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Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment
| Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment |
| Autore | Ferraris Davide Maria |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (128 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Mycobacterium tuberculosis
line probe assay second-line drugs drug resistance XDR-TB MDR-TB omics analysis TB treatment system analysis Beijing B0/W148 Mycobacterium smegmatis imidazo[1,2-b][1,2,4,5]tetrazine MmpS5-MmpL5 efflux drug discovery tuberculosis immune activation HLA-DR CD38 treatment response Mycobacterium macrophage apoptosis effector cytokine microRNA Beijing genotype Central Asia Outbreak murine infection model Virulence pre-XDR-TB Mycobacterium avium unique metabolic pathways subtractive genomics drug target uncharacterized proteins BM-MSCs Mtb bone-homing stem cell niche latent tuberculosis relapse liposomes M. tuberculosis host-pathogen interactions immune response antitubercular drug discovery antitubercular treatments IL-18 IL-18BP IL-18R gene expression |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557291103321 |
Ferraris Davide Maria
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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PPARs as Key Mediators of Metabolic and Inflammatory Regulation
| PPARs as Key Mediators of Metabolic and Inflammatory Regulation |
| Autore | Vázquez-Carrera Manuel |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (456 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
nuclear receptor
gene transcription inflammation molecular docking PPARβ/δ lung pulmonary artery GW0742 GSK3787 docking lipopolysaccharide (LPS) PPARγ ligand coumarin fluorescent ligand screening crystal structure PPAR atopic dermatitis psoriasis metabolic reprograming glucose fatty acids mycobacteria M. tuberculosis M. leprae PPARs lipid droplets metabolic alterations hepatic damage nuclear factors pharmacological targets AMPK GDF15 insulin resistance type 2 diabetes mellitus peroxisome proliferator-activated receptor gamma (PPARγ) real-time PCR ELISA immunohistochemistry signaling pathway PPAR gamma brain neural stem cells infection neuroinflammation HIV Zika cytomegalovirus neurogenesis microglia liver damage toll-like receptor 4 P2Y2 receptor metabolic syndrome resveratrol quercetin PPARα peroxisome β-oxidation PPRE ligand coregulator micronutrients PPARα knockout adipose tissue browning lipid metabolism depression PPARg neuropathology corticotropin releasing hormone norepinephrine subgenual prefrontal cortex amygdala nucleus accumbens common carotid artery occlusion electroretinography fibroblast growth factor 21 pemafibrate peroxisome proliferator-activated receptor alpha retinal ischemia skeletal muscle substrate metabolism nonalcoholic fatty liver disease (NAFLD) sex dimorphism lipidomics hepatic sex-biased gene expression PPARγ pulmonary arterial hypertension TGFβ vascular injury proliferation kidney fibrosis pattern-recognition receptors phagocytosis nitric oxide synthase fenofibrate oleoylethanolamide palmitoylethanolamide cancer immunity obesity diabetes miRNA DNA methylation histone modification peroxisome-proliferator-activated receptor fatty acid oxidation doping control regulatory T cells exercise nuclear receptors nutrigenomics energy homeostasis dairy animals non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) peroxisome proliferator-activated receptors (PPAR) bezafibrate fenofibric acid peroxisome proliferator-activated receptor dual/pan agonist X-ray crystallography |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576873703321 |
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Vázquez-Carrera Manuel
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxin-Antitoxin Systems in Pathogenic Bacteria
| Toxin-Antitoxin Systems in Pathogenic Bacteria |
| Autore | Alonso Juan Carlos |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tuberculosis
toxin-antitoxin systems bacterial cell death NAD+ stress-response toxin-antitoxin system mazF type II toxin mRNA interferase X-ray crystallography cognate interactions cross-interactions molecular insulation antitoxin TA systems addiction anti-addiction type I toxin-antitoxin system small protein toxin structure Fst/Ldr family toxin-antitoxin M. tuberculosis bacteria pathogenesis protein-protein interactions cross-talk protein interface tolerance persistence cross-resistance PemI/PemK Klebsiella pneumoniae toxin activation antibacterial agents bacterial persistence Stenotrophomonas maltophilia opportunistic pathogen clinical origin environmental origin biofilm antibiotic resistance cell wall inhibition nucleotide hydrolysis uridine diphosphate-N-acetylglucosamine |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674020103321 |
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Alonso Juan Carlos
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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