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Challenges and Advances in Tuberculosis and Mycobacterial Lung Diseases
| Challenges and Advances in Tuberculosis and Mycobacterial Lung Diseases |
| Autore | Szturmowicz Monika |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (140 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
Gordonia bronchialis
microbiological diagnostics respiratory infection Mycobacterium tuberculosis drug resistance XDR-tuberculosis household TB transmission tuberculous pericarditis extrapulmonary tuberculosis pericarditis constrictive pericarditis tuberculosis abscess scrofula head and neck epiglottis larynx airway mycobacteria surgical drainage FluoroType MTBDR molecular isoniazid rifampin bacillus Calmette-Guerin bladder cancer immunotherapy BCGosis BCG pulmonary infection severe respiratory insufficiency nontuberculous mycobacterium lung cancer surgery nontuberculous mycobacteria cystic fibrosis chest computed tomography Beijing-TB Beijing-like genotype Mycobacterium chimaera nontuberculous mycobacterial disease silicosis extracorporeal membrane oxygenation COVID-19 pandemic spoligotyping Poland human immunodeficiency virus acquired immunodeficiency syndrome chest imaging rapidly growing mycobacteria antimicrobial resistance broth microdilution minimal inhibitory concentration (MIC) |
| ISBN | 3-0365-5492-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637783103321 |
Szturmowicz Monika
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
| Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics |
| Autore | Tutone Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (387 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
3CL-Pro
3D-QSAR acetylcholinesterase aging progression mechanism Alzheimer's disease aminophenylbenzamide antibody:antigen interactions antivirals binding free energies binding site binding space carbon nanotubes cholesterol computational biology consensus models COVID-19 COX-2 inhibitors deep learning diabetes docking simulations doxorubicin encapsulation drug delivery system drug discovery drug repositioning drug repositioning approaches drug repurposing drug resistance drug-resistance mutations dual mode of action dual-target lead discovery epitope binning epitope mapping epitope prediction FimH fingerprints gene expression signature genome-wide genetic and epigenetic network (GWGEN) glycoprotein D (gD) haeckelite defects HDACs hERG toxicity herpes simplex virus fusion proteins high-throughput virtual screening HIV-2 protease homology modeling hTSPO human dihydrofolate reductase immunoproteasome in silico induced structural deformations induced-fit docking inhibitors isoform-selective histone deacetylase inhibitors isomeric space ligand-based model machine learning main protease MD binding MD simulation metadynamics methotrexate molecular docking molecular dynamics molecular dynamics (MD) simulation molecular dynamics simulation molecular dynamics simulations molecular modeling MRP4 multi-modal multiple-molecule drug multiprotein inhibiting natural compounds multiscale multitargeting mutants Mycobacterium tuberculosis n/a natural compounds neurodegenerative disorders nicotinic acetylcholine receptor non-covalent inhibitors noncovalent interactions oxidative stress PF-00835231 pharmacophore model pharmacophore modeling PK11195 polypharmacology proteasome protein docking protein threading modeling proteomic signature RNA expression regulation SARS-CoV-2 skin aging SNPs sodium-glucose co-transporters 2 Src inhibitors Stone-Wales defects structural bioinformatics structural characterization systems medicine design tuberculosis urinary tract infections uropathogenic bacteria variants virtual screening |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Computational Approaches |
| Record Nr. | UNINA-9910557519403321 |
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Tutone Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0
| Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0 |
| Autore | Dansette Patrick M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (286 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
20-HETE
active site access channels Antibiotics arachidonic acid azole drugs Bacillus Bietti's crystalline dystrophy biosynthetic gene clusters cavities boundaries circulatory CYPs comparative analysis cryptococcus cryptococcus neoformans crystal structure Cyanobacteria CYP diversity analysis CYP128A1 CYP139A1 CYP2C8 CYP3A4 CYP4 genes CYP450 CYP51 Cytochrome b5 (CYB5) cytochrome P450 cytochrome P450 monooxygenase cytochrome P450 monooxygenases cytochrome P450 monooxygenenases cytochrome P450 reductase cytochromes P450 cytochromes P450 monooxygenases drug metabolism electron transfer electron-transfer (ET) enzyme substrate specificity exosomes extracellular vesicles extrahepatic tissues fatty acid fungal pathogens gene-cluster diversity percentage genetic polymorphisms genome data mining genome data-mining host metabolism human pathogens isoform lamellar ichthyosis mathematical formula mechanism-based inhibitor membrane protein menaquinone metabolism microsomal cytochrome P450 (CYP) minimal cost paths molecular dynamic simulations molecular dynamics simulation molecular functionality mutagenesis Mycobacterium Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv NADPH-cytochrome P450 reductase (CPR) non-ribosomal peptides P450 blooming P450 diversity percentage P450 profiling paclitaxel phylogenetic analysis plasma polyketides polymorphisms precision Cardio-Oncology precision medicine protein dynamics protein-membrane interactions protein-protein interaction reactive oxygen species RNA interference secondary metabolites SNPs Sogatella furcifera Streptomyces sulfoxaflor systems medicine terpenes transcriptome tremellomycetes trichosporon tuberculosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cytochromes P450 |
| Record Nr. | UNINA-9910557761103321 |
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Dansette Patrick M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Five Years of Separations : Feature Paper 2018
| Five Years of Separations : Feature Paper 2018 |
| Autore | Samanidou Victoria |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (152 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
alkylated polycyclic aromatic hydrocarbons (alkylated PAHs)
antibody-drug conjugate biological fluids biopharmaceutical bisphosphonates capillary liquid chromatography chromatographic selectivity cosmetic analysis cytotoxicity diacyltrehalose diphenylamine dissolution dry cotton swab fragrance allergens gas chromatography gas chromatography-mass spectrometry GC-MS/MS glycolipid gunshot residues hands hydrophobicity in-tube solid-phase extraction ionic liquid stationary phase linear ion trap liquid chromatography-mass spectrometry matrix solid-phase dispersion membrane filtration-treatment membrane fouling mechanism membrane type-operation micellar electrokinetic chromatography miniaturized extraction technique Mycobacterium tuberculosis PDA personal care products plasticizers polycyclic aromatic hydrocarbons preservatives quantitation recycled diatomaceous earth risedronate sample treatment SEM-EDX solid phase microextraction synthetic musks tablets tandem mass spectrometry tannery industrial wastewater thyroid tiludronate tricyclic antidepressants (TCAs) UV filters vibratory shear-enhanced process (VSEP) ZIC-HILIC zoledronate μ-MSPD |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Five Years of Separations |
| Record Nr. | UNINA-9910557299503321 |
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Samanidou Victoria
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Host-Directed Therapies for Tuberculosis
| Host-Directed Therapies for Tuberculosis |
| Autore | Venketaraman Vishwanath |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (120 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
antioxidants
antiplatelet aspirin autophagy BCG vaccination co-infections co-morbidities cytokines gene expression glutathione granulomas host-directed therapies immune exhaustion immune response immune responses immunomodulation inflammation invasive procedure iron supplementation latent infection lung cancer M. tb misdiagnosis Mycobacterium tuberculosis pathology Perls' stain pulmonary rabbit redox imbalance revising survival Taiwan tuberculosis type 2 diabetes |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557602603321 |
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Venketaraman Vishwanath
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Microbial modulation of host apoptosis and pyroptosis / / topic editors: Yongqun He and Amal O. Amer
| Microbial modulation of host apoptosis and pyroptosis / / topic editors: Yongqun He and Amal O. Amer |
| Autore | Amal O. Amer |
| Pubbl/distr/stampa | Frontiers Media SA, 2014 |
| Descrizione fisica | 1 online resource (109 pages) : illustrations; digital, PDF file(s) |
| Collana | Frontiers Research Topics |
| Soggetto topico |
Cytology
Biology Health & Biological Sciences |
| Soggetto non controllato |
microbial infection
pyroptosis Mycobacterium tuberculosis bacterial exploitation of apoptosis Brucella Infectious Disease Inflammasome Legionella programmed cell death Apoptosis |
| ISBN | 9782889192809 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137207203321 |
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Amal O. Amer
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| Frontiers Media SA, 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment
| Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment |
| Autore | Ferraris Davide Maria |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (128 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
antitubercular drug discovery
antitubercular treatments apoptosis Beijing B0/W148 Beijing genotype BM-MSCs bone-homing CD38 Central Asia Outbreak cytokine drug discovery drug resistance drug target effector efflux gene expression HLA-DR host-pathogen interactions IL-18 IL-18BP IL-18R imidazo[1,2-b][1,2,4,5]tetrazine immune activation immune response latent tuberculosis line probe assay liposomes M. tuberculosis macrophage MDR-TB microRNA MmpS5-MmpL5 Mtb murine infection model Mycobacterium Mycobacterium avium Mycobacterium smegmatis Mycobacterium tuberculosis omics analysis pre-XDR-TB relapse second-line drugs stem cell niche subtractive genomics system analysis TB treatment treatment response tuberculosis uncharacterized proteins unique metabolic pathways Virulence XDR-TB |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557291103321 |
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Ferraris Davide Maria
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Perfil epidemiológico y terapéutico de pacientes con tuberculosis pulmonar en la ciudad de Cali, Colombia
| Perfil epidemiológico y terapéutico de pacientes con tuberculosis pulmonar en la ciudad de Cali, Colombia |
| Autore | Cabrera Tello Mónica |
| Pubbl/distr/stampa | Colombia, : Universidad Santiago de Cali, 2018 |
| Descrizione fisica | 1 online resource (45-61 p.) |
| Disciplina | 616.014 |
| Soggetto topico | Biochemistry |
| Soggetto non controllato |
Antibióticos
Bacterias Mycobacterium tuberculosis Patógenos Salmonella entérica Salud Staphylococcus aureus |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | spa |
| Record Nr. | UNINA-9910571779203321 |
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Cabrera Tello Mónica
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| Colombia, : Universidad Santiago de Cali, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Protein-Ligand Interactions: Target Identification and Drug Discovery
| Protein-Ligand Interactions: Target Identification and Drug Discovery |
| Autore | Altieri Fabio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (184 p.) |
| Soggetto topico |
Chemistry
Research and information: general |
| Soggetto non controllato |
ACE
acetylcholinesterase amyloid beta aggregation brassicasterol cancer cell death cell viability CoCl2 drug development drug discovery endocrine disruptor compound fatty acid conjugation FcRn-mediated recycling fluorescence spectroscopy GADD45β heat shock protein 70 Hsp70 HSV HSV-1 DNA polymerase HSV-1 TK human CDK2 human umbilical artery kinase regulation lipid signalling lipid-protein interaction lung cancer cell line membrane mitochondrial membrane potential MKK7 molecular biophysics molecular docking molecular docking simulation molecular dynamics multi-target drug multiple myeloma Mycobacterium tuberculosis NCI60 COMPARE analysis neuroprotection PGRMC1 phosphatidylinositols phytosterols piperine protein-ligand interaction reactive oxygen species (ROS) serum albumin serum half-life extension sigma ligands sigma receptors SIGMAR1 small-molecule derivatives of salicylanilide STD-NMR structure-activity relationship target identification thyroid diseases TMEM97 translocator protein (TSPO) UDP-galactopyranose mutase vascular homeostasis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Protein—Ligand Interactions
Protein-Ligand Interactions Protein–Ligand Interactions |
| Record Nr. | UNINA-9910557497703321 |
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Altieri Fabio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tuberculosis Drug Discovery and Development 2019
| Tuberculosis Drug Discovery and Development 2019 |
| Autore | Riccardi Giovanna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (296 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
anti-TB drug pipeline
anti-virulence compounds antibiotic antimicrobial drug resistance (AMR) antimycobacterial antituberculosis agents artificial pneumothorax BCG bedaquiline biomarkers Carlo Forlanini caseum cell envelope clinical studies clinical trial CTVD delpazolid discovery DNA gyrase dormancy DprE1 inhibitor drug combination drug development drug discovery drug resistance drug-drug interactions EDCTP electron transport chain energy metabolism genomics granulomas host-directed therapy IAVI in vitro in vivo isoniazid lead generation lipidomics macozinone mechanism of action mechanisms of resistance metabolomics MID3 mode of action multi-drug resistance mutations mycobacteria mycobacterium Mycobacterium tuberculosis n/a oxidative phosphorylation pharmacodynamics pharmacokinetics phenotypic screening PknB PknG post-treatment sequelae privileged targets promiscuous targets proteomics pulmonary rehabilitation Q203 rifampin structure-based drug design surgery target target identification target-based drug design target-based screening TB TBVI toxicity transcriptomics tuberculosis tuberculosis treatment tuberculosis vaccines |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557627203321 |
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Riccardi Giovanna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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