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Disease and the Hippo Pathway: Cellular and Molecular Mechanisms
| Disease and the Hippo Pathway: Cellular and Molecular Mechanisms |
| Autore | Hansen Carsten Gram |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (226 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
adaptive immunity
angiogenesis anti-cancer therapy autoimmunity cancer cancer immunity castration resistance chromatin ECM EMT epigenetic feedback loops fibroblasts fibrosis G protein-coupled receptor GPCR Hippo hippo pathway Hippo pathway Hippo signalling innate immunity LATS LATS (large tumor suppressor kinase) LATS1/2 Lats2 Mps one binder MST MST (mammalian STE20-like protein kinase) MST1/2 myofibroblast n/a NDR peripheral nerve sheath tumor phosphorylation prostate cancer protein kinase protein-protein interactions schwannoma signal cross-talk signal transduction skin cancer skin development stem cell stem cells STK38 STRIPAK structure biology Taz TAZ TAZ (transcriptional co-activator with PDZ-binding motif) TEAD transcription tumorigenesis vascular mimicry wound healing Yap YAP YAP (yes-associated protein) YAP/TAZ zebrafish |
| ISBN | 3-03921-777-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Disease and the Hippo Pathway |
| Record Nr. | UNINA-9910367742003321 |
Hansen Carsten Gram
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kidney Inflammation, Injury and Regeneration 2020
| Kidney Inflammation, Injury and Regeneration 2020 |
| Autore | Baer Patrick C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (318 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
ACEI
acute kidney injury adaptive immunity anemia anemia of inflammation angiotensin II apoptosis autophagy B cells BAFF Bcl-XL biomarker chemokines chronic kidney disease cilastatin CKD coinhibition corticosteroids costimulation cyclophilin A cytochrome C diabetic nephropathy dieckol DJ-1 E. cava extracts endocan endotoxin epithelial-to-mesenchymal transition ERK ESA hyporesponsiveness ESM-1 extracellular matrix fibrosis focal segmental glomerulosclerosis FSGS glomerulonephritis Hippo pathway hypercholesterolemia hypoxia inducible factor-1-α IgAN inflammation innate immunity iron ischemia-reperfusion injury kidney fibrosis kidney transplant kidney transplantation lipocalin-2 macrophages membranous nephropathy minimal change diseases ML171 myofibroblast activation n/a ND-13 NF-κB pathway NOX1 oxidative stress podocytes preeclampsia progression protein binding affinity proteinuria reactive oxygen species renal disease renal fibrosis renal inflammation renal replacement therapy renal tubular epithelial cells simvastatin spontaneously hypertensive rats SPR survivin T cells tertiary lymphoid organs TLR trehalose tubular apoptosis tubular necrosis UUO VEGF verteporfin xanthine oxidase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557364503321 |
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Baer Patrick C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges
| Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges |
| Autore | Gabazza Esteban C |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (348 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acute lung injury
anaplastic lymphoma kinase angiogenesis antitumor efficacy apoptosis bleomycin breast cancer butylidenephthalide cancer cancer-associated fibroblasts cancer-associated fibroblasts (CAFs) carcinogenesis cirrhosis clinical symptoms common pathways crizotinib cystic formation cytokine cytokines DHA diagnosis EMT Erk1/2 extracellular matrix fibrosis genetic instability GPR120 GPR40 growth factor HBV HCV hepatic stellate cells hepatic stellate cells (HSCs) hepatocellular carcinoma hepatocellular carcinoma (HCC) hepatocytes heterogeneity Hippo pathway idiopathic pulmonary fibrosis idiopathic pulmonary fibrosis (IPF) immunohistochemistry inflammation interstitial fluid pressure leiomyoma leiomyosarcoma lipopolysaccharide lncRNA lung cancer lung cancer (LC) marker mechanotransduction metabolic reprogramming metastasis miRNA myometrium n/a nanoparticles non-alcoholic steatohepatitis non-small cell lung cancer (NSCLC) omega-3 fatty acid pathogenesis pathology pathophysiology protein S pulmonary fibrosis reactive oxygen species regeneration renal injury signal pathway SMAD smooth muscle tumor of uncertain malignant potential SOX2 SREBP-1 targeted therapy TAZ TGF-? therapy transforming growth factor-? tumor tumor microenvironment tumor necrosis factor ? tumor stiffness type I collagen uterine fibroid Wnt YAP |
| ISBN | 3-03921-707-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Links between Fibrogenesis and Cancer |
| Record Nr. | UNINA-9910367745903321 |
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Gabazza Esteban C
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Malignant Mesothelioma
| Malignant Mesothelioma |
| Autore | L. Pouliquen Daniel |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (328 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
asbestos
asbestos exposure BAP1 biomarkers cancer biomarkers cancer-specific mutations cancers carbon nanotubes carcinogenesis CDKN2A circulating tumor DNA dendritic cells DNA damage response DNA methylation DNA sequencing drug repurposing epigenome-wide analysis epithelioid extrapleural pneumonectomy fatty acid-binding protein FDG first line gene expression genomics Hippo pathway histotype immune therapy immunogenicity immunohistochemistry immunotherapy infiltrating immune cells inflammation interaction analysis laminin subunit beta-2 liquid biopsies lurbinectedin lymphocyte-to-monocyte ratio macrophage-capping protein malignant mesothelioma malignant pleural mesothelioma mesothelioma mesothelium meta-analysis metabolomics MPM MTAP mutation n/a network analysis NF2 oxidative stress PET-CT plasma pleural effusion pleural mesothelioma pleurectomy decortication predictive biomarker prognostic biomarker protein-protein interactions proteomics PTCH1 radiotherapy redox-sensitive factors sarcomatoid selenium-binding protein 1 SETD2 survival survival analysis systematic review systems biology targeted therapy therapy response tumor microenvironment tumor suppressor tumor-associated macrophages VATS WDPM well-differentiated papillary mesothelioma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557359303321 |
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L. Pouliquen Daniel
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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