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Mitochondria-targeted drug delivery
| Mitochondria-targeted drug delivery |
| Autore | Kopecka Joanna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (290 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
retinal ischemia
blood-brain barrier endothelial reactive oxygen species oxidative stress tunneling nanotubules neuron central nervous system inflammation hypoxia anticancer peptide (ACP) antimicrobial peptide (AMP) anticancer peptides antimicrobial peptides host defense peptides prediction random forest mitochondria mitochondrial DNA mitochondrial disorders pharmacological therapy gene therapy precision medicine cardiovascular disease drug delivery mitochondria dysfunctions nanocarriers oxoglutarate carrier malate-aspartate shuttle cancer metabolism ATP production diphenyleneiodonium NADPH-oxidase differentiation proliferation mitochondria-targeted antioxidants LPS mitochondrial ROS antitumor agents fluorescence lifetime imaging medicinal chemistry metabolic drug mitochondrial carrier melanoma plumbagin cytotoxic effect metabolism cholesterol lipid raft mitochondrial permeability transition pore alkylphospholipid analog edelfosine mitochondrial oncometabolites cancer drug resistance mitochondrial disease heteroplasmy mitochondrial gene delivery |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576881503321 |
Kopecka Joanna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Roles and Functions of ROS and RNS in Cellular Physiology and Pathology
| Roles and Functions of ROS and RNS in Cellular Physiology and Pathology |
| Autore | Zarkovic Neven |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto non controllato |
toxicity
toll-like receptors acrolein hydroxyapatite-based biomaterials LC-MS/MS blood–brain barrier NADPH-oxidase human neuroblastoma SH-SY5Y cells NRF2-NQO1 axis granulocytes free radicals antioxidant plaque vulnerability bEnd.3 relaxation Ca2+ keratinocytes oxidative metabolism of the cells lipid peroxidation intermittent hypoxia osteoblast growth UV radiation ROS bEnd5 cyclopurines NF?B glucose deprivation antimicrobial endothelial cells 4-hydroxynonenal (4-HNE) histamine glutamine deprivation optical coherence tomography antioxidants DNA damage glutathione NQO1 transcript variants xeroderma pigmentosum cancer cells VAS2870 reactive oxygen species (ROS) TP53 mutation DNA and RNA polymerases viability oxidative burst macrophages inflammation Nrf2 von Willebrand factor reactive oxygen species growth control intracellular signaling MFN2 nuclear factor erythroid 2–related factor 2 fusion/fission IMR-90 calcium proliferation mitochondria pathophysiology of oxidative stress redox balance 4-hydroxynonenal cannabidiol oxidative homeostasis rs1800566 neuronal cell death heme-oxygenase-1 vitamins cell signaling TRPM2 channel aorta cancer growth cancer regression oxidative stress nucleotide excision repair |
| ISBN | 3-03928-783-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087603321 |
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Zarkovic Neven
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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