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Circuit Mechanisms of Neurodegenerative Diseases
| Circuit Mechanisms of Neurodegenerative Diseases |
| Autore | Liebscher Sabine |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (165 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
neurodegeneration
neural circuits Parkinson's disease Huntington's disease amyotrophic lateral sclerosis (ALS) spinocerebellar ataxia (SCA) interneurons Alzheimer's disease |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557211003321 |
Liebscher Sabine
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Clinical use of biomarkers in neurodegenerative disorders / / topic editor Manuel Menéndez-González
| Clinical use of biomarkers in neurodegenerative disorders / / topic editor Manuel Menéndez-González |
| Autore | Manuel Menendez-Gonzalez |
| Pubbl/distr/stampa | Frontiers Media SA, 2014 |
| Descrizione fisica | 1 online resource (122 pages) : illustrations; digital, PDF file(s) |
| Collana | Frontiers research topics |
| Soggetto topico |
Neurology
Medicine Health & Biological Sciences |
| Soggetto non controllato |
Neurodegenerative Diseases
neurodegenerative disease Parkinson's disease MTAi biomarker Huntington's disease CSF biomarkers Frontotemporal dementia (FTD) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137199003321 |
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Manuel Menendez-Gonzalez
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| Frontiers Media SA, 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology
| Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology |
| Autore | Fioravanti Antonella |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (320 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
miR-27a-5p
acute myocardial infarction autophagy apoptosis hypoxia MicroRNA (miRNA) miR526b miR655 oxidative stress reactive oxygen species (ROS) superoxide (SO) Thioredoxin Reductase 1 (TXNRD1) breast cancer nucleic acid medicine pancreatic cancer clinical trial siRNA antisense oligonucleotide MicroRNA signal transduction therapeutic target miRNAs ROS noncoding RNA microRNA long noncoding RNA mitochondrial dysfunction nitrosative stress. exosome cross-talk systemic lupus erythematosus visfatin resistin osteoarthritis synovial fibroblasts synovitis NF-κB thyroid hormone liver cancer metabolism physiology ASH NAFLD NASH HCC HCV HBV endometriosis high-grade serous ovarian cancer endometriosis-associated ovarian cancer epithelial-to-mesenchymal transition chemoresistance antioxidants miRNA cancer diabetes beta cells microRNAs translation regulation neurodegeneration Alzheimer's disease Parkinson's disease Huntington's disease ALS reactive oxygen species redox signaling therapeutic tolerance therapeutic resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557526003321 |
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Fioravanti Antonella
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genome Editing in Neurosciences [[electronic resource] /] / edited by Rudolf Jaenisch, Feng Zhang, Fred Gage
| Genome Editing in Neurosciences [[electronic resource] /] / edited by Rudolf Jaenisch, Feng Zhang, Fred Gage |
| Autore | Feng Zhang |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Springer Nature, 2017 |
| Descrizione fisica | 1 online resource (XI, 123 p. 16 illus. in color.) |
| Disciplina |
611.01816
599.935 |
| Collana | Research and Perspectives in Neurosciences |
| Soggetto topico |
Human genetics
Neurosciences Biomedical engineering Human Genetics Biomedical Engineering/Biotechnology |
| Soggetto non controllato |
CRISPR
muscular dystrophy Parkinson's disease DNA Rett syndrome double-strand breaks Huntington's disease genetic engineering |
| ISBN | 3-319-60192-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- In vitro modeling of complex neurological diseases -- Aquatic model organisms in neurosciences : the genome editing revolution -- Genome-wide genetic screening in the mammalian CNS -- CRISPR/Cas9-mediated Knockin and Knockout in Zebrafish -- Dissecting the role of synaptic proteins with CRISPR -- Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer -- Neuroscience research using non-human primate models and genome editing -- Multiscale genome engineering: Genome-wide screens and targeted approaches -- Using Genome Engineering to Understand Huntington’s Disease -- Therapeutic gene editing in muscles and muscle stem cells. |
| Record Nr. | UNINA-9910231247003321 |
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Feng Zhang
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| Springer Nature, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Juvenile Onset Huntington's Disease
| Juvenile Onset Huntington's Disease |
| Autore | Nopoulos Peggy C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (102 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Huntington's disease
CAG repeat mutant huntingtin (mHTT) therapeutics neurodegeneration juvenile Huntington's disease pediatric Huntington's disease early-onset Huntington's disease personal experiences caregivers case series juvenile-onset Huntington's disease T1-Rho neuroimaging behavioral regulation executive function trinucleotide repeat disorder CAG motor onset juvenile-onset Huntington's Disease autonomic |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557124503321 |
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Nopoulos Peggy C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pathophysiology of the Basal Ganglia and Movement Disorders: Gaining New Insights from Modeling and Experimentation to Influence the Clinic
| Pathophysiology of the Basal Ganglia and Movement Disorders: Gaining New Insights from Modeling and Experimentation to Influence the Clinic |
| Autore | Olivier Darbin |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (220 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Braak's hypothesis
basal ganglia Parkinson's disease cycling movement disorders computational modeling Huntington's disease non-motor symptoms nonlinear dynamics deep brain stimulation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Pathophysiology of the Basal Ganglia and Movement Disorders |
| Record Nr. | UNINA-9910261138103321 |
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Olivier Darbin
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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PLGA Based Drug Carrier and Pharmaceutical Applications
| PLGA Based Drug Carrier and Pharmaceutical Applications |
| Autore | Pereira Maria Carmo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (328 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
PLGA
nanoscaled drug delivery LED cancer serum stability reactive oxygen species cellular uptake terahertz spectroscopy microspheres drug delivery formulation development molecular mobility vitamin E tocopherol PLA core-shell nanoparticles controlled drug release BMP-2 PLGA nanoparticles Pluronic F68 oxaliplatin hydrogel intra-abdominal anti-adhesion barrier colorectal cancer experimental design fractional factorial design O6-methylguanine DNA methyltransferase (MGMT) protein glioblastoma multiforme smart nanocarriers folic acid verteporfin cisplatin SKOV-3 cells CHO-K1 cells electroporation theranostic cargo double emulsion approach NSAIDs polymeric film topical drug delivery trolamine salicylate triamcinolone acetonide microcrystal PLGA microsphere local delivery spray-drying technique intra-articular injection joint retention systemic exposure gadolinium drug release polymeric nanocarrier sorafenib theranostic nanoparticles PLGA-PEG nanoparticles platelet activation aggregation binding uptake tissue engineering Huntington's disease siRNA microcarriers mesenchymal stromal cells drug delivery systems microfluidics microparticles BMP-2-microspheres hydrogel system 17-βestradiol release bone regeneration osteoporosis poly-lactide-co-glycolide polylactic acid alginate ophthalmic drug delivery dexamethasone PLGA-NPs nanomedicine gastrointestinal tract paclitaxel in vivo imaging controlled release risperidone microcapsules oleogels electron microscopy three-dimensional X-ray imaging nano-CT biodegradable polymers hydroxy-stearic acid PLGA nanocapsules magnetic resonance imaging photoluminescence magnetic targeting multimodal imaging theranostics silicon microsphere |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557124003321 |
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Pereira Maria Carmo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Structure, Activity, and Function of Protein Methyltransferases
| Structure, Activity, and Function of Protein Methyltransferases |
| Autore | Jeltsch Albert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (292 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
protein lysine methylation
H3K9 methylation PKMT enzyme specificity enzyme regulation heterochromatin protein post-translational modification NSD3 WHSC1L1 structure and function protein arginine methylation PRMT7 epigenetics cancer immunity pluripotency SETDB1 methyltransferase schizophrenia Huntington's disease Rett syndrome Prader-Willi syndrome congenital heart diseases inflammatory bowel disease MLL2 structure H3K4me3 chromatin regulation disease dystonia NSD1 H3K36 SOTOS NUP98-NSD1 AML PRMT6 post-translational modification H3R2me2a SETD3 posttranslational modifications protein histidine methylation actin polymerization cytoskeleton enteroviruses oncogenesis PRMT5 cardiovascular disease neurodegenerative diseases diabetes inflammation G9a GLP EHMT2 EHMT1 post translational modification lysine methylation N-terminal methylation translation eEF1A METTL13 neuron synapse dendritic spine actin cytoskeleton GTPase PRMT1 arginine methylation H4R3 methylation transcriptional regulation cell signaling DNA damage repair PRMT2 SH3 SETMAR Metnase H3K36me2 Hsmar1 non-homologous end joining repair NHEJ transposase transposable elements histone SET7/9 SETD7 lysine-specific methyltransferase (PKMT) cell proliferation stress response post-translational protein modification |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566479603321 |
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Jeltsch Albert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ubiquitin and the Brain: Roles of Proteolysis in the Normal and Abnormal Nervous System
| Ubiquitin and the Brain: Roles of Proteolysis in the Normal and Abnormal Nervous System |
| Autore | Ashok N. Hegde |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (241 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
proteasome
memory neuroinflammation neurodegenerative synaptic plasticity aging deubiquitinating Huntington's disease Alzheimer's disease glutamate receptors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Ubiquitin and the Brain |
| Record Nr. | UNINA-9910261140803321 |
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Ashok N. Hegde
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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