoints PD-1 PD-L1 high-aspect-ratio microfluidic channel parallelogram cross-section monodisperse droplet droplet generation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566479803321 |
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Nimse Satish Balasaheb
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Immunology
| Cancer Immunology |
| Autore | Subramanian Subree |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (316 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
NKG2D
CAR T IL-7 prostate cancer cell therapy CD19-CAR-T B cell aplasia KIR PD-1 inhibitory CAR tumor-infiltrating lymphocytes tumor microenvironment immunotherapy NK cells cancer stem cells (CSCs) antibody-dependent cellular cytotoxicity (ADCC) differentiation cytotoxicity IFN-γ osteoclasts MICA/B mAb DNA methylation RNA methylation S-adenosylmethionine (SAM) cancer innate immunity adaptive immunity T cells m6A PD-L1 resistance immune checkpoints cancer vaccine combination immunotherapy TCR diversity organ transplantation carcinoma epidemiologic studies immunosuppression CTLA-4 Treg cells immune checkpoint inhibitors CD28 antigen-presenting cells IL15 colon cancer melanoma uveal BAP1 anti-PD-1 anti-CTLA-4 TIL classical and endemic Kaposi Sarcoma systemic treatment multi-state modelling treatment free interval chemotherapy interferon triple negative breast cancer immunomodulation bispecific antibody sortase A chemo-enzymatic approach anti-CD20 antibody Fab BiFab colorectal cancer dendritic cells Atypical Chemokine Receptor 4 (ACKR4) T-cell priming immune checkpoint blockade primary liver cancer kynurenine pathway immune evasion indoleamine 2,3 dioxygenase 1 tryptophan 2,3 dioxygenase 2 IDO inhibitor antigen presenting cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557349203321 |
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Subramanian Subree
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Immunotherapy and The Regulatory Immune System in Blood Cancers: From Mechanisms to Clinical Applications
| Immunotherapy and The Regulatory Immune System in Blood Cancers: From Mechanisms to Clinical Applications |
| Autore | Young Ken H |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (127 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
Immune checkpoint
Lymphoma PD-1 target therapy microenvironment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Immunotherapy and The Regulatory Immune System in Blood Cancers |
| Record Nr. | UNINA-9910557224703321 |
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Young Ken H
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments
| Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments |
| Autore | Uchino Junji |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
non-small cell lung cancer
previously treated patients phase I/II trial chemotherapy docetaxel S-1 immunotherapy rechallenge retrospective analysis pulmonary pleomorphic carcinoma prognostic factor glucose transporter 1 lung cancer multiple cancers metastasis sequencing mutation genomic diagnosis FDG-PET immune checkpoint inhibitor PD-1 prognosis RAD51B methylation PD-L1 expression predictive biomarker PD-1 blockade interstitial lung disease pulmonary fibrosis radiology and other imaging non-small-cell lung cancer epidermal growth factor receptor tyrosine kinase inhibitors TP53 mutations responsiveness targeted therapy network meta-analysis stage IIIA-N2 surgery immune checkpoint inhibitors biomarker nonsmall cell lung cancer HIP1R PD-L1 RUNX1 methylation survival EGFR-TKI T790M osimertinib immune-related adverse events endocrine disorders tumor-bearing patients PD-1 inhibitors PD-L1 inhibitors meta-analysis nivolumab Expanded Access Program real-world data daily practice prognostic factors NSCLC KRAS DNA polymerase beta platinum-based first-line adjuvant chemotherapy β-catenin lung neoplasms nucleotide-diphosphate kinase recurrence unresectable salvage surgery oligometastasis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Non-small Cell Lung Cancer |
| Record Nr. | UNINA-9910557489703321 |
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Uchino Junji
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oncolytic Virus Immunotherapy
| Oncolytic Virus Immunotherapy |
| Autore | Marchini Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (366 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
oncolytic viruses
melanoma immunotherapy checkpoint inhibitors combinatory therapy reovirus oncolytic virus adenovirus oncolytic virotherapy targeting immunogenic cell death αvβ6 integrin oncolytic adenovirus cancer immunotherapy multi-stage immunostimulatory arming HSV-1 clinical trials newcastle disease virus NDV cancer immune checkpoint inhibitor PD-1 PD-L1 CTLA-4 type I interferon herpes simplex virus retargeted virus tropism retargeting tumor checkpoint inhibitor vaccination antigen-agnostic vaccination HER2 parvovirus tumor microenvironment combination therapy glioblastoma pancreatic cancer colorectal cancer measles virus vector engineering immune checkpoint blockade antitumor immune response delivery genetic modification biomarkers personalized oncolyticvirotherapy class I HLA immunosurveillance immunoediting oncogenic signaling RAS DNA methyltransferase inhibitor (DNMTi) viral mimicry epigenetic silencing adoptive T cell therapy CAR T cell pancreatic ductal adenocarcinoma vesicular stomatitis virus small molecule cancer immune therapy cancer therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566462203321 |
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Marchini Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Medical Imaging in Cancers . Volume 1
| Role of Medical Imaging in Cancers . Volume 1 |
| Autore | Fanti Stefano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (312 pages) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
positron emission tomography
head and neck neoplasms neovascularization pathologic PET/CT urothelial carcinoma bladder cancer upper tract urothelial carcinoma survival PET PSMA prostate DCFPyL DCFBC PSMA-1007 ovarian cancer relapse SUVmax targeted therapy prognosis soft tissue sarcoma (STS) pazopanib dynamic 18F-FDG PET/CT SUV two-tissue compartment model magnetic resonance imaging machine learning diffusion perfusion texture analysis squamous cell carcinoma of the head and neck diffusion-weighted imaging malignant pleural mesothelioma pleural dissemination empyema pleural effusion mCRPC SPECT/CT Computer-assisted diagnosis XOFIGO Therapy response assessment circulating miRNAs breast cancer imaging parameters PET/MRI biomarkers triple negative breast cancer VCAM-1 SPECT imaging sdAbs Hounsfield unit computed tomography adipose tissue precision oncology FDG-PET/CT PERCIST metastatic breast cancer prostate cancer 18F-FACBC recurrence meta-analysis review meningioma somatostatin receptor neuroimaging radionuclide therapy breast imaging marker radiomics Yin Yang 1 PDAC Mesothelin noninvasive imaging receptor status molecular imaging nuclear medicine guidelines overutilization epistemology consensus mantle cell lymphoma 18F-FDG PET/CT Deauville criteria Radium-223 FDG castrate resistant prostate cancer programmed cell death 1 receptor diagnostic imaging CTLA-4 Antigen Immunotherapy Adoptive radioactive tracers radionuclide imaging CD8-Positive T-Lymphocytes PI-RADS diffusion kurtosis imaging dynamic contrast-enhanced magnetic resonance imaging 68Gallium-PSMA PET/CT prostate-specific-antigen PSA kinetics thresholds biochemical recurrence optimal cutoff level non-small-cell lung cancer circulating tumor cells immunotherapy response to treatment head and neck cancer HPV EBV p16 Molecular imaging miRNA expression radiogenomics radiomic diagnosis biomarker glioblastoma radiation therapy MRI diffusion tensor imaging Hodgkin lymphoma diffuse large B-cell lymphoma staging response assessment locally advanced cervical cancer concurrent chemoradiotherapy treatment response follow up cystic tumor International Consensus Guidelines intraductal papillary mucinous neoplasms pancreatic neoplasms PD-1 PD-L1 response to therapy NSCLC positron-emission tomography single-photon emission computed tomography immune checkpoint inhibitors gold nanoparticle heat shock protein 70 spectral-CT |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557432103321 |
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Fanti Stefano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Medical Imaging in Cancers . Volume 2
| Role of Medical Imaging in Cancers . Volume 2 |
| Autore | Fanti Stefano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
positron emission tomography
head and neck neoplasms neovascularization pathologic PET/CT urothelial carcinoma bladder cancer upper tract urothelial carcinoma survival PET PSMA prostate DCFPyL DCFBC PSMA-1007 ovarian cancer relapse SUVmax targeted therapy prognosis soft tissue sarcoma (STS) pazopanib dynamic 18F-FDG PET/CT SUV two-tissue compartment model magnetic resonance imaging machine learning diffusion perfusion texture analysis squamous cell carcinoma of the head and neck diffusion-weighted imaging malignant pleural mesothelioma pleural dissemination empyema pleural effusion mCRPC SPECT/CT Computer-assisted diagnosis XOFIGO Therapy response assessment circulating miRNAs breast cancer imaging parameters PET/MRI biomarkers triple negative breast cancer VCAM-1 SPECT imaging sdAbs Hounsfield unit computed tomography adipose tissue precision oncology FDG-PET/CT PERCIST metastatic breast cancer prostate cancer 18F-FACBC recurrence meta-analysis review meningioma somatostatin receptor neuroimaging radionuclide therapy breast imaging marker radiomics Yin Yang 1 PDAC Mesothelin noninvasive imaging receptor status molecular imaging nuclear medicine guidelines overutilization epistemology consensus mantle cell lymphoma 18F-FDG PET/CT Deauville criteria Radium-223 FDG castrate resistant prostate cancer programmed cell death 1 receptor diagnostic imaging CTLA-4 Antigen Immunotherapy Adoptive radioactive tracers radionuclide imaging CD8-Positive T-Lymphocytes PI-RADS diffusion kurtosis imaging dynamic contrast-enhanced magnetic resonance imaging 68Gallium-PSMA PET/CT prostate-specific-antigen PSA kinetics thresholds biochemical recurrence optimal cutoff level non-small-cell lung cancer circulating tumor cells immunotherapy response to treatment head and neck cancer HPV EBV p16 Molecular imaging miRNA expression radiogenomics radiomic diagnosis biomarker glioblastoma radiation therapy MRI diffusion tensor imaging Hodgkin lymphoma diffuse large B-cell lymphoma staging response assessment locally advanced cervical cancer concurrent chemoradiotherapy treatment response follow up cystic tumor International Consensus Guidelines intraductal papillary mucinous neoplasms pancreatic neoplasms PD-1 PD-L1 response to therapy NSCLC positron-emission tomography single-photon emission computed tomography immune checkpoint inhibitors gold nanoparticle heat shock protein 70 spectral-CT |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557309503321 |
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Fanti Stefano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Immunology and Biology of Brain Tumors
| The Immunology and Biology of Brain Tumors |
| Autore | Graner Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (88 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
vaccine therapy
oncoantigen tumor associate antigen tumor angiogenesis high-grade glioma pituitary neuroendocrine tumors VEGF Treg TAM PD-1 PD-L1 tumor microenvironment (TME) glioblastoma multiforme (GBM) GBM-associated macrophages (GAMs) exosomes oncomiR-21 STAT3 inhibitor glioma diffusion tensor imaging generalized q-ball imaging treatment-related effects multiple resections adrenal insufficiency Addison’s disease bevacizumab cerebral radiation necrosis craniopharyngioma inflammation checkpoint inhibitors Interleukin-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557665403321 |
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Graner Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy
| The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy |
| Autore | Madureira Patrícia Alexandra Saraiva |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (307 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
hypoxia
macrophages colon cancer tumor microenvironment immune cell infiltration prognosis feline mammary carcinoma PD-1 PD-L1 CTLA-4 TNF-α biomarkers immunotherapy cancer histone modification inhibitor KDM5B molecular docking repurposing cancer acidity hyperosmolarity cross-presentation tumour microenvironment syngeneic model prostate cancer radiotherapy preclinical modelling myeloid-derived suppressor cells biomarker stroma cancer-associated fibroblast (CAF) extracellular matrix (ECM) cytokine/chemokine growth factors pro- and anti-tumor immune cells immunomodulatory roles radiotherapy dose fractionation radioresistance radiosensitivity breast cancer S100A10 (p11) tumor growth tumor progression metastasis carcinoma mammary gland triple negative pre-metastatic niche pro-inflammatory cytokines clinical trials evolutionary therapy darwinian evolution cancer cells subpopulations diclofenac koningic acid spheroid 3D co-culture microenvironment resistance myeloid cells cancer development molecular subtypes of pancreatic cancer chemotherapy response pancreatic stellate cells regulatory T cells tumor-associated macrophages myeloid derived suppressor cells glioblastoma (GB) Hypoxia Inducible Factor (HIF) glioma stem cells (GSC) oxidative stress reactive oxygen species plasmin plasminogen S100A10 uPA uPAR PAI-1 PAI-2 cancer stem cells cancer recurrence therapeutic resistance signaling pathways targeted therapy head and neck cancer lung cancer bladder cancer |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557354203321 |
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Madureira Patrícia Alexandra Saraiva
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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