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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological and Pharmacological Activity of Plant Natural Compounds II
| Biological and Pharmacological Activity of Plant Natural Compounds II |
| Autore | Pezzani Raffaele |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (338 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
Bergenia species
botanical description traditional uses phytochemistry pharmacology anti-urolithiatic activity bergenin Flaxseed oil linusorb B3 anti-cancer apoptosis actin polymerization Src glioblastoma chlorogenic acid coffee cyclooxygenase espresso instant coffee platelet aggregation Rubia tinctorum L. antioxidants polyphenols ethylene glycol urolithiasis histophatology Saccharomyces cerevisiae β-glucan antimicrobial and anticancer activities detoxification ability immunomodulatory effect Aquilaria sinensis pheophorbide A MMP-2 MMP-9 HT-1080 advanced glycation end product (AGE) oxidative stress epithelial to mesenchymal transition AGE-inhibitor swertiamarin diabetic nephropathy astragaloside IV Astragalus membranaceus huang qi Astragali Radix liver liver regeneration 70% partial hepatectomy proliferation rat memory object recognition Ginkgo biloba dorsal hippocampus formation brain-derived neurotrophic factor Diclofenac γ-lactone nano-emulsion methylcellulose Ostrich oil Struthio camelus Caenorhabditis elegans leaf extract neuroprotection antioxidant activity DAF-16 Clerodendrum infortunatum terpenoids phenylpropanoids antidiabetic breast cancer Combretum indicum L. antidiabetic activity histopathology UPLC-QTOF/ESI-MS network pharmacology Biebersteinia heterostemon galegine hypotensive toxicity Sage Salvia officinalis cytotoxicity hepatoprotection MDA TAOxC MCF-7 HeLA cells HepG-2 cells Peganum harmala anti-inflammatory activity antioxidant LC-ESI-MS/MS traditional medicine rheumatoid arthritis rosmanol carnosol Callicarpa longissima TLR4/NF-κB/MAPK synergistic effect diabetes mellitus anti-diabetic drugs monoterpenes |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566486603321 |
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Pezzani Raffaele
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Carbon Nanomaterials for Therapy, Diagnosis, and Biosensing
| Carbon Nanomaterials for Therapy, Diagnosis, and Biosensing |
| Autore | Mazzaglia Antonino |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (166 p.) |
| Soggetto topico |
Technology: general issues
Chemical engineering |
| Soggetto non controllato |
graphene oxide
covalent functionalization cortical membranes calcium phosphate deposition graphene/gold nanocomposite SERS Dopamine Rhodamine 6G nanodiamond tritium biodistribution Ewing sarcoma drug delivery siRNA nanomedicine porphyrin J-aggregates carbon nanotubes nanohybrids graphene liquid biopsy circulating tumor cells exosomes circulating nucleic acids COVID-19 pyrrole cancer doxorubicin drug delivery systems nanoparticles carbon dots platelet aggregation arterial thrombosis signaling molecules bleeding disorder cytotoxicity carbon nanomaterials camptothecin Caco-2 MCF-7 NanoHy-GPS antibacterial nanosystems one-pot microwave-assisted reaction silver nanoparticles polyvinyl alcohol |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580204103321 |
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Mazzaglia Antonino
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthesis of Flavonoids or Other Nature-Inspired Small Molecules
| Synthesis of Flavonoids or Other Nature-Inspired Small Molecules |
| Autore | Ribaudo Giovanni |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (82 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
quercetin
flavonoids semi-synthetic PDE sildenafil molecular modeling Garcinia porrecta Clusiaceae xanthone Lansium domesticum Meliaceae MCF-7 triterpene onoceranoid hydrazone (+)-camphor valproic acid technology terpenoid anticonvulsant activity 1,2,3-triazole anticancer aminoquinoline hybrid compound kokosanolide tetranortriterpenoid C. dichotoma antidiabetic α-glucosidase α-amylase docking ADMET curcumin analog organic synthesis photophysical properties steady-state fluorescence DFT calculation 7-hydroxy-2H-chromen-2-one O-acylation reaction coumarin lupeol derivative benzylidene derivative α-glucosidase inhibition Oxone® |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557615703321 |
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Ribaudo Giovanni
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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