Antitumoral Properties of Natural Products |
Autore | Fabiani Roberto |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (344 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557419703321 |
Fabiani Roberto | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Antitumoral Properties of Natural Products : Volume 2 |
Autore | Fabiani Roberto |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (300 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Antitumoral Properties of Natural Products |
Record Nr. | UNINA-9910557531303321 |
Fabiani Roberto | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Autophagy in Tissue Injury and Homeostasis |
Autore | Lin Pei-Hui |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (322 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
aging
dietary restriction acute kidney injury mitochondria autophagy mitophagy ischemia renal tubular cells diabetic nephropathy exosomes mTOR innate immunity immune cell inflammasome Paneth cell inflammatory bowel disease Crohn's disease hepatocytes hepatic stellate cells sinusoidal endothelial cells macrophages fibrosis cirrhosis hepatocellular carcinoma biomarkers cell death glutaminase metabolism molecular rehabilitation kidney diseases oxidative stress inflammation ATGs intestinal homeostasis inflammatory bowel diseases HCC therapy Autophagy acute lung injury idiopathic pulmonary fibrosis COPD tuberculosis PAH cystic fibrosis Beclin-1 cardiac dysfunction sepsis endotoxemia muscle regeneration stem cell immune macrophage senescence exercise caloric restriction diabetic retinopathy PINK1 Notoginsenoside R1 ethanol LC3 apoptosis Sertoli cell Parkin TFEB infertility AMPK FOXO MTOR parkin spinal cord injury traumatic brain injury autophagic flux neuronal cell death lysosomal damage |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557284203321 |
Lin Pei-Hui | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Bioactive Phytochemicals in Health and Disease |
Autore | Iriti Marcello |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (264 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
quercetin
nervous system molecular signals pharmacological potential cognitive impairment micronuclei radioprotectors radiation effects melanoma PNT2 B16F10 cells Ulmus parvifolia wound healing matrix metalloproteinase transforming growth factor skin rejuvenation kaempferol naringin orientin rutin vitexin chlorogenic acid citric acid malic acid quinic acid rosmarinic acid curcumin nanocurcumin neurological disorders nanocarriers liposomes cancer diet flavonoids food supplements hormesis phytoestrogens sulforaphane resveratrol cardiovascular disease nanomedicine liposome nanoformulation RNA-dependent RNA polymerase remdesivir chloroquine SARS-CoV-2 COVID-19 spike glycoproteins Acorus calamus ethnomedicinal phytochemistry toxicity pharmacological action clinical trial neuroprotective neurological metabolic application kurarinone coronavirus HCoV-OC43 autophagy infection MRC-5 cell LC3 p62/SQSTM1 protein |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557389003321 |
Iriti Marcello | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Ubiquitin and Autophagy |
Autore | Nazarko Taras Y |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (294 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
PSMD14
ubiquitin retrograde trafficking APP autophagy Cx43 GABARAP gap junction MAPLC3 leukodystrophies globoid cell leukodystrophy psychosine p62 proteasome toll-like receptor 4 TRAF6 BECN1 ATG12~5/16 complex Dictyostelium ubiquitin-like protein phagocytosis pinocytosis UPS ubiquitin-proteasome system crosstalk tissue specificity C. elegans NFAT5 autophagy initiation islet FIP200 unfolded protein response UPR Atg8 LC3 LIR motif SAR UBL neurodegenerative diseases autophagy-lysosome pathway lysosome selective autophagy ubiquitination degradation the ubiquitin-proteasome system plants mitophagy aggrephagy lysophagy xenophagy lipophagy nucleophagy ER-phagy cargo receptors sorting nexins retromer endosome |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557339503321 |
Nazarko Taras Y | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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