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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular Oxidative Stress
| Cellular Oxidative Stress |
| Autore | Marino Angela |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (529 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
neuroinflammation
clinical palmitoylethanolamide luteolin co-ultramicronization CNS pathology adaptive immune response cell homeostasis legumes liver hepatic steatosis lipid dyshomeostasis ROS traumatic brain injury palmitoylethanolamide (PEA) therapeutic strategies oxidative stress RNA-Seq RPE Retinitis pigmentosa A2E diabetes glucose exposure Band 3 protein erythrocytes SO42− 4-hydroxy-2-nonenal 3-glutathionyl-4-hydroxynonanal astrocytoma cells soy soybeans soy foods antioxidants reactive oxygen species cardiovascular diseases cancer paw edema cashew nuts antioxidant inflammation polyphenols analgesic d-Galactose glycation SO42− uptake anion exchange diseases immune system NF-κB cigarette smoke extract nasal fibroblasts tissue inhibitor of metalloproteinases matrix metalloproteinase steroids Plasmodium falciparum syk kinase inhibitors artemisinin derivatives hemichromes cellular redox state mitochondrial function cisplatin nephrotoxicity acute pancreatitis obesity nitrosative stress PGC-1α microparticles vesiculation band 3 tert-Bytyl hydroperoxide t-BOOH nitric oxide donor calcium ionophore A23187 age-related macular degeneration (AMD) diet Substance-P adipose-derived stem cells paracrine factors epilepsy status epilepticus Trolox HeLa prooxidant AVD apoptosis neurodegeneration ncRNA miRNA tRNA fragments lncRNA circRNA preeclampsia hemostasis platelets coagulation fish mucosal immunity nasal immunity peroxide vitamin C NAC immunosenescence T cells vaccination aging microvascular permeability bradykinin interleukin 1β NADPH oxidase simvastatin molecular hydrogen autophagy matrix metalloproteinases reactive oxygen species (ROS) phytochemicals dietary chemicals natural compounds programmed cell death anoikis ferroptosis pyroptosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557338703321 |
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Marino Angela
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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