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Clostridioides difficile Infection
| Clostridioides difficile Infection |
| Autore | Granata Guido |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (178 p.) |
| Soggetto topico |
Medicine
Epidemiology & medical statistics |
| Soggetto non controllato |
Clostridioides difficile infection
co-morbidities mortality malignancy outcome risk factors C. difficile infection molecular analysis toxin production antibiotic resistance microbiome C. difficile hamsters bovine immunoglobulins 16S rRNA next generation sequencing Clostridioides difficile Charlson comorbidity index Child-Pugh score Clostridioides difficile associated disease CDI nonalcoholic fatty liver disease NAFLD NASH recurrent disease antibacterial Clostridioides (Clostridium) difficile peptidomimetic triazole baicalin gut dysbiosis mouse model spores anti-spore spore germination nanomaterial teicoplanin spore antibiotics multi-step algorithm multiplex "real-time" PCR PCR capillary-based electrophoresis ribotyping Clostridium difficile TcdA TcdB toxin toxemia plasma method quantification CDI severity |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566483503321 |
Granata Guido
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology
| Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology |
| Autore | Fioravanti Antonella |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (320 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
miR-27a-5p
acute myocardial infarction autophagy apoptosis hypoxia MicroRNA (miRNA) miR526b miR655 oxidative stress reactive oxygen species (ROS) superoxide (SO) Thioredoxin Reductase 1 (TXNRD1) breast cancer nucleic acid medicine pancreatic cancer clinical trial siRNA antisense oligonucleotide MicroRNA signal transduction therapeutic target miRNAs ROS noncoding RNA microRNA long noncoding RNA mitochondrial dysfunction nitrosative stress. exosome cross-talk systemic lupus erythematosus visfatin resistin osteoarthritis synovial fibroblasts synovitis NF-κB thyroid hormone liver cancer metabolism physiology ASH NAFLD NASH HCC HCV HBV endometriosis high-grade serous ovarian cancer endometriosis-associated ovarian cancer epithelial-to-mesenchymal transition chemoresistance antioxidants miRNA cancer diabetes beta cells microRNAs translation regulation neurodegeneration Alzheimer's disease Parkinson's disease Huntington's disease ALS reactive oxygen species redox signaling therapeutic tolerance therapeutic resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557526003321 |
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Fioravanti Antonella
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Energy Metabolism and Diet
| Energy Metabolism and Diet |
| Autore | Nieuwenhuizen Arie |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (114 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
insulin
lipogenesis obesity glucose homeostasis adipocytes cortisol ketones s-IgA exercise low carbohydrate diet NAFLD omega-3 krill oil phospholipids high-fat diet C57BL/6N mice thermoneutral temperature iron deficiency striated skeletal muscle physical capacity fatigue mitochondrial metabolism complex I resting metabolic rate prediction equation ageing adults overweight adiposity-based chronic disease energy balance metabolism |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576883203321 |
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Nieuwenhuizen Arie
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Drug Research in China: Selected Papers from the 15-NASMD Conference
| Marine Drug Research in China: Selected Papers from the 15-NASMD Conference |
| Autore | Zhou Xuefeng |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (512 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Antarctic krill (Euphausia superba)
peptide antioxidant activity stability oyster plasma peptidome antimicrobial peptides cytotoxicity actinomycete piericidins absolute configuration Pestalotiopsis heterocornis heterocornols anti-inflammatory activity sponge-derived fungus sclerotides lipodepsipeptide Aspergillus sclerotiorum nasopharyngeal carcinoma AChE inhibitory vascular endothelial cell flavonoid oxidized low-density lipoprotein Nrf2 apoptosis butyrolactone I food allergy metabolism pharmacokinetics actinomycin X2 microbial pigments dyeing silk antibacterial properties PD-L1 virtual screening pharmacophore modeling ADME molecular dynamics xanthones ascidian-derived fungus Diaporthe sp anti-glioma activity antiaging Sonneratia apetala signaling pathway Caenorhabditis elegans mutants coral-derived fungi Aspergillus hiratsukae meroterpenoids antibacterial activity cytotoxic activity deep-sea-derived fungus Aspergillus puniceus isoquinoline alkaloid protein tyrosine phosphatase inhibitor antibacterial Aspergillus sp geodin semisynthesize insecticidal activity Arca inflata antitumor peptide MAPK signaling calmodulin colorectal cancer methicillin-resistant Staphylococcus aureus actinomycin D Streptomyces parvulus mechanism mangrove endophytic Pestalotiopsis Sdy-1 antitumor activity Wnt signaling β-catenin eremophilane sesquiterpenoids mangrove-derived fungus Penicillium sp Oceanapia sponge secondary metabolites biological activities drug design anticancer cyclic pentapeptide galaxamide analogues skipjack tuna (Katsuwonus pelamis) muscle angiotensin-I-converting enzyme (ACE) peptide molecular docking nitric oxide (NO) endothelin-1 (ET-1) Trichoderma longibrachiatum sesquiterpene glycoside antimicrobial activity marine fungi Aspergillus unguis depsides depsidones osteoclast differentiation soft-coral-derived fungus pyranodipyran derivatives tyrosyl DNA phosphodiesterase 1 inhibitory activities fluorescent properties butenolides enantiomers Aspergillus terreus pancreatic lipase NAFLD fucoxanthin adenosine monophosphate-activated protein kinase (AMPK) nuclear factor erythroid-2-related factor 2-mediated (Nrf2) Toll-like receptor 4-mediated (TLR4) Aspergillus flavipes HN4-13 emodin macroporous resin XAD-16 adsorption kinetics and isotherms enrichment tetramic acid derivatives deep-sea fungus clavipitacae Lecanicillium fusisporum chronic kidney disease fucoidan cognitive dysfunction neuroinflammation oxidative stress GSK3β-Nrf2-HO-1 signaling microglial polarization deep-sea actinomycetes aromatic acids oximes antihyperlipidemic phycocyanin microbiota transcriptome IL-17 pathway Hahella prodiginine chejuenlide genome mining LC-MS/MS CDK4/6 marine compounds pharmacophore construction ADMET mm-pbsa |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Marine Drug Research in China |
| Record Nr. | UNINA-9910595071903321 |
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Zhou Xuefeng
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metabolism and Metabolomics of Liver in Health and Disease
| Metabolism and Metabolomics of Liver in Health and Disease |
| Autore | Wahli Walter |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (268 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
nonalcoholic fatty liver disease
nonalcoholic steatohepatitis Fibrosis Liver biopsy Genomics Metabolomics Proteomics Transcriptomics nicotinamide NAFLD steatosis heat stress primary mouse hepatocytes metabolic profile GC-MS multivariate statistical analysis arachidonic acid docosahexaenoic acid inflammation fibrosis lipidomics mass spectrometry in vitro HepaRG sodium saccharin reference toxicants de novo lipogenesis carbohydrate response element-binding protein ChREBP diabetes glucose production glycogen glycolysis glycogen storage disease type I hexosamine pentose phosphate pathway acupuncture imflammation lipid metabolism oxidative stress metabolomics quantitative profiling 1H-NMR spectroscopy liver bile acids metabolomics rat plasma tandem mass spectrometry liquid chromatography acetaminophen hepatotoxicity biomarker premalignant alcoholic liver disease cholestasis cirrhosis NAFL NASH standard operating procedures urine blood feces tissue cells liver function nonalcoholic fatty liver liquid chromatography-mass spectrometry nuclear magnetic resonance spectroscopy metabolic pathway non-alcoholic fatty liver disease non-alcoholic steatohepatitis transcription factors metabolic stress lipid homeostasis glucose homeostasis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557148103321 |
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Wahli Walter
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Lipid Lowering Therapies for Cardiovascular and Metabolic Diseases: Lessons from the Past and Future Challenges
| New Lipid Lowering Therapies for Cardiovascular and Metabolic Diseases: Lessons from the Past and Future Challenges |
| Autore | Bakillah Ahmed |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (116 p.) |
| Soggetto non controllato |
apolipoprotein
lipids risk stratification proprotein convertase subtilisin-kexin type 9 (PCSK9) vaspin sphingolipids PCSK9 ceramides atrial fibrillation circular RNA STEMI cholesterol lipoproteins cardiovascular disease (CVD) coronary artery bypass grafting atherosclerosis statin LDL subfractions acute kidney injury dyslipidemia gene expression NSTEMI NAFLD hyperlipidemia nonstatin cholesteryl ester transfer protein low-density lipoprotein cholesterol anacetrapib HDL acute coronary syndrome miRNA cardiovascular risk pleiotropic actions genetic ABCA1 sdLDL cardiovascular disease proprotein convertase subtilisin/kexin type 9 inclisiran reverse cholesterol transport sterol small interfering RNA (siRNA) RNA-binding proteins cardiovascular diseases NASH low-density lipoprotein-cholesterol (LDL-C) stroke nutrigenetics type 2 diabetes statins sphingomyelin hepatic fibrosis diabetes |
| ISBN | 3-03921-677-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | New Lipid Lowering Therapies for Cardiovascular and Metabolic Diseases |
| Record Nr. | UNINA-9910367751903321 |
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Bakillah Ahmed
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Biomarkers for Heart Disease
| Novel Biomarkers for Heart Disease |
| Autore | Lichtenauer Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (420 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
diet quality
ceramides obesity cardiovascular risk healthy eating index carbohydrate antigen-125 heart failure inflammatory marker older women biomarker cardiometabolic disease epicardial adipose tissue epicardial fat epicardial fat volume microRNA thyroid-stimulating hormone cardiometabolic risks metabolic syndrome hypertension very low-density lipoprotein STIM1 SOCE atrial myopathy atrial fibrillation ejection fraction soluble urokinase-type plasminogen activator receptor (suPAR) growth differentiation factor 15 (GDF-15) heart-type fatty acid-binding protein (H-FABP) soluble suppression of tumorigenicity 2 (sST2) acute myocardial infarction biomarkers catestatin coronary artery disease heart failure decompensation left ventricular ejection fraction troponin NT-proBNP NYHA functional class GDF-15 cardiovascular surgery operative risk muscle wasting sarcopenia renal dysfunction chronic kidney disease aortic disease aneurysm miRNA TGF-β pathway KLF4 synthetic phenotype aortic regurgitation echocardiography magnetic resonance imaging vena contracta area longitudinal strain T1 mapping GDF8 myostatin AMI ceruloplasmin H-FABP heart-type fatty acid-binding protein FABP3 fatty acid-binding protein 3 HF cardiac biomarkers cardiac magnetic resonance imaging left ventricular systolic function magnetic resonance spectroscopy myocardial triglyceride content cell adhesion molecule repeated measurements pregnancy-associated plasma protein-A cohort studies cardiovascular diseases mitochondrial dysfunction circulating cells PBMCS platelets oxidative stress reactive oxygen species (ROS) mitochondrial DNA (mtDNA) herat failure liver-type fatty-acid-binding protein long-term outcomes cardiac intensive care units acute kidney injury myocardial infarction STEMI cardiovascular events cardiovascular death risk stratification sST2 Pentraxin-3 sudden cardiac death ventricular arrhythmia ventricular tachycardia chronic heart failure saliva salivary biomarkers CKD CVD PPCI left ventricular adverse remodelling circulating miRNAs NAFLD Framingham risk score risk prediction secondary prevention primary prevention NAFLD fibrosis score HFpEF HFrEF suPAR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557546203321 |
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Lichtenauer Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Natural Products for Human Health
| Plant Natural Products for Human Health |
| Autore | Zhang Hongjie |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (514 p.) |
| Soggetto non controllato |
PhGs
bitter orange immunomodulator A549 cells bergapten triptolide BMP/Smad phytochemicals antioxidant enzymes kumquat MTT assay HepaRG cells human health nanoparticles dendritic cells drug discovery biofilm catechin antitubercular activity Panax notoginseng saponins animals mouse-hair growth A? curcumin WNT/?-catenin copaiba AD Plasmodium parasites traditional medicine procyanidin A2 PET inhibition rheumatoid arthritis cannabinoid type 1 receptor iridoids inflammatory bowel disease acute liver injury human-hair-follicle dermal papilla cells Neuroprotective dihydromyricetin AMPK thromboembolism ginseng drug design and development endoplasmic reticulum stress mitogen-activated protein kinase Nrf2 prenylated flavonoids inflammation preclinical studies plants dietary supplements Glycyrrhiza uralensis aspirin Tripterygium wilfordii P. eryngii reperfusion ethnopharmacology glucans innovation hpatoprotection hinokitiol phytocannabinoid antistaphylococcal activity Shh/Gli green tea sesquiterpenoids adjuvant-induced arthritis yuzu hepatotoxicity p53/Bax Keap1 nuclear factor-kappaB oxidative stress pharmacokinetic study cinnamamides toxicity APAP Astragali Radix computational softwares plant natural product onion anti-malaria activity lipogenesis bleeding time diterpenoids Penthorum chinense Pursh myocardial hypertrophy automation adjuvant grapefruit melanoma cell essential oil sweet orange Amadori rearrangement compounds heme oxygenase global health calorie restriction bergamot liposomes EGCG celastrol herb–drug interactions cannabigerol anti-inflammation OH· free radical molecular targets gluconeogenesis microbiome SIRT1 fucoidan heart PC12 cells acetaminophen omics time-kill assay arthritis lychee seed bioinformatics structure–activity relationship precision medicine orange petitgrain immune modulation antiproliferation flavonoids scoulerine oleoresin triterpenic acids Cannabis sativa NAFLD biological activity differentiation oxygen consumption rate mitochondrial bioenergetics neroli apoptosis targeted delivery platelet activation protein kinase heat-process hepatic steatosis hyperglycemia natural products lemon genistein neuroinflammation astragaloside IV cytoxicity flavonoid paracetamol medicinal plants insulin resistance resveratrol mandarin garlic TGF-? morin hydrate sirtuin 3 MMPs gomisin N lime Ziziphus jujuba antifungal activity ischemia migration caspases small molecules |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346688103321 |
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Zhang Hongjie
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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With Obesity Becoming the New Normal, What Should We Do?
| With Obesity Becoming the New Normal, What Should We Do? |
| Autore | Samaras Katherine |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (167 p.) |
| Soggetto topico |
Medicine
Endocrinology |
| Soggetto non controllato |
obesity
childhood obesity body mass index fat epidemic weight loss NAFLD diabetes heart polycystic ovary syndrome |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557239403321 |
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Samaras Katherine
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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