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Disease and the Hippo Pathway: Cellular and Molecular Mechanisms
| Disease and the Hippo Pathway: Cellular and Molecular Mechanisms |
| Autore | Hansen Carsten Gram |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (226 p.) |
| Soggetto non controllato |
STRIPAK
skin cancer Lats2 transcription myofibroblast epigenetic Hippo cancer immunity TAZ Taz TAZ (transcriptional co-activator with PDZ-binding motif) adaptive immunity fibroblasts innate immunity LATS MST (mammalian STE20-like protein kinase) phosphorylation stem cells wound healing signal transduction angiogenesis LATS1/2 EMT protein-protein interactions structure biology Hippo pathway hippo pathway autoimmunity Mps one binder YAP/TAZ GPCR fibrosis MST1/2 YAP (yes-associated protein) YAP Yap protein kinase LATS (large tumor suppressor kinase) peripheral nerve sheath tumor signal cross-talk stem cell skin development STK38 tumorigenesis NDR schwannoma G protein-coupled receptor anti-cancer therapy feedback loops vascular mimicry castration resistance chromatin Hippo signalling ECM MST prostate cancer TEAD cancer zebrafish |
| ISBN | 3-03921-777-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Disease and the Hippo Pathway |
| Record Nr. | UNINA-9910367742003321 |
Hansen Carsten Gram
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kidney Inflammation, Injury and Regeneration 2020
| Kidney Inflammation, Injury and Regeneration 2020 |
| Autore | Baer Patrick C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
inflammation
chronic kidney disease anemia anemia of inflammation ESA hyporesponsiveness renal tubular epithelial cells macrophages lipocalin-2 iron cilastatin hypoxia inducible factor-1-α ischemia-reperfusion injury acute kidney injury cyclophilin A fibrosis renal fibrosis tubular necrosis preeclampsia podocytes VEGF FSGS proteinuria endocan ESM-1 renal replacement therapy kidney transplantation biomarker diabetic nephropathy focal segmental glomerulosclerosis innate immunity membranous nephropathy minimal change diseases TLR NOX1 ML171 reactive oxygen species ERK T cells glomerulonephritis chemokines renal disease DJ-1 ND-13 renal inflammation oxidative stress UUO autophagy apoptosis trehalose simvastatin endotoxin tubular apoptosis cytochrome C Bcl-XL survivin hypercholesterolemia xanthine oxidase NF-κB pathway tertiary lymphoid organs B cells BAFF kidney fibrosis myofibroblast activation extracellular matrix Hippo pathway verteporfin IgAN CKD progression ACEI corticosteroids costimulation coinhibition kidney transplant SPR protein binding affinity adaptive immunity epithelial-to-mesenchymal transition E. cava extracts dieckol spontaneously hypertensive rats angiotensin II |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557364503321 |
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Baer Patrick C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges
| Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges |
| Autore | Gabazza Esteban C |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (348 p.) |
| Soggetto non controllato |
bleomycin
regeneration antitumor efficacy lung cancer SOX2 leiomyosarcoma lung cancer (LC) nanoparticles cytokines hepatocellular carcinoma metabolic reprogramming hepatic stellate cells angiogenesis transforming growth factor-? anaplastic lymphoma kinase idiopathic pulmonary fibrosis growth factor pathogenesis cancer-associated fibroblasts fibrosis lipopolysaccharide DHA lncRNA SREBP-1 YAP protein S non-small cell lung cancer (NSCLC) omega-3 fatty acid inflammation metastasis clinical symptoms miRNA smooth muscle tumor of uncertain malignant potential Wnt interstitial fluid pressure heterogeneity hepatocytes myometrium tumor necrosis factor ? tumor tumor microenvironment extracellular matrix TAZ carcinogenesis cystic formation pulmonary fibrosis HBV cytokine genetic instability diagnosis EMT crizotinib Hippo pathway GPR120 marker HCV non-alcoholic steatohepatitis pathology common pathways apoptosis type I collagen GPR40 acute lung injury uterine fibroid renal injury pathophysiology reactive oxygen species immunohistochemistry SMAD butylidenephthalide leiomyoma cirrhosis Erk1/2 targeted therapy TGF-? mechanotransduction therapy breast cancer hepatocellular carcinoma (HCC) hepatic stellate cells (HSCs) idiopathic pulmonary fibrosis (IPF) cancer-associated fibroblasts (CAFs) cancer signal pathway tumor stiffness |
| ISBN | 3-03921-707-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Links between Fibrogenesis and Cancer |
| Record Nr. | UNINA-9910367745903321 |
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Gabazza Esteban C
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Malignant Mesothelioma
| Malignant Mesothelioma |
| Autore | L. Pouliquen Daniel |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (328 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
well-differentiated papillary mesothelioma
WDPM malignant mesothelioma DNA sequencing mutation mesothelioma tumor suppressor targeted therapy immunotherapy biomarkers proteomics macrophage-capping protein fatty acid-binding protein laminin subunit beta-2 selenium-binding protein 1 carcinogenesis malignant pleural mesothelioma asbestos exposure DNA methylation lymphocyte-to-monocyte ratio epigenome-wide analysis survival analysis metabolomics radiotherapy cancers inflammation infiltrating immune cells prognostic biomarker predictive biomarker immune therapy VATS extrapleural pneumonectomy pleurectomy decortication therapy response survival FDG PET-CT mesothelium oxidative stress redox-sensitive factors asbestos carbon nanotubes protein-protein interactions systems biology network analysis drug repurposing pleural mesothelioma gene expression immunogenicity sarcomatoid epithelioid first line meta-analysis systematic review MPM lurbinectedin DNA damage response histotype Hippo pathway NF2 BAP1 CDKN2A PTCH1 SETD2 MTAP liquid biopsies circulating tumor DNA plasma cancer-specific mutations genomics cancer biomarkers tumor microenvironment tumor-associated macrophages dendritic cells immunohistochemistry interaction analysis pleural effusion |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557359303321 |
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L. Pouliquen Daniel
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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