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Circuit Mechanisms of Neurodegenerative Diseases
| Circuit Mechanisms of Neurodegenerative Diseases |
| Autore | Liebscher Sabine |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (165 p.) |
| Soggetto topico |
Neurosciences
Science: general issues |
| Soggetto non controllato |
Alzheimer's disease
amyotrophic lateral sclerosis (ALS) Huntington's disease interneurons neural circuits neurodegeneration Parkinson's disease spinocerebellar ataxia (SCA) |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557211003321 |
Liebscher Sabine
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Clinical use of biomarkers in neurodegenerative disorders / / topic editor Manuel Menéndez-González
| Clinical use of biomarkers in neurodegenerative disorders / / topic editor Manuel Menéndez-González |
| Autore | Manuel Menendez-Gonzalez |
| Pubbl/distr/stampa | Frontiers Media SA, 2014 |
| Descrizione fisica | 1 online resource (122 pages) : illustrations; digital, PDF file(s) |
| Collana | Frontiers research topics |
| Soggetto topico |
Neurology
Medicine Health & Biological Sciences |
| Soggetto non controllato |
Neurodegenerative Diseases
neurodegenerative disease Parkinson's disease MTAi biomarker Huntington's disease CSF biomarkers Frontotemporal dementia (FTD) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137199003321 |
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Manuel Menendez-Gonzalez
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| Frontiers Media SA, 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology
| Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology |
| Autore | Fioravanti Antonella |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (320 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acute myocardial infarction
ALS Alzheimer's disease antioxidants antisense oligonucleotide apoptosis ASH autophagy beta cells breast cancer cancer chemoresistance clinical trial cross-talk diabetes endometriosis endometriosis-associated ovarian cancer epithelial-to-mesenchymal transition HBV HCC HCV high-grade serous ovarian cancer Huntington's disease hypoxia liver cancer long noncoding RNA metabolism microRNA MicroRNA MicroRNA (miRNA) microRNAs miR-27a-5p miR526b miR655 miRNA miRNAs mitochondrial dysfunction n/a NAFLD NASH neurodegeneration NF-κB nitrosative stress. exosome noncoding RNA nucleic acid medicine osteoarthritis oxidative stress pancreatic cancer Parkinson's disease physiology reactive oxygen species reactive oxygen species (ROS) redox signaling resistin ROS signal transduction siRNA superoxide (SO) synovial fibroblasts synovitis systemic lupus erythematosus therapeutic resistance therapeutic target therapeutic tolerance Thioredoxin Reductase 1 (TXNRD1) thyroid hormone translation regulation visfatin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557526003321 |
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Fioravanti Antonella
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genome Editing in Neurosciences [[electronic resource] /] / edited by Rudolf Jaenisch, Feng Zhang, Fred Gage
| Genome Editing in Neurosciences [[electronic resource] /] / edited by Rudolf Jaenisch, Feng Zhang, Fred Gage |
| Autore | Feng Zhang |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Springer Nature, 2017 |
| Descrizione fisica | 1 online resource (XI, 123 p. 16 illus. in color.) |
| Disciplina |
611.01816
599.935 |
| Collana | Research and Perspectives in Neurosciences |
| Soggetto topico |
Human genetics
Neurosciences Biomedical engineering Human Genetics Biomedical Engineering/Biotechnology |
| Soggetto non controllato |
CRISPR
muscular dystrophy Parkinson's disease DNA Rett syndrome double-strand breaks Huntington's disease genetic engineering |
| ISBN | 3-319-60192-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- In vitro modeling of complex neurological diseases -- Aquatic model organisms in neurosciences : the genome editing revolution -- Genome-wide genetic screening in the mammalian CNS -- CRISPR/Cas9-mediated Knockin and Knockout in Zebrafish -- Dissecting the role of synaptic proteins with CRISPR -- Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer -- Neuroscience research using non-human primate models and genome editing -- Multiscale genome engineering: Genome-wide screens and targeted approaches -- Using Genome Engineering to Understand Huntington’s Disease -- Therapeutic gene editing in muscles and muscle stem cells. |
| Record Nr. | UNINA-9910231247003321 |
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Feng Zhang
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| Springer Nature, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Juvenile Onset Huntington's Disease
| Juvenile Onset Huntington's Disease |
| Autore | Nopoulos Peggy C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (102 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
autonomic
behavioral regulation CAG CAG repeat caregivers case series early-onset Huntington's disease executive function Huntington's disease juvenile Huntington's disease juvenile-onset Huntington's disease juvenile-onset Huntington's Disease motor onset mutant huntingtin (mHTT) n/a neurodegeneration neuroimaging pediatric Huntington's disease personal experiences T1-Rho therapeutics trinucleotide repeat disorder |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557124503321 |
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Nopoulos Peggy C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pathophysiology of the Basal Ganglia and Movement Disorders: Gaining New Insights from Modeling and Experimentation to Influence the Clinic
| Pathophysiology of the Basal Ganglia and Movement Disorders: Gaining New Insights from Modeling and Experimentation to Influence the Clinic |
| Autore | Olivier Darbin |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 online resource (220 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Neurosciences |
| Soggetto non controllato |
basal ganglia
Braak's hypothesis computational modeling cycling deep brain stimulation Huntington's disease movement disorders non-motor symptoms nonlinear dynamics Parkinson's disease |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Pathophysiology of the Basal Ganglia and Movement Disorders |
| Record Nr. | UNINA-9910261138103321 |
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Olivier Darbin
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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PLGA Based Drug Carrier and Pharmaceutical Applications
| PLGA Based Drug Carrier and Pharmaceutical Applications |
| Autore | Pereira Maria Carmo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (328 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
17-βestradiol release
activation aggregation alginate binding biodegradable polymers BMP-2 BMP-2-microspheres bone regeneration cancer cellular uptake CHO-K1 cells cisplatin colorectal cancer controlled drug release controlled release core-shell nanoparticles dexamethasone double emulsion approach drug delivery drug delivery systems drug release electron microscopy electroporation experimental design folic acid formulation development fractional factorial design gadolinium gastrointestinal tract glioblastoma multiforme Huntington's disease hydrogel hydrogel system hydroxy-stearic acid in vivo imaging intra-abdominal anti-adhesion barrier intra-articular injection joint retention LED local delivery magnetic resonance imaging magnetic targeting mesenchymal stromal cells microcapsules microcarriers microcrystal microfluidics microparticles microsphere microspheres molecular mobility multimodal imaging n/a nano-CT nanomedicine nanoparticles nanoscaled drug delivery NSAIDs O6-methylguanine DNA methyltransferase (MGMT) protein oleogels ophthalmic drug delivery osteoporosis oxaliplatin paclitaxel photoluminescence PLA platelet PLGA PLGA microsphere PLGA nanocapsules PLGA nanoparticles PLGA-NPs PLGA-PEG Pluronic F68 poly-lactide-co-glycolide polylactic acid polymeric film polymeric nanocarrier reactive oxygen species risperidone serum stability silicon siRNA SKOV-3 cells smart nanocarriers sorafenib spray-drying technique systemic exposure terahertz spectroscopy theranostic cargo theranostic nanoparticles theranostics three-dimensional X-ray imaging tissue engineering tocopherol topical drug delivery triamcinolone acetonide trolamine salicylate uptake verteporfin vitamin E |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557124003321 |
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Pereira Maria Carmo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Structure, Activity, and Function of Protein Methyltransferases
| Structure, Activity, and Function of Protein Methyltransferases |
| Autore | Jeltsch Albert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (292 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research & information: general |
| Soggetto non controllato |
actin
actin cytoskeleton AML arginine methylation cancer cardiovascular disease cell proliferation cell signaling chromatin regulation congenital heart diseases cytoskeleton dendritic spine diabetes disease DNA damage repair dystonia eEF1A EHMT1 EHMT2 enteroviruses enzyme regulation enzyme specificity epigenetics G9a GLP GTPase H3K36 H3K36me2 H3K4me3 H3K9 methylation H3R2me2a H4R3 methylation heterochromatin histone Hsmar1 Huntington's disease immunity inflammation inflammatory bowel disease lysine methylation lysine-specific methyltransferase (PKMT) methyltransferase Metnase METTL13 MLL2 N-terminal methylation n/a neurodegenerative diseases neuron NHEJ non-homologous end joining repair NSD1 NSD3 NUP98-NSD1 oncogenesis PKMT pluripotency polymerization post translational modification post-translational modification post-translational protein modification posttranslational modifications Prader-Willi syndrome PRMT1 PRMT2 PRMT5 PRMT6 PRMT7 protein arginine methylation protein histidine methylation protein lysine methylation protein post-translational modification Rett syndrome schizophrenia SET7/9 SETD3 SETD7 SETDB1 SETMAR SH3 SOTOS stress response structure structure and function synapse transcriptional regulation translation transposable elements transposase WHSC1L1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566479603321 |
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Jeltsch Albert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ubiquitin and the Brain: Roles of Proteolysis in the Normal and Abnormal Nervous System
| Ubiquitin and the Brain: Roles of Proteolysis in the Normal and Abnormal Nervous System |
| Autore | Ashok N. Hegde |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 online resource (241 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Neurosciences |
| Soggetto non controllato |
aging
Alzheimer's disease deubiquitinating glutamate receptors Huntington's disease memory neurodegenerative neuroinflammation proteasome synaptic plasticity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Ubiquitin and the Brain |
| Record Nr. | UNINA-9910261140803321 |
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Ashok N. Hegde
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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