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Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function
| Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function |
| Autore | Pulido Rafael |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (240 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
asthma
astrocytes atypical dual-specificity phosphatases atypical DUSP BDNF brain metastasis cancer cannabinoids circulating tumor cells (CTCs) COPD Cpp1 cytokines DEPArray differentiation dual-specificity phosphatase dual-specificity phosphatases DUSP-4 DUSP10 E. coli infection fungal MKPs granule neurons HDAC6 (histone deacetylase isoform 6) hematopoietic cells HER2 hypertriglyceridemia inflammation influenza integrated omics analysis liver steatosis macrophage macrophages MAP Kinase Phosphatase-2 MAP kinase phosphatases MAP kinases MAPK MAPK phosphatase MAPKs microtubules mitogen-activated protein kinase MK-STYX (MAPK (mitogen-activated protein kinase) phosphoserine/threonine/tyrosine-binding protein) Mkp-1 Msg5 n/a neuroblastoma neuronal differentiation nucleotide receptors P2X7 P2Y13 Pmp1 post-translational modification proliferation protein stability pseudophosphatase respiratory viruses rhinovirus RSV Sdp1 sepsis signaling single cell analysis T cell TLR signaling triple-negative breast cancer (TNBC) ubiquitination |
| ISBN | 3-03921-689-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Dual Specificity Phosphatases |
| Record Nr. | UNINA-9910367740903321 |
Pulido Rafael
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Matrix Metalloproteinases in Health and Disease
| Matrix Metalloproteinases in Health and Disease |
| Autore | Serra Raffaele |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (196 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
acute kidney injury
adhesion apoptosis arterial aneurysms autoantibodies biomarkers Caco-2 CD147 cGMP chronic kidney disease CKD collagenases Crohn's disease dental caries dialysis disease eGFR eNOS fibrosis genetic association health high-flux dialysis hypersensitivity pneumonitis inflammation inflammatory bowel disease iNOS integrin αMβ2 ischemia/reperfusion kidney transplantation leukocytes Mac-1 MAPKs matrix metalloproteinase matrix metalloproteinase-7 matrix metalloproteinase-9 matrix metalloproteinases metalloproteinases MMP-9 MMP1 MMP2 MMPs mouth NGAL NO on-line hemodiafiltration PAD patients periodontitis peripheral vascular disease platelets proteinuria RECK renal replacement therapy SNPs statins synthetic inhibitors TIMP TIMPs |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557409503321 |
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Serra Raffaele
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxicological Effects of Mycotoxins on Target Cells
| Toxicological Effects of Mycotoxins on Target Cells |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (218 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
3-acetyldeoxynivalenol
acetyltransferase acute toxicity Alternaria apoptosis Aspergillus autophagy beauvericin binding protein biosynthetic pathway Bm12 cell BmTudor-sn Bombyx mori cell apoptosis cell culture cell cycle cell protection cells chicken Chou-Talalay method co-culture models combination index combined toxicity cytotoxicity deacetylase deoxynivalenol Destruxin A differentiated Caco-2 cells emerging mycotoxin endophyte fungi Fusarium genotoxicity hepatocyte HepG2 cells HT-2 toxin human Stem Cells in silico prediction in vitro inflammation IPEC-J2 IPEC-J2 cells isobologram isotrichodermin isotrichodermol Loewe additivity lolitrems MAPKs MixLow mixtures mycotoxin interaction mycotoxins n/a neurotoxin occurrence data ochratoxin A Ochratoxin A (OTA) Penicillium RNA-seq silibinin T-2 toxin transcriptome analysis trichothecene |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557291503321 |
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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