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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials
| From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials |
| Autore | FESSARD Valérie |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
graphene oxide
reduced graphene oxide micronucleus oxidative stress safer-by-design tungsten nanoparticles tritiated particles in vitro testing cytotoxicity micronuclei formation DNA damage epigenetics DNA methylation BEAS-2B cells polystyrene nanoparticles nanoplastics genotoxicity Hs27 human fibroblasts comet assay FPG enzyme TiO2NP SiO2NP ZnONP CeO2NP AgNP multi-walled carbon nanotubes (MWCNT) titanium dioxide nanoparticles lincomycin human amniotic cells in vitro genotoxicity apoptosis nanotoxicology metal oxides high throughput screening micronucleus assay nanomaterial aluminum oral route gut liver V79 cells Hprt advanced in vitro model hepatotoxicity liver spheroids 3D culture HepG2 nongenotoxic silver nanoparticles genotoxic cytotoxic antioxidant activity silver ions Allium cepa metal/coating agent ratio |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557414003321 |
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FESSARD Valérie
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Functional Cereal Foods for Health Benefits: Genetic and/or Processing Strategies to Enhance the Quali-Quantitative Composition of Bioactive Components
| Functional Cereal Foods for Health Benefits: Genetic and/or Processing Strategies to Enhance the Quali-Quantitative Composition of Bioactive Components |
| Autore | Laddomada Barbara |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
coix seed
Monascus purpureus antioxidant fermentation HEp2 buckwheat dehulling germination LC-MS free phenolic bound phenolic antioxidant activity sorghum phenolic compounds cell growth inhibition cell cycle analysis apoptosis HepG2 Caco-2 wheat nutrients celiac disease wheat allergy non-celiac wheat/gluten sensitivity durum wheat milling fractions air-classification plant micronization plant sorghum phenolics anti-inflammatory anti-proliferative anti-diabetic anti-atherogenic Triticum aestivum L. Triticum durum Desf gluten breadmaking durum grains genetic variability heritability climate constraints yield performance air-classified fractions alveographic properties antioxidants starch ATI glutenins gluten strength grain protein content haplotypes SNPs milling methods dietary fiber phenolic acid steamed bread leavened pancake multiple linear regression (MLR) artificial neural network (ANN) milled rice enzymes air classification inorganic contaminants organic contaminants arsenic mycotoxins maize inbred lines nutritional value protein quality |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Functional Cereal Foods for Health Benefits |
| Record Nr. | UNINA-9910585944403321 |
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Laddomada Barbara
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Advances in the Research of Antioxidant Food Peptides
| New Advances in the Research of Antioxidant Food Peptides |
| Autore | Amigo Lourdes |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (154 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
food peptides
reactive oxygen species antioxidant enzymes whey protein hydrolysate hydrolysis condition food antioxidant ORAC cellular ROS HepG2 peptides egg white egg yolk antioxidant peptides sarcopenia whey protein muscle C2C12 aged animals older adult exercise bioactive peptides animal protein multifunctionality antioxidant activity in silico cell models fruit residues antioxidant extraction albumin albumin peptide antioxidant peptide bioactive peptide mung bean mung bean albumin peptide sequencing Vigna radiata |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557793003321 |
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Amigo Lourdes
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Anti-cancer Agents and Cellular Targets and Their Mechanism(s) of Action
| Novel Anti-cancer Agents and Cellular Targets and Their Mechanism(s) of Action |
| Autore | Allison Simon J |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (206 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
microtubule acetylation
triple-negative breast cancer anti-cancer agent apoptosis K562 8-hydroxydaidzein autophagy BCR-ABL MAPK NF-κB c-myc RNA interference siRNA oncogene gene silencing expression nanosystems Cytochrome P450 CYP1A1 CYP1B1 CYP2W1 breast cancer prodrug bioprecursor duocarmycin phortress AQ4N 5-FU resistance colorectal cancer drug repurposing Genomics of Drug Sensitivity in Cancer Connectivity Map anticancer drug B-lactam steroid alkylators synthetic lethality poly (ADP-ribose) polymerase inhibitors ovarian cancer hybrid steroidal alkylating agents migration invasion glioblastoma CCN1 mesenchymal-amoeboid transition biomarker HepG2 Huh7 isatin sulfonamides angiogenesis cancer hallmarks molecular docking EGFR tyrosine kinase inhibitor photon upconversion triplet-triplet annihilation in vivo imaging PLGA nanoparticles affibody molecule human epidermal growth factor receptor 3 (HER3) BxPC-3 emtansine DM1 albumin binding domain affibody drug conjugate (AffiDC) |
| ISBN | 3-0365-5222-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Novel Anti-cancer Agents and Cellular Targets and Their Mechanism |
| Record Nr. | UNINA-9910619465503321 |
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Allison Simon J
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Essential Oil with Biological Activity
| Plant Essential Oil with Biological Activity |
| Autore | Elshafie Hazem Salaheldin |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (264 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
allelopathy
bioherbicides volatile oils terpenes aromatic plants Curcuma longa essential oil extraction methods chemical composition agri-food industry antimicrobial herbicidal antioxidant horseweed wavy-leaf fleabane sesquiterpenes cytotoxicity anti-senility tomato eco-friendly product essential oils quality preservation antioxidants damage index phytotoxicity environmental factors Cleome genus anti-inflammation Oncosiphon suffruticosum antibacterial tyrosinase inhibition sun protection factor medicinal plants GC-MS postharvest diseases biological control cell membrane permeability pale smartweed green chemistry herbicides Jungia rugosa Jungia bullata Jungia jelskii Jungia malvifolia Asteraceae enantiomers Ecuador Pulicaria crispa chemometric analysis chemotype Aerva javanica sandy soil hydrodistillation antioxidant activity seasonal variation angustione trichomes fruit storage natural products quality-related attributes volatiles Anisosciadium lanatum HepG2 BCL-2 CASPASE-3 apoptotic markers WRKY transcription factor Fusarium root rot Mentha spicata Mentha longifolia GC–MS antioxidant enzymes antifungal activity Annona cherimola enantioselective analysis antibacterial activity anticholinesterase activity germacrene D Campylobacter jejuni antimicrobial activity phytopathogens food preservatives |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566457203321 |
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Elshafie Hazem Salaheldin
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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