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Preclinical Evaluation of Lipid-Based Nanosystems
| Preclinical Evaluation of Lipid-Based Nanosystems |
| Autore | Silva Ana Catarina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (351 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
nanostructured lipid carriers (NLC)
formulation optimization rivastigmine quality by design (QbD) nasal route nose-to-brain N-alkylisatin liposome urokinase plasminogen activator PAI-2 SerpinB2 breast cancer liposomes target delivery nanosystem FZD10 protein colon cancer therapy supersaturation silica-lipid hybrid spray drying lipolysis lipid-based formulation fenofibrate mesoporous silica oral drug delivery hyaluronic acid drug release light activation stability mobility biocorona dissolution enhancement phospholipids solid dosage forms porous microparticles nanoemulsion(s) phase-behavior DoE D-optimal design vegetable oils non-ionic surfactants efavirenz flaxseed oil nanostructured lipid carriers nanocarrier docohexaenoic acid neuroprotection neuroinflammation fluconazole Box‒Behnken design nanotransfersome ulcer index zone of inhibition rheological behavior ex vivo permeation nanomedicine cancer doxorubicin melanoma drug delivery ultrasound contrast agents phospholipid coating ligand distribution cholesterol acoustic response microbubble lipid phase dialysis ammonia intoxication cyanocobalamin vitamin B12 atopic dermatitis psoriasis transferosomes lipid vesicles skin topical delivery oligonucleotide self-emulsifying drug delivery systems hydrophobic ion pairing intestinal permeation enhancers Caco-2 monolayer clarithromycin solid lipid nanoparticles optimization permeation pharmacokinetics follicular targeting dexamethasone alopecia areata lipomers lipid polymer hybrid nanocapsules biodistribution skin ethyl cellulose |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557544303321 |
Silva Ana Catarina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Fibrinolytic System in Health and Disease
| The Role of Fibrinolytic System in Health and Disease |
| Autore | Kwaan Hau C |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
COVID-19
fibrinolysis renin-aldosterone-angiotensin-system (RAAS) plasminogen activator inhibitor 1 (PAI-1) urokinase plasminogen activator urokinase plasminogen activator receptor plasminogen activator inhibitor-1 acute lung injury and repair and pleural injury and pleural organization PAI-1 cardiovascular disease cancer inflammation fibrosis aging obstructive sleep apnoea OSA coagulation platelets brown adipose tissue obesity plasminogen activation immune response thrombin activatable fibrinolysis inhibitor TAFI proCPU proCPB proCPR carboxypeptidase uPA uPAR PA system tissue-type plasminogen activator (tPA) urokinase-type plasminogen activator (uPA) neurodegeneration thrombin shear clot retraction Factor XIII clot stability NETs plasmin plasminogen activator PAI-2 antiplasmin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213103321 |
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Kwaan Hau C
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy
| The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy |
| Autore | Madureira Patrícia Alexandra Saraiva |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (307 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
hypoxia
macrophages colon cancer tumor microenvironment immune cell infiltration prognosis feline mammary carcinoma PD-1 PD-L1 CTLA-4 TNF-α biomarkers immunotherapy cancer histone modification inhibitor KDM5B molecular docking repurposing cancer acidity hyperosmolarity cross-presentation tumour microenvironment syngeneic model prostate cancer radiotherapy preclinical modelling myeloid-derived suppressor cells biomarker stroma cancer-associated fibroblast (CAF) extracellular matrix (ECM) cytokine/chemokine growth factors pro- and anti-tumor immune cells immunomodulatory roles radiotherapy dose fractionation radioresistance radiosensitivity breast cancer S100A10 (p11) tumor growth tumor progression metastasis carcinoma mammary gland triple negative pre-metastatic niche pro-inflammatory cytokines clinical trials evolutionary therapy darwinian evolution cancer cells subpopulations diclofenac koningic acid spheroid 3D co-culture microenvironment resistance myeloid cells cancer development molecular subtypes of pancreatic cancer chemotherapy response pancreatic stellate cells regulatory T cells tumor-associated macrophages myeloid derived suppressor cells glioblastoma (GB) Hypoxia Inducible Factor (HIF) glioma stem cells (GSC) oxidative stress reactive oxygen species plasmin plasminogen S100A10 uPA uPAR PAI-1 PAI-2 cancer stem cells cancer recurrence therapeutic resistance signaling pathways targeted therapy head and neck cancer lung cancer bladder cancer |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557354203321 |
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Madureira Patrícia Alexandra Saraiva
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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