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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (594 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
1,2,3-triazole
1,3,4-oxadiazole 3-amino-4'-guanidino 3,4'-bis-guanidino 5-fluoruracil 7-deaza-4'-thioadenosine derivatives acetamide adamantane ADC (antibody-drug conjugate) age alkylated anticancer anticancer activity anticancer agents apoptosis apoptosis induction aromatase inhibitor Bcl-2 inhibitors benzenesulfonamides benzimidazole BRAF breast cancer cancer cancer cell viability cancer vaccine CAR (chimeric antigen receptor) cardiotoxicity carvedilol cell cycle analysis chalcone chalcones colony formation combretastatin A-4 concentration-guided dosing covalent binding CovDock cumulative dose cyclophosphamide cytotoxic activity cytotoxic agents cytotoxicity designed multiple ligand diphenyl ether DNA fragmentation docking doxazosin drug efflux dual inhibitors dual-targeting molecule EGFR ELISA enantioselective synthesis entrectinib exportin-1 gastric adenocarcinoma generic product H1299 HDAC inhibitors HER2 heterocyclic compound histopathology HL-60 HT-29 cells hybrid compounds hybrid molecule hydrazide derivatives imidazoles Imiquimod immunotherapy in vitro in vivo indazole Indole-based analogues inflammation interleukin-6 intramolecular hydrogen bond isolation kidney larotrectinib letrozole MD simulations MDA-MB-231 cells mechanism prediction miR-21 mitoxantrone model informed dosing MTT cytotoxic assay MUC1 MUC16 mucin multi-kinase inhibitor multidrug resistance n/a NaMSA nitrogen scaffolds NTRK nucleoside oxidative stress patent review pemetrexed phenstatin phenyl pyridyl ether physiologically based pharmacokinetics protein kinase inhibitors resin acid solid/lipid nanoparticles sorafenib STAT inhibitors synthesis TDP1 testis thieno[2,3-d][1,2,3]triazine thiourea thymidylate synthase tissue-agnostic Toll-Like Receptor toxicity Trk Trk fusion trypan blue assay tryptophanol tubulin polymerisation inhibitor tumor spheroids tyrosil-DNA-phosphodiesterase 1 urinary bladder USFDA xanthone |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species
| Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species |
| Autore | Nicoletti Rosario |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (134 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
antibacterial
antibacterial activity antifungal activity Aspergillaceae Aspergillus Aspergillus candidus Aspergillus clavatus aspetritone bioactive products bis-indolyl benzenoids BK (Maxi-K) channel breast cancer breviane spiroditerpenoid candidusin chromone coumarin cytotoxic cytotoxicities cytotoxicity diastereomers diterpenoid drug discovery ECD calculations EGFR endophytic fungi gefitinib HER2 hydroxypyrrolidine IDH1 inhibitory activity indole-diterpenoids lapatinib mangrove endophytic fungus mangroves marine-derived fungi n/a NMR data calculations Penicillium raistrickii Penicillium sp. TJ403-1 penitrem A polyketides secondary metabolites sesquiterpenoid sponge-associated fungus sterone Talaromyces Talaromyces purpurogenus thermo-change strategy TNF-? |
| ISBN | 3-03897-981-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346857703321 |
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Nicoletti Rosario
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Deep Learning in Medical Image Analysis
| Deep Learning in Medical Image Analysis |
| Autore | Zhang Yudong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (458 p.) |
| Soggetto non controllato |
1D-convolutional neural network
3D segmentation active surface ARMD artificial intelligence autism bayesian inference black box brain tumor breast cancer cancer cancer prediction cervical cancer change detection classifiers colon cancer computation computed tomography (CT) computer vision computers in medicine convolutional neural network convolutional neural networks COVID-19 CycleGAN data augmentation deep learning deep learning classification dermoscopic images diagnosis diagnostics digital pathology discriminant analysis domain adaptation domain transfer ECG signal detection egocentric camera explainability explainable AI fMRI gibbs sampling glcm matrix HER2 image classification image processing image reconstruction imaging infection detection interpretable/explainable machine learning low-dose lung cancer lung disease detection machine learning machine learning models macroscopic images magnetic resonance imaging (MRI) MCMC medical image analysis medical image segmentation medical images medical imaging melanoma meta-learning microwave breast imaging MRI multimodal learning multiple instance learning musculoskeletal images n/a neo-adjuvant treatment object detection open surgery optimizers PET imaging portable monitoring devices quantitative comparison segmentation shifted-scaled dirichlet distribution skin lesion segmentation sparse-angle surgical tools taxonomy texture analysis transfer learning tumor detection tumour cellularity U-Net unsupervised learning white box whole slide image processing X-ray images XAI |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557435103321 |
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Zhang Yudong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function
| Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function |
| Autore | Pulido Rafael |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (240 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
asthma
astrocytes atypical dual-specificity phosphatases atypical DUSP BDNF brain metastasis cancer cannabinoids circulating tumor cells (CTCs) COPD Cpp1 cytokines DEPArray differentiation dual-specificity phosphatase dual-specificity phosphatases DUSP-4 DUSP10 E. coli infection fungal MKPs granule neurons HDAC6 (histone deacetylase isoform 6) hematopoietic cells HER2 hypertriglyceridemia inflammation influenza integrated omics analysis liver steatosis macrophage macrophages MAP Kinase Phosphatase-2 MAP kinase phosphatases MAP kinases MAPK MAPK phosphatase MAPKs microtubules mitogen-activated protein kinase MK-STYX (MAPK (mitogen-activated protein kinase) phosphoserine/threonine/tyrosine-binding protein) Mkp-1 Msg5 n/a neuroblastoma neuronal differentiation nucleotide receptors P2X7 P2Y13 Pmp1 post-translational modification proliferation protein stability pseudophosphatase respiratory viruses rhinovirus RSV Sdp1 sepsis signaling single cell analysis T cell TLR signaling triple-negative breast cancer (TNBC) ubiquitination |
| ISBN | 3-03921-689-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Dual Specificity Phosphatases |
| Record Nr. | UNINA-9910367740903321 |
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Pulido Rafael
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (480 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
12-deacetyl-12-epi-scalaradial
3-alkylpyridinium polymers A375 and HeLa cell lines A549 cells ABC transporter actinomycin AD0157 adriamycin resistance Aeroplysinin Akt angiogenesis angiogenesis inhibitor ansamycins anthranilic acid anti-angiogenesis anti-angiogenic anti-cancer anti-metastatic activity anti-proliferation anti-proliferative antiangiogenesis antiangiogenic antibacterial Antibody Drug Conjugates (ADCs) anticancer anticancer activity anticancer agent anticancer immunity anticarcinogenic anticoagulant anticoagulation antifouling Antimicrobial peptide (AMP) antioxidant antiproliferative antiproliferative activity antitumor antitumor activities antitumoral antitumour AP-1 apoptosis apoptosis-inducing activity approved antitumor agents araguspongine C arrest of cell cycle Aspergillus autophagy autophagy inducers autophagy inhibitors azoxymethane BCRP/ABCG2 BEL-7402 cell benzo[a]pyrene bioactive natural product bioanalysis bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) bonnethead shark breast cancer breast cancer cells Brevianamide brominated indoles bromophenol buccal gland c-JUN c-Met C15 acetogenins camptothecin cancer Cancer cancer genes cancer preventive cancer progression Cantabrian Sea-derived actinobacteria carbocyclic analogue carcinoembryonic antigen Caribbean sponge carotenoid carotenoids caspase cascade cell adhesion cell adhesion molecules cell cycle cell cycle arrest cell migration cembranoids chemical conjugation chemoprevention chemopreventive chemosensitization chemotherapy chimera CHOP chromatography circulating tumor cells cisplatin clinical trials colorectal cancer cooperative binding cyclin D1 cyclin-dependent kinase CYP1A1 cystatin F cystatin superfamily cytokine release cytoskeleton cytotoxic activity cytotoxicity deep-sea depolymerisation dibromotyrosine dieckol divergolides DNA minor groove binder drug discovery Ecklonia cava elisidepsin EMT endoperoxide endophytic fungus endothelial cells energy stress epigonal organ epithelial-mesenchymal transition ER-stress ET-743 evolution FAK fascaplysin fatty acid 2-hydroxylase fatty acids FAU FBDD fucoidan fucoxanthin fumigaclavine C gemcitabine gene expression glioblastoma gliotoxin glucocorticoid receptor glycosaminoglycans gorgonian Haliclona gracilis HeLa cells heparan sulphate heparanase hepatocellular carcinoma HER2 HIF-1 hippuristanol HSP90 human lung cancer human normal diploid fibroblast (TIG-1 cells) human sarcoma cell line (HT1080 cells) humulane sesquiterpenoids hybridization hydroxylated lipids hypoxia hypoxia-inducible factor-1 IL-6 in vivo model inflammation inhibitor integrin β1 invasion isatin Isofistularin itampolin A jaspine B JNK1/2 Jurkat kalkitoxin kunitz type inhibitor Lampetra morii Leathesia nana Leptogorgia leukemia lipid rafts low molecular weight fucoidan extract low toxic LS-1 lung cancer lung metastasis Lyngbya majuscula macrolide mangrove-derived actinomycete manzamine A MAPK/ERK pathway marangucyclines marine antitumor agents marine biotechnology marine compound marine drug marine drugs marine fungus marine metabolites marine mollusc marine natural products marine organisms marine sponges marine-derived drugs Marthasterias glacialis L. MCP-1 mechanisms of action melanoma membrane permeabilization metastasis microalgae Micromonospora migration mitochondria mitochondria toxin mitochondrial pathway mitochondrial dysfunction molecular docking molecular mechanisms molecular modeling molecular oncology Moorea producens MRP1/ABCC1 multi-drug resistant leukemia multidrug resistance Mycalin A Mycochromenic acid derivative N-Ras n/a nanoparticle naphthopyrones natural marine compounds natural product natural products neuroblastoma-rat sarcoma NF-κB NF-κB signaling nicotine nicotinic acetylcholine receptor non-small cell lung cancer non-small cell lung cancer (NSCLC) non-small cell lung carcinoma nonfunctioning pituitary adenomas novel inhibitor NSCLC Nur77 osteosarcoma oxidative stress oxidative stress P-gp/ABCB1 P2X7 receptor p38 p38/ERK p38α p65 pachastrissamine palmitic acid paulomycins pazopanib PEL Penicillium brevicompactum Penicillium paneum phase I pheochromocytoma and paraganglioma phlorotannins phycocyanin PI3K/Akt plakortide plitidepsin pollution poly(ADP-ribose)-polymerase inhibitor polyoxygenated steroids polyphenols polysaccharides Porifera porifera/sponge preclinical programmed cell death programmed cell death-ligand 1 programmed cell death-ligand 2 proliferation prostate cancer proteasomal degradation proteomic pseudopterosin puupehenones pyrrolidinedione reactive oxygen species RGD motif ribosomal protein genes ROS RPS30 safety Sarcophyton ehrenbergi sea anemone sea cucumbers seaweed secondary metabolites sediment selenium-containing polysaccharide-protein complex Sepia ink polysaccharides shrimp signal transduction sinulariolide sipholenol A small cell lung cancer SNORA62 snoRNA SNU-C5/5-FU soft coral soft tissue sarcoma soft tissue sarcoma sphingosine kinase inhibitor sponge sponges STAT3 Streptomyces sp. SCSIO 11594 synergism synthetic analogues SZ-685C targeted therapy terpenes tetracenomycin X TGF-β signaling Thalassia testudinum thalassiolin B therapeutic compounds Tilapia piscidin 4 (TP4) TNFα Topo I inhibitor topoisomerase trabectedin triterpene glycosides TRPM7 tumor cell line tumor microenvironment tumor-associated macrophages Ulva fasciata uveal melanoma VEGF virtual screening xyloketal B α9-nicotinic acetylcholine receptors (nAChRs) αO-conotoxin GeXIVA β1-integrin λ-carrageenan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oncolytic Virus Immunotherapy
| Oncolytic Virus Immunotherapy |
| Autore | Marchini Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (366 p.) |
| Soggetto topico |
Clinical and internal medicine
Medicine and Nursing |
| Soggetto non controllato |
adenovirus
adoptive T cell therapy antigen-agnostic vaccination antitumor immune response arming biomarkers cancer cancer immune therapy cancer immunotherapy cancer therapy CAR T cell checkpoint inhibitor checkpoint inhibitors class I HLA clinical trials colorectal cancer combination therapy combinatory therapy CTLA-4 delivery DNA methyltransferase inhibitor (DNMTi) epigenetic silencing genetic modification glioblastoma HER2 herpes simplex virus HSV-1 immune checkpoint blockade immune checkpoint inhibitor immunoediting immunogenic cell death immunostimulatory immunosurveillance immunotherapy measles virus melanoma multi-stage n/a NDV newcastle disease virus oncogenic signaling oncolytic oncolytic adenovirus oncolytic virus oncolytic viruses pancreatic cancer pancreatic ductal adenocarcinoma parvovirus PD-1 PD-L1 personalized oncolyticvirotherapy RAS reovirus retargeted virus small molecule targeting tropism retargeting tumor tumor microenvironment type I interferon vaccination vector engineering vesicular stomatitis virus viral mimicry virotherapy αvβ6 integrin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566462203321 |
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Marchini Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules
| Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules |
| Autore | Das Diganta B |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (220 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
alginate
alginate gelispheres anti-tumor antimicrobial activity antimicrobial delivery antitumoral activity aqueous humor arsenic trioxide bio-imaging bioactive molecules biofilm biofunctionalization biomimetic magnetite carbon dots citric acid coaxial electrospraying coculture composite crosslinked matrices curcumin direct emulsification double coating layer drug delivery drug delivery systems drug skin permeation Franz cells HER2 isoniazid loxoprofen magnetic hyperthermia magnetite MamC membranes microfluidics microparticulate mixture design N-hydroxyphthalimide n/a nanoemulsion nanofibers nanoparticles nanoparticles stability pediatric drug delivery pharmaceutical particulates pharmacokinetic studies PLGA discs pluronic F68 polymer gels polymer-lipid polymeric membrane polymeric nanoparticles polystyrene µPs polyvinylpyrrolidone powder flow properties process-property-performance relationship prolonged release pseudomonas aeruginosa reconstitutable dry suspension red blood cells membrane reduce toxicity sodium alginate nanoparticles spreading angle sustained release pellets tape stripping textural analysis tuberculosis wound dressing wound infection |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557141103321 |
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Das Diganta B
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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