Application of Bioinformatics in Cancers |
Autore | Brenner J. Chad |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
Descrizione fisica | 1 electronic resource (418 p.) |
Soggetto non controllato |
cancer treatment
extreme learning independent prognostic power AID/APOBEC HP gene inactivation biomarkers biomarker discovery chemotherapy artificial intelligence epigenetics comorbidity score denoising autoencoders protein single-biomarkers gene signature extraction high-throughput analysis concatenated deep feature feature selection differential gene expression analysis colorectal cancer ovarian cancer multiple-biomarkers gefitinib cancer biomarkers classification cancer biomarker mutation hierarchical clustering analysis HNSCC cell-free DNA network analysis drug resistance hTERT variable selection KRAS mutation single-cell sequencing network target skin cutaneous melanoma telomeres Neoantigen Prediction datasets clinical/environmental factors StAR PD-L1 miRNA circulating tumor DNA (ctDNA) false discovery rate predictive model Computational Immunology brain metastases observed survival interval next generation sequencing brain machine learning cancer prognosis copy number aberration mutable motif steroidogenic enzymes tumor mortality tumor microenvironment somatic mutation transcriptional signatures omics profiles mitochondrial metabolism Bufadienolide-like chemicals cancer-related pathways intratumor heterogeneity estrogen locoregionally advanced RNA feature extraction and interpretation treatment de-escalation activation induced deaminase knockoffs R package copy number variation gene loss biomarkers cancer CRISPR overall survival histopathological imaging self-organizing map Network Analysis oral cancer biostatistics firehose Bioinformatics tool alternative splicing biomarkers diseases genes histopathological imaging features imaging TCGA decision support systems The Cancer Genome Atlas molecular subtypes molecular mechanism omics curative surgery network pharmacology methylation bioinformatics neurological disorders precision medicine cancer modeling miRNAs breast cancer detection functional analysis biomarker signature anti-cancer hormone sensitive cancers deep learning DNA sequence profile pancreatic cancer telomerase Monte Carlo mixture of normal distributions survival analysis tumor infiltrating lymphocytes curation pathophysiology GEO DataSets head and neck cancer gene expression analysis erlotinib meta-analysis traditional Chinese medicine breast cancer TCGA mining breast cancer prognosis microarray DNA interaction health strengthening herb cancer genomic instability |
ISBN | 3-03921-789-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cancer Biomarker Research and Personalized Medicine |
Autore | Meehan James |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (428 p.) |
Soggetto topico |
Medicine
Oncology |
Soggetto non controllato |
clear cell renal cell carcinoma
radiomics WHO/ISUP nuclear grade multiphasic multidetector computed tomography triple-negative breast cancer taxane chemotherapy GBP5 Akt/mTOR autophagy IL13Rα2 renal cell carcinoma JAK2 FOXO3 telmisartan ovarian cancer bioinformatics CREB1 drug perturbation lincRNA-p21 rectal cancer chemoradiotherapy colorectal cancer long non-coding RNA p53 predictive biomarker intestinal anastomosis anastomotic leak biomarkers precision medicine personalized medicine biomarker AmpliSeq DNA methylation epigenetics head and neck cancer saliva liquid biopsy meta-analysis gastric cancer middle-up-down haptoglobin glycopeptide mass spectrometry circulating tumor cells prostate cancer cancer vaccine immune response breast cancer predictive tools prognostic tools translational research IL6ST gp130 cytokine signalling tissue-based biomarkers liquid-based biomarkers radiotherapy radiosensitivity biomarkers secretome radioresistance bladder tumor lymphocyte-to-monocyte ratio peripheral blood parameters tumor recurrence transurethral resection lipidomics 1H-NMR LC-MS/MS lipoprotein subfractions lipoprotein lipase cancer biomarkers hepatocellular carcinoma p16 expression head and neck squamous cell carcinoma HPV genotyping exosomes chemoresistance comparative oncology One Health microRNA lymph node metastasis hormone-dependent carcinogenesis localized prostate cancer prognostic factors HNSCC |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910674370003321 |
Meehan James | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Critical Issues in Head and Neck Oncology [[electronic resource] ] : Key Concepts from the Seventh THNO Meeting / / edited by Jan B. Vermorken, Volker Budach, C. René Leemans, Jean-Pascal Machiels, Piero Nicolai, Brian O’Sullivan |
Autore | Vermorken Jan B |
Edizione | [1st ed. 2021.] |
Pubbl/distr/stampa | Springer Nature, 2021 |
Descrizione fisica | 1 online resource (IX, 373 p. 39 illus., 33 illus. in color.) |
Disciplina | 616.994 |
Soggetto topico |
Oncology
Radiotherapy Surgical oncology Oncology Surgical Oncology Càncer de coll Càncer de cap Cirurgia oncològica |
Soggetto genere / forma | Llibres electrònics |
Soggetto non controllato |
Oncology
Radiotherapy Surgical Oncology Internal Medicine Radiology Surgery Nasopharynx cancer Head and Neck Squamous Cell Cancer non-oropharyngeal head and neck cancer predictive biomarkers liquid biopsies induction chemotherapy immunotherapy precision medicine HNSCC Open Access |
ISBN | 3-030-63234-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Biomarkers in Head and Neck Squamous Cell Cancer (HNSCC) -- Promising biomarkers for early diagnosis and prognosis prediction in HNS -- Biomarkers to predict radiotherapy toxicity -- Biomarkers for hypoxia, HPVness and proliferation from imaging perspective -- Mechanism of cetuximab resistance and how to overcome it -- The role of liquid biopsy for monitoring disease evolution -- NK cells in immunotherapy: how important are they? -- Biomarkers for immune modulatory treatment in HNSCC -- Primary disease (1) -- Novel approaches in surgical management of HNSCC -- The surgical approach to elderly patients with HNSCC -- The nonsurgical approach to locoregionally advanced HNSCC -- High-dose three-weekly or low-dose weekly cisplatin during radiation, what to prefer? -- Primary disease (2) -- Where and when to use induction chemotherapy? -- Prognostic role of p16/HPV in non-oropharyngeal head and neck cancer -- Is there a role for neoadjuvant targeted and immunotherapies? -- Is there a role for adjuvant targeted and immunotherapies? -- Optimal supportive measures during primary treatment -- Precision Medicine in head and neck cancer: myth or reality -- Recurrent and / or metastatic disease -- Salvage surgery: candidates, safe reconstruction, and results? -- Re-irradiation for local relapses or second primaries: when and how? -- New promising targeted agents in first and second-line settings -- Update of immune therapies in recurrent/metastatic HNSCC -- Special Issue -- Patients with rare head neck cancers: do they need a different approach? .-Nasopharynx cancer -- New epidemiological aspects -- New developments in the management of nasopharyngeal carcinoma -- New drugs for recurrent/metastatic nasopharynx cancer. |
Record Nr. | UNINA-9910484360603321 |
Vermorken Jan B | ||
Springer Nature, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Head and Neck Critical Illness : Basic and Clinical Research Implications |
Autore | Tomita Hiroyuki |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (258 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
BDNF
Brain-Derived Neurotrophic Factor navigation spatial processing trauma trauma processing Post-Traumatic Stress Disorder PSTD allocentric hippocampus sinonasal tract malignant tumor CT MRI neuropsychiatric presentation of encephalitis paraneoplastic encephalitis autoimmune encephalitis infectious encephalitis diffuse large B-cell lymphoma canaloplasty non-perforating surgical procedures corticosteroid-induced glaucoma Schlemm’s canal neck mass diffusion-weighted MRI apparent diffusion coefficient procalcitonin bacterial meningitis viral meningitis antibiotic therapy biomarker differential diagnosis human papillomavirus human cancer head and neck reduction therapy head and neck squamous cell carcinoma (HNSCC) neutrophil-to-lymphocyte ratio (NLR) myeloid-derived suppressor cells (MDSC) aldehyde dehydrogenase 1 (ALDH1) prognosis prodigiosin doxorubicin priming influx autophagy cervical cellulitis abscess deep neck infection diabetes mellitus MAP1LC3B SQSTM1 subsites tumorigenesis oral cancer Nox4 oral tongue cancer squamous cell carcinoma surgery head and neck squamous cell carcinoma HPV 11q13 gene amplification immunohistochemistry head and neck cancer radiotherapy neutrophil/lymphocyte ratio survival ZFAND4 ANUBL1 oral squamous cell carcinoma nucleotide excision repair genetic polymorphism concurrent chemoradiotherapy HNSCC MIF 4-IPP metabolism annexin A9 annexin A10 differentiation grade NGS |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Head and Neck Critical Illness |
Record Nr. | UNINA-9910557535203321 |
Tomita Hiroyuki | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Precision Medicine in Solid Tumors |
Autore | Dey Nandini |
Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
Descrizione fisica | 1 electronic resource (304 p.) |
Soggetto topico |
Medicine
Oncology |
Soggetto non controllato |
pediatric tumors
tumor mutational burden TMB whole-exome sequencing gene panel sequencing immune checkpoint inhibitors glioblastoma prognosis overall survival extent of resection random forest Decision tree personalized precision oncology circulating free DNA liquid biopsy epidermal growth factor receptor tyrosine kinase inhibitor osimertinib comprehensive genomic profiling molecular genotyping intratumor heterogeneity multiple biopsies tumor evolution clonality classification strategic therapeutic intervention thymoma driver mutation sequencing molecular barcoding EGFR mutation EGFR-TKI cfDNA NGS digital enrichment next-generation sequencing solid cancer universal health-care system precision medicine presumed germline findings clinical guideline non-small cell lung cancer outcome adjuvant chemotherapy anaplastic lymphoma receptor tyrosine kinase HNSCC ctDNA tDNA DDR genes PARP inhibitors new drug development next-generation sequencing (NGS) open data regulatory reform tumor profiling test triple-negative breast cancer (TNBC) breast cancer targeted therapy TNBC subtypes immunotherapy cancer screening smoking electronic records PD-L1 cancer-associated fibroblasts resistance chemotherapy CTC immunocytochemistry parallel double-detection laboratory-friendly |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910595078103321 |
Dey Nandini | ||
Basel, : MDPI Books, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Treatments for Squamous Cell Cancer |
Autore | Darido Charbel |
Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
Descrizione fisica | 1 electronic resource (168 p.) |
Soggetto topico |
Medicine
Oncology |
Soggetto non controllato |
oral cancer
tobacco alcohol human papilloma virus targeted sequencing DNA copy number TP53 CDKN2A EGFR PIK3CA anal cancer radiation therapy chemoradiation de-escalation of therapy pain cathepsin S protease-activated receptor-2 PAR2 cancer pain oral squamous cell carcinoma differentiation terminal differentiation oral epithelium epithelial integrity epithelial transformation genetic alterations therapy response biomarkers cutaneous squamous cell carcinoma immunotherapy anti-PD1 biomarkers predictive medicine personalized medicine cancer immune system HNSCC farnesyl transferase tipifarnib combination regimen oropharynx neoplasm squamous cell carcinoma human papillomavirus therapeutic management treatment selection CSCC treatment advances biology immunocompromised immune checkpoint inhibition |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910595074003321 |
Darido Charbel | ||
Basel, : MDPI Books, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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