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Advances in Mechanisms of Renal Fibrosis
| Advances in Mechanisms of Renal Fibrosis |
| Autore | David J. Nikolic-Paterson |
| Pubbl/distr/stampa | Frontiers Media SA, 2018 |
| Descrizione fisica | 1 electronic resource (84 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
TGF-beta
fibroblast JNK miRNA Smad non-classical RAS BMP7 HDAC HIPK2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346754103321 |
David J. Nikolic-Paterson
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| Frontiers Media SA, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anti-aging Nutrients with Health Beneficial Effects
| Anti-aging Nutrients with Health Beneficial Effects |
| Autore | Katakura Yoshinori |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
raw-milk cheese
Caenorhabditis elegans longevity oxidative stress DAF-16 p38 MAPK anthocyanins structure glucose and lipid metabolism human health meta-analysis telomerase reverse transcriptase keratinocyte–hair follicle stem cell interaction exosomes telogen–anagen transition hair cycle regulation caffeine intestinal aging anti-aging vitellogenesis mitochondrial function oxidative stress response GABA exosome gut-brain interaction Caco-2 SH-SY5Y argan press-cake MITF JNK cAMP/PKA Wnt/β-catenin microarray analysis maslinic acid muscle atrophy muscle strength denervation olive peel SGLT1 transporter tangeretin cardamonin intestinal epithelial cell Phgdh liver l-serine deficiency insulin signaling glucose tolerance inflammaging aging related disorders low grade inflammation nutrients natural herbs pro-inflammatory cytokines regulatory T cells retinaldehyde dehydrogenase IgA quercetin luteolin |
| ISBN | 3-0365-5070-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619467703321 |
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Katakura Yoshinori
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products
| Antitumoral Properties of Natural Products |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (344 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557419703321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products : Volume 2
| Antitumoral Properties of Natural Products : Volume 2 |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antitumoral Properties of Natural Products |
| Record Nr. | UNINA-9910557531303321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria in Health and Diseases
| Mitochondria in Health and Diseases |
| Autore | Javadov Sabzali |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (434 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
hypoglycemia
sodium dichloroacetate pyruvate dehydrogenase kinase pyruvate dehydrogenase oxidative stress neuron death cholangiocellular carcinoma mitochondria energy metabolism oxidative phosphorylation 4-HNE DRP1 ERK1/2 hippocampus JNK mitochondrial dynamics PKA protein phosphatases TUNEL DDE high-fat diet mitochondrial UCP2 ROS antioxidant system uncoupling protein mitochondria: energy metabolism lipid handling fatty acid oxidation potassium channel reactive oxygen species antioxidants life span aging BKCa channels pravastatin gemfibrozil liver colon mitochondrial function cyclosporin A mitochondria calcium buffering mitochondria bioenergetics mitochondria permeability transition pore inorganic phosphate hepatic fibrogenesis HtrA2/Omi reactive oxygen species stress mitochondrial homeostasis complex I (CI) deficiency metabolome and proteome profiling reactive oxygen species (ROS) respirasome assembly electron tunneling (ET) perilipin 5 lipid droplet H9c2 cardiomyoblasts adenine nucleotide translocase respiratory supercomplexes ETC complexes dentate granule cell epilepsy hyperforin LONP1 neuroprotection pilocarpine seizure siRNA cardioprotection mitochondrial permeability transition pores mitochondrial connexin 43 cardiolipin iron overload hepcidin transferrin ferritin ZIP inflammation mtDNA mitochondrial dysfunction muscle aging physical performance LHON Siberian population ancient mutation specific genetic background apoptosis human amniotic membrane mitochondrial cell death BAX BCL-2 tensile strength mitochondrial gene expression mtDNA transcription mtRNA post-transcriptional mtRNA processing dsRNA innate immunity interferon response amino acid neurotransmitter cerebellar amino acid metabolism hypoxia 2-oxoglutarate dehydrogenase tricarboxylic acid cycle heart cytoskeletal proteins mitochondrial interactions plectin tubulin beta signaling GW9662 ischemia reperfusion injury Langendorff myocardial pioglitazone redox state rosiglitazone TZD uncoupling ADP/ATP carrier KmADP dextran morphology cardiomyocytes telomere length telomerase activity development regeneration intranuclear mitochondria healthy cells electron and confocal microscopy signaling pathways ion homeostasis human diseases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557577203321 |
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Javadov Sabzali
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitogen Activated Protein Kinases
| Mitogen Activated Protein Kinases |
| Autore | Jose Lozano |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (163 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
kinase
cell differentiation p38 MSK scaffold inflammation JNK cancer MAPK ERK |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910261137703321 |
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Jose Lozano
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitogen Activated Protein Kinases : Functions in Signal Transduction and Human Diseases
| Mitogen Activated Protein Kinases : Functions in Signal Transduction and Human Diseases |
| Autore | Tikkanen Ritva |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (276 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Rabdosia inflexa
inflammation gastric ulcer cytokines MAPK NF-κB extracellular signal-regulated kinases 1/2 hyperoxia bronchopulmonary dysplasia HPAECs angiogenesis cell cycle SIRT1 oxidative stress psoriasis antimicrobial peptide cecropin A tight junction protein MEK/ERK signaling porcine intestinal epithelial cell extracellular signal-regulated kinase 5 (ERK5) Kv4.2 PC12 cells infantile myofibromatosis receptor tyrosine kinases platelet-derived growth factor receptor protein kinase inhibitors sunitinib erlotinib FR180204 U0126 targeted therapy apoptosis ERK1/2 JNKs mitochondrial dysfunction neurodegeneration neuro-inflammation p38 MAPKs Parkinson's disease mitogen-activated protein kinases (MAPKs) MAPK kinetics osteoclast differentiation bone remodeling DAPK ERK p38 JNK mitogen-activated protein kinase pathway (MAPK pathway) protein tyrosine phosphatase interacting protein 51 (PTPIP51) protein-protein interaction (PPI) cancer signaling SR CR Compatibility T2DM metabolic profiling MAPK/PI3K/Akt signaling pathway reactive oxygen species PTPN6 SRC DOK4 MKK4 MKK7 p53 DUSP1 SIRT2 atherosclerosis aortic valve sclerosis aortic valve stenosis naphthalimide-metal complex conjugates N-heterocyclic carbene mitochondria ROS p38 MAPK cancer FGF-induced signaling FRS2 phosphorylation downregulation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Mitogen Activated Protein Kinases |
| Record Nr. | UNINA-9910557405603321 |
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Tikkanen Ritva
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers
| Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers |
| Autore | Kutner Andrzej |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (450 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
alpha-ketoglutarate
cell cycle apoptosis JNK cell migration cell invasion TGF-β VEGF glycoconjugates methotrexate cancer treatment glucose metabolism drug design and discovery anticancer drugs targeted therapy Warburg effect antidepressants pyrido[1,2-c]pyrimidines dual 5-HT1A/SERT activity drug design anticancer activity lung cancer resveratrol PRI-2191 vitamin D active substance delivery systems biomedical hydrogels active substance-controlled release genistein hydrogels for cosmetology hydrogels for dermatology transdermal active substance delivery systems histone deacetylase (HDAC) depression biomarker anti-depressant therapy human DNA topoisomerase cancer drug molecular docking synthesis fluorine vitamin D3 metabolite A-ring CD-ring side-chain nanoparticles molecular modeling oxidation mechanisms electrochemistry MALDI spectroscopic data cytotoxic study self-assembled monolayer gold electrode multimodal activity calcium-sensing receptor enantiomer calcimimetic calcilytic colon cancer stereospecificity HT-29 IL-8 inflammation cyclooxygenase 1,2,4-triazole pyridazinone SAR anti-inflammatory activity antioxidant activity ADME anticancer drug antimicrobial peptide (AMP) dermaseptin frog skin peptides LHRH prostate cancer Phyllomedusa bicolor therapeutic peptides copper (II) complexes thiourea cytotoxic activity proteome analysis antimicrobial activity major latex protein Chelidonium majus greater celandine defense-related proteins alkaloids cancer cells vitamin D receptor split luciferase-based biosensor CYP24A1-dependent metabolism CYP27B1 rickets genome editing vitamin D biology and action transcription ChIP-chip analysis distal enhancers histone H3 acetylation RNA polymerase II analogue actions at genes vitamin D hormone (1,25(OH)2D3) latex antiviral proteins antimicrobial compounds cytotoxicity drug discovery CRISPR/Cas9 tetrahydro-β-carbolines Plasmodium falciparum (P. falciparum) antimalarial antiparasitic agents hemolysis vitamin D analogs 25 vitamin D 24-hydroxylase CYP24A1 proliferation high-grade serous ovarian cancer cells gold Au(III) complex colorectal cancer organometallic cancer therapy metallodrugs |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585938903321 |
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Kutner Andrzej
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Proceedings from ACCM19: Cell Cycle, DNA Damage Response and Telomeres
| Proceedings from ACCM19: Cell Cycle, DNA Damage Response and Telomeres |
| Autore | Burgess Andrew |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (153 p.) |
| Soggetto topico |
Science: general issues
Biology, life sciences |
| Soggetto non controllato |
cell cycle
telomere DNA damage mitosis JNK radiation chemotherapy PP2A |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Proceedings from ACCM19 |
| Record Nr. | UNINA-9910688578403321 |
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Burgess Andrew
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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