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Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches
| Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches |
| Autore | Jeon Byeong Hwa |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico |
Technology: general issues
Biotechnology |
| Soggetto non controllato |
endothelial cells
oxidative stress inflammageing endothelial dysfunction aldehyde dehydrogenase-2 cardiovascular disease neurovascular disease vascular inflammation APE1/Ref-1 cardiovascular diseases subcellular localization serological biomarkers atherosclerosis aerobic exercise PCSK9 LOX-1 insulin resistance macrophage polarity serum γ-glutamyltransferase essential hypertension cardiovascular risk factors angiogenesis nargenicin A1 compound 9 VEGF VEGFR2 HIF-1α electronegative low-density lipoprotein LDL(-) L5 LDL oxidized LDL oxLDL ADMA arginine arginine paradox BH4 blood pressure COVID-19 dietary supplements endothelium eNOS uncoupling heart failure hypertension L-arginine myocardial infarction NADPH nitric oxide peripheral artery disease ApoE knockout mouse atorvastatin VCAM-1 galectin-3 neutrophil/lymphocyte ratio electronegative LDL LDL(−) lectin-like oxLDL receptor-1 dyslipidemia chronic venous insufficiency prolyl oligopeptidase (POP) inflammation endothelial disfunction lung disease endothelial to mesenchymal transition pulmonary hypertension pulmonary fibrosis metformin diabetes CV risk hyperglycemia glycated lipoproteins glycated LDL glycated HDL endothelial cell dysfunction molecular mechanisms epigenetic factors therapeutic approaches vasoactive factors EndoMT TGF-β epigenetics endothelial cell glycolysis metabolism pathological angiogenesis tumor microenvironment MRI (magnetic resonance imaging) high-fat diets plaque burden low-level laser therapy phototherapy vascular disease healing ischemia vascular calcification chronic kidney disease CKD uremic toxins hyperphosphatemia vascular smooth muscle cells VSMCs macrophages |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Endothelial Dysfunction |
| Record Nr. | UNINA-9910566471803321 |
Jeon Byeong Hwa
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application
| In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application |
| Autore | Baiocchi Marta |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Microbiology (non-medical) |
| Soggetto non controllato |
colorectal cancer
organoids 3D bioprinting patient-derived xenograft cancer-on-chip drug combination cancer stem cells drug resistance clinical trials tumor-initiating cells tumor heterogeneity patient-derived cancer models single-cell RNA-sequencing tumor metabolism transcriptional programs tumor cell differentiation immunotherapy methods chromosomal instability DNA damage targeted therapy decitabine colon cancer DNA methylation clinical translation study machine learning patient-derived tumor organoid precision medicine radiation response rectal cancer PDX model CRC mutation analysis histological examination animal models in vitro culture cancer stem cell methods SATB2 colorectal carcinoma prognosis CDX2 circulating tumor cells CTC cluster size-based method ScreenCell® epithelial mesenchymal transition hypoxia HIF-1α immunofluorescence analysis sequential filtration |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585944103321 |
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Baiocchi Marta
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Bioactive Natural Product Studies—A Southern Hemisphere Perspective
| Marine Bioactive Natural Product Studies—A Southern Hemisphere Perspective |
| Autore | Urban Sylvia |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (142 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Sinularia
Alcyoniidae anticancer activity lobane cembrane diterpene conotoxins ShK toxin ion channels docking molecular dynamics potential of mean force free energy perturbation bioactivity biosynthesis brominated secondary metabolites choline ester indole sea cucumber viscera saponins mass spectrometry MALDI ESI HPCPC triterpene glycosides structure elucidation bioactive compounds marine invertebrate Echinodermata holothurian Cnemidocarpa stolonifera taurine amide PC3 cell line immunofluorescence assay thiaplidiaquinone Aplidium ascidian thiazinoquinone apoptosis Jurkat cytotoxicity malaria farnesyltransferase synthesis thiaplakortone regioisomer tricyclic natural product scaffold X-ray crystal Plasmodium falciparum antiplasmodial cephalostatin mandelalide methicillin resistant Staphylococcus aureus MRSA PK bisindole alkaloids salternamide A (SA) HIF-1α PI3K/Akt/mTOR p42/p44 MAPK STAT3 cell death |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557573903321 |
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Urban Sylvia
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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