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Acetaldehyde-related pathology [[electronic resource] ] : bridging the trans-disciplinary divide / / [chair, Peter Emery]
| Acetaldehyde-related pathology [[electronic resource] ] : bridging the trans-disciplinary divide / / [chair, Peter Emery] |
| Edizione | [8th ed.] |
| Pubbl/distr/stampa | Chichester ; ; Hoboken, N.J., : John Wiley, 2007 |
| Descrizione fisica | 1 online resource (287 p.) |
| Disciplina | 615.952 |
| Altri autori (Persone) |
EmeryPeter <1953->
ChadwickDerek GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico | Acetaldehyde - Toxicology |
| Soggetto genere / forma | Electronic books. |
| Soggetto non controllato |
Acetaldehyde related pathology
Trans-disciplinary divide Novartis |
| ISBN |
1-280-85598-3
9786610855988 0-470-51184-2 0-470-51183-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Acetaldehyde-Related Pathology: Bridging the Trans-Disciplinary Divide; Contents; Chair's introduction; Acetaldehyde generating enzyme systems: roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes; Removal of acetaldehyde from the body; Acetaldehyde, polymorphisms and the cardiovascular system; Acetaldehyde and alcoholic cardiomyopathy: lessons from the ADH and ALDH2 transgenic models; Interrelationship between alcohol, smoking, acetaldehyde and cancer; Effects of acetaldehyde on human airway constriction and inflammation
The role of acetaldehyde in alcohol-associated cancer of the gastrointestinal tractThe determination of acetaldehyde in exhaled breath; Ethanol and acetaldehyde: in vivo quantitation and effects on cholinergic function in rat brain; Pharmacological treatments and strategies for reducing oral and intestinal acetaldehyde; Alcoholic myopathy and acetaldehyde; Acetaldehyde adducts in circulation; General discussion; Pancreatic MAP kinase pathways and acetaldehyde; Acetaldehyde alters MAP kinase signalling and epigenetic histone modifications in hepatocytes Endogenous a-oxoaldehydes and formation of protein and nucleotide advanced glycation endproducts in tissue damageMeasurement of acetaldehyde: what levels occur naturally and in response to alcohol?; Final discussion; Contributors Index; Subject index |
| Record Nr. | UNINA-9910143705803321 |
| Chichester ; ; Hoboken, N.J., : John Wiley, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Acetaldehyde-related pathology [[electronic resource] ] : bridging the trans-disciplinary divide / / [chair, Peter Emery]
| Acetaldehyde-related pathology [[electronic resource] ] : bridging the trans-disciplinary divide / / [chair, Peter Emery] |
| Edizione | [8th ed.] |
| Pubbl/distr/stampa | Chichester ; ; Hoboken, N.J., : John Wiley, 2007 |
| Descrizione fisica | 1 online resource (287 p.) |
| Disciplina | 615.952 |
| Altri autori (Persone) |
EmeryPeter <1953->
ChadwickDerek GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico | Acetaldehyde - Toxicology |
| Soggetto non controllato |
Acetaldehyde related pathology
Trans-disciplinary divide Novartis |
| ISBN |
1-280-85598-3
9786610855988 0-470-51184-2 0-470-51183-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Acetaldehyde-Related Pathology: Bridging the Trans-Disciplinary Divide; Contents; Chair's introduction; Acetaldehyde generating enzyme systems: roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes; Removal of acetaldehyde from the body; Acetaldehyde, polymorphisms and the cardiovascular system; Acetaldehyde and alcoholic cardiomyopathy: lessons from the ADH and ALDH2 transgenic models; Interrelationship between alcohol, smoking, acetaldehyde and cancer; Effects of acetaldehyde on human airway constriction and inflammation
The role of acetaldehyde in alcohol-associated cancer of the gastrointestinal tractThe determination of acetaldehyde in exhaled breath; Ethanol and acetaldehyde: in vivo quantitation and effects on cholinergic function in rat brain; Pharmacological treatments and strategies for reducing oral and intestinal acetaldehyde; Alcoholic myopathy and acetaldehyde; Acetaldehyde adducts in circulation; General discussion; Pancreatic MAP kinase pathways and acetaldehyde; Acetaldehyde alters MAP kinase signalling and epigenetic histone modifications in hepatocytes Endogenous a-oxoaldehydes and formation of protein and nucleotide advanced glycation endproducts in tissue damageMeasurement of acetaldehyde: what levels occur naturally and in response to alcohol?; Final discussion; Contributors Index; Subject index |
| Record Nr. | UNINA-9910830629903321 |
| Chichester ; ; Hoboken, N.J., : John Wiley, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Mast cells and basophils [[electronic resource] ] : development, activation and roles in allergic/autoimmune disease
| Mast cells and basophils [[electronic resource] ] : development, activation and roles in allergic/autoimmune disease |
| Pubbl/distr/stampa | Chichester, : John Wiley, 2005 |
| Descrizione fisica | 1 online resource (275 p.) |
| Disciplina | 616.079 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Mast cells
Basophils |
| Soggetto genere / forma | Electronic books. |
| Soggetto non controllato |
Autoimmune disease
Allergic disease Novartis |
| ISBN |
1-280-30875-3
9786610308750 0-470-03344-4 0-470-03051-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MAST CELLS AND BASOPHILS: DEVELOPMENT, ACTIVATION AND ROLES IN ALLERGIC/AUTOIMMUNE DISEASE; Contents; Participants; Chair's introduction; MITF and SgIGSF: an essential transcription factor and its target adhesion molecule for development and survival of mast cells; Discussion; Immune sensitization in the skin is enhanced by antigen-independent effects of IgE on mast cells; Discussion; The role of Src family kinases in mast cell effector function; Discussion; RasGRP4 in mast-cell signalling and disease susceptibility; Discussion
Regulation of mast cell secretory response to the type I Fce receptor: inhibitory elements and desensitisationDiscussion; General discussion I; IgE regulation of mast cell survival and function; Discussion; RabGEF1, a negative regulator of Ras signalling, mast cell activation and skin inflammation; Discussion; Role of CC chemokines and their receptors in multiple aspects of mast cell biology: comparative protein profiling of FceRI- and/or CCR1-engaged mast cells using protein chip technology; Discussion; The role of phosphoinositide-3-kinase in mast cell homing to the gastrointestinal tract DiscussionThe mast cell and the cysteinyl leukotrienes; Discussion; Regulation of gene expression in mast cells: micro-RNA expression and chromatin structural analysis of cytokine genes; Discussion; The involvement of Bcl-2 in mast cell apoptosis; Discussion; General discussion II; General discussion III; Mast cells in autoantibody responses and arthritis; Discussion; MASTering the immune response: mast cells in autoimmunity; Discussion; Mastocytosis; Discussion; Index of contributors; Subject index |
| Record Nr. | UNINA-9910143702703321 |
| Chichester, : John Wiley, 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Mast cells and basophils [[electronic resource] ] : development, activation and roles in allergic/autoimmune disease
| Mast cells and basophils [[electronic resource] ] : development, activation and roles in allergic/autoimmune disease |
| Pubbl/distr/stampa | Chichester, : John Wiley, 2005 |
| Descrizione fisica | 1 online resource (275 p.) |
| Disciplina | 616.079 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Mast cells
Basophils |
| Soggetto non controllato |
Autoimmune disease
Allergic disease Novartis |
| ISBN |
1-280-30875-3
9786610308750 0-470-03344-4 0-470-03051-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MAST CELLS AND BASOPHILS: DEVELOPMENT, ACTIVATION AND ROLES IN ALLERGIC/AUTOIMMUNE DISEASE; Contents; Participants; Chair's introduction; MITF and SgIGSF: an essential transcription factor and its target adhesion molecule for development and survival of mast cells; Discussion; Immune sensitization in the skin is enhanced by antigen-independent effects of IgE on mast cells; Discussion; The role of Src family kinases in mast cell effector function; Discussion; RasGRP4 in mast-cell signalling and disease susceptibility; Discussion
Regulation of mast cell secretory response to the type I Fce receptor: inhibitory elements and desensitisationDiscussion; General discussion I; IgE regulation of mast cell survival and function; Discussion; RabGEF1, a negative regulator of Ras signalling, mast cell activation and skin inflammation; Discussion; Role of CC chemokines and their receptors in multiple aspects of mast cell biology: comparative protein profiling of FceRI- and/or CCR1-engaged mast cells using protein chip technology; Discussion; The role of phosphoinositide-3-kinase in mast cell homing to the gastrointestinal tract DiscussionThe mast cell and the cysteinyl leukotrienes; Discussion; Regulation of gene expression in mast cells: micro-RNA expression and chromatin structural analysis of cytokine genes; Discussion; The involvement of Bcl-2 in mast cell apoptosis; Discussion; General discussion II; General discussion III; Mast cells in autoantibody responses and arthritis; Discussion; MASTering the immune response: mast cells in autoimmunity; Discussion; Mastocytosis; Discussion; Index of contributors; Subject index |
| Record Nr. | UNINA-9910830564403321 |
| Chichester, : John Wiley, 2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Tinkering [[electronic resource] ] : the microevolution of development / / [editors: Gregory Bock and Jamie Goode]
| Tinkering [[electronic resource] ] : the microevolution of development / / [editors: Gregory Bock and Jamie Goode] |
| Pubbl/distr/stampa | Chichester ; ; Hoboken, NJ, : John Wiley & Sons, 2007 |
| Descrizione fisica | 1 online resource (301 p.) |
| Disciplina | 572.8 |
| Altri autori (Persone) |
BockGregory
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Molecular biology
Molecular evolution |
| Soggetto non controllato |
Tinkering
Microevolution Development Novartis |
| ISBN |
1-280-90082-2
9786610900824 0-470-31939-9 0-470-31940-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Tinkering: The Microevolution of Development; Contents; The evolutionary developmental biology of tinkering: an introduction to the challenge; Tinkering: a conceptual and historical evaluation; DISCUSSION; Tinkering: new embryos from old-rapidly and cheaply; DISCUSSION; The relationship between development and evolution through heritable variation; DISCUSSION; Genetic networks as transmitting and amplifying devices for natural genetic tinkering; DISCUSSION; Butterfly eyespot patterns and how evolutionary tinkering yields diversity; DISCUSSION; GENERAL DISCUSSION I
Tinkering with transcription factor proteins: the role of transcription factor adaptation in developmental evolutionDISCUSSION; Tinkering with constraints in the evolution of the vertebrate limb anterior-posterior polarity; DISCUSSION; Affecting tooth morphology and renewal by fine-tuning the signals mediating cell and tissue interactions; DISCUSSION; GENERAL DISCUSSION II; Evolution of covariance in the mammalian skull; DISCUSSION; The developmental genetics of microevolution; DISCUSSION; The economy of tinkering mammalian teeth; DISCUSSION Pelvic skeleton reduction and Pitx1 expression in threespine stickleback populationsDISCUSSION; Using patterns of fin and limb phylogeny to test developmental- evolutionary scenarios; DISCUSSION; Craniofacial variation and developmental divergence in primate and human evolution; DISCUSSION; Contributor Index; Subject Index |
| Record Nr. | UNINA-9910143676903321 |
| Chichester ; ; Hoboken, NJ, : John Wiley & Sons, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Tinkering [[electronic resource] ] : the microevolution of development / / [editors: Gregory Bock and Jamie Goode]
| Tinkering [[electronic resource] ] : the microevolution of development / / [editors: Gregory Bock and Jamie Goode] |
| Pubbl/distr/stampa | Chichester ; ; Hoboken, NJ, : John Wiley & Sons, 2007 |
| Descrizione fisica | 1 online resource (301 p.) |
| Disciplina | 572.8 |
| Altri autori (Persone) |
BockGregory
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Molecular biology
Molecular evolution |
| Soggetto non controllato |
Tinkering
Microevolution Development Novartis |
| ISBN |
1-280-90082-2
9786610900824 0-470-31939-9 0-470-31940-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Tinkering: The Microevolution of Development; Contents; The evolutionary developmental biology of tinkering: an introduction to the challenge; Tinkering: a conceptual and historical evaluation; DISCUSSION; Tinkering: new embryos from old-rapidly and cheaply; DISCUSSION; The relationship between development and evolution through heritable variation; DISCUSSION; Genetic networks as transmitting and amplifying devices for natural genetic tinkering; DISCUSSION; Butterfly eyespot patterns and how evolutionary tinkering yields diversity; DISCUSSION; GENERAL DISCUSSION I
Tinkering with transcription factor proteins: the role of transcription factor adaptation in developmental evolutionDISCUSSION; Tinkering with constraints in the evolution of the vertebrate limb anterior-posterior polarity; DISCUSSION; Affecting tooth morphology and renewal by fine-tuning the signals mediating cell and tissue interactions; DISCUSSION; GENERAL DISCUSSION II; Evolution of covariance in the mammalian skull; DISCUSSION; The developmental genetics of microevolution; DISCUSSION; The economy of tinkering mammalian teeth; DISCUSSION Pelvic skeleton reduction and Pitx1 expression in threespine stickleback populationsDISCUSSION; Using patterns of fin and limb phylogeny to test developmental- evolutionary scenarios; DISCUSSION; Craniofacial variation and developmental divergence in primate and human evolution; DISCUSSION; Contributor Index; Subject Index |
| Record Nr. | UNINA-9910830693403321 |
| Chichester ; ; Hoboken, NJ, : John Wiley & Sons, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||