Advances in Ginsenosides |
Autore | Chen Jen-Tsung |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (264 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
Ginseng berries
UPLC-QTOF/MS HR-MAS NMR spectroscopy ginsenoside primary metabolite notoginseng leaf triterpenes HMGB1 cerebral ischemia and reperfusion injury inflammation MAPK NF-κB Panax ginseng wild ginseng pharmacopuncture safety clinical trials ocotillol type ginsenoside epimers stereoselective ADME characteristics molecular docking analysis homology modeling molecular interaction Rg3 Th17 RORγt EAE Lactobacillus ginsenosidimutans complete genome sequence novel glycoside hydrolases bioconversion recombinant enzyme ginsenoside Rg3(S) gram unit production Asian ginseng American ginseng Panax quinquefolium L. ginsenosides anti-inflammation pro-resolving ginseng macrophage M2 polarization ginsenoside CK neurogenesis cell proliferation neuroprotection dammarane-type triterpene saponin ginsenoside MT1 transglycosylation biotransformation biotechnology Anxa2 epithelial-mesenchymal transition (20S)G-Rh2 bioreactor cell suspension hairy root polyploidy protoplast Panax sp polysaccharides allergy immune system compound M1 hepatoprotective anti-cancer anti-diabetic |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557766503321 |
Chen Jen-Tsung | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Anticancer Properties of Natural and Derivative Products |
Autore | Lupiáñez José Antonio |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (312 p.) |
Soggetto topico | Research & information: general |
Soggetto non controllato |
total phenolic content
total flavonoid content GC-MS DPPH antioxidant anticancer agent anti-inflammatory agent gingival fibroblasts oral cancer natural extract Adenosma bracteosum extract anti-cancer cell line isolated compounds caspase-3 bioactive compounds metabolites wine grapes breast cancer chemoprevention chemotherapy squamous cell carcinoma Moringa oleifera 3-hydroxy-β-ionone antioxidant activity antioxidant enzymes anti-proliferative activity maslinic acid melanoma Olea europaea L. ROS levels photodynamic therapy cancer photosensitiser natural compounds Elaeagnus angustifolia EMT apoptosis AKT/PI3K signaling pathway human hepatocarcinoma HepG2 cells migration activity proliferation oxidative stress ROS level uvaol lung metastases in vivo complementary medicine medicinal mushrooms triterpenoic acid tormentic acid betulinic acid oleanolic acid rhodamine B cytotoxicity hepatocellular carcinoma (HCC) Pogostemon cablin (PPa extract) cell cycle synergism natural photosensitive compounds anticancer activity hypericin emodin quinizarin danthron interaction DNA glioblastoma (GBM) lactucopicrin (LCTP) temozolomide (TMZ) autophagy NF-κB p62/SQSM1 natural product therapeutic triglyceride xenograft study Caveolin-1 actin cytoskeleton betulin glycoconjugates click chemistry 1,3-dipolar cycloaddition |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557370303321 |
Lupiáñez José Antonio | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Antimicrobial Peptides Aka Host Defense Peptides – From Basic Research to Therapy |
Autore | Petrlova Jitka |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (226 p.) |
Soggetto topico |
Research & information: general
Chemistry |
Soggetto non controllato |
ECP
AMPs infection murine model Gram-negative bacteria LPS host defense peptides monocytes neutrophils neutrophil–monocyte interaction extracellular traps host defense peptide innate immunity NF-κB poly I:C toll-like receptor 3 mucus of Cornu aspersum peptide fraction MW < 10 kDa Escherichia coli NBIMCC 8785 SEM fluorescence and digital assays antibacterial effect oral cavity human cathelicidin antimicrobial peptides immunomodulation oncolytic peptides cancer membrane integrity bulky non-nature amino acid DAMPs drug design antimicrobial peptidomimetic hydrogel-based system hyaluronic acid anti-infective activity skin infections antimicrobial peptide expression intein self-cleavage cecropin-like apolipoprotein E host defense aggregation body fluid AMP interaction network chemical barrier cationic antimicrobial peptides length dependent activity antimicrobial activity hemolysis vesicle leakage solid-state 31P-, 15N- and 19F-NMR β-stranded peptides β-sheets structure and orientation of peptides in membranes |
ISBN | 3-0365-5820-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910639991103321 |
Petrlova Jitka | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Antitumor and Anti-HIV Agents from Natural Products |
Autore | Nakagawa-Goto Kyoko |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (338 p.) |
Soggetto topico | Research & information: general |
Soggetto non controllato |
natural phaeosphaeride A
antitumor activity human tumor cell lines HEF cell line acute toxicity aspidosperma-type monoterpenoid indole alkaloids antiproliferative activity tubulin inhibitor Bousigonia mekongensis ursolic acid DOTA triterpenoids cytotoxicity diterpenoid alkaloids human tumor cells lipojesaconitine delcosine delpheline kobusine pseudokobusine BRAF inhibitor Mentha aquatica var. Kenting Water Mint essential oil chemoprevention two-stage skin carcinogenesis melanoma curcumin analog apoptosis oxidative stress drug–drug interaction tamoxifen taxol cisplatin Artemisia absinthium L. antioxidants total phenolic content melanoma and breast cancer cell line HaCaT cells inflammation breast cancer cell cycle flavonoids reactive oxygen species tumor suppression antiretroviral agents anti-HIV marine metabolites natural products drug development Ivalin Carpesium divaricatum hepatocellular carcinoma mitochondria-mediated apoptosis NF-κB Hernandia nymphaeifolia butanolides lignan glycosides coumarins antiangiogenic cancer natural agents chemistry medicine cancer stem cell cervical cancer pterostilbene resveratrol caffeic acid cancer multidrug resistance P-glycoprotein phenolic acid oxypeucedanin Angelica dahurica antiproliferation G2/M phase cell cycle arrest p53 SK-Hep-1 hepatoma cells allyl isothiocyanate benzyl isothiocyanate sulforaphane phenethyl isothiocyanate bladder cancer quercetin oral squamous cell carcinoma cells metastasis cell cycle arrest epithelial-to-mesenchymal transition matrix metalloproteinase transforming growth factor-β1 β-lapachone |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557504803321 |
Nakagawa-Goto Kyoko | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products |
Autore | Fabiani Roberto |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (344 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557419703321 |
Fabiani Roberto | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products : Volume 2 |
Autore | Fabiani Roberto |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (300 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Antitumoral Properties of Natural Products |
Record Nr. | UNINA-9910557531303321 |
Fabiani Roberto | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Authenticity of Honey: Characterization, Bioactivities and Sensorial Properties |
Autore | Escuredo Olga |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (214 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
honey
authentication physicochemical parameters PCA characterization Algerian honey botanical origin biogeographical origin safflower (Carthamus tinctorius L.) honey chemical analysis anti-inflammatory antioxidant NF-κB Nrf-2 hydrogen peroxide functional food bacterial pathogen commercial honey quality standard Babors Kabylia sensorial properties melissopalynology quality parameters multivariate analysis quality control NIR modified partial least squares linear discriminant analysis Silicoflagellata diatoms pollen spores autumn heather honey Erica manipuliflora Salisb volatiles gas chromatography-mass spectrometry solid-phase microextraction optimization response surface methodology polyphenols phenolic profile total phenolic content antioxidant activity liquid chromatography tandem mass spectrometry principal components analysis light stable isotope mass spectrometry ultra-high performance liquid chromatography high resolution mass spectrometry nuclear magnetic resonance principal component analysis floral origins entomological origin mitochondrial DNA NADH dehydrogenase 2 PCR honeydew pine honey sensory evaluation bioactivity antimicrobial |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Authenticity of Honey |
Record Nr. | UNINA-9910580206003321 |
Escuredo Olga | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Cellular Oxidative Stress |
Autore | Marino Angela |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (529 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
neuroinflammation
clinical palmitoylethanolamide luteolin co-ultramicronization CNS pathology adaptive immune response cell homeostasis legumes liver hepatic steatosis lipid dyshomeostasis ROS traumatic brain injury palmitoylethanolamide (PEA) therapeutic strategies oxidative stress RNA-Seq RPE Retinitis pigmentosa A2E diabetes glucose exposure Band 3 protein erythrocytes SO42− 4-hydroxy-2-nonenal 3-glutathionyl-4-hydroxynonanal astrocytoma cells soy soybeans soy foods antioxidants reactive oxygen species cardiovascular diseases cancer paw edema cashew nuts antioxidant inflammation polyphenols analgesic d-Galactose glycation SO42− uptake anion exchange diseases immune system NF-κB cigarette smoke extract nasal fibroblasts tissue inhibitor of metalloproteinases matrix metalloproteinase steroids Plasmodium falciparum syk kinase inhibitors artemisinin derivatives hemichromes cellular redox state mitochondrial function cisplatin nephrotoxicity acute pancreatitis obesity nitrosative stress PGC-1α microparticles vesiculation band 3 tert-Bytyl hydroperoxide t-BOOH nitric oxide donor calcium ionophore A23187 age-related macular degeneration (AMD) diet Substance-P adipose-derived stem cells paracrine factors epilepsy status epilepticus Trolox HeLa prooxidant AVD apoptosis neurodegeneration ncRNA miRNA tRNA fragments lncRNA circRNA preeclampsia hemostasis platelets coagulation fish mucosal immunity nasal immunity peroxide vitamin C NAC immunosenescence T cells vaccination aging microvascular permeability bradykinin interleukin 1β NADPH oxidase simvastatin molecular hydrogen autophagy matrix metalloproteinases reactive oxygen species (ROS) phytochemicals dietary chemicals natural compounds programmed cell death anoikis ferroptosis pyroptosis |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557338703321 |
Marino Angela | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Coumarin and Its Derivatives |
Autore | Matos Maria João |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (406 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
coumarin
hydroxyl-modified coumarin photophysical thermal and structural characterization Glycyrrhiza uralensis glycyrol liquiritigenin cholinesterases human monoamine oxidases kinetics docking simulation chalcone neurodegenerative diseases adenosine receptors binding affinity docking 4-hydroxy-7-methoxycoumarin macrophage inflammation NF-κB MAPK calanolides pseudocalanolides calanolide A Calophyllum Calophyllaceae anti-HIV reverse transcriptase non-nucleoside reverse transcriptase inhibitors (NNRTIs) osthole umbelliferone esculin 4-hydroxycoumarin sorafenib apoptosis autophagy Yin Chen Hao constitutive androstane receptor scoparone coumarins quorum sensing QS inhibitors plant-derived molecules Chromobacterium violaceum immunoproteasome psoralen core non-peptidic electrophilic compounds warhead scan inflammatory bowel disease isocoumarin Crohn's disease ulcerative colitis glutathione oxidative stress complementary therapies intestinal inflammation benzopyrones five-membered aromatic heterocycles furan pyrrole thiophene selenophen dihydrocoumarin-fused dihydropyranones 3-aroylcoumarines benzyl 2,3-butadienoate 6'-(4-biphenyl)-β-iso-cinchonine biological applications drug discovery fluorescent probes warfarin acenocoumarol mechanical valve time in therapeutic range anticoagulation Ruta chalepensis Rutaceae chalepin chalepensin bioactivity biosynthesis coumarin3-carboxamides pyranocoumarins anticancer activity antibacterial activity free radical polymerization LED photocomposites direct laser write analytical methods model plant natural genetic variation natural products simple coumarins chalcocoumarin MAO-B molecular dynamics in silico studies dye-sensitized solar cells coumarin dyes thieno [3,2-b] thiophene charge transfer ethynylaryl esculetin antiplatelet activity impedance aggregometry COX polyphenols pyrazole imidazole thiazole oxazole triazole thiadiazole curcumin curcumin-coumarin hybrids neuroprotection monoamine oxidase inhibition cholinesterase inhibition scavenging activity Escherichia coli biotransformation ferulenol structural annotation in silico tools |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557577003321 |
Matos Maria João | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology |
Autore | Fioravanti Antonella |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (320 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
miR-27a-5p
acute myocardial infarction autophagy apoptosis hypoxia MicroRNA (miRNA) miR526b miR655 oxidative stress reactive oxygen species (ROS) superoxide (SO) Thioredoxin Reductase 1 (TXNRD1) breast cancer nucleic acid medicine pancreatic cancer clinical trial siRNA antisense oligonucleotide MicroRNA signal transduction therapeutic target miRNAs ROS noncoding RNA microRNA long noncoding RNA mitochondrial dysfunction nitrosative stress. exosome cross-talk systemic lupus erythematosus visfatin resistin osteoarthritis synovial fibroblasts synovitis NF-κB thyroid hormone liver cancer metabolism physiology ASH NAFLD NASH HCC HCV HBV endometriosis high-grade serous ovarian cancer endometriosis-associated ovarian cancer epithelial-to-mesenchymal transition chemoresistance antioxidants miRNA cancer diabetes beta cells microRNAs translation regulation neurodegeneration Alzheimer's disease Parkinson's disease Huntington's disease ALS reactive oxygen species redox signaling therapeutic tolerance therapeutic resistance |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557526003321 |
Fioravanti Antonella | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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